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https://www.readbyqxmd.com/read/28734275/low-level-of-autophagy-related-gene-10-atg10-expression-in-the-6-hydroxydopamine-rat-model-of-parkinson-s-disease
#1
Marzieh Shams Nooraei, Ali Noori-Zadeh, Shahram Darabi, Farzad Rajaei, Zohreh Golmohammadi, Hojjat Allah Abbaszadeh
Background: Autophagy is a mechanism disassembling the damaged organelles from the cell. This study attempted to examine the expression of several autophagy-related genes in Parkinson’s disease (PD) rat model. Methods: The male Wistar rats were divided into three groups as control, sham, and lesion. In the latter group, the PD rat model was induced by the injection of 6-hydroxydopamine in the striatum.The behavioral test was conducted one (baseline) and four weeks after the surgery through apomorphine hydrochloride...
July 23, 2017: Iranian Biomedical Journal
https://www.readbyqxmd.com/read/28734270/a-case-study-of-an-unknown-mass-grave-hostages-killed-70-years-ago-by-a-nazi-firing-squad-identified-thanks-to-genetics
#2
Andrzej Ossowski, Marta Diepenbroek, Marcin Zwolski, Adam Falis, Maria Wróbel, Milena Bykowska-Witowska, Grażyna Zielińska, Maria Szargut, Tomasz Kupiec
Almost 6 million people died in Poland during the Nazi occupation and about 570 thousand during the Soviet occupation. But the end of the war was not the end of the trauma. Historians estimate that at least 30 thousand people were killed during the Stalinist regime in Poland. In 2012 the Institute of National Remembrance started to search for hidden burials of victims of communism. Many exhumations were carried out under the project. One of them took place in Białystok, eastern Poland. According to information gathered by local historians, a detention centre in the heart of city was the place of secret burials of victims of the communist regime...
July 8, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28734263/study-of-the-influencing-factors-of-the-blood-levels-of-toxic-elements-in-africans-from-16-countries
#3
Luis Alberto Henríquez-Hernández, Octavio P Luzardo, Luis D Boada, Cristina Carranza, José Luis Pérez Arellano, Ana González-Antuña, Maira Almeida-González, Carlos Barry-Rodríguez, Manuel Zumbado, María Camacho
Africa's economy is growing faster than any other continent and it has been estimated that the middle class in Africa now exceeds 350 million people. This has meant a parallel increase in the importation of consumer goods and in the implementation of communication and information technologies (ICT), but also in the generation of large quantities of e-waste. However, inadequate infrastructure development remains a major constraint to the continent's economic growth and these highly toxic residues are not always adequately managed...
July 19, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28734249/nitrogen-losses-and-greenhouse-gas-emissions-under-different-n-and-water-management-in-a-subtropical-double-season-rice-cropping-system
#4
Kaiming Liang, Xuhua Zhong, Nongrong Huang, Rubenito M Lampayan, Yanzhuo Liu, Junfeng Pan, Bilin Peng, Xiangyu Hu, Youqiang Fu
Nitrogen non-point pollution and greenhouse gas (GHG) emission are major challenges in rice production. This study examined options for both economic and environmental sustainability through optimizing water and N management. Field experiments were conducted to examine the crop yields, N use efficiency (NUE), greenhouse gas emissions, N losses under different N and water management. There were four treatments: zero N input with farmer's water management (N0), farmer's N and water management (FP), optimized N management with farmer's water management (OPTN) and optimized N management with alternate wetting and drying irrigation (OPTN+AWD)...
July 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28734239/stigma-resistance-and-its-association-with-internalised-stigma-and-psychosocial-outcomes-among-psychiatric-outpatients
#5
Ying Wen Lau, Louisa Picco, Shirlene Pang, Anitha Jeyagurunathan, Pratika Satghare, Siow Ann Chong, Mythily Subramaniam
Studies have suggested that stigma resistance plays an important role in the recovery from mental illness. However, there has been limited research in Asian countries that has examined the benefits of stigma resistance among the mentally ill in Asian populations. Hence, this study aimed to assess the prevalence of stigma resistance and establish the socio-demographic correlates of stigma resistance, as well as its association with internalised stigma and psychosocial outcomes among a multi-ethnic population of 280 outpatients with obsessive compulsive disorder (OCD), schizophrenia, depressive disorders and anxiety disorders in Singapore...
July 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28734232/the-impact-of-a-faculty-training-program-on-inclusive-education-and-disability
#6
Anabel Moriña, Rafael Carballo
This paper describes the knowledge gained by 20 faculty members following their participation in a training program on inclusive education and disability. The study, which was conducted at an university in Spain, aimed to design, implement and evaluate a program for training faculty members to respond in an inclusive manner to the needs of students with disabilities. An initial, formative and summative qualitative evaluation was carried out and four instruments were used for collecting the data: group and individual interviews, written open-ended questionnaires and observations...
June 23, 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28734230/simultaneous-scanning-tunneling-microscopy-and-synchrotron-x-ray-measurements-in-a-gas-environment
#7
Rik V Mom, Willem G Onderwaater, Marcel J Rost, Maciej Jankowski, Sabine Wenzel, Leon Jacobse, Paul F A Alkemade, Vincent Vandalon, Matthijs A van Spronsen, Matthijs van Weeren, Bert Crama, Peter van der Tuijn, Roberto Felici, Wilhelmus M M Kessels, Francesco Carlà, Joost W M Frenken, Irene M N Groot
A combined X-ray and scanning tunneling microscopy (STM) instrument is presented that enables the local detection of X-ray absorption on surfaces in a gas environment. To suppress the collection of ion currents generated in the gas phase, coaxially shielded STM tips were used. The conductive outer shield of the coaxial tips can be biased to deflect ions away from the tip core. When tunneling, the X-ray-induced current is separated from the regular, 'topographic' tunneling current using a novel high-speed separation scheme...
July 14, 2017: Ultramicroscopy
https://www.readbyqxmd.com/read/28734219/acute-toxicity-of-cadmium-in-anisops-sardeus-heteroptera-notonectidae-effects-on-adult-and-nymphal-survival-and-swimming-behavior
#8
Chongtham Memtombi Chanu, Susmita Gupta, Abhik Gupta
Adult female and male, and final instar nymph of Anisops sardeus (Heteroptera: Notonectidae) were exposed to graded concentrations of cadmium in 96h static-with-renewal acute toxicity tests, which were conducted in dry (March) and wet (May-June) seasons. The 96h LC50 values for instar V nymph, adult female and male were found to be 0.9, 0.59 and 0.51mgL(-1) Cd, respectively, in wet season, while these were 26.7 and 20.2mgL(-1) Cd for adult female and male, respectively, in dry season. Adult males were most sensitive to Cd, followed by females in both seasons, while highest tolerance in wet season was observed in instar V nymph...
July 19, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28734218/the-evaluation-of-polycyclic-aromatic-hydrocarbons-pahs-biodegradation-kinetics-in-soil-amended-with-organic-fertilizers-and-bulking-agents
#9
Dariusz Włóka, Agnieszka Placek, Agnieszka Rorat, Marzena Smol, Małgorzata Kacprzak
The aim of this study was to investigate the polycyclic aromatic hydrocarbons (PAHs) biodegradation kinetics in soils fertilized with organic amendments (sewage sludge, compost), bulking agents (mineral sorbent, silicon dioxide in form of nano powder), and novel compositions of those materials. The scope of conducted works includes a cyclic CO2 production measurements and the determinations of PAHs content in soil samples, before and after 3-months of incubation. Obtained results show that the use of both type of organic fertilizers have a positive effect on the PAHs removal from soil...
July 19, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28734214/effects-of-damming-on-the-distribution-and-methylation-of-mercury-in-wujiang-river-southwest-china
#10
Lei Zhao, Yanna Guo, Bo Meng, Heng Yao, Xinbin Feng
Newly built reservoirs are regarded as sensitive ecosystem for mercury (Hg) methylation. A comprehensive study was conducted to understand the influence of damming on the distribution and methylation of Hg within a river-reservoir ecosystem in Wujiang River Basin (WRB), Southwest China. Hg species in inflow-outflow rivers of six cascade reservoirs were analyzed each month during 2006. Mean concentrations of total Hg (THg) and methylmercury (MeHg) in river water in WRB were 3.41 ± 1.98 ng L(-1) and 0.15 ± 0...
