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Giacomo Strapazzon, Oliver Reisten, Fabien Argenone, Ken Zafren, Greg Zen-Ruffinen, Gordon L Larsen, Inigo Soteras
Canyoning is a recreational activity that has increased in popularity in the last decade in Europe and North America, resulting in up to 40% of the total search and rescue costs in some geographic locations. The International Commission for Mountain Emergency Medicine convened an expert panel to develop recommendations for on-site management and transport of patients in canyoning incidents. The goal of the current review is to provide guidance to healthcare providers and canyoning rescue professionals about best practices for rescue and medical treatment through the evaluation of the existing best evidence, focusing on the unique combination of remoteness, water exposure, limited on-site patient management options, and technically challenging terrain...
February 13, 2018: Wilderness & Environmental Medicine
Patricia Castellano, Natalia Peña, Mariana Pérez Ibarreche, Fernando Carduza, Trinidad Soteras, Graciela Vignolo
Dipping solutions containing bacteriocins produced by Lactobacillus curvatus CRL705 and Lactobacillus sakei CRL1862 (Bact705/1862), nisin and organic acids (lactic acid, LA; acetic acid, AA) were tested alone or in combination against Listeria monocytogenes inoculated by immersion on vacuum-packaged frankfurters stored at 10 °C during 36 days. LA/AA solution (2.5% v/v each) reduced pathogen population by 1.50 log10 CFU/ml during storage. Semi-purified Bact705/1862 prevented L. monocytogenes growth, while nisin was not able to avoid its regrowth after 20 days...
February 2018: Journal of Food Science and Technology
Marco Di Luca, Luciano Toma, Francesco Severini, Daniela Boccolini, Salvatore D'Avola, Diego Todaro, Alessandra Stancanelli, Francesco Antoci, Francesco La Russa, Sandro Casano, Salvatore D Sotera, Eugenio Carraffa, Veerle Versteirt, Francis Schaffner, Roberto Romi, Alessandra Torina
BACKGROUND: Aedes albopictus, a known worldwide vector of several mosquito-borne disease pathogens including dengue, chikungunya and Zika viruses, was introduced into Europe in the late 1970s through global trade. First recorded in northern Italy in 1990, this mosquito species has rapidly spread throughout the country, where it was responsible for an outbreak of chikungunya in 2007 that affected more than 200 people. As part of the VectorNet project, which is aimed at improving preparedness and responsiveness for animal and human vector-borne diseases in Europe, a mosquito targeted study was carried out on the three southernmost Italian islands...
November 2, 2017: Parasites & Vectors
Diego Velasco-Rodríguez, Miguel Piris-Villaespesa, Carmen Soteras, Ana Vallés, José Antonio García-Marco, José Antonio García-Vela
Chronic lymphocytic leukemia (CLL) is an incurable lymphoproliferative disorder with a heterogeneous genetic and clinical course. Two kinase inhibitors, ibrutinib and idelalisib, have demonstrated achievement of complete and durable remissions in relapse/refractory genetically unselected CLL patients. We present a case of relapsed CLL with extensive disease and hourglass deformity of urinary bladder as a result of the compression of two extraperitoneal paravesical soft tissue bulky masses, with excellent response to sequential kinase inhibitor therapy...
2017: Case Reports in Hematology
Mariska Weenk, Harry van Goor, Bas Frietman, Lucien Jlpg Engelen, Cornelis Jhm van Laarhoven, Jan Smit, Sebastian Jh Bredie, Tom H van de Belt
BACKGROUND: Measurement of vital signs in hospitalized patients is necessary to assess the clinical situation of the patient. Early warning scores (EWS), such as the modified early warning score (MEWS), are generally calculated 3 times a day, but these may not capture early deterioration. A delay in diagnosing deterioration is associated with increased mortality. Continuous monitoring with wearable devices might detect clinical deterioration at an earlier stage, which allows clinicians to take corrective actions...
July 5, 2017: JMIR MHealth and UHealth
David Virós Porcuna, Francisco Avilés Jurado, Carlos Pollán Guisasola, Rosa Delia Ramírez Ruiz, Jacinto García Lorenzo, Marc Tobed Secall, Isabel Vilaseca González, José Miguel Costa González, Josep Soteras Olle, Francesc Casamitjana Claramunt, Anna Sumarroca Trouboul, Rafael Hijano Esqué, Guillem Viscasillas Pallàs, Manel Mañós Pujol, Miquel Quer Agustí
INTRODUCTION AND GOALS: There has been a very significant increase in the use of minimally invasive surgery has in the last decade. In order to provide a common language after transoral surgery of the oropharynx, a system for classifying resections has been created in this area, regardless of the instrumentation used. METHODS: From the Oncology Working Group of the Catalan Society of Otorhinolaryngology, a proposal for classification based on a topographical division of the different areas of the oropharynx is presented, as also based on the invasion of the related structures according to the anatomical routes of extension of these tumours...
