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https://www.readbyqxmd.com/read/27906526/statistical-learning-a-powerful-mechanism-that-operates-by-mere-exposure
#1
REVIEW
Richard N Aslin
How do infants learn so rapidly and with little apparent effort? In 1996, Saffran, Aslin, and Newport reported that 8-month-old human infants could learn the underlying temporal structure of a stream of speech syllables after only 2 min of passive listening. This demonstration of what was called statistical learning, involving no instruction, reinforcement, or feedback, led to dozens of confirmations of this powerful mechanism of implicit learning in a variety of modalities, domains, and species. These findings reveal that infants are not nearly as dependent on explicit forms of instruction as we might have assumed from studies of learning in which children or adults are taught facts such as math or problem solving skills...
December 1, 2016: Wiley Interdisciplinary Reviews. Cognitive Science
https://www.readbyqxmd.com/read/27906497/neuroembryology
#2
REVIEW
Diana Darnell, Scott F Gilbert
How is it that some cells become neurons? And how is it that neurons become organized in the spinal cord and brain to allow us to walk and talk, to see, recall events in our lives, feel pain, keep our balance, and think? The cells that are specified to form the brain and spinal cord are originally located on the outside surface of the embryo. They loop inward to form the neural tube in a process called neurulation. Structures that are nearby send signals to the posterior neural tube to form and pattern the spinal cord so that the dorsal side receives sensory input and the ventral side sends motor signals from neurons to muscles...
December 1, 2016: Wiley Interdisciplinary Reviews. Developmental Biology
https://www.readbyqxmd.com/read/27906437/vitamin-d-receptor-polymorphisms-as-tool-for-early-screening-of-severe-bone-loss-in-women-patients-with-rheumatoid-arthritis
#3
G Di Spigna, A Del Puente, B Covelli, E Abete, E Varriale, S Salzano, L Postiglione
OBJECTIVE: Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease that leads to local and systemic arthritis and bone loss. Exploring genetic markers of candidate genes in osteoporosis and inflammatory cytokine genes could be a useful tool for the early identification of bone loss and fracture risk in RA patients. The target of this study is the evaluation and correlation between of Single Nucleotide Polymorphisms (SNPs) of Vitamin D Receptor (VDR) and possible effects on bone loss in RA...
November 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27906276/muscowert-multi-scale-consistence-of-weighted-edge-radon-transform-for-horizon-detection-in-maritime-images
#4
Dilip K Prasad, Deepu Rajan, Lily Rachmawati, Eshan Rajabally, Chai Quek
This paper addresses the problem of horizon detection, a fundamental process in numerous object detection algorithms, in a maritime environment. The maritime environment is characterized by the absence of fixed features, the presence of numerous linear features in dynamically changing objects and background and constantly varying illumination, rendering the typically simple problem of detecting the horizon a challenging one. We present a novel method called multi-scale consistence of weighted edge Radon transform, abbreviated as MuSCoWERT...
December 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27906266/a-population-based-approach-to-point-sampling-spatial-color-algorithms
#5
Gabriele Gianini, Michela Lecca, Alessandro Rizzi
Inspired by the behavior of the human visual system, spatial color algorithms perform image enhancement by correcting the pixel channel lightness based on the spatial distribution of the intensities in the surrounding area. The two visual contrast enhancement algorithms RSR and STRESS belong to this family of models: they rescale the input based on local reference values, which are determined by exploring the image by means of random point samples, called sprays. Due to the use of sampling, they may yield a noisy output...
December 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27906229/aperture-coded-confocal-profilometry
#6
Jaka Pribošek, Janez Diaci, Stefan Sinzinger
This Letter introduces a novel principle to the confocal profilometry for simultaneous measurement of surface position and tilt. The principle relies on an angle-dependent coding of the illumination of the surface-under-test, achieved by dividing the pupil into several subapertures. The reflected light is decoded to perform an angle-resolved analysis by measuring the intensity contributions of each individual subaperture. By comparing their contributions, additional information of surface tilt can be inferred...
