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https://www.readbyqxmd.com/read/28822555/influence-of-tumor-size-on-outcomes-following-pelvic-exenteration
#1
B Smith, E L Jones, M Kitano, A L Gleisner, N J Lyell, G Cheng, M D McCarter, S Abdel-Misih, F J Backes
OBJECTIVE: Pelvic exenteration (PE) is often the only curative option for locally advanced or recurrent pelvic malignancies. Despite radical surgery, recurrence risk and morbidity remain high. In this study, we sought to determine tumor size effect on perioperative outcomes and subsequent survival in patients undergoing PE. METHODS: Retrospective chart review was performed for female patients who underwent PE at two comprehensive cancer centers from 2000 to 2015...
August 16, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28820163/sympathetic-ophthalmia-related-to-conjunctival-invasive-squamous-cell-carcinoma
#2
In S Leal, David Cordeiro Sousa, Cláudia Loureiro, Ana Fonseca
Sympathetic ophthalmia (SO) is a rare, diffuse, bilateral, and granulomatous nonnecrotizing panuveitis that may follow intraocular penetrating trauma. Our aim is to report a rare case of SO following orbital exenteration. Orbital exenteration was performed on a 48-year-old african female due to conjunctival keratinizing squamous cell carcinoma with intraocular involvement of the left eye. Five days after the uneventful procedure, the patient presented signs and symptoms compatible with SO. Key differential diagnoses were excluded, and prompt and aggressive immunosuppression was started with a favourable but slow clinical response...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28812941/self-retaining-magnetic-implant-a-novel-design-of-orbital-prosthesis-for-the-exenterated-orbit
#3
Shiu Ting Mak, Timmy K C Chan, Kenneth K W Li
Orbital exenteration can lead to significant disfigurement causing considerable functional, cosmetic and psychological disturbances to the patient. Orbital prosthesis is important for the patient's cosmetic and psychological rehabilitation. A 49-year-old man received orbital exenteration and postoperative radiotherapy for malignant orbital carcinoma. In view of uncertain suitability and survival of osseointegrated implant in his case, a novel design of ocular implant consisting of a self-retaining magnetic spring retainer and a coupling silicone prosthesis was used...
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28812933/use-of-bilayer-matrix-wound-dressing-in-the-exenterated-socket
#4
Leon Rafailov, Roger E Turbin, Paul D Langer
To describe the novel use of a bilayer dermal substitute to reconstruct exenterated orbits. A retrospective chart review was performed in the practices of two surgeons (RET and PDL) of all patients who had undergone orbital exenteration between April 2014 and June 2016 and whose subsequent reconstruction included lining the socket with Integra bilayer. Patient demographics, pathologic diagnoses, surgical and post-operative complications, graft integrity, and patient acceptance were recorded. The charts of 7 patients (4 men and 3 women, ages 60-87 years) were reviewed...
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28812910/orbital-cancer-a-second-cancer-in-exenterated-patients
#5
Ebube E Obi, David Saunders, Joyce Burns, Ragavan Sampath
No abstract text is available yet for this article.
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28808931/robotic-total-pelvic-exenteration-video-illustrated-technique
#6
Ioannis T Konstantinidis, William Chu, Federico Tozzi, Clayton Lau, Mark Wakabayashi, Kevin Chan, Byrne Lee
BACKGROUND: Robotic-assisted total pelvic exenteration (TPE) can offer a minimally invasive approach to a major multi-organ operation. METHODS: In this video, we summarize a stepwise approach to robotic TPE in a 70 year-old female Jehovah's witness with a history of cervical cancer post-chemoradiation and radical hysterectomy who experienced local recurrence at the vaginal cuff involving the rectum and bladder. RESULTS: The patient was placed in the lithotomy position...
August 14, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28808913/modified-double-barrelled-wet-colostomy-after-total-pelvic-exenteration
#7
Antonio Macrì
Pelvic exenteration is a radical surgery that can require urinary and faecal diversions. Double-barreled wet colostomy, a viable alternative to the traditional ileal conduit with separate colostomy technique, is not always applicable due to the shortness of an ureter. To overcome this problem, I modified the original technique, replacing the two uretero-colic anastomoses with an ureteroureterostomy and an uretero-colic anastomosis.
