keyword
https://read.qxmd.com/read/33787631/conservative-treatment-and-outcome-of-upper-cervical-spine-fractures-in-young-children-a-strobe-compliant-case-series
#21
MULTICENTER STUDY
Ryszard Tomaszewski, Sergio B Sesia, Daniel Studer, Erich Rutz, Johannes M Mayr
Cervical spine (C-spine) fractures in young children are very rare, and little information on treatment modalities and functional, radiographic, and patient-reported outcome exists. In this 2-center, retrospective case series, we assessed subjective and functional mid-term outcomes in children aged ≤5 years whose C-spine fractures were treated nonoperatively.Between 2000 and 2018, 6 children (median age at injury: 23.5 months; range: 16-31 months) with C1 or C2 injuries were treated with Minerva cast/brace or soft collar brace at 1 of the 2 study centers...
April 2, 2021: Medicine (Baltimore)
https://read.qxmd.com/read/33034503/dijet-resonance-search-with-weak-supervision-using-sqrt-s-13-tev-pp-collisions-in-the-atlas-detector
#22
JOURNAL ARTICLE
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Y Yasu, E Yatsenko, H Ye, J Ye, S Ye, I Yeletskikh, M R Yexley, E Yigitbasi, P Yin, K Yorita, K Yoshihara, C J S Young, C Young, J Yu, R Yuan, X Yue, M Zaazoua, B Zabinski, G Zacharis, E Zaffaroni, J Zahreddine, A M Zaitsev, T Zakareishvili, N Zakharchuk, S Zambito, D Zanzi, D R Zaripovas, S V Zeißner, C Zeitnitz, G Zemaityte, J C Zeng, O Zenin, T Ženiš, D Zerwas, M Zgubič, B Zhang, D F Zhang, G Zhang, J Zhang, Kaili Zhang, L Zhang, L Zhang, M Zhang, R Zhang, S Zhang, X Zhang, X Zhang, Y Zhang, Z Zhang, Z Zhang, P Zhao, Z Zhao, A Zhemchugov, Z Zheng, D Zhong, B Zhou, C Zhou, H Zhou, M S Zhou, M Zhou, N Zhou, Y Zhou, C G Zhu, C Zhu, H L Zhu, H Zhu, J Zhu, Y Zhu, X Zhuang, K Zhukov, V Zhulanov, D Zieminska, N I Zimine, S Zimmermann, Z Zinonos, M Ziolkowski, L Živković, G Zobernig, A Zoccoli, K Zoch, T G Zorbas, R Zou, L Zwalinski
This Letter describes a search for narrowly resonant new physics using a machine-learning anomaly detection procedure that does not rely on signal simulations for developing the analysis selection. Weakly supervised learning is used to train classifiers directly on data to enhance potential signals. The targeted topology is dijet events and the features used for machine learning are the masses of the two jets. The resulting analysis is essentially a three-dimensional search A→BC, for m_{A}∼O(TeV), m_{B},m_{C}∼O(100  GeV) and B, C are reconstructed as large-radius jets, without paying a penalty associated with a large trials factor in the scan of the masses of the two jets...
September 25, 2020: Physical Review Letters
https://read.qxmd.com/read/32958153/accessory-tragus-a-rare-congenital-anomaly-in-a-dog
#23
JOURNAL ARTICLE
B H Lee, A T Massa, K R Taylor
Accessory tragus is a congenital malformation of part of the external ear, commonly reported in humans. Clinically, it is a benign, cutaneous mass located anywhere between the tragus of the ear and the angle of the mouth, along the migratory path of the first branchial arch. An accessory tragus was diagnosed in an otherwise healthy six-month-old male castrated American pit bull terrier that had a haired, pedunculated cutaneous mass on the left maxillary region from birth. Histologically, the mass was a polypoid extension of histologically normal haired skin with a central core of subcutaneous adipose tissue and well-differentiated elastic cartilage...