December 1, 2016: Optics Letters
https://www.readbyqxmd.com/read/27906224/analysis-of-sinusoidally-modulated-chirped-laser-pulses-by-temporally-encoded-spectral-shifting
#7
N H Matlis, A Maksimchuk, V Yanovsky, W P Leemans, M C Downer
We present an analytical formalism elucidating how information is stored in chirped optical probes by describing the effects of sinusoidal temporal modulations on the electric field. We show that the modulations produce spectral sidebands which can be interpreted as temporal sidebands due to the time-wavelength mapping, an effect we call temporally encoded spectral shifting (TESS). A derivation is presented for the case of chirped-pulse spectral interferometry showing how to recover both the amplitude and the periodicity of the modulation from a Fourier transform of the interferogram...
December 1, 2016: Optics Letters
https://www.readbyqxmd.com/read/27906120/one-health-training-research-and-outreach-in-north-america
#8
REVIEW
Cheryl Stroud, Bruce Kaplan, Jenae E Logan, Gregory C Gray
BACKGROUND: The One Health (OH) concept, formerly referred to as 'One Medicine' in the later part of the 20th century, has gained exceptional popularity in the early 21st century, and numerous academic and non-academic institutions have developed One Health programs. OBJECTIVES: To summarize One Health training, research, and outreach activities originating in North America. METHODS: We used data from extensive electronic records maintained by the One Health Commission (OHC) (www...
2016: Infection Ecology & Epidemiology
https://www.readbyqxmd.com/read/27905974/dynamic-denominators-the-impact-of-seasonally-varying-population-numbers-on-disease-incidence-estimates
#9
Elisabeth Zu Erbach-Schoenberg, Victor A Alegana, Alessandro Sorichetta, Catherine Linard, Christoper Lourenço, Nick W Ruktanonchai, Bonita Graupe, Tomas J Bird, Carla Pezzulo, Amy Wesolowski, Andrew J Tatem
BACKGROUND: Reliable health metrics are crucial for accurately assessing disease burden and planning interventions. Many health indicators are measured through passive surveillance systems and are reliant on accurate estimates of denominators to transform case counts into incidence measures. These denominator estimates generally come from national censuses and use large area growth rates to estimate annual changes. Typically, they do not account for any seasonal fluctuations and thus assume a static denominator population...
October 12, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905971/trends-causes-and-risk-factors-of-mortality-among-children-under-5-in-ethiopia-1990-2013-findings-from-the-global-burden-of-disease-study-2013
#10
Amare Deribew, Gizachew Assefa Tessema, Kebede Deribe, Yohannes Adama Melaku, Yihunie Lakew, Azmeraw T Amare, Semaw F Abera, Mesoud Mohammed, Abiy Hiruye, Efrem Teklay, Awoke Misganaw, Nicholas Kassebaum
BACKGROUND: Ethiopia has made remarkable progress in reducing child mortality over the last two decades. However, the under-5 mortality rate in Ethiopia is still higher than the under-5 mortality rates of several low- and middle-income countries (LMIC). On the other hand, the patterns and causes of child mortality have not been well investigated in Ethiopia. The objective of this study was to investigate the mortality trend, causes of death, and risk factors among children under 5 in Ethiopia during 1990-2013...
November 14, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905970/a-feasibility-study-on-using-smartphones-to-conduct-short-version-verbal-autopsies-in-rural-china
#11
Jing Zhang, Rohina Joshi, Jixin Sun, Samantha R Rosenthal, Miao Tong, Cong Li, Rasika Rampatige, Meghan Mooney, Alan Lopez, Lijing L Yan
BACKGROUND: Currently there are two main sources of mortality data with cause of death assignments in China. Both sources-the Ministry of Health-Vital Registration system and the Chinese Disease Surveillance Point system-present their own challenges. A new approach to cause of death assignment is a smartphone-based shortened version of a verbal autopsy survey. This study evaluates the feasibility and acceptability of this new method conducted by township health care providers (THP) and village doctors (VD) in rural China, where a large proportion of deaths occur in homes and cause of death data are inaccurate or lacking...
