Pooja Singh, Anand Narain Srivastava, Rolee Sharma, Saboor Mateen, Bharat Shukla, Alok Singh, Siddhartha Chandel
Background: Circulating miRNAs (miRs) in the biofluids such as serum and plasma act as potential biomarkers for early diagnosis, treatment and prognosis. In the present study, an attempt made to see the expression of miR-21 in serum of 20 cases of Oral sub-mucous fibrosis (OSMF), 20 cases of Oral squamous cell carcinoma and 40 healthy volunteers. The expression of miR-21 was evaluated in relation to different demographical and clinicopathological features such as sex, tobacco, pan-masala, alcohol, smoking and clinical staging respectively with an aim to identify correlation with oral pre-cancer and cancer stages...
April 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP