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https://www.readbyqxmd.com/read/27607169/18f-fdg-pet-ct-imaging-of-cauda-equina-syndrome-secondary-to-leptomeningeal-metastatic-breast-cancer
#1
Lilja B Solnes, Mehrbod S Javadi, Steven P Rowe
Cauda equina syndrome (CES) is an uncommon entity that may be caused by a variety of conditions. It refers to dysfunction of the ventral, dorsal, sacral, and coccygeal nerve roots in the region of the filum terminale. We present a case of a 32-year-old woman with a history of BRCA1-positive metastatic breast cancer who complained of lower extremity muscle weakness increasing over a 2-week period and decreased sensation of the lower extremities accompanied by severe constipation and suspected urinary retention with overflow incontinence...
November 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27552842/relationships-between-mammographic-density-tissue-microvessel-density-and-breast-biopsy-diagnosis
#2
Ashley S Felix, Petra Lenz, Ruth M Pfeiffer, Stephen M Hewitt, Jennifer Morris, Deesha A Patel, Berta Geller, Pamela M Vacek, Donald L Weaver, Rachael E Chicoine, John Shepherd, Amir Pasha Mahmoudzadeh, Jeff Wang, Bo Fan, Serghei Malkov, Sally D Herschorn, Jason M Johnson, Renata L Cora, Louise A Brinton, Mark E Sherman, Gretchen L Gierach
BACKGROUND: Women with high levels of mammographic density (MD) have a four- to six-fold increased risk of developing breast cancer; however, most neither have a prevalent tumor nor will they develop one. Magnetic resonance imaging (MRI) studies suggest that background parenchymal enhancement, an indicator of vascularity, is related to increased breast cancer risk. Correlations of microvessel density (MVD) in tissue, MD and biopsy diagnosis have not been defined, and we investigated these relationships among 218 women referred for biopsy...
2016: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/27536906/prospective-comparison-of-whole-body-bone-spect-and-sodium-18f-fluoride-pet-in-the-detection-of-bone-metastases-from-breast-cancer
#3
Gad Abikhzer, Saher Srour, Georgeta Fried, Karen Drumea, Ela Kozlener, Alex Frenkel, Ora Israel, Ignac Fogelman, Olga Kagna
OBJECTIVE: The superiority of sodium F-fluoride PET (F-PET)/computed tomography (CT) over planar and single field-of-view single-photon emission computed tomography (SPECT) bone scintigraphy with Tc-methylene diphosphonate in bone metastases detection has been established. The present study prospectively compares whole-body Tc-methylene diphosphonate SPECT (WB-SPECT) and F-PET performance indices for the detection of bone metastases in breast cancer. METHODS: A total of 41 pairs of studies in female breast cancer patients (average age 58 years, range 30-75) were included...
November 2016: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/27501770/biochemical-and-imaging-surveillance-in-germline-tp53-mutation-carriers-with-li-fraumeni-syndrome-11-year-follow-up-of-a-prospective-observational-study
#4
Anita Villani, Ari Shore, Jonathan D Wasserman, Derek Stephens, Raymond H Kim, Harriet Druker, Bailey Gallinger, Anne Naumer, Wendy Kohlmann, Ana Novokmet, Uri Tabori, Marta Tijerin, Mary-Louise C Greer, Jonathan L Finlay, Joshua D Schiffman, David Malkin
BACKGROUND: Carriers of a germline TP53 pathogenic variant have a substantial lifetime risk of developing cancer. In 2011, we did a prospective observational study of members of families who chose to either undergo a comprehensive surveillance protocol for individuals with Li-Fraumeni syndrome or not. We sought to update our assessment of and modify the surveillance protocol, so in this study we report both longer follow-up of these patients and additional patients who underwent surveillance, as well as update the originally presented surveillance protocol...