August 2020: Journal of Comparative Pathology
https://read.qxmd.com/read/32736597/protect-trial-a-cluster-randomized-study-with-hydroxychloroquine-versus-observational-support-for-prevention-or-early-phase-treatment-of-coronavirus-disease-covid-19-a-structured-summary-of-a-study-protocol-for-a-randomized-controlled-trial
#24
COMPARATIVE STUDY
Oriana Nanni, Pierluigi Viale, Bernadette Vertogen, Claudia Lilli, Chiara Zingaretti, Caterina Donati, Carla Masini, Manuela Monti, Patrizia Serra, Roberto Vespignani, Veruska Grossi, Annibale Biggeri, Emanuela Scarpi, Francesca Galardi, Lucia Bertoni, Americo Colamartini, Fabio Falcini, Mattia Altini, Ilaria Massa, Raffaella Gaggeri, Giovanni Martinelli
OBJECTIVES: Hydroxychloroquine has shown to have antiviral activity in vitro against coronaviruses, specifically SARS-CoV-2. It is believed to block virus infection by increasing endosomal pH required for virus cell fusion and glycosylation of viral surface proteins. In addition to its antiviral activity, hydroxychloroquine has an immune-modulating activity that may synergistically enhance its antiviral effect in vivo, making it a potentially promising drug for the prevention and the cure of SARS-CoV-19...
July 31, 2020: Trials
https://read.qxmd.com/read/32446620/craniopharyngiomas-experience-and-results
#25
JOURNAL ARTICLE
D Massa, M Glerean, J Rasmussen, M Altszul, P Fainstein-Day, P Ajler
INTRODUCTION: Craniopharyngiomas are a big challenge in the neurosurgical field. Because these lesions involve important systems, surgeons must weigh the risks of aggressive resection against the long-term challenges of recurrence. We present the outcomes of our patients based on clinical results, degree of resection, recurrence and disease-free survival. MATERIALS AND METHODS: We reviewed medical records in all patients who had undergone surgical resection for craniopharyngioma at (Hospital Italiano de Buenos Aires) between 2007 and 2019...
2021: Neurocirugía (English Edition)
https://read.qxmd.com/read/31692814/the-prevalence-of-syphilis-in-hiv-seropositive-patients-a-retrospective-study-at-the-regional-hospital-in-agadir-morocco
#26
JOURNAL ARTICLE
Mohamed Bourouache, Rachida Mimouni, Mohamed Nejmeddine, Smail Chadli, Fatima Benlmeliani, Jamila Sardi, Mourad Malmoussi, Zineb Ouagari, Maryam El Basbassi, Mohamed Aghrouch
Introduction: HIV and syphilis are major public health problems in Morocco. The region of Souss-Massa, south-west of the country, hold more than 24% of HIV seropositive cases registered in Morocco during 2009. The aim of this study is to evaluate the seroprevalence of syphilis among HIV seropositive patients in the region of Souss-Massa, south-west of Morocco. Methods: To evaluate the seroprevalence of syphilis and neurosyphilis among HIV seropositive patients, we retrospectively investigated the medical records of HIV-infected patients attending the regional hospital located in the city of Agadir, during the period comprised between 2011 and 2016...
2019: Pan African Medical Journal
https://read.qxmd.com/read/31400435/effects-of-temperature-on-the-reproductive-physiology-of-female-elasmobranchs-the-case-of-the-narrownose-smooth-hound-shark-mustelus-schmitti
#27
JOURNAL ARTICLE
Mariano Elisio, Cynthia A Awruch, Ana M Massa, Gustavo J Macchi, Gustavo M Somoza
The knowledge of how temperature influences elasmobranchs reproductive physiology allows a better understanding of their reproductive patterns. This study describes the relationship between temperature fluctuations and the plasmatic changes of the sex steroids related to reproduction: testosterone (T), estradiol (E2 ) and progesterone (P4 ), throughout the female reproductive cycle of the shark Mustelus schmitti. A total of 123 adult females were bi-monthly sampled in Buenos Aires, Argentina, coastal waters...