August 20, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905958/choosing-an-epidemiological-model-structure-for-the-economic-evaluation-of-non-communicable-disease-public-health-interventions
#12
Adam D M Briggs, Jane Wolstenholme, Tony Blakely, Peter Scarborough
Non-communicable diseases are the leading global causes of mortality and morbidity. Growing pressures on health services and on social care have led to increasing calls for a greater emphasis to be placed on prevention. In order for decisionmakers to make informed judgements about how to best spend finite public health resources, they must be able to quantify the anticipated costs, benefits, and opportunity costs of each prevention option available. This review presents a taxonomy of epidemiological model structures and applies it to the economic evaluation of public health interventions for non-communicable diseases...
May 4, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905920/synergistic-effects-and-related-bioactive-mechanism-of-potentilla-fruticosa-l-leaves-combined-with-ginkgo-biloba-extracts-studied-with-microbial-test-system-mts
#13
Ze-Hua Liu, Dong-Mei Wang, Su-Fang Fan, Deng-Wu Li, Zi-Wen Luo
BACKGROUND: Potentilla fruticosa, also called "Jinlaomei" and "Gesanghua", is widely used as folk herbs in traditional Tibetan medicine in China to treat inflammations, wounds, certain forms of cancer, diarrhoea, diabetes and other ailments. Previous research found P. fruticosa leaf extract (C-3) combined with Ginkgo biloba extracts (EGb) showed obvious synergistic effects in a variety of oxidation systems. The aim of the present study was to further confirm the synergy of P. fruticosa combined with EGb viewed from physiological bioavailability and explore the related bioactive mechanism behind the synergism...
December 1, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27905815/medicare-program-merit-based-incentive-payment-system-mips-and-alternative-payment-model-apm-incentive-under-the-physician-fee-schedule-and-criteria-for-physician-focused-payment-models-final-rule-with-comment-period
#14
(no author information available yet)
The Medicare Access and CHIP Reauthorization Act of 2015 (MACRA) repeals the Medicare sustainable growth rate (SGR) methodology for updates to the physician fee schedule (PFS) and replaces it with a new approach to payment called the Quality Payment Program that rewards the delivery of high-quality patient care through two avenues: Advanced Alternative Payment Models (Advanced APMs) and the Merit-based Incentive Payment System (MIPS) for eligible clinicians or groups under the PFS. This final rule with comment period establishes incentives for participation in certain alternative payment models (APMs) and includes the criteria for use by the Physician-Focused Payment Model Technical Advisory Committee (PTAC) in making comments and recommendations on physician-focused payment models (PFPMs)...
November 4, 2016: Federal Register
https://www.readbyqxmd.com/read/27905628/-virulence-mechanisms-of-enteropathogenic-escherichia-coli
#15
Ana Elvira Farfán-García, Sandra Catherine Ariza-Rojas, Fabiola Andrea Vargas-Cárdenas, Lizeth Viviana Vargas-Remolina
Acute diarrheal disease (ADD) is a global public health problem, especially in developing countries and is one of the causes of mortality in children under five. ADD etiologic agents include viruses, bacteria and parasites in that order. Escherichia coli bacteria it is classified as a major diarrheagenic agent and transmitted by consuming contaminated water or undercooked foods. This review compiled updates on information virulence factors and pathogenic mechanisms involved in adhesion and colonization of seven pathotypes of E...
