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https://www.readbyqxmd.com/read/29904930/250prevalence-of-self-reported-gingival-bleeding-in-a-representative-sample-of-the-brazilian-adolescent-population
#1
Paulo Nadanovsky, Ana Paula Pires Dos Santos, Katia Vergetti Bloch
AIM: To estimate the prevalence of self-reported gingival bleeding in a representative sample of 12-17-year-old Brazilian adolescents MATERIAL AND METHODS: Sociodemographic and oral health information were obtained through a self-administered questionnaire of the Study of Cardiovascular Risk Factors in Adolescents. The adolescents answered "yes" or "no" to the question "Do your gums bleed?" RESULTS: 74,589 of the 102,327 eligible adolescents answered the questionnaire and 18...
June 14, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29900092/infection-associated-hemophagocytic-lymphohistiocytosis-an-unusual-clinical-masquerader
#2
Awais Abbas, Mohammad Raza, Aamina Majid, Yumna Khalid, Syed Hamza Bin Waqar
Hemophagocytic lymphohistiocytosis (HLH) secondary to an infection is a great impersonator. It is caused by hyperimmune activation, which leads to a wide array of hematological abnormalities. If the disease is untreated, it is usually fatal. We report the case of a four-year-old girl who presented to our tertiary care hospital with high-grade fever, frequent loose stools, and bleeding from the lips and gums. Investigations showed pancytopenia, hyperferritinemia, hypofibrinogenemia, and hypertriglyceridemia whereas the bone marrow biopsy revealed hemophagocytosis with trilineage suppression...
April 12, 2018: Curēus
https://www.readbyqxmd.com/read/29896567/genomics-of-the-uncultivated-periodontitis-associated-bacterium-tannerella-sp-bu045-oral-taxon-808
#3
Clifford J Beall, Alisha G Campbell, Ann L Griffen, Mircea Podar, Eugene J Leys
Despite decades of research into the human oral microbiome, many species remain uncultivated. The technique of single-cell whole-genome amplification and sequencing provides a means of deriving genome sequences for species that can be informative on biological function and suggest pathways to cultivation. Tannerella forsythia has long been known to be highly associated with chronic periodontitis and to cause periodontitis-like symptoms in experimental animals, and Tannerella sp. BU045 (human oral taxon 808) is an uncultivated relative of this organism...
May 2018: MSystems
https://www.readbyqxmd.com/read/29881430/effects-of-dorema-ammoniacum-gum-on-neuronal-epileptiform-activity-induced-by-pentylenetetrazole
#4
Fatemeh Ghasemi, Hanieh Tamadon, Narges Hosseinmardi, Mahyar Janahmadi
Epilepsy is a chronic neurological disease which disrupts the neuronal electrical activity. One-third of patients are resistant to treatment with available antiepileptic agents. The use of herbal medicine for treating several diseases including epilepsy is on the rise. Therefore, further investigation is required to verify the safety and effectiveness of Phytomedicine in treating diseases. The current study is an attempt to elucidate the electrophysiological mechanism of the effect of Dorema ammoniacum gum on a cellular model of epilepsy, using intracellular recording method...
2018: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/29878310/more-evidence-that-gum-disease-increases-cancer-risk
#5
Carrie Printz
No abstract text is available yet for this article.
June 1, 2018: Cancer
https://www.readbyqxmd.com/read/29866790/the-influence-of-nicotine-on-lung-tumor-growth-cancer-chemotherapy-and-chemotherapy-induced-peripheral-neuropathy
#6
S Lauren Kyte, David A Gewirtz
Studies in animal models have suggested that nicotine, an agonist of nicotinic acetylcholine receptors (nAChRs), may have the potential to prevent and/or reverse the peripheral neuropathy induced by cancer chemotherapeutic drugs, such as paclitaxel and oxaliplatin. However, a large body of evidence suggests that nicotine may also stimulate lung tumor growth and/or interfere with the effectiveness of cancer chemotherapy. While the reported proliferative effects of nicotine are highly variable, the antagonism of antitumor drug efficacy is more consistent, although this latter effect has been demonstrated primarily in cell culture studies...