December 1, 2019: General and Comparative Endocrinology
https://read.qxmd.com/read/30691506/the-effect-of-malaria-rapid-diagnostic-tests-results-on-antimicrobial-prescription-practices-of-health-care-workers-in-burkina-faso
#28
JOURNAL ARTICLE
Massa Dit Achille Bonko, Francois Kiemde, Marc Christian Tahita, Palpouguini Lompo, Athanase M Some, Halidou Tinto, Michael Boele van Hensbroek, Petra F Mens, Henk D F H Schallig
BACKGROUND: Malaria rapid diagnostic tests (RDT) are widely used in endemic areas in order to comply with the recommendation that malaria treatment should only be given after the clinical diagnosis has been confirmed by RDT or microscopy. However, the overestimation of malaria infection with the use of PfHRP2 based RDT, makes the management of febrile illnesses more challenging. This study aimed to assess the effect of the use of malaria RDT on antimicrobial prescription practices. METHODS: A prospective study was conducted among febrile children under-5 years of age attending four health facilities and the referral hospital in the Nanoro Health District (Burkina Faso)...
January 28, 2019: Annals of Clinical Microbiology and Antimicrobials
https://read.qxmd.com/read/30611712/low-dose-radiotherapy-for-extranodal-marginal-zone-b-lymphoma-of-the-lip-case-report-and-literature-review
#29
REVIEW
Lavinia Bianco, Salvatore Dario Solla, Guido Parvis, Eva Gino, Enrico Bollito, Andrea Riccardo Filippi, Francesca Massa, Maria Grazia Ruo Redda
Non-Hodgkin lymphoma (NHL) of the lip is extremely rare. It is usually indolent and in early stages a local approach is often indicated. We present a case report of a patient with extranodal NHL of the lip treated with chemotherapy and low-dose radiation treatment (RT). The patient was affected by B-cell NHL of the marginal zone, Stage IAE. After a few months of observation with progressive disease, the patient was submitted to two cycles of chemotherapy with no response. Therefore, he was treated with very low-dose RT consisting of two fractions of 2 Gy...
March 2021: Hematology/oncology and Stem Cell Therapy
https://read.qxmd.com/read/29909610/geographical-distribution-of-health-indicators-related-to-snake-bites-and-envenomation-in-morocco-between-1999-and-2013
#30
JOURNAL ARTICLE
Faiçal El Hattimy, Fouad Chafiq, Hinde Hami, Abdelghani Mokhtari, Abdelmajid Soulaymani, Soulaymani Bencheikh Rachida
OBJECTIVES: Envenomation from snake bites is a significant cause of morbidity and mortality worldwide. The aim of this study was to describe the epidemiological features of snake bites in Morocco and to evaluate time-space trends in snake bite incidence, the mortality rate, and the case-fatality rate. METHODS: This is a retrospective study of snake bite cases reported to the Moroccan Poison Control Center between 1999 and 2013. RESULTS: During the study period, 2,053 people were bitten by snakes in Morocco...
2018: Epidemiology and Health
https://read.qxmd.com/read/27880982/safety-and-efficacy-of-ruxolitinib-in-splanchnic-vein-thrombosis-associated-with-myeloproliferative-neoplasms
#31
JOURNAL ARTICLE
Lisa Pieri, Chiara Paoli, Umberto Arena, Fabio Marra, Fabio Mori, Mery Zucchini, Stefano Colagrande, Alessandro Castellani, Arianna Masciulli, Vittorio Rosti, Valerio De Stefano, Silvia Betti, Guido Finazzi, Maria Luisa Ferrari, Elisa Rumi, Marco Ruggeri, Ilaria Nichele, Paola Guglielmelli, Rajmonda Fjerza, Carmela Mannarelli, Tiziana Fanelli, Lucia Merli, Giuditta Corbizi Fattori, Margherita Massa, Giuseppe Cimino, Alessandro Rambaldi, Giovanni Barosi, Mario Cazzola, Tiziano Barbui, Alessandro M Vannucchi
Splanchnic vein thrombosis (SVT) is one of the vascular complications of myeloproliferative neoplasms (MPN). We designed a phase 2 clinical trial to evaluate safety and efficacy of ruxolitinib in reducing splenomegaly and improving disease-related symptoms in patients with MPN-associated SVT. Patients diagnosed with myelofibrosis (12 cases), polycythemia vera (5 cases) and essential thrombocythemia (4 cases) received ruxolitinib for 24 weeks in the core study period. Spleen volume was assessed by magnetic resonance imaging (MRI) and splanchnic vein circulation by echo-Doppler analysis...
