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https://www.readbyqxmd.com/read/29906421/effectiveness-of-pulmonary-rehabilitation-in-patients-with-chronic-obstructive-pulmonary-disease-with-different-degrees-of-static-lung-hyperinflation
#1
Michiel J E G W Vanfleteren, Maud Koopman, Martijn A Spruit, Herman-Jan Pennings, Frank Smeenk, Willem Pieters, Jan J A M van den Bergh, Arent-Jan Michels, Emiel F M Wouters, Miriam T J Groenen, Frits M E Franssen, Lowie E G W Vanfleteren
OBJECTIVE: To evaluate the effect of pulmonary rehabilitation (PR) on exercise performance and quality of life in patients with chronic obstructive pulmonary disease (COPD) with different degrees of static lung hyperinflation (LH). DESIGN: Retrospective cohort study. SETTING: Pulmonary Rehabilitation Network. PARTICIPANTS: A cohort of 1981 patients with COPD (55% males; age: 66.8 ± 9.3y; FEV1%: 50.7 ± 19.5; RV%: 163...
June 12, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29904584/new-targets-for-resolution-of-airway-remodeling-in-obstructive-lung-diseases
#2
REVIEW
Ajay P Nayak, Deepak A Deshpande, Raymond B Penn
Airway remodeling (AR) is a progressive pathological feature of the obstructive lung diseases, including asthma and chronic obstructive pulmonary disease (COPD). The pathology manifests itself in the form of significant, progressive, and (to date) seemingly irreversible changes to distinct respiratory structural compartments. Consequently, AR correlates with disease severity and the gradual decline in pulmonary function associated with asthma and COPD. Although current asthma/COPD drugs manage airway contraction and inflammation, none of these effectively prevent or reverse features of AR...
2018: F1000Research
https://www.readbyqxmd.com/read/29903861/combined-value-of-exhaled-nitric-oxide-and-blood-eosinophils-in-chronic-airway-disease-the-copenhagen-general-population-study
#3
Yunus Çolak, Shoaib Afzal, Børge G Nordestgaard, Jacob L Marott, Peter Lange
We investigated whether the combination of increased fraction of exhaled nitric oxide (FeNO) level and blood eosinophil count had an additive value in chronic airway disease in the general population.We included 4677 individuals aged 20-100 years from the Copenhagen General Population Study. Based on pre- and post-bronchodilator spirometry, self-reported asthma, and smoking history, participants were subdivided into:healthy never-smokers (n=1649), healthy ever-smokers (n=1581), asthma (n=449), chronic obstructive pulmonary disease (COPD) (n=404), asthma-COPD overlap (ACO) (n=138), and non-specific airflow limitation (n=456)...
June 14, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29903607/improvement-of-physical-activity-in-chronic-obstructive-pulmonary-disease-by-pulmonary-rehabilitation-and-pharmacological-treatment
#4
REVIEW
Takanobu Shioya, Susumu Sato, Masahiro Iwakura, Hitomi Takahashi, Yoshino Terui, Sachiko Uemura, Masahiro Satake
Physical activity (PA) is defined as bodily movement produced by skeletal muscles with energy expenditure beyond resting levels. PA is closely related to reduced morbidity and mortality in chronic obstructive pulmonary disease (COPD). Self-report questionnaires are often subject to recall bias, correlating poorly with objectively qualified PA, and do not provide an accurate estimate of free-living energy expenditure. PA may be objectively evaluated by newly developed tri-axial accelerometers by quantifying steps or body movements over a period of time...
June 11, 2018: Respiratory Investigation
https://www.readbyqxmd.com/read/29899047/self-management-of-patients-with-mild-copd-in-primary-care-randomised-controlled-trial
#5
Kate Jolly, Manbinder S Sidhu, Catherine A Hewitt, Peter A Coventry, Amanda Daley, Rachel Jordan, Carl Heneghan, Sally Singh, Natalie Ives, Peymane Adab, Susan Jowett, Jinu Varghese, David Nunan, Khaled Ahmed, Lee Dowson, David Fitzmaurice
OBJECTIVE: To evaluate the effectiveness of telephone health coaching delivered by a nurse to support self management in a primary care population with mild symptoms of chronic obstructive pulmonary disease (COPD). DESIGN: Multicentre randomised controlled trial. SETTING: 71 general practices in four areas of England. PARTICIPANTS: 577 patients with Medical Research Council dyspnoea scale scores of 1 or 2, recruited from primary care COPD registers with spirometry confirmed diagnosis...