June 4, 2018: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/29862484/children-with-crohn-s-disease-frequently-consume-select-food-additives
#7
Dale Lee, C Kaiulani Swan, David Suskind, Ghassan Wahbeh, Jairam Vanamala, Robert N Baldassano, Mary B Leonard, Johanna W Lampe
OBJECTIVE: Certain food additives may promote the pathogenesis of Crohn's disease (CD), but thus far the evaluation of food additive exposures in humans has been limited. The objective of this study was to quantify food additive exposures in children with CD. METHODS: In a trial for bone health in CD, children were followed over 24 months with evaluation of disease characteristics, dietary intake, and body composition. At baseline, participants completed three 24-h dietary recalls...
June 4, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29860637/discovery-of-a-novel-periodontal-disease-associated-bacterium
#8
Pedro J Torres, John Thompson, Jeffrey S McLean, Scott T Kelley, Anna Edlund
One of the world's most common infectious disease, periodontitis (PD), derives from largely uncharacterized communities of oral bacteria growing as biofilms (a.k.a. plaque) on teeth and gum surfaces in periodontal pockets. Bacteria associated with periodontal disease trigger inflammatory responses in immune cells, which in later stages of the disease cause loss of both soft and hard tissue structures supporting teeth. Thus far, only a handful of bacteria have been characterized as infectious agents of PD. Although deep sequencing technologies, such as whole community shotgun sequencing have the potential to capture a detailed picture of highly complex bacterial communities in any given environment, we still lack major reference genomes for the oral microbiome associated with PD and other diseases...
June 2, 2018: Microbial Ecology
https://www.readbyqxmd.com/read/29859084/oral-health-knowledge-behavior-and-care-seeking-among-pregnant-and-recently-delivered-women-in-rural-nepal-a-qualitative-study
#9
A J Lubon, D J Erchick, S K Khatry, S C LeClerq, N K Agrawal, M A Reynolds, J Katz, L C Mullany
BACKGROUND: Oral health behavior and attitudes of pregnant women in low-income countries are rarely examined, yet should be considered when designing preventative or therapeutic studies to reduce burden of oral diseases. We aimed to understand dental care-seeking behavior, as well as oral health knowledge and attitudes of oral health among pregnant women in rural Nepal. METHODS: Semi-structured in-depth interviews (n = 16) and focus group discussions (3 groups, n = 23) were conducted among pregnant and recently-delivered women in Sarlahi, Nepal...
June 1, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29788415/association-of-e-cigarette-use-with-oral-health-a-population-based-cross-sectional-questionnaire-study
#10
Priyanka Huilgol, Surya P Bhatt, Niranjan Biligowda, Nicole C Wright, J Michael Wells
Background: The impact of daily or intermittent electronic cigarette (e-cigarette) use on oral health is unknown. Methods: We performed a cross-sectional analysis using the 2016 Behavioral Risk Factor Surveillance System data. Poor oral health was determined by the number of permanent teeth removed due to non-traumatic causes, and e-cigarette use determined by daily or intermittent use within 30 days prior to survey administration. We performed logistic regression analysis to test associations between e-cigarette use and oral health with adjustment for factors associated with poor oral health, survey clustering, strata and weight...
May 18, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/29785574/in-situ-nanostructured-hydrogel-of-resveratrol-for-brain-targeting-in-vitro-in-vivo-characterization
#11
Amarjitsing Rajput, Aditi Bariya, Ahmed Allam, Sarah Othman, Shital B Butani
The purpose of conducting the present research work was to develop resveratrol nanostructured in situ gel for the treatment of Alzheimer's disease. Resveratrol loaded lipid carrier was prepared by melt emulsification-probe sonication method, and the final product was evaluated for particle size (132 ± 11.90 nm), polydispersity index (0.209 ± 0.005), zeta potential (- 23 ± 3.79 mV), drug loading (9.26 ± 3.79%), and entrapment efficiency (74 ± 11.40%). Following incorporation of the resveratrol nanostructured lipid carrier in gellan gum and xanthan gum, in situ gel was formulated and characterized...
May 21, 2018: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/29753207/an-exploratory-study-of-the-factors-related-to-mouth-breathing-syndrome-in-primary-school-children
#12
Issei Saitoh, Emi Inada, Yasutaka Kaihara, Yukiko Nogami, Daisuke Murakami, Naoko Kubota, Kaoru Sakurai, Yoshito Shirazawa, Tadashi Sawami, Miyuki Goto, Maki Nosou, Katsuyuki Kozai, Haruaki Hayasaki, Youichi Yamasaki
OBJECTIVE: Mouth breathing syndrome (MBS) is defined as a set of signs and symptoms that may be completely or incompletely present in subjects who, for various reasons, replace the correct pattern of nasal breathing with an oral or mixed pattern. It is important to identify the relevant factors affecting MBS in order to diagnose its cause since breathing obstructions can result from multiple factors. The purpose of this study is to clarify the relevant factors and the interrelationships between factors affecting MBS among children...
March 26, 2018: Archives of Oral Biology
https://www.readbyqxmd.com/read/29716561/oral-health-knowledge-attitudes-and-care-practices-of-people-with-diabetes-a-systematic-review
#13
Prakash Poudel, Rhonda Griffiths, Vincent W Wong, Amit Arora, Jeff R Flack, Chee L Khoo, Ajesh George
BACKGROUND: People with uncontrolled diabetes are at greater risk for several oral health problems, particularly periodontal (gum) disease. Periodontal disease also impacts diabetes control. Good oral hygiene and regular dental visits are recommended to prevent and manage oral health problems. Several studies have been conducted to assess the oral health knowledge, attitudes, and practices of people with diabetes yet a review of these findings has not yet been undertaken. The aim of this systematic review was to synthesize current evidence on the knowledge, attitudes and practices of people with diabetes in relation to their oral health care...
May 2, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29706324/edible-coatings-incorporating-pomegranate-peel-extract-and-biocontrol-yeast-to-reduce-penicillium-digitatum-postharvest-decay-of-oranges
#14
Samira Kharchoufi, Lucia Parafati, Fabio Licciardello, Giuseppe Muratore, Mokthar Hamdi, Gabriella Cirvilleri, Cristina Restuccia
This study investigated the potential use of two edible coatings, chitosan (CH) and locust bean gum (LBG), which incorporated chemically characterized water pomegranate peel extract (WPPE) or methanol pomegranate peel extract (MPPE) and the biocontrol agent (BCA) Wickerhamomyces anomalus, to control the growth of Penicillium digitatum and to reduce the postharvest decay of oranges. CH and LBG including pomegranate peel extracts (PPEs) at different concentrations were tested in vitro against P. digitatum to determine their antifungal efficacy; at the same time, the tolerance of viable cells of W...
September 2018: Food Microbiology
https://www.readbyqxmd.com/read/29691333/community-development-between-porphyromonas-gingivalis-and-candida-albicans-mediated-by-inlj-and-als3
#15
Maryta N Sztukowska, Lindsay C Dutton, Christopher Delaney, Mark Ramsdale, Gordon Ramage, Howard F Jenkinson, Angela H Nobbs, Richard J Lamont
The pleiomorphic yeast Candida albicans is a significant pathogen in immunocompromised individuals. In the oral cavity, C. albicans is an inhabitant of polymicrobial communities, and interspecies interactions promote hyphal formation and biofilm formation. C. albicans colonizes the subgingival area, and the frequency of colonization increases in periodontal disease. In this study, we investigated the interactions between C. albicans and the periodontal pathogen Porphyromonas gingivalis C. albicans and P...
April 24, 2018: MBio
https://www.readbyqxmd.com/read/29670909/salivary-levels-of-il-6-and-il-17-could-be-an-indicator-of-disease-severity-in-patients-with-calculus-associated-chronic-periodontitis
#16
Husniah Batool, Ahmed Nadeem, Muhammad Kashif, Faheem Shahzad, Romeeza Tahir, Nadeem Afzal
Background/Purpose. Chronic periodontitis is an inflammatory disease of gums that causes loss of supporting structures of teeth, that is, gingiva, periodontal ligament, cementum, and alveolar bone. Levels of various cytokines in the serum, gingival tissues, and gingival crevicular fluid in patients with chronic periodontitis have been studied, but limited data are available on the level of cytokines in saliva. Therefore, a study was designed to determine levels of salivary IL-6 and IL-17 in patients with calculus associated chronic periodontitis...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29669437/development-of-hydrogels-oleogels-and-bigels-as-local-drug-delivery-systems-for-periodontitis
#17
Rania Hamed, Ala'a AbuRezeq, Ola Tarawneh
Periodontal disease is a chronic inflammation of gum and tissues that surround and support the teeth. Nonsteroidal anti-inflammatory drugs (NSAIDs) can be used in the treatment of periodontitis to ease swelling and inflammation. One approach of treating periodontitis is loading the NSAIDs in local drug delivery systems. Therefore, the objective of this study was to investigate the local delivery of the NSAIDs model drug ibuprofen to treat periodontitis using different types of gel formulations (hydrogel, oleogel, and bigel)...
May 7, 2018: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/29661189/origins-in-the-usa-in-the-1980s-of-the-warning-that-smokeless-tobacco-is-not-a-safe-alternative-to-cigarettes-a-historical-documents-based-assessment-with-implications-for-comparative-warnings-on-less-harmful-tobacco-nicotine-products
#18
Lynn T Kozlowski
BACKGROUND: Before the 1980s in the USA, smokeless tobacco carried no health warnings, was not judged to cause disease, and was a declining practice. In 1986, the federal government passed legislation requiring rotating warnings on "mouth cancer," "gum disease and tooth loss," and "This product is not a safe alternative to cigarettes." This paper explores the history of the establishment of these warnings with emphasis on the 'not a safe alternative' warning and the bases for claiming that smokeless was 'not safe' (absolute harm) versus 'not safer than cigarettes' (relative harm)...
April 16, 2018: Harm Reduction Journal
https://www.readbyqxmd.com/read/29659957/dietary-fermentable-fibers-attenuate-chronic-kidney-disease-in-mice-by-protecting-the-intestinal-barrier
#19
Tran Van Hung, Takuya Suzuki
Background: Chronic kidney disease (CKD) is a worldwide health problem. Although the pathogenesis of CKD is still unclear, recent studies suggest that systemic inflammation caused by a dysregulated microflora and an impaired intestinal barrier is involved in CKD development. Objective: We investigated the effects of the fermentable dietary fibers (DFs), unmodified guar gum (GG), and partially hydrolyzed GG (PHGG) (i.e., substances with distinct viscosity characteristics) on CKD development, with a particular focus on colonic tight junction (TJ) barriers in mice...
April 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29629329/relationship-between-physicochemical-properties-of-saliva-and-dental-caries-and-periodontal-status-among-female-teachers-living-in-central-iran
#20
Amene Hosseini-Yekani, Azadeh Nadjarzadeh, Mehrdad Vossoughi, Javad Zavvar Reza, Ali Golkari
Objectives: There are inconsistent data about the association between saliva properties, dental caries, and periodontal status. In this study, we tried to examine the association between dental caries and periodontal status with salivary viscosity, flow rate, pH, and buffering capacity in adults. Methods: In the present cross-sectional study, 450 female teachers were randomly selected from schools located in Yazd, Iran. Oral examinations were conducted, and unstimulated saliva samples were collected...
January 2018: Journal of International Society of Preventive & Community Dentistry
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