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chronic pharyngitis

Toshiaki Kikuchi, Ryoukichi Ikeda, Hidetoshi Oshima, Iori Takata, Tetsuaki Kawase, Takeshi Oshima, Yukio Katori, Toshimitsu Kobayashi
CONCLUSIONS: Trans-tympanic plugging of the Eustachian tube (ET) with the silicone plug (Kobayashi Plug) induced long-term effectiveness for over 80% of chronic and severe patulous ET (PET) patients. The New Kobayashi Plug was more effective with fewer complication of plug descent to the pharyngeal orifice. OBJECTIVE: To investigate the effectiveness and complications of trans-tympanic plugging of the ET using a Kobayashi Plug for chronic PET. METHOD: Trans-tympanic plugging of the ET using the Kobayashi Plug was performed for 252 ears of 191 patients...
September 26, 2016: Acta Oto-laryngologica
Pia Järvenpää, Taru Ilmarinen, Ahmed Geneid, Petra Pietarinen, Teemu J Kinnari, Heikki Rihkanen, Johanna Ruohoalho, Mari Markkanen-Leppänen, Leif Bäck, Perttu Arkkila, Leena-Maija Aaltonen
Globus patients with normal ear, nose, and throat (ENT) status are a diagnostic challenge. The symptom may be long lasting and cause concern about malignancy, leading to possibly unnecessary further investigation. The aim of the study was to assess whether radiological examinations are useful in globus diagnostics, how often patients suffer from persistent globus, and whether globus patients with normal ENT status develop a malignancy during a follow-up. We reviewed medical records of all 76 globus patients referred to Helsinki University Hospital, Department of Otorhinolaryngology-Head and Neck Surgery in 2009...
September 17, 2016: European Archives of Oto-rhino-laryngology
P Graff, V Woisard, S Racadot, J Thariat, Y Pointreau
Radio-induced pharyngolaryngeal chronic disorders may challenge the quality of life of head and neck cancer long survivors. Many anatomic structures have been identified as potentially impaired by irradiation and responsible for laryngeal edema, dysphonia and dysphagia. Some dose constraints might be plausible such as keeping the mean dose to the pharyngeal constrictor muscles under 50 to 55Gy, the mean dose to the supra-glottic larynx under 40 to 45Gy and, if feasible, the mean dose to the glottic larynx under 20Gy...
October 2016: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
Diane Wenhua Chen, Jan S Lewin, Li Xu, Stephen Y Lai, G Brandon Gunn, Clifton David Fuller, Abdallah S R Mohamed, Aasheesh Kanwar, Erich M Sturgis, Katherine A Hutcheson
OBJECTIVES: To evaluate feeding tube utilization in patients with salivary gland malignancies (SGMs). STUDY DESIGN: Case series with planned data collection. SETTING: The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. SUBJECTS AND METHODS: Patients (N = 287) were sampled from an epidemiologic SGM registry during a 12-year period. Feeding tube history was retrospectively reviewed. Patients with outside locoregional therapy or palliative treatment were excluded...
August 30, 2016: Otolaryngology—Head and Neck Surgery
Evan C Cumpston, Joel H Blumin, Jonathan M Bock
OBJECTIVES: Minimal data exist to define the use of contemporary dual pH with multichannel intraluminal impedance (MII) probes integrating both pharyngeal acid and impedance sensors to evaluate laryngopharyngeal reflux (LPR) symptoms in a laryngology clinic population. This study was performed to review a series of patients tested with dual pH-MII for suspected LPR symptoms and to analyze pH-MII data findings for this patient cohort. STUDY DESIGN: Case series with planned data collection...
August 23, 2016: Otolaryngology—Head and Neck Surgery
Zahra Heidari, Ammar H Keshteli, Awat Feizi, Hamid Afshar, Peyman Adibi
Background/Aims: Somatization may influence persistence and severity of symptoms in gastrointestinal diseases. Some studies suggest that somatization is associated with chronic uninvestigated dyspepsia (CUD); however, the association is unclear. We aimed to determine the association between the profiles of somatic complaints with CUD and its symptoms. Methods: In a cross-sectional study conducted on 4763 Iranian adults, somatic complaints were assessed using a comprehensive 31-items questionnaire...
