David G Gelikman, Esther Mena, Liza Lindenberg, William S Azar, Nityam Rathi, Enis C Yilmaz, Stephanie A Harmon, Kyle C Schuppe, Jessica Y Hsueh, Hannah Huth, Bradford J Wood, Sandeep Gurram, Peter L Choyke, Peter A Pinto, Baris Turkbey
PURPOSE: Prostate-specific membrane antigen (PSMA)-targeting PET radiotracers reveal physiologic uptake in the urinary system, potentially misrepresenting activity in the prostatic urethra as an intraprostatic lesion. This study examined the correlation between midline 18F-DCFPyL activity in the prostate and hyperintensity on T2-weighted (T2W) MRI as an indication of retained urine in the prostatic urethra. PATIENTS AND METHODS: Eighty-five patients who underwent both 18F-DCFPyL PSMA PET/CT and prostate MRI between July 2017 and September 2023 were retrospectively analyzed for midline radiotracer activity and retained urine on postvoid T2W MRIs...
April 19, 2024: Clinical Nuclear Medicine