keyword
https://read.qxmd.com/read/38536136/pediatric-injury-trends-in-rhode-island-during-the-covid-19-pandemic
#1
JOURNAL ARTICLE
Jeffrey R Savarino, Holly R Hanson, Wendy J Pomerantz, Mark R Zonfrillo, Margaret K Formica, Stephanie M Ruest
BACKGROUND: Pediatric Emergency Department (PED) visits nationally decreased while the proportion of injury-related PED visits increased during the COVID-19 pandemic. Little is known about the trends in Rhode Island (RI). METHODS: This is a planned sub-analysis of RI data from a retrospective study of pediatric injury-related visits to 40 PEDs for children <18 years old from January 2019-December 2020. We calculated frequencies and compared patient demographics, injury types, severity, and mechanisms for 3/17/2019-12/31/2019 (pre-COVID-19) versus 3/15/2020-12/31/2020 (study period)...
April 1, 2024: Rhode Island Medical Journal
https://read.qxmd.com/read/38534491/reimagining-radiology-a-comprehensive-overview-of-reviews-at-the-intersection-of-mobile-and-domiciliary-radiology-over-the-last-five-years
#2
REVIEW
Graziano Lepri, Francesco Oddi, Rosario Alfio Gulino, Daniele Giansanti
(Background) Domiciliary radiology, which originated in pioneering studies in 1958, has transformed healthcare, particularly during the COVID-19 pandemic, through advancements such as miniaturization and digitization. This evolution, driven by the synergy of advanced technologies and robust data networks, reshapes the intersection of domiciliary radiology and mobile technology in healthcare delivery. (Objective) The objective of this study is to overview the reviews in this field with reference to the last five years to face the state of development and integration of this practice in the health domain...
February 24, 2024: Bioengineering
https://read.qxmd.com/read/38534377/granular-insights-neutrophil-predominance-and-elastase-release-in-severe-asthma-exacerbations-in-a-pediatric-cohort
#3
JOURNAL ARTICLE
Kirstin Henley, Erin Tresselt, Jessica S Hook, Parth A Patel, Michelle A Gill, Jessica G Moreland
The chronic inflammatory component of asthma is propagated by granulocytes, including neutrophils and eosinophils, in the peripheral circulation and airway. Previous studies have suggested that these cells have an altered expression of adhesion-related molecules and a propensity for the release of granule contents that may contribute to tissue damage and enhance inflammatory complications in patients with status asthmaticus. The goal of this prospective cohort study at a tertiary care pediatric hospital with a large population of asthma patients was to assess the role of granulocyte-based inflammation in the development of asthma exacerbation...
March 18, 2024: Cells
https://read.qxmd.com/read/38534003/low-acuity-pediatric-emergency-department-utilization-caregiver-motivations
#4
JOURNAL ARTICLE
Lisa Ziemnik, Noah Parker, Kyra Bufi, Kristen Waters, Jacob Almeda, Adrienne Stolfi
OBJECTIVES: Proper emergency department (ED) utilization is a hallmark of population health. Emergency department overcrowding due to nonurgent visits causes increased stress to healthcare staff, higher costs, and longer wait times for more urgent cases. This study sought to better understand post pandemic reasons caregivers have when bringing in their children for nonurgent visits and devise effective interventions to improve caregiver choice for non-ED care for nonurgent conditions...
March 27, 2024: Pediatric Emergency Care
https://read.qxmd.com/read/38533633/clinical-trial-randomized-controlled-trial-of-linaclotide-in-children-aged-6-17-years-with-functional-constipation
#5
JOURNAL ARTICLE
Carlo Di Lorenzo, Samuel Nurko, Jeffrey S Hyams, Gerardo Rodriguez-Araujo, Cristina Almansa, Valentina Shakhnovich, Miguel Saps, Michael Simon
OBJECTIVES: Linaclotide, a guanylate cyclase-C agonist, was recently approved in the United States for treatment of children 6-17 years old with functional constipation (FC). This study evaluated the safety and efficacy of several linaclotide doses in children 6-17 years old with FC. METHODS: In this multicenter, randomized, double-blind, placebo-controlled phase 2 study, 173 children with FC (based on Rome III criteria) were randomized to once-daily linaclotide (A: 9 or 18 μg, B: 18 or 36 μg, or C: 36 or 72 μg) or placebo in a 1:1:1:1 ratio for 6- to 11-year-olds (dosage determined by weight: 18 to <35 or ≥35 kg) and linaclotide (18, 36, 72, or 145 μg) or placebo in a 1:1:1:1:1 ratio for 12- to 17-year-olds...
