keyword
MENU ▼
Read by QxMD icon Read
search

TMS-EEG

keyword
https://www.readbyqxmd.com/read/29766458/cerebellar-stimulation-evoked-prefrontal-electrical-synchrony-is-modulated-by-gaba
#1
Xiaoming Du, Laura M Rowland, Ann Summerfelt, Fow-Sen Choa, George F Wittenberg, Krista Wisner, Andrea Wijtenburg, Joshua Chiappelli, Peter Kochunov, L Elliot Hong
Cerebellar-prefrontal connectivity has been recognized as important for behaviors ranging from motor coordination to cognition. Many of these behaviors are known to involve excitatory or inhibitory modulations from the prefrontal cortex. We used cerebellar transcranial magnetic stimulation (TMS) with simultaneous electroencephalography (EEG) to probe cerebellar-evoked electrical activity in prefrontal cortical areas and used magnetic resonance spectroscopy (MRS) measures of prefrontal GABA and glutamate levels to determine if they are correlated with those potentials...
May 15, 2018: Cerebellum
https://www.readbyqxmd.com/read/29615366/ongoing-brain-rhythms-shape-i-wave-properties-in-a-computational-model
#2
Natalie Schaworonkow, Jochen Triesch
BACKGROUND: Responses to transcranial magnetic stimulation (TMS) are notoriously variable. Previous studies have observed a dependence of TMS-induced responses on ongoing brain activity, for instance sensorimotor rhythms. This suggests an opportunity for the development of more effective stimulation protocols through closed-loop TMS-EEG. However, it is not yet clear how features of ongoing activity affect the responses of cortical circuits to TMS. OBJECTIVE/HYPOTHESIS: Here we investigate the dependence of TMS-responses on power and phase of ongoing oscillatory activity in a computational model of TMS-induced I-waves...
March 20, 2018: Brain Stimulation
https://www.readbyqxmd.com/read/29432109/oscillatory-tms-eeg-responses-as-a-measure-of-the-cortical-excitability-threshold
#3
Jukka Saari, Elisa Kallioniemi, Mika Tarvainen, Petro Julkunen
Transcranial magnetic stimulation (TMS) is a non-invasive tool to perturb brain activity. In TMS studies, the stimulation intensity (SI) is commonly normalized to the resting motor threshold (rMT) that produces muscle responses in 50% of stimulations applied to the motor cortex (M1). Since rMT is influenced by spinal excitability and coil-to-cortex distance, responses recorded from the cortex, instead of a peripheral muscle, could provide a more accurate marker for cortical excitability. Combining TMS with electroencephalography (EEG) enables the measurement of brain-wide cortical reactivity to TMS...
February 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29407789/association-of-the-n100-tms-evoked-potential-with-attentional-processes-a-motor-cortex-tms-eeg-study
#4
Outi Kaarre, Marja Äikiä, Elisa Kallioniemi, Mervi Könönen, Virve Kekkonen, Noora Heikkinen, Petri Kivimäki, Tommi Tolmunen, Sara Määttä, Eila Laukkanen
The most thoroughly studied transcranial magnetic stimulation (TMS)-evoked electroencephalogram (EEG) potential (TEP), N100, is often defined as a measure of cortical inhibition. We explored the association of the N100 amplitude with attention in 51 young healthy adults. Navigated TMS with simultaneous EEG registering was applied over the left primary motor cortex at the intensity of 110% of the resting motor threshold. Attention was assessed with the Paced Auditory Serial Addition Test (PASAT). We found a negative Pearson correlation (p = ...
April 2018: Brain and Cognition
https://www.readbyqxmd.com/read/29352668/the-effect-of-single-and-repeated-prefrontal-intermittent-theta-burst-stimulation-on-cortical-reactivity-and-working-memory
#5
Sung Wook Chung, Nigel C Rogasch, Kate E Hoy, Paul B Fitzgerald
BACKGROUND: With an increasing interest in the use of theta burst stimulation (TBS) as a cognitive enhancer and a potential therapeutic tool for psychiatric disorders, there is a need to identify optimal parameters of TBS in the prefrontal cortex. OBJECTIVE/HYPOTHESIS: This study examined the effect of two blocks of prefrontal intermittent TBS (iTBS) on cortical reactivity and working memory performance, compared to one block of iTBS and sham stimulation. We hypothesized that greater cortical effects would be obtained with two blocks of iTBS...