August 14, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28752368/long-term-follow-up-of-conjunctival-melanoma-treated-with-topical-interferon-alpha-2b-eye-drops-as-adjunctive-therapy-following-surgical-resection
#8
Iku Kikuchi, Satoru Kase, Kan Ishijima, Susumu Ishida
PURPOSE: The purpose of this study was to report the clinical outcomes of patients with conjunctival melanoma treated with interferon (IFN) α-2b eye drops following local tumor resection. METHODS: Five eyes of five patients were enrolled in this study. All patients underwent the local resection of tumors, and topical IFNα-2b eye drops were subsequently administered 4 times/day until the complete disappearance of the pigmented lesions determined by slit-lamp examination...
July 27, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28751989/en-bloc-pancreaticoduodenectomy-for-locally-advanced-right-colon-cancers
#9
Cihan Ağalar, Aras Emre Canda, Tarkan Unek, Selman Sokmen
Locally advanced right colon cancer may invade adjacent tissue and organs. Direct invasion of the duodenum and pancreas necessitates an en bloc resection. Previously, this challenging procedure was associated with high morbidity and mortality; however, today, this procedure can be done more safely in experienced centers. The aim of this study is to report our experience on en bloc right colectomy with pancreaticoduodenectomy for locally advanced right colon cancers. Between 2000 and 2012, 5 patients underwent en bloc multivisceral resection...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28749194/results-of-preoperative-chemoradiotherapy-for-patients-with-advanced-cancer-of-the-nasal-cavity-and-paranasal-sinuses
#10
Erik Fernström, Jan Nyman, Eva Hammerlid, Erik Holmberg, Hedda Haugen-Cange, Karin Petruson, Edvard Abel, Thomas Björk-Eriksson
OBJECTIVES: Curative treatment of nasal cavity and paranasal sinus cancer is challenging due to the proximity to critical anatomical structures. The purpose of this study was to analyze the impact of trimodality therapy with preoperative chemotherapy and reduced-dose radiotherapy followed by organ-preserving surgery for treating patients with nasal cavity and paranasal sinus cancer. METHODS: This retrospective study included all 156 patients diagnosed with sinonasal cancer in western Sweden between 1986 and 2009...
July 27, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28747229/vaginal-metastasis-as-the-initial-presentation-of-leiomyosarcoma-a-case-report
#11
Cecilia Villalaín-González, Álvaro Tejerizo-García, Patricia Lopez-Garcia, Gregorio López-González, Ma Reyes Oliver-Perez, Jesús S Jiménez-López
BACKGROUND: Uterine leiomyosarcomas are very rare and highly aggressive tumors that have a high rate of recurrence and poor prognosis, even when early diagnosed. Due to their relative rarity, there is limited research on optimal management strategies. CASE PRESENTATION: A 60-year-old woman with a history of an asymptomatic uterine leiomyoma presented in October 2015 with postmenopausal bleeding and a friable vaginal cyst that bled when palpated. A partial cystectomy was performed, and malignant-like cystic and solid components were identified...
July 26, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28725521/naso-or-orbitocutaneous-fistulas-after-free-flap-reconstruction-of-orbital-exenteration-defects-retrospective-study-systematic-review-and-meta-analysis
#12
Patrick Tassone, Kurren S Gill, David Hsu, Gurston Nyquist, Howard Krein, Jurij R Bilyk, Anna P Murchison, James J Evans, Ryan N Heffelfinger, Joseph M Curry
Objective  Naso- or orbitocutaneous fistula (NOF) is a challenging complication of orbital exenteration, and it often requires surgical repair. We sought to identify the incidence and risk factors for NOF after orbital exenteration. Study Design  Retrospective chart review, systematic review, meta-analysis. Setting  Tertiary care center. Participants  Patients undergoing free flap reconstruction following orbital exenteration. Records were reviewed for clinicopathologic data, operative details, and outcomes...
August 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28721294/a-prospective-evaluation-of-surgical-outcomes-of-laparoscopic-transperitoneal-radical-cystectomy-anterior-pelvic-exenteration-our-surgical-technique-and-experience
#13
Anup Kumar, Niraj Kumar, Gaurav Kumar, Mikir Patel, Pankaj Gupta
No abstract text is available yet for this article.
June 30, 2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28695872/malignant-orbital-teratoma-in-a-neonate-a-clinicopathological-case-report
#14
M Vs Prakash, R Indira, M Radhakrishnan, G Leela
Teratoma of the orbit is rare; very few cases have been published in literature. A case of orbital teratoma in a neonate is presented where the proptosis was massive enough to obscure the eyeball. Clinically, the diagnosis of teratoma was considered. As there was no possibility of salvaging the eye, exenteration of the orbit was done. Orbital teratomas are generally benign. Histopathological examination revealed the features of malignant teratoma.
