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https://www.readbyqxmd.com/read/27913659/formative-research-using-a-community-based-participatory-research-approach-to-develop-an-oral-health-intervention-for-migrant-mexican-families
#1
Tracy L Finlayson, Padideh Asgari, Lisa Hoffman, Ana Palomo-Zerfas, Martha Gonzalez, Nannette Stamm, Maria-Isabel Rocha, Arcela Nunez-Alvarez
Oral health is a leading unmet health need among migrant families. This article describes the 1-year, community-based participatory research (CBPR) approach employed to plan and develop a Líder Communitario (lay community health worker)-led educational intervention for Mexican migrant adult caregivers and their families in three underserved, remote communities in North San Diego County, California. Four partner organizations collaborated, reviewed existing oral health curricula, and sought extensive input on educational topics and research design from key informants, migrant caregivers, and Líderes Communitarios...
December 1, 2016: Health Promotion Practice
https://www.readbyqxmd.com/read/27895769/unusual-lower-back-pain-with-monocytosis-a-case-report
#2
Sheng-Cheng Wu, Tzu-Chuan Huang, Wen-Ya Yu, Yi-Ying Wu
There are numerous causes of lower back pain. In the oncological setting, spine metastasis from a solid tumor is the most common. However, hematological disorders should also be taken into consideration. The current study presents a case of chronic myelomonocytic leukemia with the initial presentation of chronic lower back pain, followed by symptoms that included urinary retention, stool incontinence and left gum swelling, in a patient who was eventually diagnosed with granulocytic sarcoma (GS) over the sacral region...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27883039/structural-and-functional-probing-of-porz-an-essential-bacterial-surface-component-of-the-type-ix-secretion-system-of-human-oral-microbiomic-porphyromonas-gingivalis
#3
Anna M Lasica, Theodoros Goulas, Danuta Mizgalska, Xiaoyan Zhou, Iñaki de Diego, Mirosław Ksiazek, Mariusz Madej, Yonghua Guo, Tibisay Guevara, Magdalena Nowak, Barbara Potempa, Apoorv Goel, Maryta Sztukowska, Apurva T Prabhakar, Monika Bzowska, Magdalena Widziolek, Ida B Thøgersen, Jan J Enghild, Mary Simonian, Arkadiusz W Kulczyk, Ky-Anh Nguyen, Jan Potempa, F Xavier Gomis-Rüth
Porphyromonas gingivalis is a member of the human oral microbiome abundant in dysbiosis and implicated in the pathogenesis of periodontal (gum) disease. It employs a newly described type-IX secretion system (T9SS) for secretion of virulence factors. Cargo proteins destined for secretion through T9SS carry a recognition signal in the conserved C-terminal domain (CTD), which is removed by sortase PorU during translocation. Here, we identified a novel component of T9SS, PorZ, which is essential for surface exposure of PorU and posttranslational modification of T9SS cargo proteins...
November 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27875416/comparison-of-structural-disease-burden-to-health-related-quality-of-life-scores-in-264-adult-spinal-deformity-patients-with-2-year-follow-up-novel-insights-into-drivers-of-disability
#4
Joshua Bakhsheshian, Justin K Scheer, Jeffrey L Gum, Lance Horner, Richard Hostin, Virginie Lafage, Shay Bess, Themistocles S Protopsaltis, Douglas C Burton, Malla Keefe, Robert A Hart, Gregory M Mundis, Christopher I Shaffrey, Frank Schwab, Justin S Smith, Christopher P Ames
STUDY DESIGN: This is a review of a prospective multicenter database. OBJECTIVE: To investigate the relationship between preoperative disability and sagittal deformity in patients with high Oswestry Disability Index (ODI) and no sagittal malalignment, or low ODI and high sagittal malalignment. SUMMARY OF BACKGROUND DATA: The relationship between ODI and sagittal malalignment varies between each adult spinal deformity (ASD) patient. METHODS: A prospective multicenter database of 365 patients with ASD undergoing surgical reconstruction was analyzed...