May 11, 2017: Acta Otorrinolaringológica Española
Manuel Mendizabal, Leila Haddad, Patricia E Gallardo, Alejandro Ferrada, Alejandro A Soza, Raul Adrover, Edmundo Aravena, Juan P Roblero, Jhon Prieto, Claudia Vujacich, Gustavo Romero, Alberto Muñoz, Margarita Anders, Nelia Hernández, Daniel Coccozella, Fernando Gruz, Maria V Reggiardo, Andres E Ruf, Adriana Varón, Mariano Cartier, Roberto Pérez Ravier, Ezequiel Ridruejo, Mirta Peralta, Daniel Poncino, Julio Vorobioff, Gabriel Aballay Soteras, Marcelo O Silva
Information about the use of ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin (OBV/PTV/r/DSV ± RBV) in real-clinical practice in Latin America is scarce. We aimed to confirm safety and effectiveness of OBV/PTV/r/DSV ± RBV therapy in real-world setting. We analyzed a cohort of patients with genotype 1 infection treated with OBV/PTV/r/DSV ± RBV. Data on demographics, clinical features, safety, and virological response were retrospectively collected from 21 centers in Latin America. A total of 96 patients received OBV/PTV/r/DSV, associated with RBV in 68% of the cases...
September 2017: Journal of Medical Virology
Silvana Pinheiro, Ignacio Soteras, Josep Lluis Gelpí, François Dehez, Christophe Chipot, F Javier Luque, Carles Curutchet
Cation-π interactions of aromatic rings and positively charged groups are among the most important interactions in structural biology. The role and energetic characteristics of these interactions are well established. However, the occurrence of cation-π-cation interactions is an unexpected motif, which raises intriguing questions about its functional role in proteins. We present a statistical analysis of the occurrence, composition and geometrical preferences of cation-π-cation interactions identified in a set of non-redundant protein structures taken from the Protein Data Bank...
April 12, 2017: Physical Chemistry Chemical Physics: PCCP
E Cardo, G Ros-Cervera, J Eiris-Punal, C Escofet-Soteras, A Fernandez-Jaen, F Mulas, R Sanchez-Carpintero, A Sans, Grupo de Trabajo de Tdah de la Sociedad Espanola de Neurologia Pediatrica Grupo de Trabajo de Tdah de la Sociedad Espanola de Neurologia Pediatrica
AIM: To know the current state of the approach of attention deficit hyperactivity disorder (ADHD) in neuropediatricians. SUBJECTS AND METHODS: A telematic survey was carried out to collect preliminary information on the interest, difficulties in the management and treatment of ADHD to the 437 fellowship of the Neuropediactric Spanish Society (SENEP). RESULTS: Only 32.49% of the sent questionnaires were answered, with important geographic variability...
February 24, 2017: Revista de Neurologia
Carlos Brotons, Irene Moral, Diana Fernández, Lluis Cuixart, Alex Muñoz, Anna Soteras, Mireia Puig, Xavier Joaniquet, Albert Casasa
No abstract text is available yet for this article.
March 3, 2017: Medicina Clínica
Carlos Brotons, Irene Moral, Diana Fernández, Lluis Cuixart, Alex Muñox, Anna Soteras, Mireia Puig, Xavier Joaniquet, Albert Casasa
BACKGROUND AND OBJECTIVE: Estimating cardiovascular risk with SCORE is not recommended in persons over 65 years. SCORE investigators have recently published specific tables for older people (SCORE Older Persons [SCORE OP]). The aim of this study is to assess the impact of using SCORE OP tables on a Spanish population aged over 64 years, and compare it with the use of SCORE in patients aged 65-69 years. PATIENTS AND METHOD: Cross-sectional study carried out in 2 urban primary health care centres...
November 4, 2016: Medicina Clínica
Carlos Brotons, Irene Moral, Diana Fernández, Lluís Cuixart, Anna Soteras, Mireia Puig
No abstract text is available yet for this article.
October 2016: Revista Española de Cardiología
Ignacio Soteras Gutiérrez, Fang-Yu Lin, Kenno Vanommeslaeghe, Justin A Lemkul, Kira A Armacost, Charles L Brooks, Alexander D MacKerell
A halogen bond is a highly directional, non-covalent interaction between a halogen atom and another electronegative atom. It arises due to the formation of a small region of positive electrostatic potential opposite the covalent bond to the halogen, called the 'sigma hole.' Empirical force fields in which the electrostatic interactions are represented by atom-centered point charges cannot capture this effect because halogen atoms usually carry a negative charge and therefore interact unfavorably with other electronegative atoms...