January 8, 2018: Brain Stimulation
https://www.readbyqxmd.com/read/29342443/test-retest-reliability-of-transcranial-magnetic-stimulation-eeg-evoked-potentials
#6
Lewis J Kerwin, Corey J Keller, Wei Wu, Manjari Narayan, Amit Etkin
BACKGROUND: Transcranial magnetic stimulation (TMS)-evoked potentials (TEPs), recorded using electroencephalography (TMS-EEG), offer a powerful tool for measuring causal interactions in the human brain. However, the test-retest reliability of TEPs, critical to their use in clinical biomarker and interventional studies, remains poorly understood. OBJECTIVE/HYPOTHESIS: We quantified TEP reliability to: (i) determine the minimal TEP amplitude change which significantly exceeds that associated with simply re-testing, (ii) locate the most reliable scalp regions of interest (ROIs) and TEP peaks, and (iii) determine the minimal number of TEP pulses for achieving reliability...
December 29, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29331054/artist-a-fully-automated-artifact-rejection-algorithm-for-single-pulse-tms-eeg-data
#7
Wei Wu, Corey J Keller, Nigel C Rogasch, Parker Longwell, Emmanuel Shpigel, Camarin E Rolle, Amit Etkin
Concurrent single-pulse TMS-EEG (spTMS-EEG) is an emerging noninvasive tool for probing causal brain dynamics in humans. However, in addition to the common artifacts in standard EEG data, spTMS-EEG data suffer from enormous stimulation-induced artifacts, posing significant challenges to the extraction of neural information. Typically, neural signals are analyzed after a manual time-intensive and often subjective process of artifact rejection. Here we describe a fully automated algorithm for spTMS-EEG artifact rejection...
April 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29317185/cortical-inhibition-assessed-using-paired-pulse-tms-eeg-is-increased-in-older-adults
#8
George M Opie, Simranjit K Sidhu, Nigel C Rogasch, Michael C Ridding, John G Semmler
BACKGROUND: Alterations in inhibitory processes mediated by gamma-aminobutyric acid type B (GABAB ) receptors may contribute to age-related functional impairments. However, investigation of these circuits using conventional paired-pulse transcranial magnetic stimulation (TMS) at long interstimulus intervals (∼100-200ms) have produced conflicting results in older adults, possibly due to the indirect nature of the TMS motor evoked potential (MEP). OBJECTIVE: To utilise electroencephalography and TMS coregistration (TMS-EEG) to more directly assess age-related changes in GABAB -mediated long-interval intracortical inhibition (LICI)...
December 30, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29277405/transcranial-magnetic-stimulation-of-the-precuneus-enhances-memory-and-neural-activity-in-prodromal-alzheimer-s-disease
#9
Giacomo Koch, Sonia Bonnì, Maria Concetta Pellicciari, Elias P Casula, Matteo Mancini, Romina Esposito, Viviana Ponzo, Silvia Picazio, Francesco Di Lorenzo, Laura Serra, Caterina Motta, Michele Maiella, Camillo Marra, Mara Cercignani, Alessandro Martorana, Carlo Caltagirone, Marco Bozzali
Memory loss is one of the first symptoms of typical Alzheimer's disease (AD), for which there are no effective therapies available. The precuneus (PC) has been recently emphasized as a key area for the memory impairment observed in early AD, likely due to disconnection mechanisms within large-scale networks such as the default mode network (DMN). Using a multimodal approach we investigated in a two-week, randomized, sham-controlled, double-blinded trial the effects of high-frequency repetitive transcranial magnetic stimulation (rTMS) of the PC on cognition, as measured by the Alzheimer Disease Cooperative Study Preclinical Alzheimer Cognitive Composite in 14 patients with early AD (7 females)...
April 1, 2018: NeuroImage
https://www.readbyqxmd.com/read/29137988/tms-eeg-reveals-hemispheric-asymmetries-in-top-down-influences-of-posterior-intraparietal-cortex-on-behavior-and-visual-event-related-potentials
#10
Mika Koivisto, Simone Grassini, Mikko Hurme, Niina Salminen-Vaparanta, Henry Railo, Victor Vorobyev, Jussi Tallus, Teemu Paavilainen, Antti Revonsuo
Clinical data and behavioral studies using transcranial magnetic stimulation (TMS) suggest right-hemisphere dominance for top-down modulation of visual processing in humans. We used concurrent TMS-EEG to directly test for hemispheric differences in causal influences of the right and left intraparietal cortex on visual event-related potentials (ERPs). We stimulated the left and right posterior part of intraparietal sulcus (IPS1) while the participants were viewing and rating the visibility of bilaterally presented Gabor patches...