September 2016: Lancet Oncology
https://www.readbyqxmd.com/read/27187730/assessment-of-aggressiveness-of-breast-cancer-using-simultaneous-18f-fdg-pet-and-dce-mri-preliminary-observation
#5
Nathaniel E Margolis, Linda Moy, Eric E Sigmund, Melanie Freed, Jason McKellop, Amy N Melsaether, Sungheon Gene Kim
PURPOSE: This study aims to investigate the feasibility of using simultaneous breast MRI and PET to assess the synergy of MR pharmacokinetic and fluorine-18 fluorodeoxyglucose (F-FDG) uptake data to characterize tumor aggressiveness in terms of metastatic burden and Ki67 status. METHODS: Twelve consecutive patients underwent breast and whole-body PET/MRI. During the MR scan, PET events were simultaneously accumulated. MR contrast kinetic model parametric maps were computed using the extended Tofts model, including the volume transfer constant between blood plasma and the interstitial space (K), the transfer constant from the interstitial space to the blood plasma (kep), and the plasmatic volume fraction (Vp)...
August 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27123931/inter-and-intra-observer-repeatability-of-quantitative-whole-body-diffusion-weighted-imaging-wbdwi-in-metastatic-bone-disease
#6
Matthew D Blackledge, Nina Tunariu, Matthew R Orton, Anwar R Padhani, David J Collins, Martin O Leach, Dow-Mu Koh
Quantitative whole-body diffusion-weighted MRI (WB-DWI) is now possible using semi-automatic segmentation techniques. The method enables whole-body estimates of global Apparent Diffusion Coefficient (gADC) and total Diffusion Volume (tDV), both of which have demonstrated considerable utility for assessing treatment response in patients with bone metastases from primary prostate and breast cancers. Here we investigate the agreement (inter-observer repeatability) between two radiologists in their definition of Volumes Of Interest (VOIs) and subsequent assessment of tDV and gADC on an exploratory patient cohort of nine...
2016: PloS One
https://www.readbyqxmd.com/read/27090254/32nd-international-austrian-winter-symposium-zell-am-see-the-netherlands-20-23-january-2016
#7
W Langsteger, A Rezaee, W Loidl, H S Geinitz, F Fitz, M Steinmair, G Broinger, L Pallwien-Prettner, M Beheshti, L Imamovic, M Beheshti, G Rendl, D Hackl, O Tsybrovsky, M Steinmair, K Emmanuel, F Moinfar, C Pirich, W Langsteger, A Bytyqi, G Karanikas, M Mayerhöfer, O Koperek, B Niederle, M Hartenbach, T Beyer, K Herrmann, J Czernin, I Rausch, P Rust, M D DiFranco, M Lassen, A Stadlbauer, M E Mayerhöfer, M Hartenbach, M Hacker, T Beyer, K Binzel, R Magnussen, W Wei, M U Knopp, D C Flanigan, C Kaeding, M V Knopp, A Leisser, M Nejabat, M Hartenbach, G Kramer, M Krainer, M Hacker, A Haug, Wencke Lehnert, Karl Schmidt, Sharok Kimiaei, Marcus Bronzel, Andreas Kluge, C L Wright, K Binzel, J Zhang, Evan Wuthrick, Piotr Maniawski, M V Knopp, M Blaickner, E Rados, A Huber, M Dulovits, H Kulkarni, S Wiessalla, C Schuchardt, R P Baum, B Knäusl, D Georg, M Bauer, B Wulkersdorfer, W Wadsak, C Philippe, H Haslacher, M Zeitlinger, O Langer, M Bauer, M Feldmann, R Karch, W Wadsak, M Zeitlinger, M J Koepp, M-C Asselin, E Pataraia, O Langer, M Zeilinger, C Philippe, M Dumanic, F Pichler, J Pilz, M Hacker, W Wadsak, M Mitterhauser, L Nics, B Steiner, M Hacker, M Mitterhauser, W Wadsak, A Traxl, Thomas Wanek, Kushtrim Kryeziu, Severin Mairinger, Johann Stanek, Walter Berger, Claudia Kuntner, Oliver Langer, S Mairinger, T Wanek, A Traxl, M Krohn, J Stanek, T Filip, M Sauberer, C Kuntner, J Pahnke, O Langer, D Svatunek, C Denk, M Wilkovitsch, T Wanek, T Filip, C Kuntner-Hannes, J Fröhlich, H Mikula, C Denk, D Svatunek, T Wanek, S Mairinger, J Stanek, T Filip, J Fröhlich, H Mikula, C Kuntner-Hannes, T