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https://www.readbyqxmd.com/read/28526632/erythrocytosis-following-testosterone-therapy
#1
REVIEW
Samuel J Ohlander, Bibin Varghese, Alexander W Pastuszak
INTRODUCTION: A rapid increase in awareness of androgen deficiency has led to substantial increases in prescribing of testosterone therapy (TTh), with benefits of improvements in mood, libido, bone density, muscle mass, body composition, energy, and cognition. However, TTh can be limited by its side effects, particularly erythrocytosis. This review examines the literature on testosterone-induced erythrocytosis and polycythemia. AIM: To review the available literature on testosterone-induced erythrocytosis, discuss possible mechanisms for pathophysiology, determine the significance of formulation, and elucidate potential thromboembolic risk...
May 16, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28514618/aerobic-or-resistance-exercise-or-both-in-dieting-obese-older-adults
#2
RANDOMIZED CONTROLLED TRIAL
Dennis T Villareal, Lina Aguirre, A Burke Gurney, Debra L Waters, David R Sinacore, Elizabeth Colombo, Reina Armamento-Villareal, Clifford Qualls
BACKGROUND: Obesity causes frailty in older adults; however, weight loss might accelerate age-related loss of muscle and bone mass and resultant sarcopenia and osteopenia. METHODS: In this clinical trial involving 160 obese older adults, we evaluated the effectiveness of several exercise modes in reversing frailty and preventing reduction in muscle and bone mass induced by weight loss. Participants were randomly assigned to a weight-management program plus one of three exercise programs - aerobic training, resistance training, or combined aerobic and resistance training - or to a control group (no weight-management or exercise program)...
May 18, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28481907/relationship-between-anthropometric-parameters-and-open-angle-glaucoma-the-korea-national-health-and-nutrition-examination-survey
#3
Jae Yeun Lee, Tae-Woo Kim, Hyun Tae Kim, Mi Yeon Lee, Hye Won Min, Yu Sam Won, Hyun Seok Kwon, Ki Ho Park, Joon Mo Kim
AIMS: To evaluate the relationships between open-angle glaucoma (OAG) and various anthropometric measurements. DESIGN: Korea National Health and Nutrition Examination Survey (KNHANES), a population-based cross-sectional study using a complex, stratified, multistage, probability-cluster survey. METHODS: A total of 5,255 participants including 247 glaucoma patients, aged ≥ 19 years were included from the KNHANES V database. Glaucoma diagnosis was based on International Society of Geographical and Epidemiological Ophthalmology criteria...
2017: PloS One
https://www.readbyqxmd.com/read/28475119/oral-treatment-with-the-ghrelin-receptor-agonist-hm01-attenuates-cachexia-in-mice-bearing-colon-26-c26-tumors
#4
Fabienne O Villars, Claudio Pietra, Claudio Giuliano, Thomas A Lutz, Thomas Riediger
The gastrointestinal hormone ghrelin reduces energy expenditure and stimulates food intake. Ghrelin analogs are a possible treatment against cancer anorexia-cachexia syndrome (CACS). This study aimed to investigate whether oral treatment with the non-peptidergic ghrelin receptor agonist HM01 counteracts CACS in colon-26 (C26) tumor-bearing mice. The C26 tumor model is characterized by pronounced body weight (BW) loss and muscle wasting in the absence of severe anorexia. We analyzed the time course of BW loss, body composition, muscle mass, bone mineral density, and the cytokines interleukin-6 (IL-6) and macrophage-inhibitory cytokine-1 (MIC-1)...
May 5, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28465219/differences-in-body-composition-according-to-gross-motor-function-in-children-with-cerebral-palsy
#5
Ki Hyuk Sung, Chin Youb Chung, Kyoung Min Lee, Byung Chae Cho, Seung Jun Moon, Jaeyoung Kim, Moon Seok Park
OBJECTIVES: To assess differences in body composition according to gross motor function in children with cerebral palsy (CP) compared to healthy controls. DESIGN: Retrospective case control study. SETTING: Tertiary referral center for CP PARTICIPANTS: One hundred consecutive patients (mean age, 11.5 ± 4.2 years) with CP who were admitted for orthopedic surgery between May 2014 and March 2016 and 46 typically developing children (TDC, control group) were included...