December 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29124791/impact-of-different-intensities-of-intermittent-theta-burst-stimulation-on-the-cortical-properties-during-tms-eeg-and-working-memory-performance
#11
Sung Wook Chung, Nigel C Rogasch, Kate E Hoy, Caley M Sullivan, Robin F H Cash, Paul B Fitzgerald
Intermittent theta burst stimulation (iTBS) is a noninvasive brain stimulation technique capable of increasing cortical excitability beyond the stimulation period. Due to the rapid induction of modulatory effects, prefrontal application of iTBS is gaining popularity as a therapeutic tool for psychiatric disorders such as depression. In an attempt to increase efficacy, higher than conventional intensities are currently being applied. The assumption that this increases neuromodulatory may be mechanistically false for iTBS...
February 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29104528/the-effect-of-lamotrigine-and-levetiracetam-on-tms-evoked-eeg-responses-depends-on-stimulation-intensity
#12
Isabella Premoli, Alyssa Costantini, Davide Rivolta, Andrea Biondi, Mark P Richardson
The combination of transcranial magnetic stimulation and electroencephalography (TMS-EEG) has uncovered underlying mechanisms of two anti-epileptic medications: levetiracetam and lamotrigine. Despite their different mechanism of action, both drugs modulated TMS-evoked EEG potentials (TEPs) in a similar way. Since both medications increase resting motor threshold (RMT), the current aim was to examine the similarities and differences in post-drug TEPs, depending on whether stimulation intensity was adjusted to take account of post-drug RMT increase...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29103999/improving-the-quality-of-combined-eeg-tms-neural-recordings-introducing-the-coil-spacer
#13
K L Ruddy, D G Woolley, D Mantini, J H Balsters, N Enz, N Wenderoth
BACKGROUND: In the last decade, interest in combined transcranial magnetic stimulation (TMS) and electroencephalography (EEG) approaches has grown substantially. Aside from the obvious artifacts induced by the magnetic pulses themselves, separate and more sinister signal disturbances arise as a result of contact between the TMS coil and EEG electrodes. NEW METHOD: Here we profile the characteristics of these artifacts and introduce a simple device - the coil spacer - to provide a platform allowing physical separation between the coil and electrodes during stimulation...
January 15, 2018: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28728060/clinical-neurophysiology-of-prolonged-disorders-of-consciousness-from-diagnostic-stimulation-to-therapeutic-neuromodulation
#14
REVIEW
Aldo Ragazzoni, Massimo Cincotta, Fabio Giovannelli, Damian Cruse, G Bryan Young, Carlo Miniussi, Simone Rossi
The identification of signs of awareness in patients with prolonged disorders of consciousness (DoC) after severe brain injury is a challenging task for clinicians. Differentiating on behavioural examination the vegetative state (VS) from the minimally conscious state (MCS) can lead to a high misdiagnosis rate. Advanced neuroimaging and neurophysiological techniques can supplement clinical evaluation by providing physiological evidence of brain activity. However, an open issue remains whether these empirical results are directly or indirectly associated with covert consciousness and limitations emerge for their diagnostic application at the single-patient level...
September 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28709122/tms-evoked-long-lasting-artefacts-a-new-adaptive-algorithm-for-eeg-signal-correction
#15
Elias P Casula, Alessandra Bertoldo, Vincenza Tarantino, Michele Maiella, Giacomo Koch, John C Rothwell, Gianna M Toffolo, Patrizia S Bisiacchi
OBJECTIVE: During EEG the discharge of TMS generates a long-lasting decay artefact (DA) that makes the analysis of TMS-evoked potentials (TEPs) difficult. Our aim was twofold: (1) to describe how the DA affects the recorded EEG and (2) to develop a new adaptive detrend algorithm (ADA) able to correct the DA. METHODS: We performed two experiments testing 50 healthy volunteers. In experiment 1, we tested the efficacy of ADA by comparing it with two commonly-used independent component analysis (ICA) algorithms...