November 21, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27870992/nanoencapsulation-of-coenzyme-q10-and-vitamin-e-acetate-protects-against-uvb-radiation-induced-skin-injury-in-mice
#5
Natháli S Pegoraro, Allanna V Barbieri, Camila Camponogara, Juliane Mattiazzi, Evelyne S Brum, Marila C L Marchiori, Sara M Oliveira, Letícia Cruz
This study aimed to investigate the feasibility of producing semisolid formulations based on nanocapsule suspensions containing the association of the coenzyme Q10 and vitamin E acetate by adding gellan gum (2%) to the suspensions. Furthermore, we studied their application as an alternative for the treatment of inflammation induced by ultraviolet B (UVB) radiation. For this, an animal model of injury induced by UVB-radiation was employed. All semisolids presented pH close to 5.5, drug content above 95% and mean diameter on the nanometric range, after redispersion in water...
November 9, 2016: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/27868067/purification-and-characterization-of-a-thermostable-%C3%AE-mannanase-from-bacillus-subtilis-be-91-potential-application-in-inflammatory-diseases
#6
Lifeng Cheng, Shengwen Duan, Xiangyuan Feng, Ke Zheng, Qi Yang, Zhengchu Liu
β-mannanase has shown compelling biological functions because of its regulatory roles in metabolism, inflammation, and oxidation. This study separated and purified the β-mannanase from Bacillus subtilis BE-91, which is a powerful hemicellulose-degrading bacterium using a "two-step" method comprising ultrafiltration and gel chromatography. The purified β-mannanase (about 28.2 kDa) showed high specific activity (79, 859.2 IU/mg). The optimum temperature and pH were 65°C and 6.0, respectively. Moreover, the enzyme was highly stable at temperatures up to 70°C and pH 4...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27864174/multilocus-sequence-analysis-of-phylogroup-1-and-2-oral-treponeme-strains
#7
Yong-Biao Huo, Yuki Chan, Donnabella C Lacap-Bugler, Sisu Mo, Patrick C Y Woo, W Keung Leung, Rory M Watt
: More than 75 'species-level' phylotypes of spirochete bacteria belonging to the genus Treponema reside within the human oral cavity. The majority of these oral treponeme phylotypes correspond to as-yet uncultivated taxa, or strains of uncertain standing in taxonomy. Here, we analyze phylogenetic and taxonomic relationships between oral treponeme strains using a multilocus sequence analysis (MLSA) scheme based on the highly-conserved 16S rRNA, pyrH, recA and flaA genes. We utilize this MLSA scheme to analyze genetic data from a curated collection of oral treponeme strains (n=71) of diverse geographical origins...
November 18, 2016: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/27863601/clinical-efficacy-of-turmeric-use-in-gingivitis-a-comprehensive-review
#8
REVIEW
Karissa A Stoyell, Jennifer L Mappus, Mona A Gandhi
INTRODUCTION: Gingivitis affects an estimated 80% of the population, and is characterized as the world's most predominant inflammatory periodontal disease. Without intervention, gingivitis can advance to alveolar bone loss. Therefore, the primary goal in patients suffering with gingivitis is to control plaque buildup and soft tissue inflammation. Current guidelines consider chlorhexidine as the gold standard in the prevention and treatment of gingivitis. However, negative side effects of chlorhexidine, including oral mucosal erosion, discoloration of teeth, and bitter taste, provide an opportunity for alternative medications...
November 2016: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/27847225/mesoporous-silica-nanoparticle-based-enzyme-responsive-system-for-colon-specific-drug-delivery-through-guar-gum-capping
#9
Balmiki Kumar, Senthilguru Kulanthaivel, Animesh Mondal, Smruti Mishra, Biplab Banerjee, Asim Bhaumik, Indranil Banerjee, Supratim Giri
In the global context of increasing colonic diseases, colon specific oral drug delivery systems have shown promise as an effective therapeutic modality. Herein, we developed a mesoporous silica nanoparticle (MSN) based enzyme responsive materials for colon specific drug delivery. We have utilized guar gum, a natural carbohydrate polymer as a capping layer to contain a model drug, such as 5-flurouracil (5FU) within the mesoporous channels of MSN. Analytical characterization including electron microscopy, PXRD, nitrogen sorption, thermogravimetric analysis and FTIR, confirmed that the synthesized MSN with size less than 100nm is of MCM-41type...