August 9, 2016: Journal of Neurogastroenterology and Motility
Jinwook Lee, Niluka D Gunawardhana, Sungil Jang, Yun Hui Choi, Rasika P Illeperuma, Aeryun Kim, Hanfu Su, Youngmin A Hong, Ji-Hye Kim, Jinmoon Kim, Da-Woon Jung, In-Ho Cha, Eun-Jung Bak, Jeong-Heon Cha
Areca nut (AN) chewing is a habit in many countries in Central, Southern, and Southeast Asia. It is strongly associated with the occurrence of oral, pharyngeal, and esophageal cancer as well as systemic inflammation. However, the association between AN intake and the development of gastric lesions has not yet been identified. The aim of this study was to investigate the effect of AN on gastric diseases using a mouse model for Helicobacter pylori infection. We studied four groups of mice: those fed a normal diet (ND), those fed a diet containing 2...
July 19, 2016: Journal of Microbiology and Biotechnology
C Dulery, A Lechot, S Roman, P-L Bastier, D Stoll, L de Gabory, F Zerbib
BACKGROUND: The role of gastroesophageal reflux in chronic laryngeal symptoms is difficult to establish. The aim of this study was to characterize pharyngeal and esophageal pH-impedance reflux patterns in a group of patients with suspected laryngopharyngeal reflux and to determine predictive factors of response to proton pump inhibitors. METHODS: Patients with chronic pharyngolaryngeal symptoms were evaluated with a symptom score questionnaire, laryngoscopy, and 24-hour pharyngeal and esophageal pH-impedance monitoring at baseline and after 8-week treatment with esomeprazole 40 mg b...
July 18, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
Chenguang Wang, Wei Xiong, Sathyanarayana Reddy Perumalla, Jianguo Fang, Changquan Calvin Sun
Dihydromyricetin (DMY) is a natural flavanol compound isolated from a traditional Chinese medicine, Ampelopsis grossedentata. Despite that optically pure (+)DMY is desired for treating chronic pharyngitis and alcohol use disorders, only DMY racemate is commercially available due to prolonged exposure time to high temperature and the presence of metal ions during industrial extraction, which cause racemization of the homochiral (+)DMY. We have developed an extraction method for successfully obtain optically pure (+)DMY...
September 10, 2016: International Journal of Pharmaceutics
Stian Wærsted, Thomas Dethloff
This case report describes an aberrant course of the internal carotid artery (ICA) in a patient presenting with symptoms of globus sensation, mild chronic cough and occasional aspiration. Clinically, a pulsating oro-hypopharyngeal tumour could only be visualized by fiberlaryngoscopy. A CT-scan showed a tortuous ICA protruding into the lateral and posterior pharyngeal wall. This condition may need treatment in itself, and it can lead to co-morbidity and serious surgical complications in undiagnosed patients...
July 11, 2016: Ugeskrift for Laeger
Lin Shi, Haolin Wang, Lai Wei, Zhijun Hong, Mingyu Wang, Zhiqiang Wang
CONCLUSIONS: Pharyngeal constrictor muscle injury and fatty changes may play important roles in the pathogenesis and progression of OSAHS. OBJECTIVE: Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a respiratory disorder caused by upper airway obstruction during sleep. The primary objectives of this study were to determine the ultrastructural characteristics of the pharyngeal constrictor muscle in patients with OSAHS. METHODS: A pharyngeal constrictor muscle specimen was collected from all subjects...
July 11, 2016: Acta Oto-laryngologica
Rajendra Prasad Takhar, Motilal Bunkar, Shubhra Jain, Sanjay Ghabale
Tracheal diverticulum (TD) defined as a typical benign out-pouching of the tracheal wall due to structural weakness, congenital or acquired in origin, resulting in paratracheal air cysts. It is rarely diagnosed in clinical practice with only limited reports in the literature. Most cases found incidentally in the postmortem examination and located on the right side. Uncomplicated TDs are usually asymptomatic and when symptoms have occurred, they usually present with non-specific symptoms like pharyngeal discomfort, cough, dyspnea, and recurrent respiratory infection due to either the compression of adjacent organs or secondary bacterial infection...
March 2016: Tüberküloz Ve Toraks
Thomas M Atkinson, Sean J Ryan, Antonia V Bennett, Angela M Stover, Rebecca M Saracino, Lauren J Rogak, Sarah T Jewell, Konstantina Matsoukas, Yuelin Li, Ethan Basch
PURPOSE: Symptomatic adverse events (AEs) are monitored by clinicians as part of all US-based clinical trials in cancer via the U.S. National Cancer Institute's Common Terminology Criteria for Adverse Events (CTCAE) for the purposes of ensuring patient safety. Recently, there has been a charge toward capturing the patient perspective for those AEs amenable to patient self-reporting via patient-reported outcomes (PRO). The aim of this review was to summarize the empirically reported association between analogous CTCAE and PRO ratings...