April 29, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28448364/deep-tissue-pressure-injury-a-clinical-review
#6
Ave Preston, Aditi Rao, Robyn Strauss, Rebecca Stamm, Demetra Zalman
: A deep tissue pressure injury (DTPI) is a serious type of pressure injury that begins in the muscle closest to the bone and may not be visible in its early stages. Its hallmark is rapid deterioration despite the use of appropriate preventive interventions. In 2007, the National Pressure Ulcer Advisory Panel added suspected deep tissue injuries to the traditional classification system, and by 2010 DTPIs had accounted for about 9% of all pressure injuries and were for the first time more prevalent than stage 3 or 4 pressure injuries...
May 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28442780/the-effect-of-body-composition-and-serum-inflammatory-markers-on-the-functional-muscle-bone-unit-in-premenopausal-women
#7
S M Mueller, I Herter-Aeberli, A C Cepeda-Lopez, M Flück, H H Jung, M Toigo
BACKGROUND/OBJECTIVES: A number of recent studies dealing with the relationship between the effects of high body mass (BM) and fat mass (FM) on bone mass and strength exhibit a range of contrasting variations in their findings. These diverse findings have led to an ongoing controversy as to whether high BM and FM positively or negatively affect bone mass and strength. Excessive fat mass and the associated low-grade inflammation might overturn the higher mechanical stimulus arising from a higher body mass...
April 26, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28442508/aging-human-body-changes-in-bone-muscle-and-body-fat-with-consequent-changes-in-nutrient-intake
#8
Pegah JafariNasabian, Julia E Inglis, Wendimere Reilly, Owen J Kelly, Jasminka Z Ilich
Aging affects almost all physiological processes, but changes in body composition and body phenotype are most observable. In this review, we focus on these changes, including loss of bone and muscle and increase in body fat or redistribution of the latter, possibly leading to osteosarcopenic obesity syndrome. We also address low-grade chronic inflammation, prevalent in aging adults and a cause of many disorders including those associated with body composition. Changes in dietary intake and nutritional requirements of older individuals, that all may lead to some disturbances on tissue and organ levels, are discussed as well...
April 25, 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/28410328/manipulation-of-muscle-creatine-and-glycogen-changes-dual-x-ray-absorptiometry-estimates-of-body-composition
#9
Julia L Bone, Megan L Ross, Kristyen A Tomcik, Nikki A Jeacocke, Will G Hopkins, Louise M Burke
Standardizing a dual x-ray absorptiometry (DXA) protocol is thought to provide a reliable measurement of body composition. PURPOSE: We investigated the effects of manipulating muscle glycogen and creatine content independently and additively on DXA estimates of lean mass. METHOD: Eighteen well-trained male cyclists undertook a parallel group application of creatine loading (n = 9) (20 g·d for 5 d loading; 3 g·d maintenance) or placebo (n = 9) with crossover application of glycogen loading (12 v 6 g·kg BM per day for 48 h) as part of a larger study involving a glycogen-depleting exercise protocol...
May 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28394825/body-composition-assessment-in-the-prediction-of-osteoporotic-fractures
#10
Mélany Hars, Andrea Trombetti
PURPOSE OF REVIEW: To give an overview of recent research findings and insights on the role of body composition assessment in fracture risk prediction. RECENT FINDINGS: While there is to date little doubt that bone mineral density (BMD) is a main pathogenic factor of osteoporotic fractures, recent studies have emphasized the independent contribution of body composition components, especially lean mass, to fracture risk. In this article, we address body composition changes with aging, before to focus on recent studies addressing the contribution of lean and fat mass to fracture risk, together with some hypothesized mechanisms and clinical implications...
April 7, 2017: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/28351218/association-among-serum-insulin-like-growth-factor-1-frailty-muscle-mass-bone-mineral-density-and-physical-performance-among-community-dwelling-middle-aged-and-older-adults-in-taiwan
#11
Liang-Yu Chen, Yi-Hui Wu, Li-Kuo Liu, Wei-Ju Lee, An-Chun Hwang, Li-Ning Peng, Ming-Hsien Lin, Liang-Kung Chen
Aging is featured by the complex interrelationship among body composition, frailty status, and physical performance. The main aim of this study was to evaluate the association among serum insulin-like growth factor-1 (IGF-1), body composition, and physical function among community-dwelling middle-aged and elderly population in Taiwan. We conducted a cross-sectional study by using the data of I-Lan Longitudinal Aging Study, which recruited a total of 1833 community-dwelling people aged more than 50 years. Data of lean body mass (LBM), appendicular skeletal muscle mass (ASM), total fat mass (TFM), bone mineral density (BMD) of L-spine/hip, handgrip strength, walking speed, International Physical Activity Questionnaire (IPAQ), Charlson comorbidity index (CCI), serum levels of growth hormone, IGF-1, albumin, total cholesterol, triglyceride, blood urea nitrogen, and creatinine were retrieved for analysis...
