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Gum disease

Claude T Tagny, Pauline N Balôgôg, Francoise Boehlen, Dora Mbanya
In Cameroon, the Yaoundé Hemophilia Treatment Center (HTC) has so far recorded 121 cases of hemophilia and only 10 cases of von Willebrand disease (VWD). We report the case of a 16-year-old girl, living in the north of Cameroon. She presented with severe meno-metrorrhagia, which had increased drastically within the past 3 months, associated more recently by gum bleeding and epistaxis. The coagulation screen showed a prolonged bleeding time. The clinical profile of this young girl and the findings of less than 5% for von Willebrand factor (VWF):Ag and 10% for VWF Ristocetin cofactor suggests a type 3 VWD...
October 2016: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
Renato Quirino Ramos, João Luiz Bastos, Marco Aurélio Peres
Population-based studies assessing self-reported periodontal questions in low-income countries are lacking, and therefore we aimed to assess the accuracy of self-reported periodontal items in Brazil. One thousand one hundred and forty adults from Florianópolis, Brazil, had their periodontium clinically examined, and responded to the following self-reported items on periodontal conditions: Question (Q)1, Do you have any wobbly teeth?; Q2, Do your gums usually bleed?; and Q3, Has your dentist ever told you that you have gum disease? Periodontitis was defined as: a...
October 10, 2016: Brazilian Oral Research
Ana L Pérez-Balbuena, Juan C Ochoa-Tabares, Sandra Belalcazar-Rey, Cristian Urzúa-Salinas, Laura R Saucedo-Rodríguez, Regina Velasco-Ramos, Raúl G Suárez-Sánchez, Adolfo D Rodríguez-Carrizalez, Aldo A Oregón-Miranda
BACKGROUND: Dry eye disease (DED) is multifactorial, affecting 5-34 % of the global adult population and reducing quality of life. The artificial tears or lubricants are the therapy most used for the treatment of DED, due to their low side effect profile, which attempt to modify the properties of the tear film. The aim of the present study was to evaluate the clinical efficacy of a fixed combination of xanthan gum and chondroitin sulfate preservative free on the ocular surface of patients with dry eye disease during 60 days of intervention...
2016: BMC Ophthalmology
Jessica Walker, Julia Maria Imboeck, Joel Michael Walker, Amarnath Maitra, Hady Haririan, Xiaohui Rausch-Fan, Michael Dodds, Taichi Inui, Veronika Somoza
Inflammatory diseases of the periodontal tissues are known health problems worldwide. Therefore, anti-inflammatory active compounds are used in oral care products to reduce long-term inflammation. In addition to inducing inflammation, pathogen attack leads to an increased production of reactive oxygen species (ROS), which may lead to oxidative damage of macromolecules. Magnolia officinalis L. bark extract (MBE) has been shown to possess antioxidant and anti-inflammatory potential in vitro. In the present study, the influence of MBE-fortified chewing gum on the resistance against lipopolysaccharide (LPS)-induced inflammation and oxidative stress of oral epithelial cells was investigated in a four-armed parallel designed human intervention trial with 40 healthy volunteers...
2016: American Journal of Chinese Medicine
Priyanka Sehrawat, K K Shivlingesh, Bhuvandeep Gupta, Richa Anand, Abhinav Sharma, Monica Chaudhry
AIM: To assess the oral health knowledge, awareness and associated exercised practices of pre-school children's mothers in Greater Noida, India. SUBJECTS AND METHODS: The sampling frame for this study was chosen via convenient sampling. It comprised 598 mothers of children aged between 2 and 5 years, attending the paediatrics division of a government and four private hospitals in Greater Noida. A pre-tested questionnaire was distributed to the participants which comprised questions on the participant's sociodemographic characteristics and 23 statements regarding their knowledge, attitude and practices towards their child's oral health...
July 2016: Nigerian Postgraduate Medical Journal
Blerina Xhihani, Lori Rainchuso, Dianne Smallidge, Christine Dominick
Research indicates a high prevalence of oral disease among Albanians. There is a lack of evidence regarding oral health beliefs and practices among Albanian immigrants in the United States and abroad. This research seeks to better understand the oral health beliefs, attitudes, and practices among Albanian immigrants living in the United States. A descriptive study was employed with a purposive sample (n = 211) of Albanian adult immigrants. A cross-sectional validated questionnaire was provided in both English and Albanian, with a response rate of 66 %...
September 10, 2016: Journal of Community Health
Huabin Luo, Bei Wu
BACKGROUND: To assess the extent of self-awareness of gum disease among adults in the United States. METHODS: Data were from the 2009-2012 National Health and Nutrition Examination Survey. The outcome variable is self-awareness of gum disease. Multivariate logistic regression models were used to examine the relationship between self-awareness and clinically diagnosed periodontitis. The analytical sample included 6876 participants. RESULTS: Among those participants (30 years or older) who were classified as having periodontitis, 27% (95% confidence interval [CI], 24...