Balber, J Singer, J Fazekas, C Rami-Mark, N Berroterán-Infante, E Jensen-Jarolim, W Wadsak, M Hacker, H Viernstein, M Mitterhauser, C Denk, D Svatunek, B Sohr, H Mikula, J Fröhlich, T Wanek, C Kuntner-Hannes, T Filip, S Pfaff, C Philippe, M Mitterhauser, M Hartenbach, M Hacker, W Wadsak, T Wanek, E Halilbasic, M Visentin, S Mairinger, B Stieger, C Kuntner, M Trauner, O Langer, P Lam, M Aistleitner, R Eichinger, C Artner, H Eidherr, C Vraka, A Haug, M Mitterhauser, L Nics, M Hartenbach, M Hacker, W Wadsak, H Kvaternik, R Müller, D Hausberger, C Zink, R M Aigner, U Cossío, M Asensio, A Montes, S Akhtar, Y Te Welscher, R van Nostrum, V Gómez-Vallejo, J Llop, F VandeVyver, T Barclay, N Lippens, M Troch, L Hehenwarter, B Egger, J Holzmannhofer, M Rodrigues-Radischat, C Pirich, N Pötsch, I Rausch, D Wilhelm, M Weber, J Furtner, G Karanikas, A Wöhrer, M Mitterhauser, M Hacker, T Traub-Weidinger, T Cassou-Mounat, S Balogova, V Nataf, M Calzada, V Huchet, K Kerrou, J-Y Devaux, M Mohty, L Garderet, J-N Talbot, S Stanzel, G Pregartner, T Schwarz, V Bjelic-Radisic, B Liegl-Atzwanger, R Aigner, S Stanzel, F Quehenberger, R M Aigner, A Koljević Marković, Milica Janković, V Miler Jerković, M Paskaš, G Pupić, R Džodić, D Popović, M C Fornito, D Familiari, P Koranda, H Polzerová, I Metelková, L Henzlová, R Formánek, E Buriánková, M Kamínek, W H Thomson, C Lewis, W H Thomson, J O'Brien, G James, A Notghi, H Huber, I Stelzmüller, R Wunn, M Mandl, F Fellner, B Lamprecht, M Gabriel, M C Fornito, G Leonardi, W H Thomson, J O'Brien, G James, J Hudzietzová, J Sabol, M Fülöp
A1 68Ga-PSMA PET/CT in staging and restaging of Prostate Cancer Patients: comparative study with 18F-Choline PET/CTW Langsteger, A Rezaee, W Loidl, HS Geinitz, F Fitz, M Steinmair, G Broinger, L Pallwien-Prettner, M BeheshtiA2 F18 Choline PET - CT: an accurate diagnostic tool for the detection of parathyroid adenoma?L Imamovic, M Beheshti, G Rendl, D Hackl, O Tsybrovsky, M Steinmair, K Emmanuel, F Moinfar, C Pirich, W LangstegerA3 [18F]Fluoro-DOPA-PET/CT in the primary diagnosis of medullary thyroid carcinomaA Bytyqi, G Karanikas, M Mayerhöfer, O Koperek, B Niederle, M HartenbachA4 Variations of clinical PET/MR operations: An international survey on the clinical utilization of PET/MRIT Beyer, K Herrmann, J CzerninA5 Standard Dixon-based attenuation correction in combined PET/MRI: Reproducibility and the possibility of Lean body mass estimationI Rausch, P Rust, MD DiFranco, M Lassen, A Stadlbauer, ME Mayerhöfer, M Hartenbach, M Hacker, T BeyerA6 High resolution digital FDG PET/MRI imaging for assessment of ACL graft viabilityK Binzel, R Magnussen, W Wei, MU Knopp, DC Flanigan, C Kaeding, MV KnoppA7 Using pre-existing hematotoxicity as predictor for severe side effects and number of treatment cycles of Xofigo therapyA Leisser, M Nejabat, M Hartenbach, G Kramer, M Krainer, M Hacker, A HaugA8 QDOSE - comprehensive software solution for internal dose assessmentWencke Lehnert, Karl Schmidt, Sharok Kimiaei, Marcus Bronzel, Andreas KlugeA9 Clinical impact of Time-of-Flight on next-generation digital PET imaging of Yttrium-90 radioactivity following liver radioembolizationCL Wright, K Binzel, J Zhang, Evan Wuthrick, Piotr Maniawski, MV KnoppA10 Snakes in patients! Lessons learned from programming active contours for automated organ segmentationM Blaickner, E Rados, A Huber, M Dulovits, H Kulkarni, S Wiessalla, C Schuchardt, RP Baum, B Knäusl, D GeorgA11 Influence of a genetic polymorphism on brain uptake of the dual ABCB1/ABCG2 substrate [11C]tariquidarM Bauer, B Wulkersdorfer, W Wadsak, C Philippe, H Haslacher, M Zeitlinger, O LangerA12 Outcome prediction of temporal lobe epilepsy surgery from P-glycoprotein activity...