May 9, 2017: Rejuvenation Research
https://www.readbyqxmd.com/read/28331906/associations-between-sarcopenia-and-degenerative-lumbar-scoliosis-in-older-women
#12
Yawara Eguchi, Munetaka Suzuki, Hajime Yamanaka, Hiroshi Tamai, Tatsuya Kobayashi, Sumihisa Orita, Kazuyo Yamauchi, Miyako Suzuki, Kazuhide Inage, Kazuki Fujimoto, Hirohito Kanamoto, Koki Abe, Yasuchika Aoki, Tomoaki Toyone, Tomoyuki Ozawa, Kazuhisa Takahashi, Seiji Ohtori
BACKGROUND: Age-related sarcopenia can cause various forms of physical disabilities. We investigated how sarcopenia affects degenerative lumbar scoliosis (DLS) and lumbar spinal canal stenosis (LSCS). METHODS: Subjects comprised 40 elderly women (mean age 74 years) with spinal disease whose chief complaints were low back pain and lower limb pain. They included 15 cases of DLS (mean 74.8 years) and 25 cases of LSCS (mean age 72.9 years). We performed whole-body dual-energy X-ray absorptiometry (DXA) to analyze body composition, including appendicular and trunk skeletal muscle mass index (SMI; lean mass (kg)/height (m)(2)) and bone mineral density (BMD)...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28331805/prevotella-osteomyelitis-after-dental-capping-procedure
#13
Alexander Williams, Thomas Kerkering
We present a 49 year old man who presented to the emergency department with severe lower back pain of 5 days duration. One week prior he had been diagnosed with a right psoas muscle abscess and was discharged with a 28 day course of moxifloxacin after the preliminary culture from the psoas grew an anaerobic organism. MRI of the lumbar spine showed marrow edema in the L2 body, occupying most of the anterior two thirds of the body, with cortical erosion at the anteroinferior aspect of L1. Blood cultures were negative and bone biopsy of L2 showed neutrophilic invasion and reactive changes...
2017: IDCases
https://www.readbyqxmd.com/read/28285470/the-effect-of-a-muscle-weight-bearing-and-aerobic-exercise-program-on-the-body-composition-muscular-strength-biochemical-markers-and-bone-mass-of-obese-patients-who-have-undergone-gastric-bypass-surgery
#14
Luciana Campanha-Versiani, Danielle Aparecida Gomes Pereira, Giane Amorim Ribeiro-Samora, Adauto Versiani Ramos, Maria Fatima H de Sander Diniz, Luiz Armando De Marco, Maria Marta Sarquis Soares
BACKGROUND: The effect of an exercise program on the body composition, muscular strength (MS), biochemical markers, and bone mineral density (BMD) of individuals undergoing gastric bypass is unclear. We assessed lean mass (LM), MS, bone remodeling markers, and BMD before and after supervised weight-bearing and aerobic exercise training in obese patients who underwent Roux-en-Y gastric bypass (RYGB). METHODS: This study included 37 obese patients (81.1% women, mean age 38...
March 11, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28284666/anthropometric-and-biomechanical-characteristics-of-body-segments-in-persons-with-spinal-cord-injury
#15
Y Fang, L R Morse, N Nguyen, N G Tsantes, K L Troy
People with spinal cord injury (SCI) experience bone and muscle loss in their paralyzed limbs that is most rapid and severe in the first 3years after injury. Restoration of mechanical loading through therapeutic physical activity may potentially slow or reverse post-SCI bone loss, however, therapeutic targets cannot be developed without accurate biomechanical models. Obesity is prevalent among SCI population, and it alters body composition and further affects parameters of these models. Here, clinical whole body dual-energy X-ray absorptiometry data from people with acute (n=39) and chronic (n=61) SCI were analyzed to obtain anthropometric parameters including segment masses, center of mass location, and radius of gyration for both obese and non-obese individuals...