September 7, 2016: Journal of Public Health Management and Practice: JPHMP
Tomohisa Takagi, Yuji Naito, Yasuki Higashimura, Chihiro Ushiroda, Katsura Mizushima, Yuji Ohashi, Zenta Yasukawa, Makoto Ozeki, Makoto Tokunaga, Tsutomu Okubo, Kazuhiro Katada, Kazuhiro Kamada, Kazuhiko Uchiyama, Osamu Handa, Yoshito Itoh, Toshikazu Yoshikawa
Partially hydrolysed guar gum (PHGG), a water-soluble dietary fibre produced by the controlled partial enzymatic hydrolysis of guar gum beans, has various physiological roles. This study aimed to elucidate the beneficial effects of PHGG on colonic mucosal damage in a murine 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis model. Acute colitis was induced in male C57BL/6 mice with TNBS after 2 weeks of pre-feeding with PHGG (5 %). The colonic mucosal inflammation was evaluated using macroscopic damage scores, and neutrophil infiltration was assessed by measuring tissue-associated myeloperoxidase (MPO) activity in the colonic mucosa...
October 2016: British Journal of Nutrition
Soumyajit Biswas, Rupa Shaw, Sanjay Bala, Asis Mazumdar
ETHNOPHARMACOLOGICAL RELEVANCE: Medicinal Plant resources of forest origin are extensively used in India for various systems of medicine like Ayurveda, Unani, Homeopathy, Allopathy, Siddha and Ethnic etc. The tribal communities around the Kakrajhore forest in West Medinipur district of West Bengal have their own traditional knowledge based system of curing many diseases using the forest based plant resources similar to ayurveda. The forest comprises of one of the unique treasure and rich source of diversified ethno-botanical wealth and therefore extensive studies is required for proper documentation including ethnomedicinal knowledge of local tribes...
August 30, 2016: Journal of Ethnopharmacology
Justin Carlson, Trevor Gould, Joanne Slavin
BACKGROUND: Prebiotic dietary fibers resist digestion in the upper gastrointestinal tract and allow for stimulation of bacteria in the distal intestine and colon. Stimulation of bacteria among different individuals varies greatly, depending on a wide range of variables. OBJECTIVE: To determine the range of differences in response between individuals, a preclinical in vitro fermentation was conducted with six fecal donors. The primary objective was to compare the fecal microbiota of six individuals at baseline, 12 h and 24 h post-exposure to partially hydrolyzed guar gum (PHGG)...
August 30, 2016: Anaerobe
Hossein Ghaeminia, John Perry, Marloes E L Nienhuijs, Verena Toedtling, Marcia Tummers, Theo J M Hoppenreijs, Wil J M Van der Sanden, Theodorus G Mettes
BACKGROUND: Prophylactic removal of asymptomatic disease-free impacted wisdom teeth is surgical removal of wisdom teeth in the absence of symptoms and with no evidence of local disease. Impacted wisdom teeth may be associated with pathological changes, such as pericoronitis, root resorption, gum and alveolar bone disease (periodontitis), caries and the development of cysts and tumours. When surgical removal is carried out in older people, the risk of postoperative complications, pain and discomfort is increased...
2016: Cochrane Database of Systematic Reviews
Grace Joshy, Manish Arora, Rosemary J Korda, John Chalmers, Emily Banks
OBJECTIVE: To investigate the relationship between oral health and incident hospitalisation for ischaemic heart disease (IHD), heart failure (HF), ischaemic stroke and peripheral vascular disease (PVD) and all-cause mortality. DESIGN: Prospective population-based study of Australian men and women aged 45 years or older, who were recruited to the 45 and Up Study between January 2006 and April 2009; baseline questionnaire data were linked to hospitalisations and deaths up to December 2011...
2016: BMJ Open
Deeksha Singh, Uttam Singh Baghel, Anshoo Gautam, Dheeraj Singh Baghel, Divya Yadav, Jai Malik, Rakesh Yadav
ETHNOPHARMACOLOGICAL RELEVANCE: The genus Anogeissus (axlewood tree, ghatti tree, button tree and chewing stick tree) belongs to Combretaceae, includes eight species that are distributed in Asia and Africa. Plants are used as an ethnomedicine in Asia and Africa to treat various ailments like diabetes, fever, diarrhoea, dysentery, tuberculosis, wound healing, skin diseases (eczema, psoriasis), snake and scorpion venom. Based on the traditional knowledge, different phytochemical and pharmacological activities have been at the focus of research...