June 13, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29898904/should-i-stay-or-should-i-go-copd-and-air-travel
#6
REVIEW
Begum Ergan, Metin Akgun, Angela Maria Grazia Pacilli, Stefano Nava
Chronic obstructive pulmonary disease (COPD) is a challenging respiratory problem throughout the world. Although survival is prolonged with new therapies and better management, the magnitude of the burden resulting from moderate-to-severe disease is increasing. One of the major aims of the disease management is to try to break the vicious cycle of patients being homebound and to promote an active lifestyle. A fundamental component of active daily life is, of course, travelling. Today, the world is getting smaller with the option of travelling by air...
June 30, 2018: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/29894209/childhood-respiratory-risk-factor-profiles-their-interactions-and-mediators-and-middle-age-lung-function-a-prospective-cohort-study-from-the-1st-to-6th-decade
#7
Dinh S Bui, Haydn E Walters, John A Burgess, Jennifer L Perret, Minh Q Bui, Gayan Bowatte, Adrian J Lowe, Melissa A Russell, Bruce R Thompson, Garun S Hamilton, Alan L James, Graham G Giles, Paul S Thomas, Debbie Jarvis, Cecilie Svanes, Judith Garcia-Aymerich, Bircan Erbas, Peter A Frith, Katrina J Allen, Michael J Abramson, Caroline J Lodge, Shyamali C Dharmage
RATIONALE: Childhood risk factors for long-term lung health often co-exist and their specific patterns may affect subsequent lung function differently. OBJECTIVES: To identify childhood risk factor profiles, their influence on lung function and chronic obstructive pulmonary disease (COPD) in middle-age and potential pathways. METHODS: Profiles of 11 childhood respiratory risk factors, documented at age 7, were identified in 8352 participants from the Tasmanian Longitudinal Health Study using latent class analysis...
June 12, 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29889828/sleepiness-fatigue-anxiety-and-depression-in-chronic-obstructive-pulmonary-disease-and-obstructive-sleep-apnea-overlap-syndrome-before-and-after-continuous-positive-airways-pressure-therapy
#8
Nicholas-Tiberio Economou, Ioannis Ilias, Lemonia Velentza, Yiannis Papachatzakis, Paul Zarogoulidis, Anastasios Kallianos, Georgia Trakada
Patients with Chronic Obstructive Pulmonary Disease (COPD) and / or Obstructive Sleep Apnea (OSA) often complain about sleepiness, fatigue, anxiety and depression. However, common screening questionnaires, like Epworth Sleepiness Scale (ESS), Fatigue Severity Scale (FSS) and Hospital Anxiety and Depression Scale (HADS) have not been previous evaluated in patients with overlap-coexisting COPD and OSA-syndrome versus patients with OSA alone. Our study compared ESS, FSS and HADS between patients with overlap syndrome and patients with OSA, before and after treatment with Continuous Positive Airways Pressure (CPAP)...
2018: PloS One
https://www.readbyqxmd.com/read/29888577/-electroacupuncture-intervention-improved-pulmonary-function-via-promoting-immunoregulation-in-chronic-obstructive-pulmonary-disease-rats
#9
Juan Tong, Fu-Chu Chen, Gui-Yuan Li, Xiang-Ao Kong, Ying He, Hong Yao
OBJECTIVE: To observe the immunoregulatory effect of electroacupuncture (EA) intervention for muscular dystrophy chronic obstructive pulmonary disease (COPD) rats, so as to investigate its underlying mechanism in improving respiratory function. METHODS: Forty male SD rats were randomly divided into 5 groups: normal, model, EA, exercise, and EA+ exercise ( n =8 in each). The muscular dystrophy COPD model was established by placing the rats in a closed box to be exposed to cigarette smoke (3-10 cigarettes/time) for 60 min, twice daily, 6 days a week for 90 days...
April 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29886708/the-impact-of-air-pollution-including-asian-sand-dust-on-respiratory-symptoms-and-health-related-quality-of-life-in-outpatients-with-chronic-respiratory-disease-in-korea-a-panel-study
#10
Motoyuki Nakao, Yoko Ishihara, Cheol-Hong Kim, In-Gyu Hyun
OBJECTIVES: Air pollution is a growing concern in Korea because of transboundary air pollution from mainland China. A panel study was conducted to clarify the effects of air pollution on respiratory symptoms and health-related quality of life (HR-QoL) in outpatients with and without chronic obstructive pulmonary disease (COPD) in Korea. METHODS: Patients filled out a questionnaire including self-reported HR-QoL in February and were followed up in May and July. The study was conducted from 2013 to 2015, with different participants each year...