March 27, 2024: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/38533571/reducing-time-to-postintubation-sedation-in-a-pediatric-emergency-department
#6
JOURNAL ARTICLE
Claci Ayers, David P Johnson, Lacey Noffsinger, S Barron Frazier
BACKGROUND AND OBJECTIVE: Inadequate postintubation sedation (PIS) can lead to unplanned extubations, conscious paralysis, and overall unsafe care of patients. From 2018 to 2020, we realized at our hospital that ∼25% of children received sedation in an adequate time frame in the pediatric emergency department, with 2 unplanned dislodgements of the endotracheal tube. Our objective was to reduce time to initiating PIS from a mean of 39 minutes to less than 15 minutes in our pediatric emergency department by September 2021...
March 27, 2024: Pediatrics
https://read.qxmd.com/read/38533563/direct-admission-program-implementation-a-qualitative-analysis-of-variation-across-health-systems
#7
JOURNAL ARTICLE
Jordan A Taylor, Corrie E McDaniel, Cathryn A Stevens, Elizabeth Jacob-Files, Stephanie C Acquilano, Seneca D Freyleue, Ryan Bode, Guliz Erdem, Kristyn Felman, Stephanie Lauden, Martha L Bruce, JoAnna K Leyenaar
OBJECTIVES: Direct admission (DA) to the hospital has the potential to improve family satisfaction and timeliness of care by bypassing the emergency department. Using the RE-AIM implementation framework, we sought to characterize variation across health systems in the reach, effectiveness, adoption, and implementation of a DA program from the perspectives of parents and multidisciplinary clinicians. METHODS: As part of a stepped-wedge cluster randomized trial to compare the effectiveness of DA to admission through the emergency department, we evaluated DA rates across 69 clinics and 3 health systems and conducted semi-structured interviews with parents and clinicians...
March 27, 2024: Pediatrics
https://read.qxmd.com/read/38533560/reducing-antibiotic-duration-for-uncomplicated-uti-in-the-pediatric-emergency-department
#8
JOURNAL ARTICLE
Gagandeep K Kooner, Marissa Bass, Vivek Saroha, P J Gonzalez, Shabnam Jain
BACKGROUND: Short-duration (3-5 days) antibiotic treatment of uncomplicated urinary tract infection (uUTI) in children >24 months of age is equivalent to longer-duration antibiotic treatment, with added benefits of antibiotic stewardship. At our pediatric emergency department (ED), 13% of 5- to 18-year-old patients discharged with uUTI received ≤5 days of antibiotics. We aimed to increase short-duration prescriptions in patients with uUTI from 13% to >50% over 12 months. METHODS: This quality improvement project was conducted from January 2021 to August 2022...
March 27, 2024: Hospital Pediatrics
https://read.qxmd.com/read/38532939/safety-and-efficacy-of-recombinant-fusion-protein-linking-coagulation-factor-ix-with-albumin-rix-fp-in-previously-untreated-patients-with-hemophilia-b
#9
JOURNAL ARTICLE
Richard Lemons, Michael Wang, Julie Curtin, Lynda Mae Lepatan, Christoph Male, Flora Peyvandi, Mario von Depka Prondzinski, Rongrong Wang, William McKeand, Wilfried Seifert, Johannes Oldenburg
Introduction  Recombinant fusion protein linking coagulation factor IX (FIX) with albumin (rIX-FP) has been shown to be an effective, well-tolerated treatment for patients with severe hemophilia B who had previously received factor replacement therapy. This study investigated the safety and efficacy of rIX-FP in previously untreated patients (PUPs). Methods  Patients with moderately severe/severe hemophilia B (≤2% FIX) previously untreated with FIX replacement products received rIX-FP (25-75 IU/kg) prophylaxis weekly or on-demand treatment over ≥50 exposure days (EDs)...