February 2017: American Journal of Hematology
https://read.qxmd.com/read/27858385/third-ventricle-floor-variations-and-abnormalities-in-myelomeningocele-associated-hydrocephalus-our-experience-with-455-endoscopic-third-ventriculostomy-procedures
#32
JOURNAL ARTICLE
Volkan Etus, Tugba Morali Guler, Hakan Karabagli
AIM: To evaluate the incidence of anatomical variations and abnormalities of the third ventricle floor encountered during the endoscopic third ventriculostomy (ETV) procedure in myelomeningocele-associated hydrocephalus (MAH) cases. MATERIAL AND METHODS: A retrospective analysis was performed on 455 pediatric MAH cases that had been treated with ETV. This case series consisted of the patients who were initially treated with ETV and also those who were treated with ETV for the management of cerebrospinal fluid shunt dysfunction...
2017: Turkish Neurosurgery
https://read.qxmd.com/read/27683769/effects-of-long-term-roux-en-y-gastric-bypass-on-body-weight-and-clinical-metabolic-comorbidities-in-bariatric-surgery-service-of-a-university-hospital
#33
JOURNAL ARTICLE
Cátia Ferreira da Silva, Larissa Cohen, Luciana d'Abreu Sarmento, Felipe Monnerat Marino Rosa, Eliane Lopes Rosado, João Régis Ivar Carneiro, Antônio Augusto Peixoto de Souza, Fernanda Cristina Carvalho Mattos Magno
Background: Due to the high failure rate observed in the clinical treatment of morbid obesity an increase in bariatric surgery indications, as an alternative for the control of obesity and comorbidities, is noticeable. Aim: To evaluate the performance of type 2 diabetes mellitus, high blood pressure and dyslipidemia in patients submitted to Roux-en-Y gastric bypass in late follow-up. Methods: Retrospective analysis of 59 patients included in the bariatric surgery program...
2016: Brazilian Archives of Digestive Surgery: ABCD
https://read.qxmd.com/read/27438034/solid-pseudopapillary-neoplasm-of-the-pancreas
#34
JOURNAL ARTICLE
Jorge Roberto Marcante Carlotto, Franz Robert Apodaca Torrez, Adriano Miziara Gonzalez, Marcelo Moura Linhares, Tarcisio Triviño, Benedito Herani-Filho, Alberto Goldenberg, Gaspar de Jesus Lopes-Filho, Edson José Lobo
BACKGROUND: The solid pseudopapillary neoplasm is a rare tumor of the pancreas. However, it´s etiology still maintain discussions. AIM: To analyze it´s clinical data, diagnosis and treatment. METHODS: A retrospective study of medical records of all patients treated from January 1997 until July 2015. RESULTS: Were identified 17 cases. Most patients were women (94.11%) and the average age was 32.88 years. The main complaint was abdominal mass (47...
April 2016: Brazilian Archives of Digestive Surgery: ABCD
https://read.qxmd.com/read/26981042/management-of-infantile-blount-s-disease-with-molded-orthoses-a-new-perspective
#35
JOURNAL ARTICLE
Nei Botter Montenegro, Bruno Sergio Ferreira Massa, Luiz Renato Agrizzi de Angeli
OBJECTIVE: : This retrospective study evaluated treatment with individually contoured molded bracing at early stages of the disease. METHODS: : We evaluated the medical records of patients undergoing treatment of Blount's disease with molded orthoses for medial decompression between 2010 and 2014. The deformity angle (Drennan's metaphyseal-diaphyseal angle) and Langenskiöld classification were measured before and after treatment by a pediatric orthopedic surgeon with over 5 years of practice, blinded for the study and patients...
March 2016: Acta Ortopedica Brasileira
https://read.qxmd.com/read/25816082/combined-rigid-and-flexible-endoscopy-for-tumors-in-the-posterior-third-ventricle
#36
JOURNAL ARTICLE
Jonathan Roth, Shlomi Constantini
OBJECT: Tumors leading to occlusion of the sylvian aqueduct include those of pineal, thalamic, and tectal origins. These tumors cause obstructive hydrocephalus and thus necessitate a CSF diversion procedure such as an endoscopic third ventriculostomy (ETV), often coupled with an endoscopic biopsy (EBX). Lesions located posterior to the massa intermedia pose a technical challenge, as the use of a rigid endoscope for performing both an ETV and EBX is limited. The authors describe their experience using a combined rigid and flexible endoscopic procedure through a single bur hole for both procedures in patients with posterior third ventricular tumors...