April 2016: EJNMMI Research
https://www.readbyqxmd.com/read/26834098/imaging-bone-metastases-in-breast-cancer-staging-and-response-assessment
#8
REVIEW
Gary J R Cook, Gurdip K Azad, Vicky Goh
Bone metastases are common in patients with advanced breast cancer. Given the significant associated morbidity, the introduction of new, effective systemic therapies, and the improvement in survival time, early detection and response assessment of skeletal metastases have become even more important. Although planar bone scanning has recognized limitations, in particular, poor specificity in staging and response assessment, it continues to be the main method in current clinical practice for staging of the skeleton in patients at risk of bone metastases...
February 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/26797074/quantification-of-intra-fraction-motion-in-breast-radiotherapy-using-supine-magnetic-resonance-imaging
#9
Tristan C F van Heijst, Mariëlle E P Philippens, Ramona K Charaghvandi, Mariska D den Hartogh, Jan J W Lagendijk, H J G Desirée van den Bongard, Bram van Asselen
In early-stage breast-cancer patients, accelerated partial-breast irradiation techniques (APBI) and hypofractionation are increasingly implemented after breast-conserving surgery (BCS). For a safe and effective radiation therapy (RT), the influence of intra-fraction motion during dose delivery becomes more important as associated fraction durations increase and targets become smaller. Current image-guidance techniques are insufficient to characterize local target movement in high temporal and spatial resolution for extended durations...
February 7, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/26781152/evaluation-of-%C3%A2-%C3%A2-f-fdg-pet-mri-%C3%A2-%C3%A2-f-fdg-pet-ct-mri-and-ct-in-whole-body-staging-of-recurrent-breast-cancer
#10
Lino M Sawicki, Johannes Grueneisen, Benedikt M Schaarschmidt, Christian Buchbender, James Nagarajah, Lale Umutlu, Gerald Antoch, Sonja Kinner
OBJECTIVES: To compare the diagnostic performance of (18)F-fluordesoxyglucose positron emission tomography/magnetic resonance imaging ((18)F-FDG PET/MRI) with (18)F-FDG PET/computed tomography ((18)F-FDG PET/CT), MRI, and CT in whole-body staging of recurrent breast cancer. MATERIAL AND METHODS: Twenty-one consecutive patients (age 59.4 ± 11.5 years, range 38.5-76.9 years; 20 female, 1 male) with suspected breast cancer recurrence underwent a clinically indicated (18)F-FDG PET/CT and subsequently a (18)F-FDG PET/MRI examination in a single injection protocol (mean injected activity: 257 ± 44 MBq (18)F-FDG)...
February 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/26663655/diffusion-weighted-imaging-and-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-in-breast-cancer-correlation-of-the-apparent-diffusion-coefficient-and-maximum-standardized-uptake-values-with-prognostic-factors
#11
Belgin Karan, Aysin Pourbagher, Nese Torun
PURPOSE: To evaluate the correlations between the apparent diffusion coefficient (ADC) value and the standardized uptake value (SUV) with prognostic factors in breast cancer. MATERIALS AND METHODS: Seventy women with invasive breast cancer (56 cases of invasive ductal carcinoma, four of mixed ductal and lobular invasive carcinoma, three of lobular invasive carcinoma, two of micropapillary carcinoma, and one each of mixed ductal and mucinous carcinoma, mucinous carcinoma, medullary carcinoma, metaplastic carcinoma, and tubular carcinoma) were included in this study...