January 2024: TH Open: Companion Journal to Thrombosis and Haemostasis
https://read.qxmd.com/read/38532744/the-use-of-preoperative-video-distraction-on-emergence-delirium-in-preschool-children-undergoing-strabismus-surgery-under-anesthesia-with-sevoflurane-a-randomized-controlled-trial
#10
Yue Wang, Liyan Chu, He Li, Yingjie Du, Shanshan Wang, Ying Liu, Guyan Wang
PURPOSE: The aim of this study was to determine whether preoperative video distraction reduces the incidence of emergence delirium in preschool children under general anesthesia with sevoflurane. PATIENTS AND METHODS: In this prospective randomized controlled study, children aged 3-6 years were randomized to receive either video distraction (Group V) or common clinical practice (Group C) from arrival at the holding area to induction of anesthesia. The primary outcome was the incidence of emergence delirium...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38532147/prediction-of-short-and-long-term-outcomes-using-pre-operative-ventricular-size-in-infants-with-post-hemorrhagic-ventricular-dilation
#11
JOURNAL ARTICLE
Molly Serebin, Jian Zhang, Ke Yan, Erwin Cabacungan, Tejaswini Deshmukh, Mohit Maheshwari, Andrew Foy, Susan Cohen
PURPOSE: Post-hemorrhagic ventricular dilation (PHVD) leads to developmental delays in premature infants, yet the optimal timing of neurosurgical interventions is unknown. Neuroimaging modalities have emerged to delineate injury and follow the progression of PHVD. Fronto-temporal horn ratio (FTHR) is used as a marker of ventricular dilation and can be a standardized tool to direct the timing of neurosurgical intervention. Our study determined a pre-operative FTHR measurement threshold to predict short- and long-term outcomes...
March 27, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://read.qxmd.com/read/38531955/continuous-monitoring-of-physiological-data-using-the-patient-vital-status-fusion-score-in-septic-critical-care-patients
#12
JOURNAL ARTICLE
Philipp L S Ohland, Thomas Jack, Marcel Mast, Anette Melk, André Bleich, Steven R Talbot
Accurate and standardized methods for assessing the vital status of patients are crucial for patient care and scientific research. This study introduces the Patient Vital Status (PVS), which quantifies and contextualizes a patient's physical status based on continuous variables such as vital signs and deviations from age-dependent normative values. The vital signs, heart rate, oxygen saturation, respiratory rate, mean arterial blood pressure, and temperature were selected as input to the PVS pipeline. The method was applied to 70 pediatric patients in the intensive care unit (ICU), and its efficacy was evaluated by matching high values with septic events at different time points in patient care...
March 26, 2024: Scientific Reports
https://read.qxmd.com/read/38531631/paramedics-success-and-complications-in-prehospital-pediatric-intubation-a-meta-analysis
#13
REVIEW
Faisal A AlGhamdi, Nasser A AlJoaib, Abdulaziz M Saati, Mishal A Abu Melha, Mohammad A Alkhofi
BACKGROUND: Prehospital pediatric intubation is a potentially life-saving procedure in which paramedics are relied upon. However, due to the anatomical nature of pediatrics and associated adverse events, it is more challenging compared to adult intubation. In this study, the knowledge and attitude of paramedics was assessed by measuring their overall success rate and associated complications. METHODS: An online search using PubMed, Scopus, Web of Science, and Cochrane CENTRAL was conducted using relevant keywords to include studies that assess success rates and associated complications...
March 27, 2024: Prehospital and Disaster Medicine
https://read.qxmd.com/read/38531618/high-sensitive-troponint-interleukin-8-and-interleukin-6-link-with-post-surgery-risk-in-infant-heart-surgery
#14
JOURNAL ARTICLE
Elin M Thorlacius, Juho Keski-Nisula, Maria Vistnes, Tiina Ojala, Mattias Molin, Mats Synnergren, Birgitta S Romlin, Sven-Erik Ricksten, Håkan Wåhlander, Albert Gyllencreutz Castellheim
BACKGROUND: This study focuses on biomarkers in infants after open heart surgery, and examines the association of high-sensitive troponin T (hs-cTnT), interleukin-6 (IL-6), and interleukin-8 (IL-8) with postoperative acute kidney injury (AKI), ventilatory support time and need of vasoactive drugs. METHODS: Secondary exploratory study from a double-blinded clinical randomized trial (Mile-1) on 70 infants undergoing open heart surgery with cardiopulmonary bypass (CPB)...
March 26, 2024: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/38531164/clinical-characteristics-and-appropriateness-of-investigations-in-children-with-headaches-at-the-emergency-department
#15
JOURNAL ARTICLE
Hanan Azouz, Wafaa Muhammed, Marwa Abd Elmaksoud
BACKGROUND: Identifying the cause of headaches in pediatric emergency departments (PEDs) can be challenging due to the lack of comprehensive research. This study aims to identify the frequency, characteristics, and unnecessary diagnostic procedures of patients with headaches in the PED setting. METHODS: A six-month cross-sectional study was conducted at the PED of Alexandria University Children's Hospital, including all children with headaches. Children were classified as having primary headache (PH), secondary benign headache (SBH), and secondary serious headache (SSH) according to predetermined criteria...