August 23, 2016: Journal of Ethnopharmacology
Jayanand Manjhi, Maneesh Gupta, Anvesha Sinha, Beena Rawat, Durg V Rai
Context • Osteoarthritis (OA) is one of the most prevalent chronic diseases of the musculoskeleton, causing functional disability among older adults. Management of OA includes conventional pharmacological treatments consisting primarily of nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen, physiotherapy, and surgical procedures. The medications are not ideal therapeutic agents; NSAIDs in particular can cause serious side effects. Objective • The study was conducted to investigate the effects of Balsamodendron mukul (BDM) gum resin extract on cartilage damage and microstructural changes in the subchondral bone of rats with papain-induced, osteoarthritic knee joints...
July 2016: Alternative Therapies in Health and Medicine
Benjamin O Emikpe, Victor O Oyebanji, Michael A Odeniyi, Adebayo M Salaam, Omolade A Oladele, Theophilus A Jarikre, Oluwole A Akinboade
BACKGROUND: Few studies have investigated the interaction of bioadhesives with biologic tissues for veterinary application. Hence, this study evaluates the mucoadhesive property and vaccine delivery properties of polymers from phytogenic origin. Gums from Cedrela odorata and Khaya senegalensis were harvested, purified, dried and compressed into 500 mg tablets individually and in combined ratios. The time taken for these tablets, placed on freshly excised (5 × 5 cm) trachea and duodenal tissues of cattle, chicken, pig, sheep and goat and fastened to the basket end of a tablet dissolution machine probe set at 50 rev/min in a phosphate buffer 6...
2016: SpringerPlus
Joshua Bakhsheshian, Justin K Scheer, Jeffrey L Gum, Richard Hostin, Virginie Lafage, Shay Bess, Themistocles S Protopsaltis, Douglas C Burton, Malla Kate Keefe, Robert A Hart, Gregory M Mundis, Christopher I Shaffrey, Frank Schwab, Justin S Smith, Christopher P Ames
OBJECTIVE Mental disease burden can have a significant impact on levels of disability and health-related quality of life (HRQOL) measures. Therefore, the authors investigated the significance of mental health status in adults with spinal deformity and poor physical function. METHODS A retrospective analysis of a prospective multicenter database of 365 adult spinal deformity (ASD) patients who had undergone surgical treatment was performed. Health-related QOL variables were examined preoperatively and at the 2-year postoperative follow-up...
August 19, 2016: Journal of Neurosurgery. Spine
Thanuja D K Herath, Richard P Darveau, Chaminda J Seneviratne, Cun-Yu Wang, Yu Wang, Lijian Jin
Periodontal (gum) disease is a highly prevalent infection and inflammation accounting for the majority of tooth loss in adult population worldwide. Porphyromonas gingivalis is a keystone periodontal pathogen and its lipopolysaccharide (PgLPS) acts as a major virulence attribute to the disease. Herein, we deciphered the overall host response of human gingival fibroblasts (HGFs) to two featured isoforms of tetra-acylated PgLPS1435/1449 and penta-acylated PgLPS1690 with reference to E. coli LPS through quantitative proteomics...
2016: Scientific Reports
Hadeel M Abbood, Juliane Hinz, George Cherukara, Tatiana V Macfarlane
Periodontal disease is shown to be related to other systemic diseases. However in order to assess this relationship, large epidemiological studies are required. Such studies need validated self-report measures. The aim of this systematic review was to assess the validity of self-reported measures in the diagnosis of periodontal disease. The review followed PRISMA guidelines. Medline, Embase and Google Scholar were searched up to January 2016. Two periodontal journals were searched manually. Two reviewers independently made study selection and data extraction...
August 13, 2016: Journal of Periodontology
Farid Dabaghian, Sedigheh Khademian, Amir Azadi, Mohammad Zarshenas
BACKGROUND: As the most common form of dementia, Alzheimer disease is characterized by progressive loss of memory and deterioration of cognitive functions. It is predicted that about 75.63 million people would suffer from dementia by 2030. Apart from conventional remedies, the application of herbal medicines is on the rise. There are numerous natural medicaments reported in the traditional manuscript of Persian medicine. Accordingly, in the present study, the intended remedy was selected and an appropriate pharmacognostical and pharmaceutical evaluations were performed...
May 2016: Iranian Journal of Medical Sciences
Massih Sedigh-Rahimabadi, Mesbah Shams, Mohammadmehdi Fani, Mahsa Rostami Chijan
BACKGROUND: Gingivitis is among the top general health problems in the world, especially in developing countries. Meanwhile, it may be associated with pulmonary and cardiovascular diseases. In a qualitative study, we tried to identify the corresponding terminology to gingivitis in traditional Persian medicine (TPM) and to explain its potential mechanisms, treatments, and prevention characteristics. METHODS: In a literature review, 4 modern textbooks and 18 related articles, 2 traditional medical dictionaries and 12 traditional medical and 4 traditional pharmaceutical texts were assessed by a specific method...
May 2016: Iranian Journal of Medical Sciences
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