July 17, 2017: Chemosphere
https://www.readbyqxmd.com/read/28734201/modification-of-chemical-properties-cu-fractionation-and-enzymatic-activities-in-an-acid-vineyard-soil-amended-with-winery-wastes-a-field-study
#11
Isabel Rodríguez-Salgado, Paula Pérez-Rodríguez, Antía Gómez-Armesto, Montserrat Díaz-Raviña, Juan Carlos Nóvoa-Muñoz, Manuel Arias-Estévez, David Fernández-Calviño
The effects of adding two winery wastes, perlite waste (PW) and bentonite waste (BW), to an acid vineyard soil were assessed using some chemical and biological soil properties in a field study that lasted 18 months. The addition of PW (up to 81 Mg ha(-1)) had neither significant nor permanent effects on soil characteristics such as the pH, organic matter content or nutrient concentrations, the amounts of copper or zinc, or the electrical conductivity. Moreover, no persistent negative effects were found on the enzymatic activities after PW application...
July 19, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28734195/implementation-of-psychological-clinical-trials-in-epilepsy-review-and-guide
#12
REVIEW
Avani C Modi, Janelle Wagner, Aimee W Smith, Tanja S Kellermann, Rosa Michaelis
The International League Against Epilepsy (ILAE) Neuropsychiatry commission and United States Institute of Medicine report both identified cognitive and psychological comorbidities as a significant issue for individuals with epilepsy, with rates as high as 60%. However, there is a paucity of evidence-based treatments for many psychological conditions (e.g., learning disorders, cognitive disorders, behavioral disorders). Because of inherent challenges in the implementation of psychological therapy trials and specific considerations for the population with epilepsy, the focus of the current review was to provide guidance and recommendations to conduct psychological trials for individuals with epilepsy...
July 19, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28734191/evolutionary-dynamics-of-recent-peste-des-petits-ruminants-virus-epidemic-in-china-during-2013-2014
#13
Jingyue Bao, Qinghua Wang, Lin Li, Chunju Liu, Zhicheng Zhang, Jinming Li, Shujuan Wang, Xiaodong Wu, Zhiliang Wang
Peste des petits ruminants virus (PPRV) causes a highly contagious disease, peste des petits ruminants (PPR), in sheep and goats which has been considered as a serious threat to the local economy in Africa and Asia. However, the in-depth evolutionary dynamics of PPRV during an epidemic is not well understood. We conducted phylogenetic analysis on genomic sequences of 25 PPRV strains from China 2013-2014 outbreaks. All these strains clustered into a novel clade in lineage 4. An evolutionary rate of 2.61 × 10(-6) nucleotide substitutions per site per day was estimated, dating the most recent common ancestor of PPRV China 2013-2014 strains to early August 2013...
July 19, 2017: Virology
https://www.readbyqxmd.com/read/28734184/an-empirical-review-of-potential-mediators-and-mechanisms-of-prolonged-exposure-therapy
#14
REVIEW
Andrew A Cooper, Erin G Clifton, Norah C Feeny
Prolonged exposure (PE) is an empirically-supported treatment for posttraumatic stress disorder (PTSD), but the precise mechanism(s) by which PE promotes symptom change are not well established. Understanding how PE works is critical to improving clinical outcomes, advancing dissemination efforts, and enhancing transdiagnostic models of psychopathology. However, mechanisms research conducted in clinical treatment settings is complex, and findings may be difficult to interpret without appropriate context. This is the first review of potential mechanisms of PE to provide such context, by rigorously evaluating empirical findings in line with essential criteria for effective research on mechanisms (or mediators)...
July 11, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/28734170/web-based-physical-activity-interventions-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#15
REVIEW
Leila Jahangiry, Mahdieh Abbasalizad Farhangi, Sakineh Shab-Bidar, Fatemeh Rezaei, T Pashaei
OBJECTIVES: It was estimated that approximately 60% of the world's population is classified as inactive or insufficiently active. This meta-analysis investigated the effect of web-based interventions on different types of physical activity (PA) measurements in general population and potential moderating variables. STUDY DESIGN: PubMed, CINAHL, EBSCOhost, PsycINFO, Scopus, Ovid, and ScienceDirect literature searches were conducted to identify studies investigating the effect of web-based interventions on PA...