March 5, 2024: Pediatric Neurology
https://read.qxmd.com/read/38530699/universal-suicidality-screening-in-a-pediatric-emergency-department-to-improve-mental-health-safety-risk
#16
JOURNAL ARTICLE
Lauren Do, Karen Piper, Amanda N Barczyk, Jeffrey D Shahidullah, Karla A Lawson
INTRODUCTION: Suicide is the second leading cause of death for youth 12 to 18 years of age. Suicidal ideation can be predictive of suicide attempt, so screening for suicidal ideation by emergency nurses can help identify those at risk and facilitate timely intervention. This study evaluates the use of a universal suicide screening using the Patient Safety Screener 3 and the Columbia Suicide Severity Rating Scale to identify youth ages 12 to 18 years experiencing suicide risk and assess factors predictive of suicide risk level...
March 25, 2024: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
https://read.qxmd.com/read/38530410/management-of-pancreatic-and-duodenal-trauma-in-childhood-a-university-hospital-experience-over-a-10-year-period
#17
JOURNAL ARTICLE
Agah Koray Mansiroglu, Emrullah Cesur, Binali Firinci, Ozgur Caglar, Murat Yigiter, Ahmet Bedii Salman
PURPOSE: Duodenal/pancreatic injuries occur in less than 10% of intra-abdominal injuries in pediatric blunt trauma. Isolated duodenal/pancreatic injuries occur in two-thirds of cases, while combined injuries occur in the remaining. This study aimed to investigate pediatric patients with pancreatic and duodenal trauma. METHODS: Data from 31 patients admitted to Atatürk University, Medical Faculty, Department of Pediatric Surgery for pancreatic/duodenal trauma between 2010 and 2019 were retrospectively analyzed...
March 26, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38530035/adolescent-and-caregiver-perceptions-of-addressing-mental-health-in-inflammatory-bowel-disease
#18
JOURNAL ARTICLE
Catalina Berenblum Tobi, Maihan Vu, Maria E Díaz-González de Ferris, Sherritta Semerzier, Michael D Kappelman, Neal A deJong
Adolescents with inflammatory bowel disease (IBD) are at an increased risk of anxiety and depression compared to peers, but availability of mental health services in IBD clinics does not meet patients' needs, and use of primary care services for mental health screening and care is low. This study provides qualitative data regarding adolescent and caregiver perspectives on addressing mental health in IBD. Interviews were conducted with adolescents with IBD and caregivers of adolescents with IBD. Interview transcripts were coded and analyzed for prominent themes...
March 26, 2024: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://read.qxmd.com/read/38529810/medulloblastoma-in-a-child-with-osteoma-cutis%C3%A2-a-rare-association-due-to-loss-of-gnas-expression
#19
Jananie Suntharesan, Ekaterina Lyulcheva-Bennett, Rachel Hart, Barry Pizer, James Hayden, Renuka Ramakrishnan
OBJECTIVES: Inactivating GNAS mutations result in varied phenotypes depending on parental origin. Maternally inherited mutations typically lead to hormone resistance and Albright's hereditary osteodystrophy (AHO), characterised by short stature, round facies, brachydactyly and subcutaneous ossifications. Paternal inheritance presents with features of AHO or ectopic ossification without hormone resistance. This report describes the case of a child with osteoma cutis and medulloblastoma...
March 27, 2024: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://read.qxmd.com/read/38529050/manual-reduction-in-testicular-torsion-and-subsequent-treatment-after-successful-reduction-a-series-of-reports-in-a-single-institution
#20
JOURNAL ARTICLE
Xiaokang Qi, Junjie Yu, Xuefei Ding, Yehua Wang, Haiyan Zhu
INTRODUCTION: To explore the factors affecting the success of testicular torsion manual reduction and the safety of subsequent conservative treatment after successful reduction. METHODS: Clinical data of 66 patients with testicular torsion treated in our emergency department from February 2017 to February 2022 were retrospectively collected. Manual reduction without anesthesia was performed in 19 patients. Patients with successful manual reduction chose different subsequent treatments according to the wishes of themselves and their guardians, including continuing conservative treatment and surgical exploration...
2024: Frontiers in Pediatrics
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