April 11, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28271457/insulin-growth-factor-1-correlates-with-higher-bone-mineral-density-and-lower-inflammation-status-in-obese-adult-subjects
#16
Rachele Fornari, Chiara Marocco, Davide Francomano, Simona Fittipaldi, Carla Lubrano, Viviana M Bimonte, Lorenzo M Donini, Emanuele Nicolai, Antonio Aversa, Andrea Lenzi, Emanuela A Greco, Silvia Migliaccio
PURPOSE: Obesity is a severe public health problem worldwide, leading to an insulin-resistant state in liver, adipose, and muscle tissue, representing a risk factor for type 2 diabetes mellitus, cardiovascular diseases, and cancer. We have shown that abdominal obesity is associated with homeostasis derangement, linked to several hormonal and paracrine factors. Data regarding potential link between GH/IGF1 axis, bone mineral density, and inflammation in obesity are lacking. Thus, aim of this study was to evaluate correlation among IGF-1, BMD, and inflammation in obese individuals...
March 7, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28244782/morphological-characteristics-of-street-workout-practitioners
#17
Javier Sanchez-Martinez, Paula Plaza, Alberto Araneda, Patricio Sánchez, Atilio Almagiâ
INTRODUCTION: The determination of the morphological characteristics of the most popular sports has allowed the evaluation and comparison between athletes, which has helped to improve their performance. The Street Workout is an emerging sport based on calisthenics, which recently has become popular. Despite its popularization, neither the morphologic profile nor the morphologic characteristics of Street Workout athletes has been determined. OBJECTIVE: Determine the profile and morphological characteristics of Street-Workout athletes, through anthropometry...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28204901/the-effect-of-hydration-status-on-the-measurement-of-lean-tissue-mass-by-dual-energy-x-ray-absorptiometry
#18
Clodagh M Toomey, William G McCormack, Phil Jakeman
PURPOSE: Athletes cycle between exercise and recovery. Exercise invokes changes in total body water from thermal sweating, muscle and hepatic glycogen depletion and metabolic water loss. Recovery from exercise results in rehydration, substrate repletion, and possible glycogen supercompensation. Such changes may corrupt the measurement of hydrated tissues, such as lean tissue mass (LTM), by dual-energy X-ray absorptiometry (DXA). The purpose of this study was to determine the effect of exercise and thermal dehydration and subsequent glycogen supercompensation on DXA-based measurement of body composition...
March 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28151909/incidence-and-risk-factors-of-adjacent-segment-disease-following-posterior-decompression-and-instrumented-fusion-for-degenerative-lumbar-disorders
#19
Hui Wang, Lei Ma, Dalong Yang, Tao Wang, Sen Liu, Sidong Yang, Wenyuan Ding
The purpose of this study was to explore incidence and risk factors of adjacent segment disease (ASD) following posterior decompression and instrumented fusion for degenerative lumbar disorders, and hope to provide references in decision making and surgical planning for both spinal surgeon and surgically treated patients.By retrieving the medical records from January 2011 to December 2013 in our hospital, 237 patients were retrospectively reviewed. According to the occurrence of ASD at follow up, patients were divided into 2 groups: ASD and N-ASD group...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28148680/the-plasma-proteome-is-associated-with-anthropometric-status-of-undernourished-nepalese-school-aged-children
#20
Sun Eun Lee, Christine P Stewart, Kerry J Schulze, Robert N Cole, Lee S-F Wu, James D Yager, John D Groopman, Subarna K Khatry, Ramesh Kant Adhikari, Parul Christian, Keith P West
Background: Malnutrition affects body growth, size, and composition of children. Yet, few functional biomarkers are known to be associated with childhood morphology.Objective: This cross-sectional study examined associations of anthropometric indicators of height, musculature, and fat mass with plasma proteins by using proteomics in a population cohort of school-aged Nepalese children.Methods: Height, weight, midupper arm circumference (MUAC), triceps and subscapular skinfolds, upper arm muscle area (AMA), and arm fat area (AFA) were assessed in 500 children 6-8 y of age...
March 2017: Journal of Nutrition
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