June 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/26405167/prospective-comparison-of-99mtc-mdp-scintigraphy-combined-18f-naf-and-18f-fdg-pet-ct-and-whole-body-mri-in-patients-with-breast-and-prostate-cancer
#12
COMPARATIVE STUDY
Ryogo Minamimoto, Andreas Loening, Mehran Jamali, Amir Barkhodari, Camila Mosci, Tatianie Jackson, Piotr Obara, Valentina Taviani, Sanjiv Sam Gambhir, Shreyas Vasanawala, Andrei Iagaru
UNLABELLED: We prospectively evaluated the use of combined (18)F-NaF/(18)F-FDG PET/CT in patients with breast and prostate cancer and compared the results with those for (99m)Tc-MDP bone scintigraphy and whole-body MRI. METHODS: Thirty patients (15 women with breast cancer and 15 men with prostate cancer) referred for standard-of-care bone scintigraphy were prospectively enrolled in this study. (18)F-NaF/(18)F-FDG PET/CT and whole-body MRI were performed after bone scintigraphy...
December 2015: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/26332194/correlation-of-tumor-characteristics-derived-from-dce-mri-and-dw-mri-with-histology-in-murine-models-of-breast-cancer
#13
COMPARATIVE STUDY
Stephanie L Barnes, Anna G Sorace, Mary E Loveless, Jennifer G Whisenant, Thomas E Yankeelov
The purpose of this work was to determine the relationship between the apparent diffusion coefficient (ADC, from diffusion-weighted (DW) MRI), the extravascular, extracellular volume fraction (ve , from dynamic contrast-enhanced (DCE) MRI), and histological measurement of the extracellular space fraction. Athymic nude mice were injected with either human epidermal growth factor receptor 2 positive (HER2+) BT474 (n = 15) or triple negative MDA-MB-231 (n = 20) breast cancer cells, treated with either Herceptin (n = 8), Abraxane (low dose n = 7, high dose n = 6), or saline (n = 7 for each cell line), and imaged using DW- and DCE-MRI before, during, and after treatment...
October 2015: NMR in Biomedicine
https://www.readbyqxmd.com/read/26319028/pattern-of-tumour-spread-of-common-primary-tumours-as-seen-on-magnetic-resonance-imaging
#14
David Laszlo Tarnoki, Adam Domonkos Tarnoki, Susanne Ohlmann-Knafo, Dirk Pickuth
Although some reports with computed tomography and bone scintigraphy are available in the literature, the distinct epidemiologic description of skeletal metastatic pattern of various tumors is still lacking. This study uses a novel approach to identify skeletal metastases from magnetic resonance imaging (MRI) data to describe metastatic pattern in common malignancies. A retrospective analysis of 130 cancer patients (42 lung, 56 breast, 11 prostate cancers; 21 multiple myeloma) with vertebral metastases and without disseminated disease, and whom underwent a whole body 3Tesla MRI investigation (Discovery MR750w), was carried out...
January 2016: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/26209689/urinary-incontinence-a-first-presentation-of-central-pontine-myelinolysis-a-case-report
#15
Asmah Hassan Syed, Joanna Shak, Ali Alsawaf
An 84-year-old lady was treated for hyperosmolar hyperglycaemia with IV insulin, fluids and catheterisation for fluid balance monitoring. Trial without catheter failed as the patient complained of new-onset urinary incontinence and lack of awareness of bladder filling. In light of her breast cancer history, we excluded cauda equina. Ultrasound KUB showed an enlarged bladder. Whole-body MRI revealed a lesion in the pons which was highly suggestive of central pontine myelinolysis (CPM). Her electrolytes were normal throughout her admission; thus, the rapid fluctuation in osmolality, secondary to her hyperglycaemic state, was the likely cause of CPM...