June 2015: Journal of Neurosurgery
https://read.qxmd.com/read/25157990/one-step-mini-invasive-treatment-of-abdominal-aortic-iliac-aneurysm-associated-with-colo-rectal-cancer
#37
JOURNAL ARTICLE
Bruno Amato, Giovanni Esposito, Raffaele Serra, Rita Compagna, Gabriele Vigliotti, Tommaso Bianco, Guido Massa, Maurizio Amato, Salvatore Massa, Giovanni Aprea
BACKGROUND: Endovascular aneurysm repair (EVAR) is still now a controversial technique, which remains the subject of a number of prospective randomised trials. Although questions remain regarding its long-term durability, objective evidence exists which demonstrates its reduced physiological impact compared with conventional open repair, especially for older population and for the concomitant treatment of aortic abdominal aneurysm (AAA) and abdominal neoplas, such as colo-rectal cancer (CRC)...
2014: International Journal of Surgery
https://read.qxmd.com/read/25000975/nutritional-problems-in-children-with-neuromotor-disabilities-an-italian-case-series
#38
JOURNAL ARTICLE
Maria Sangermano, Roberta D'Aniello, Grazia Massa, Raffaele Albano, Pasquale Pisano, Mauro Budetta, Goffredo Scuccimarra, Enrico Papa, Giangennaro Coppola, Pietro Vajro
BACKGROUND AND AIMS: Several neuromotor disorders share exclusive, although often overlooked, nutritional problems. The objective of this study is therefore to delineate the frequency of malnutrition, evaluate the effectiveness of nutritional care, and identify issues needing to be possibly strengthened when caring for these patients into a general pediatrics department. PATIENTS AND METHODS: The study included 30 patients, 21 males and 9 females, aged between 2 and 15 years, affected by cerebral palsy, epileptic encephalopathy, and severe psychomotor developmental delay...
July 8, 2014: Italian Journal of Pediatrics
https://read.qxmd.com/read/24901680/acute-symptomatic-meckel-diverticulum-management-our-experience-on-seven-consecutive-cases
#39
JOURNAL ARTICLE
Umberto Robustelli, Francesco Manguso, Mariano Fortunato Armellino, Maria Pia Mannelli, Maria Rosaria Massa, Anna Lucia Forner, Roberto Bellotti, Francesco Ambrosino, Beatrice Ulloa Severino
Meckel's diverticulum (MD ) is the most common congenital anomaly of the gastrointestinal tract. We revalued clinical records of patients discharged from Unit of Urgent and General Surgery of Highly Specialized Hospital "A.O.R.N. Antonio Cardarelli" of Naples with diagnosis of acute pathology associated to complicated MD from 1(st) January 2011 to 30(th) November 2012. Seven consecutive cases have been chosen: five males (71,4%) and two females (28,6%). The age ranges over from 13 to 50 years with a 28 years average...
March 2014: Annali Italiani di Chirurgia
https://read.qxmd.com/read/24531177/romiplostim-for-severe-thrombocytopenia-in-the-treatment-of-chronic-hepatitis-c-virus-infection-a-new-option-for-clinicians
#40
JOURNAL ARTICLE
Giovanni Buccoliero, Tiziana Urbano, Patrizio Massa, Francesco Resta, Salvatore Pisconti
We describe a case of a 64-year-old man with a history of ITP which had required several treatments including splenectomy, and with chronic hepatitis C virus (HCV) infection untreated due to severe thrombocytopenia. In March 2011, platelet count was 14,000/mmc and a thrombopoietic therapy with romiplostim was initiated at the dose of 2 mcg/kg/week that was increased to 8 mcg/kg/week. At week 32, platelet count was 65,000/mmc and an anti-HCV therapy with peginterferon and ribavirin was then started. At baseline laboratory tests indicated AST 99IU/l, ALT 125UI/l, HCV_RNA 3,220 UI/ml and HCV genotype 2a/2c...
January 2014: New Microbiologica
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