October 15, 2016: Bioorganic & Medicinal Chemistry
Katharina Grasegger, Giacomo Strapazzon, Emily Procter, Hermann Brugger, Inigo Soteras
We report a case of survival of a completely buried avalanche victim after being located with the radar-based RECCO Rescue System. In the winter of 2015, 2 off-piste skiers were completely buried in an avalanche near the secured ski area in Baqueira Beret, Spain. The first victim was located with the RECCO Rescue System in less than 35 minutes and was alive and conscious at extrication. This system emits radio waves and requires a specific reflector. It is a portable device that is used by more than 600 rescue organizations worldwide, especially in secured ski areas...
June 2016: Wilderness & Environmental Medicine
Javier Monleón Sancho, Verónica Serrano de la Cruz Delgado, Maria José Nuñez Valero, Marta Gurrea Soteras, Vicente Payá Amate, Antonio Abad Carrascosa
Ulipristal Acetate (UPA) modifies the endometrium, as well as fibroids, and therefore it might make hysteroscopic surgery more difficult. To confirm that pre-treatment with UPA is as safe and effective an option as pre-treatment with GnRH analogues, considered the gold standard. We present the first series of 26 hysteroscopic myomectomies after 3 months treatment with UPA and we compare the results with a series of 24 cases pretreated with GnRH analogues. This was a retrospective cohort study between July 2013 and May 2015...
March 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
C Oroviogoicoechea, A Carvajal, M A Soteras, E Beortegui, C de la Hera, M A Aznárez
BACKGROUND: The Oral Assessment Guide (OAG) is a widely used tool designed for evaluating problems of oral mucous in cancer patients, but it has not been validated in Spanish. The aim of this work is to translate and validate into Spanish the scale of the OAG designed by Eilers. METHOD: The translation process was carried out using the method of back-translation by bilingual translators. The study was carried out with cancer patients, both outpatient and inpatients, of the Hematology/Oncology Department and with oncology nurses...
May 2015: Anales del Sistema Sanitario de Navarra
Inigo Soteras, Enric Subirats, Giacomo Strapazzon
AIM: To describe the characteristics of canyoning rescue operations (CRO), type and severity of injuries or illnesses, and on-site medical procedures. PATIENTS AND METHODS: A retrospective analysis of all CRO data from an emergency medical rescue team in Aragon, Spain, between 1 August 1999 and 31 July 2009. RESULTS: A total of 520 patients were identified, with a male to female ratio of 1.4. The median age was 32 years (range 10-73 years)...
April 2015: Injury
Y Yang-Hartwich, M G Soteras, Z P Lin, J Holmberg, N Sumi, V Craveiro, M Liang, E Romanoff, J Bingham, F Garofalo, A Alvero, G Mor
High-grade serous ovarian carcinoma (HGSOC), the most lethal gynecological cancer, often leads to chemoresistant diseases. The p53 protein is a key transcriptional factor regulating cellular homeostasis. A majority of HGSOCs have inactive p53 because of genetic mutations. However, genetic mutation is not the only cause of p53 inactivation. The aggregation of p53 protein has been discovered in different types of cancers and may be responsible for impairing the normal transcriptional activation and pro-apoptotic functions of p53...
July 2015: Oncogene
Alejandra Becerra, Norberto Bartoloni, Noelia Cofré, Florencia Soteras, Marta Cabello
Arbuscular mycorrhizal fungi (AMF) colonize land plants in every ecosystem, even extreme conditions such as saline soils. In the present work we report for the first time the mycorrhizal status and the vertical fungal distribution of AMF spores present in the rhizospheric soil samples of four species of Chenopodiaceae (Allenrolfea patagonica, Atriplex argentina, Heterostachys ritteriana and Suaeda divaricata) at five different depths in two saline of central Argentina. Roots showed medium, low or no colonization (0-50%)...
2014: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
Yang Yang-Hartwich, Marta Gurrea-Soteras, Natalia Sumi, Won Duk Joo, Jennie C Holmberg, Vinicius Craveiro, Ayesha B Alvero, Gil Mor
The mortality rate of ovarian cancer remains high due to late diagnosis and recurrence. A fundamental step toward improving detection and treatment of this lethal disease is to understand its origin. A growing number of studies have revealed that ovarian cancer can develop from multiple extra-ovarian origins, including fallopian tube, gastrointestinal tract, cervix and endometriosis. However, the mechanism leading to their ovarian localization is not understood. We utilized in vitro, ex vivo, and in vivo models to recapitulate the process of extra-ovarian malignant cells migrating to the ovaries and forming tumors...
2014: Scientific Reports
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