August 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
A Jama-Kmiecik, M Frej-Mądrzak, J Sarowska, I Choroszy-Król
The aim of the present study was to determine the results of typical and atypical bacteria microbiological tests in patients with symptoms of chronic cough. We investigated 230 outpatients aged from 1 to 83 years (112 female, 72 male, and 46 children) who were free of any respiratory tract infection at the time of study. The material for the investigation consisted of pharyngeal swabs. Two hundred and thirty pharyngeal swabs were examined for Chlamydia pneumoniae antigen and for typical pathogens each. Chlamydia pneumoniae antigen was detected using an indirect immunofluorescence test and classical microbiological culture was used for the detection of typical bacteria...
2016: Advances in Experimental Medicine and Biology
Qi Kang, Gang Chen, Jun Lu, Huijiong Yu
AIMS: There have been few studies on the disparities within the population with disabilities, especially in China. The aim of this study was to evaluate the differences in some health conditions among people with different types of disabilities in Shanghai. METHODS: This study was conducted using data from the Shanghai Disabled Persons' Rehabilitation Comprehensive Information Platform. The records of 31,082 persons with disabilities who had undergone professional health examination were analyzed, and the prevalence and number of five diseases and five risk factors were examined...
2016: PloS One
Anna Górecka-Tuteja, Izabela Jastrzębska, Jacek Składzień, Krzysztof Fyderek
BACKGROUND/AIMS: To evaluate the characteristic properties of laryngopharyngeal reflux (LPR) and gastroesophageal reflux (GER) in children with otitis media with effusion (OME) using 24-hour multichannel intraluminal impedance combined with dual-probe (pharyngeal and esophageal) pH-metry. METHODS: Children aged 7-10 years of age with OME underwent 24-hour multichannel intraluminal impedance pH-metry. The upper pH sensor was situated 1 cm above the upper esophageal sphincter, and the lower pH sensor was placed 3-5 cm above the lower esophageal sphincter...
July 30, 2016: Journal of Neurogastroenterology and Motility
W Y Liu, Q Yu, H M Yue, J B Zhang, L Li, X Y Wang, J M Hu, T Feng, J Y Pu, X Bai
OBJECTIVE: To explore the distribution characteristics of etiology and clinical feature of chronic cough in Lanzhou. METHODS: Based on the guidelines of the diagnostic process of chronic cough in China, data of medical history and physical examinations were collected, and chest X-ray, pulmonary function plus airway hyperresponsiveness, induced sputum eosinophils, sinus X-ray or CT, 24 h esophageal pH monitoring, chest high-resolution CT and bronchoscopy were performed accordingly for outpatients with chronic cough...
May 2016: Chinese Journal of Tuberculosis and Respiratory Diseases
A Mohapatra, T Khan, J Diaz, R Brasington, L P Zebala
BACKGROUND: Context: No previous cases of atlantoaxial instability due to granulomatosis with polyangiitis have been reported. PURPOSE: To report a case of granulomatosis polyangiitis causing atlantoaxial instability. STUDY DESIGN: Case report. PATIENT SAMPLE: A 45-year-old woman. OUTCOME MEASURES: Resolution of the patient's pain and atlantoaxial instability. METHODS: This is a 45-year-old Caucasian woman with a large ulcerative lesion in her oropharynx...
May 11, 2016: Spine Journal: Official Journal of the North American Spine Society
Stefan Weinschenk, Markus W Hollmann, Richard Göllner, Susanne Picardi, Thomas Strowitzki, Leon Diehl, Lorenz Hotz, Thomas Meuser
BACKGROUND: Neck pain is a frequent reason for seeking medical advice. Neuroanatomical findings suggest a close connection between the pharynx and the trapezius region. Irritation of the pharynx may induce tenderness of this area. Specific tender points, called neck reflex points (NRPs), can be identified here with high reproducibility. We hypothesized that therapeutic local anesthesia (TLA; or neural therapy, NT) in the pharyngeal region can reduce tenderness in patients with therapy-resistant neck pain...
2016: Forschende Komplementärmedizin, Research in Complementary Medicine
Aintzane Urbizu, Alex Ferré, Maria-Antonia Poca, Alex Rovira, Juan Sahuquillo, Bryn A Martin, Alfons Macaya
OBJECTIVE Traditionally, Chiari malformation Type I has been related to downward herniation of the cerebellar tonsils as a consequence of an underdeveloped posterior cranial fossa. Although the common symptoms of Chiari malformation Type I are occipital headaches, cervical pain, dizziness, paresthesia, and sensory loss, patients often report symptoms related to pharyngeal dysfunction such as choking, regurgitation, dysphagia, aspiration, chronic cough, and sleep disorders. In addition, tracheal intubation is often difficult in these patients...
May 6, 2016: Journal of Neurosurgery
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