May 2018: Journal of Preventive Medicine and Public Health, Yebang Ŭihakhoe Chi
https://www.readbyqxmd.com/read/29886069/repurposing-of-gamma-interferon-via-inhalation-delivery
#11
Gerald C Smaldone
Pulmonary diseases frequently involve imbalances in immunity. The inability to control bacteria in tuberculosis is a failed response to a pathogen. Idiopathic pulmonary fibrosis (IPF), a progressive fibrotic lung disease, can lead to respiratory failure and death within 3 years of diagnosis. Chronic obstructive pulmonary disease (COPD) progresses until death and in recent years has been labeled an autoimmune disease. Proposed mechanistic pathways of pathophysiology involve uncontrolled healing governed by pro-fibrotic cytokines that are unresponsive to the standard anti-inflammatory agents (e...
June 7, 2018: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29883359/influence-of-risk-factors-on-development-of-chronic-obstructive-pulmonary-disease-and-legislative-foundations-for-copd-medical-care-in-ukraine
#12
Vasyl M Mykhalchuk, Averian G Vasyliev
OBJECTIVE: Introduction: Out of all respiratory diseases COPD is the leading cause of death and is characterized with diffuse non-reversible airway obstruction. Many various components play role in development and progression of this disease, while COPD risk factors play the most prominent role. Further progress in healthcare system development around COPD in Ukraine requires analysis of legislation, regulating pulmonological medical service in Ukraine. The aim: To analyze the influence of major risk factors on the development of chronic obstructive pulmonary disease and to determine key legislative aspects of the organization of medical care for COPD patients in Ukraine...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29881436/role-of-vitamin-d-replacement-on-health-related-quality-of-life-in-hospitalized-patients-with-acute-exacerbation-of-chronic-obstructive-pulmonary-disease
#13
Mouhamad Hasan Pourrashid, Farzaneh Dastan, Jamshid Salamzadeh, Alireza Eslaminejad, Maryam Edalatifard
Burden of Chronic Obstructive Pulmonary Disease (COPD) is substantial and increasing in the world. There are controversial reports regarding vitamin D supplementation in COPD. We investigated relationship between vitamin D3 (Cholecalciferol) supplementation with Health Related Quality of Life (HRQOL) and symptom recovery in AECOPD patients with concurrent Vitamin D Deficiency (VDD). A placebo-controlled randomized clinical trial was designed. AECOPD patients with VDD were randomly allocated to receive either vitamin D 300,000 IU (n = 35) or placebo (n = 35) by intramuscular injection...
2018: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/29879019/diagnostic-value-of-fractional-exhaled-nitric-oxide-for-asthma-chronic-obstructive-pulmonary-disease-overlap-syndrome
#14
Yuanyuan Guo, Chunlin Hong, Yanhong Liu, Huinuan Chen, Xiaohua Huang, Minli Hong
To examine the difference in the fractional exhaled nitric oxide (FeNO) between chronic obstructive pulmonary disease (COPD) patients with asthma-COPD overlap syndrome (ACOS) and patients with Non-ACOS COPD (Non-ACOS) and to investigate the correlation between FeNO levels and the differential cell counts of eosinophils in induced sputum, in order to explore the diagnostic value of FeNO in ACOS.A prospective, case-control study was performed on 53 cases of ACOS group and 53 cases of Non-ACOS group in the Respiratory Medicine Outpatient of Zhangzhou Municipal TCM Hospital, Affiliated to Fujian University of Traditional Chinese Medicine...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29876857/ambient-air-pollution-of-particles-and-gas-pollutants-and-the-predicted-health-risks-from-long-term-exposure-to-pm-2-5-in-zhejiang-province-china
#15
Yuanchen Chen, Lu Zang, Wei Du, Da Xu, Guofeng Shen, Quan Zhang, Qiaoli Zou, Jinyuan Chen, Meirong Zhao, Defei Yao
In recent years, ambient air has been severely contaminated by particulate matters (PMs) and some gas pollutants (nitrogen dioxide (NO2 ) and sulfur dioxide (SO2 )) in China, and many studies have demonstrated that exposure to these pollutants can induce great adverse impacts on human health. The concentrations of the pollutants were much higher in winter than those in summer, and the average concentrations in this studied area were lower than those in northern China. In the comparison between high-resolution emission inventory and spatial distribution of PM2...