September 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28702347/tdcs-modulates-cortical-excitability-in-patients-with-disorders-of-consciousness
#16
Yang Bai, Xiaoyu Xia, Jiannan Kang, Yi Yang, Jianghong He, Xiaoli Li
Transcranial direct current stimulation (tDCS) has been reported to be a promising technique for consciousness improvement for patients with disorders of consciousness (DOC). However, there has been no direct electrophysiological evidence to demonstrate the efficacy of tDCS on patients with DOC. Therefore, we aim to measure the cortical excitability changes induced by tDCS in patients with DOC, to find electrophysiological evidence supporting the therapeutic efficacy of tDCS on patients with DOC. In this study, we enrolled sixteen patients with DOC, including nine vegetative state (VS) and seven minimally conscious state (MCS) (six females and ten males)...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28624571/age-related-changes-of-cortical-excitability-and-connectivity-in-healthy-humans-non-invasive-evaluation-of-sensorimotor-network-by-means-of-tms-eeg
#17
Florinda Ferreri, Andrea Guerra, Luca Vollero, David Ponzo, Sara Maatta, Esa Mervaala, Giulio Iannello, Vincenzo Di Lazzaro
The sensorimotor cortical system undergoes structural and functional changes across its lifespan. Some of these changes are physiological and parallel the normal aging process, while others might represent pathophysiological mechanisms underlying neurodegenerative disorders. In the last years, the study of possible age-related modifications in brain sensorimotor functional characteristics has been the focus of several research projects. Here we have used the transcranial magnetic stimulation (TMS)-electroencephalography (EEG) navigated co-registration to investigate the influence of physiological aging on the excitability and connectivity of the human sensorimotor cortical system...
June 15, 2017: Neuroscience
https://www.readbyqxmd.com/read/28615277/alterations-in-the-brain-s-connectome-during-recovery-from-severe-traumatic-brain-injury-protocol-for-a-longitudinal-prospective-study
#18
Virginia Conde, Sara Hesby Andreasen, Tue Hvass Petersen, Karen Busted Larsen, Karine Madsen, Kasper Winther Andersen, Irina Akopian, Kristoffer Hougaard Madsen, Christian Pilebæk Hansen, Ingrid Poulsen, Lars Peter Kammersgaard, Hartwig Roman Siebner
INTRODUCTION: Traumatic brain injury (TBI) is considered one of the most pervasive causes of disability in people under the age of 45. TBI often results in disorders of consciousness, and clinical assessment of the state of consciousness in these patients is challenging due to the lack of behavioural responsiveness. Functional neuroimaging offers a means to assess these patients without the need for behavioural signs, indicating that brain connectivity plays a major role in consciousness emergence and maintenance...
June 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/28604171/abnormal-eeg-responses-to-tms-during-the-cortical-silent-period-are-associated-with-hand-function-in-chronic-stroke
#19
Whitney A Gray, Jacqueline A Palmer, Steven L Wolf, Michael R Borich
BACKGROUND: Abnormal brain excitability influences recovery after stroke at which time a prolonged transcranial magnetic stimulation (TMS)-induced electromyographic silent period is thought to reflect abnormal inhibitory interneuron excitability. Cortical excitability can be probed directly during the silent period using concurrent electroencephalography (EEG) of TMS-evoked responses. OBJECTIVE: The primary study objectives were to characterize TMS-evoked cortical potentials (TEPs) using EEG and to investigate associations with persistent hand and arm motor dysfunction in individuals with chronic stroke...
July 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28553835/pharmacological-manipulation-of-cortical-inhibition-in-the-dorsolateral-prefrontal-cortex
#20
Bahar Salavati, Tarek K Rajji, Reza Zomorrodi, Daniel M Blumberger, Robert Chen, Bruce G Pollock, Zafiris J Daskalakis
Cortical inhibition (CI) occurs largely through GABA receptor mediated inhibitory neurotransmission, which can be modulated by cholinergic, dopaminergic, and glutamatergic inputs. Transcranial magnetic stimulation (TMS) can be used to index CI through a paradigm known as long interval cortical inhibition (LICI). When TMS is combined with electroencephalography (EEG), LICI can index GABA receptor mediated inhibitory neurotransmission in the dorsolateral prefrontal cortex (DLPFC). We conducted a hypothesis-driven pharmacological study to assess the role of cholinergic, dopaminergic, GABAergic, and glutamatergic neurotransmission on LICI from the DLPFC using TMS-EEG...
May 29, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
keyword
keyword
61121
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"