July 19, 2017: Public Health
https://www.readbyqxmd.com/read/28734133/physicians-self-reported-practice-behaviour-regarding-fertility-related-discussions-in-paediatric-oncology-in-sweden
#16
G M Armuand, J Nilsson, K A Rodriguez-Wallberg, J Malmros, J Arvidson, C Lampic, L Wettergren
OBJECTIVE: The aim of this study was to investigate practice behaviours of Swedish physicians with regard to discussing the impact of cancer treatment on fertility with paediatric oncology patients and their parents, and to identify factors associated with such discussions. METHODS: A cross-sectional survey study was conducted targeting all physicians in Sweden working in paediatric oncology care settings. Participants responded to a questionnaire measuring practice behaviour, attitudes, barriers, and confidence in knowledge...
July 22, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28734131/changes-in-health-related-quality-of-life-in-older-candidates-waiting-for-kidney-transplantation
#17
Kjersti Lønning, Karsten Midtvedt, Tomm Bernklev, Cathrine Brunborg, Marit Helen Andersen, Nanna von der Lippe, Anna V Reisaeter, Pål-Dag Line, Anders Hartmann, Kristian Heldal
AIM: There is limited available knowledge regarding health-related quality of life (HRQoL) in older patients with chronic kidney disease. We aimed to describe HRQoL in renal transplant candidates 65 years or older at transplant acceptance, and during the first year on the waiting list.. METHODS: A nationwide prospective observational study in Norway was conducted. HRQoL was evaluated at baseline (wait listing) and after 6 and 12 months using the patient self-reported Kidney Disease and Quality of Life Short form version 1...
July 22, 2017: Nephrology
https://www.readbyqxmd.com/read/28734125/a-systematic-review-and-meta-analysis-of-cold-in-situ-perfusion-and-preservation-of-the-hepatic-allograft-working-towards-a-unified-approach
#18
REVIEW
Ahmer M Hameed, Jerome M Laurence, Vincent W T Lam, Henry C Pleass, Wayne J Hawthorne
BACKGROUND: The efficacy of cold in situ perfusion and static storage of the liver is one possible determinant of transplantation outcomes. The aim of this study was to determine whether there is evidence to substantiate a preference for a particular perfusion route (aortic or dual) or perfusion/preservation solution in donation after brain-death (DBD) liver transplantation. METHODS: The Embase, Medline and Cochrane databases were utilized (1980-2017). Random effects modeling was used to estimate effects on transplantation outcomes based upon (i) aortic or dual in situ perfusion, and (ii) the use of University of Wisconsin (UW), histidine-tryptophan-ketoglutarate (HTK), Celsior and/or Institut Georges Lopez-1 (IGL-1) for perfusion/preservation...
July 22, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28734121/the-impact-of-chronic-psychiatric-disorders-on-cognitive-decline
#19
R Villeneuve, C Blanchard, L Rullier, N Raoux, V Bergua, J-F Dartigues, K Pérès, H Amieva
OBJECTIVES: Based on seemingly contradictory results in the existing literature, the objective of our study was to investigate whether older individuals suffering from chronic psychiatric disorders show a more rapid decline in cognitive performances than their non-psychiatric counterparts, or if the pattern of decline through older age is similar in both groups. METHOD: A total of 820 older adults were selected from the Ageing Multidisciplinary Investigation (AMI) cohort study, which studies health-related issues of people over 65 years old living in rural areas...
July 22, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28734119/a-systematic-review-of-patient-oncofertility-support-needs-in-reproductive-cancer-patients-aged-14-to-45-years-of-age
#20
REVIEW
S Logan, J Perz, J M Ussher, M Peate, A Anazodo
OBJECTIVE: Decline in fertility potential brought about by a cancer diagnosis or cancer treatment is one of the biggest impacts to cancer patients' long term quality of life. As such, the current manuscript aimed to systematically review the literature on oncofertility support needs for cancer patients of a reproductive age (14-45 years of age). METHODS: A systematic review of the literature was conducted in May 2016 through the searching of electronic databases Medline, EMBASE, PSYCH Info, Web of Science and SCOPUS, alongside the screening of relevant reference lists...
July 22, 2017: Psycho-oncology
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