August 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/27905608/drop-coating-deposition-of-a-liposome-suspension-on-surfaces-with-different-wettabilities-coffee-ring-formation-and-suspension-preconcentration
#16
Eva Kočišová, Martin Petr, Hana Šípová, Ondřej Kylián, Marek Procházka
Evaporation of a drop of biomolecular solution on a solid surface typically creates a ring-shaped drying pattern, formed by the so-called "coffee ring" effect. The size and shape of the "coffee ring" pattern is strongly dependent on the properties of the surface as well as on the deposited molecular solution or suspension. In this paper, we tested six types of surfaces differing in their physico-chemical surface characteristics (contact angles, wettability and roughness) as well as in the presence or absence of a base metal layer...
December 1, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27904986/a-qualitative-study-of-clinicians-experience-with-rating-of-the-global-assessment-of-functioning-gaf-scale
#17
I H Monrad Aas, Ove Sonesson, Steffen Torp
The severity of illness in psychiatry is rated using the Global Assessment of Functioning (GAF) scale. The GAF scale is often used in both research settings and in the clinic. The scale ranges from 1 to 100 and is subdivided into ten 10-point intervals, each with verbal rating instructions called anchor points and examples. GAF is an instrument that needs improvement. Studying clinicians' experiences with this rating system may be important for developing improvements. The aim of this study was to collect information from clinicians about their experiences with the GAF instrument, and to collect their ideas on how the GAF scale can be improved, particularly in the area of verbal instructions (i...
November 30, 2016: Community Mental Health Journal
https://www.readbyqxmd.com/read/27904961/muscle-elastography-a-new-imaging-technique-for-multiple-sclerosis-spasticity-measurement
#18
G Illomei, G Spinicci, E Locci, M G Marrosu
Multiple sclerosis (MS) spasticity is currently evaluated on the basis of neurological examinations such as Ashworth Scale (AS) and 0-10 NRS. Severity of spasticity is difficult to quantify. We investigated the use of real time elastography (RTHE) ultrasounds for evaluating objectively the muscle fibers status in MS spasticity patients and their changes after a new antispasticity treatment. Two studies were performed. In study A, 110 MS patients underwent a neurological evaluation based on the AS and RTHE. The RTHE images were scored with the new 1-5 muscle fibers rigidity imaging scale, here called MEMSs (Muscle Elastography Multiple Sclerosis Score)...
November 30, 2016: Neurological Sciences
https://www.readbyqxmd.com/read/27904960/active-and-passive-involvement-of-claudins-in-the-pathophysiology-of-intestinal-inflammatory-diseases
#19
REVIEW
Christian Barmeyer, Michael Fromm, Jörg-Dieter Schulzke
Intestinal inflammatory diseases, four of which are discussed here, are associated with alterations of claudins. In ulcerative colitis, diarrhea and antigen entry into the mucosa occurs. Claudin-2 is upregulated but data on other claudins are still limited or vary (e.g., claudin-1 and -4). Apart from that, tight junction changes contribute to diarrhea via a leak flux mechanism, while protection against antigen entry disappears behind epithelial gross lesions (erosions) and apoptotic foci. Crohn's disease is additionally characterized by a claudin-5 and claudin-8 reduction which plays an active role in antigen uptake already before gross lesions appear...
November 30, 2016: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/27904954/the-mathematics-of-xenology-di-cographs-symbolic-ultrametrics-2-structures-and-tree-representable-systems-of-binary-relations
#20
Marc Hellmuth, Peter F Stadler, Nicolas Wieseke
The concepts of orthology, paralogy, and xenology play a key role in molecular evolution. Orthology and paralogy distinguish whether a pair of genes originated by speciation or duplication. The corresponding binary relations on a set of genes form complementary cographs. Allowing more than two types of ancestral event types leads to symmetric symbolic ultrametrics. Horizontal gene transfer, which leads to xenologous gene pairs, however, is inherent asymmetric since one offspring copy "jumps" into another genome, while the other continues to be inherited vertically...
November 30, 2016: Journal of Mathematical Biology
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