June 6, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29874659/practice-patterns-for-chronic-respiratory-diseases-in-the-asia-pacific-region-a-cross-sectional-observational-study
#16
De Yun Wang, Sang-Heon Cho, Horng-Chyuan Lin, Aloke Gopal Ghoshal, Abdul Razak Bin Abdul Muttalif, Sanguansak Thanaviratananich, Kaan Tunceli, Eduardo Urdaneta, Dongmu Zhang, Rab Faruqi
BACKGROUND: Allergic rhinitis (AR), asthma, chronic obstructive pulmonary disease (COPD), and rhinosinusitis are common and little studied in the Asia-Pacific region. OBJECTIVES: We sought to investigate real-world practice patterns for these respiratory diseases in India, Korea, Malaysia, Singapore, Taiwan, and Thailand. METHODS: This cross-sectional observational study enrolled adults (age ≥18 years) presenting to general practitioners (GP) or specialists for physician-diagnosed AR, asthma, COPD, or rhinosinusitis...
June 6, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29873044/chronic-obstructive-pulmonary-disease-tunisian-society-of-respiratory-diseases-and-allergology-guidelines
#17
Samy Kammoun, Abdelaziz Hayouni, Hedia Ghrairi, Hajer Racil, Naceur Rouetbi, Abdelhamid Garrouche, Imen Gargouri, Ridha Ben Younes, Anis Maatallah, Souhaiel Slama, Mohamed Smaoui, Faiçal Bali, Fatma Tritar, Mohamed Ridha Charfi
No abstract text is available yet for this article.
August 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29871630/a-candidate-gene-identification-strategy-utilizing-mouse-to-human-big-data-mining-3r-tenet-in-copd-genetic-research
#18
Sangeetha Vishweswaraiah, Leema George, Natarajan Purushothaman, Koustav Ganguly
BACKGROUND: Early life impairments leading to lower lung function by adulthood are considered as risk factors for chronic obstructive pulmonary disease (COPD). Recently, we compared the lung transcriptomic profile between two mouse strains with extreme total lung capacities to identify plausible pulmonary function determining genes using microarray analysis (GSE80078). Advancement of high-throughput techniques like deep sequencing (eg. RNA-seq) and microarray have resulted in an explosion of genomic data in the online public repositories which however remains under-exploited...
June 6, 2018: Respiratory Research
https://www.readbyqxmd.com/read/29870550/utility-of-serum-aspergillus-galactomannan-antigen-to-evaluate-the-risk-of-severe-acute-exacerbation-in-chronic-obstructive-pulmonary-disease
#19
Katsuhiro Yoshimura, Yuzo Suzuki, Yusuke Inoue, Koji Nishimoto, Kazutaka Mori, Masato Karayama, Hironao Hozumi, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Naoki Inui, Koushi Yokomura, Shiro Imokawa, Takafumi Suda
BACKGROUND: Recent studies have shown that the microbiome, namely Aspergillus species, play a previously unrecognized role in both stable and exacerbated chronic obstructive pulmonary disease (COPD). Galactomannan is a major component of the Aspergillus cell wall that has been widely used as a diagnostic marker. OBJECTIVES: To explore whether serum levels of Aspergillus-galactomannan antigen could be used to evaluate the risk of severe acute exacerbation of COPD (AE-COPD)...
2018: PloS One
https://www.readbyqxmd.com/read/29869957/interstitial-features-at-chest-ct-enhance-the-deleterious-effects-of-emphysema-in-the-copdgene-cohort
#20
Samuel Y Ash, Rola Harmouche, James C Ross, Alejandro A Diaz, Farbod N Rahaghi, Gonzalo Vegas Sanchez-Ferrero, Rachel K Putman, Gary M Hunninghake, Jorge Onieva Onieva, Fernando J Martinez, Augustine M Choi, Russell P Bowler, David A Lynch, Hiroto Hatabu, Surya P Bhatt, Mark T Dransfield, J Michael Wells, Ivan O Rosas, Raul San Jose Estepar, George R Washko
Purpose To determine if interstitial features at chest CT enhance the effect of emphysema on clinical disease severity in smokers without clinical pulmonary fibrosis. Materials and Methods In this retrospective cohort study, an objective CT analysis tool was used to measure interstitial features (reticular changes, honeycombing, centrilobular nodules, linear scar, nodular changes, subpleural lines, and ground-glass opacities) and emphysema in 8266 participants in a study of chronic obstructive pulmonary disease (COPD) called COPDGene (recruited between October 2006 and January 2011)...
June 5, 2018: Radiology
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