July 2017: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/28681210/sebaceous-carcinoma-a-review-of-the-scientific-literature
#15
REVIEW
Thomas Knackstedt, Faramarz H Samie
Sebaceous carcinoma is a rare and potentially aggressive cutaneous malignancy. Commonly reported in the periocular area and the head and neck region, sebaceous carcinoma can arise from any sebaceous gland in the skin. The clinical presentation may be nonspecific, and a biopsy is important to establish a diagnosis and to differentiate from mimickers including benign sebaceous neoplasms, other adnexal tumors, and basal cell carcinoma. A diagnosis of Muir Torre syndrome should be considered in patients presenting with a sebaceous neoplasm...
August 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/28673337/rare-presentation-of-intractable-tuberculous-panophthalmitis-with-intraocular-and-intraorbital-abscesses-a-case-report
#16
Sutasinee Boonsopon, Nattaporn Tesavibul, Mongkol Uiprasertkul, Supinda Leeamornsiri, Pitipol Choopong
BACKGROUND: We report a rare presentation of extrapulmonary tuberculosis. CASE PRESENTATION: A 29-year-old Burmese woman with human immunodeficiency virus infection and known pulmonary tuberculosis who had been treated for 5 months presented to our hospital with unilateral progressive painful visual loss of 1 month's duration. She was diagnosed with tuberculous panophthalmitis with subretinal and intraorbital abscesses, conjunctival abscess, and extraocular muscle tuberculoma...
July 4, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28660094/aqueous-deficient-dry-eye-syndrome-post-orbital-radiotherapy-a-10-year-retrospective-study
#17
Shubha Tiwari, Anusha Bhatt, Jayalaxmi Nagamodi, Mohammad Javed Ali, Hasnat Ali, Milind N Naik, Vijay Anand P Reddy, Geeta K Vemuganti
PURPOSE: Despite advances in orbital radiotherapy (XRT), a significant proportion of patients develop ophthalmic complication like dry eye syndrome (DES). The study evaluates the prevalence of aqueous deficient DES (ADDE) and lacrimal gland (LG) changes through histologic evaluation and ex-vivo expansion potential postorbital XRT. METHODS: With the approval of the institutional review board, medical records of patients who underwent orbital XRT as management protocol were reviewed for evidence of ADDE using DEWS (Dry Eye Workshop) 2007 criteria (n = 51)...
June 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28643706/orbital-retinoblastoma-an-update
#18
REVIEW
Santosh G Honavar, Fairooz P Manjandavida, Vijay Anand P Reddy
Orbital extension is a major cause of death in children with retinoblastoma in the developing countries. Delayed detection and inappropriate management contribute to poor outcome. Conventional treatment including primary orbital exenteration or chemotherapy or radiotherapy alone result in mortality as high as 70%. The recent understanding on the role of sequential multimodal therapy with a combination of high-dose chemotherapy, followed by appropriate surgery, radiotherapy, and additional adjuvant chemotherapy has helped dramatically improve life salvage...
June 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28638794/biological-mesh-reconstruction-of-the-pelvic-floor-following-abdominoperineal-excision-for-cancer-a-review
#19
REVIEW
Boris Schiltz, Nicolas Christian Buchs, Marta Penna, Cosimo Riccardo Scarpa, Emilie Liot, Philippe Morel, Frederic Ris
Extralevator abdominoperineal excision and pelvic exenteration are mutilating operations that leave wide perineal wounds. Such large wounds are prone to infection and perineal herniation, and their closure is a major concern to most surgeons. Different approaches to the perineal repair exist, varying from primary or mesh closure to myocutaneous flaps. Each technique has its own associated advantages and potential complications and the ideal approach is still debated. In the present study, we reviewed the current literature and our own local data regarding the use of biological mesh for perineal wound closure...
June 10, 2017: World Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28633250/permeable-nonabsorbable-mesh-for-total-diaphragmatic-replacement-in-extended-pneumonectomy
#20
Luigi Rolli, Giovanni Leuzzi, Paolo Girotti, Leonardo Duranti, Ugo Pastorino
After complex thoracic exenterations, total diaphragmatic resection and reconstruction is challenging. We describe our novel technique for total diaphragmatic replacement with permeable nonabsorbable mesh after extended pneumonectomy.
July 2017: Annals of Thoracic Surgery
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