September 2015: Age and Ageing
https://www.readbyqxmd.com/read/26182970/multimodal-partial-volume-correction-application-to-18f-fluoride-pet-ct-bone-metastases-studies
#16
Elisabetta Grecchi, Jim O'Doherty, Mattia Veronese, Charalampos Tsoumpas, Gary J Cook, Federico E Turkheimer
UNLABELLED: (18)F-fluoride PET/CT offers the opportunity for accurate skeletal metastasis staging, compared with conventional imaging methods. (18)F-fluoride is a bone-specific tracer whose uptake depends on osteoblastic activity. Because of the resulting increase in bone mineralization and sclerosis, the osteoblastic process can also be detected morphologically in CT images. Although CT is characterized by high resolution, the potential of PET is limited by its lower spatial resolution and the resulting partial-volume effect...
September 2015: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/26050658/pet-mr-in-breast-cancer
#17
REVIEW
Claire Tabouret-Viaud, Diomidis Botsikas, Bénédicte M A Delattre, Ismini Mainta, Gaël Amzalag, Olivier Rager, Vincent Vinh-Hung, Raymond Miralbell, Osman Ratib
Breast cancer is an international public health concern in which an optimal treatment plan requires a precise staging. Both MRI and PET imaging techniques have made significant progress in the last decades with constant improvements that made both modalities clinically relevant in several stages of breast cancer management and follow-up. On one hand, specific breast MRI permits high diagnostic accuracy for local tumor staging, and whole-body MRI can also be of great use in distant staging, eventually accompanied by organ-specific MRI sequences...
July 2015: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/26049273/surveillance-recommendations-for-patients-with-germline-tp53-mutations
#18
REVIEW
Mandy L Ballinger, Gillian Mitchell, David M Thomas
PURPOSE OF REVIEW: Li-Fraumeni syndrome is associated with germline TP53 mutations and carriers have a high lifetime risk of cancer, the most common being sarcoma, breast cancer, brain tumors, adrenocortical carcinoma and leukemia. Germline TP53 mutation carriers are increasingly being identified as more genomic sequencing is performed in both clinical and research settings. There is a pressing clinical need for effective cancer risk management approaches in this group. RECENT FINDINGS: Current clinical surveillance guidelines mainly focus on breast and bowel cancer risk with little consideration for the other cancers common to the syndrome...
July 2015: Current Opinion in Oncology
https://www.readbyqxmd.com/read/26015806/sarcoidosis-with-bone-involvement-mimicking-metastatic-disease-at-18-f-fdg-pet-ct-problem-solving-by-diffusion-whole-body-mri
#19
REVIEW
Giorgio Conte, Fabio Zugni, Marco Colleoni, Giuseppe Renne, Massimo Bellomi, Giuseppe Petralia
Bone involvement has been reported in 1-13% of patients with sarcoidosis. Both 18F-fluorodeoxyglucose ((18)F-FDG) Positron Emission Tomography/Computed Tomography (PET/CT) and conventional magnetic resonance imaging (MRI) are sensitive in detecting sarcoidosis bone lesions, but are not always reliable in differentiating sarcoidosis bone lesions from metastatic disease, thus often requiring bone biopsy. We describe the use of diffusion whole-body MRI for bone assessment in a patient with breast cancer and sarcoidosis, presenting with bone marrow lesions mimicking metastatic disease at (18)F-FDG PET/CT...
2015: Ecancermedicalscience
https://www.readbyqxmd.com/read/25908171/manganese-oxide-and-docetaxel-co-loaded-fluorescent-polymer-nanoparticles-for-dual-modal-imaging-and-chemotherapy-of-breast-cancer
#20
Azhar Z Abbasi, Preethy Prasad, Ping Cai, Chunsheng He, Warren D Foltz, Mohammad Ali Amini, Claudia R Gordijo, Andrew M Rauth, Xiao Yu Wu
Multifunctional nanoparticles (NPs) have found important applications in diagnosis, chemotherapy, and image-guided surgery of tumors. In this work, we have developed polymeric theranostic NPs (PTNPs) containing the anticancer drug docetaxel (DTX), a fluorescent dye, and magnetic manganese oxide (MnO) NPs for dual modal imaging and chemotherapy. PTNPs ~150 nm in diameter were synthesized by co-loading hydrophobic DTX and MnO NPs ~5 nm in diameter, into the matrix of a fluorescent dye-labeled amphiphilic polymer...
July 10, 2015: Journal of Controlled Release: Official Journal of the Controlled Release Society
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