October 29, 2016: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/27812917/mouth-the-mirror-of-lungs-where-does-the-connection-lie
#10
REVIEW
Jananni Muthu, Sivaramakrishnan Muthanandam, Jaideep Mahendra
Periodontitis is the chronic destructive disease of the periodontium (Gums) caused by host bacterial interactions. The effect of such host bacterial interactions in oral cavity also evokes a systemic response. Numerous studies have found common mechanisms of destruction for periodontal diseases and other chronic diseases like diabetes mellitus, atherosclerosis, respiratory diseases, and adverse pregnancy outcomes. Oral colonization by respiratory pathogens appears to be a risk factor for development of respiratory diseases and oral interventions aimed at reducing oral bacterial count have resulted in reduced incidence of these reparatory illness...
November 3, 2016: Frontiers of Medicine
https://www.readbyqxmd.com/read/27794507/-a-novel-survey-of-the-ethno-medicinal-knowledge-of-dental-problems-in-manoor-valley-northern-himalaya-pakistan
#11
Inayat Ur Rahman, Farhana Ijaz, Zafar Iqbal, Aftab Afzal, Niaz Ali, Muhammad Afzal, Muhammad Azhar Khan, Said Muhammad, Ghulam Qadir, Muhammad Asif
ETHNOPHARMACOLOGICAL RELEVANCE: In the study area, the traditional knowledge and cultural practices of utilizing medicinal plants in the human healthcare is primarily restricted to the old age members of the community, while younger generation is mostly unaware of the natural wealth usage. AIM OF THE STUDY: We provide the first ever ethno medicinal insights into the management of dental disorders in Pakistan. The prime objective of the study was to explore novel knowledge of these local and remote community members and share it with rest of the world in documented form...
October 26, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27794150/periodontal-and-microbiological-profile-of-intensive-care-unit-inpatients
#12
Alessandra N Porto, Alvaro H Borges, Grace Rocatto, Fernanda Z Matos, Alexandre M Borba, F L Miranda Pedro, Suellen L Lima, Mateus R Tonetto, Matheus C Bandéca, A M Fabio Aranha
INTRODUCTION: The bidirectional relationship between the periodontal diseases and systemic diseases was attributed to the focal infection concept. The aims of this study were to assess the periodontal and microbiological profile of intensive care unit (ICU) inpatients submitted to orotracheal intubation, and classify them regarding gender, age group, ethnic, hospitalization reason and period, nosocomial infection occurrence, and death. MATERIALS AND METHODS: Inpatients were assessed, distributed into toothed and toothless groups...
October 1, 2016: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/27782055/quantitative-determination-of-3-o-acetyl-11-keto-%C3%AE-boswellic-acid-akba-and-other-boswellic-acids-in-boswellia-sacra-flueck-syn-b-carteri-birdw-and-boswellia-serrata-roxb
#13
Giuseppe Mannino, Andrea Occhipinti, Massimo E Maffei
Boswellia serrata and Boswellia sacra (syn. B. carteri) are important medicinal plants widely used for their content of bioactive lipophilic triterpenes. The qualitative and quantitative determination of boswellic acids (BAs) is important for their use in dietary supplements aimed to provide a support for osteoarthritic and inflammatory diseases. We used High Performance Liquid Chromatography (HPLC)-Diode Array Detector (DAD) coupled to ElectroSpray Ionization and tandem Mass Spectrometry (ESI-MS/MS) for the qualitative and quantitative determination of BAs extracted from the gum resins of B...
October 6, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27771932/guggulsterone-and-its-role-in-chronic-diseases
#14
Takanori Yamada, Ken Sugimoto
Guggulsterone is a plant sterol derived from gum resin of Commiphora wightii. The gum resin from guggul plants has been used for thousand years in Ayurveda to treat various disorders, including internal tumors, obesity, liver disorders, malignant sores and ulcers, urinary complaints, intestinal worms, leucoderma, sinuses, edema, and sudden paralytic seizures. Guggulsterone has been identified a bioactive components of this gum resin. This plant steroid has been reported to work as an antagonist of certain nuclear receptors, especially farnesoid X receptor, which regulates bile acids and cholesterol metabolism...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27764966/the-impact-of-comorbidity-on-the-relationship-between-life-stress-and-health-related-quality-of-life-for-chinese-and-korean-american-breast-cancer-survivors
#15
Jung-Won Lim
OBJECTIVE: The current study aimed to (1) identify the occurrence of comorbidities among Chinese- and Korean-American breast cancer survivors (BCS), (2) examine whether health-related quality of life (HRQOL) scores varied with the occurrence of specific comorbidities, and (3) investigate the mediating effect of comorbidities on the relationship between life stress and HRQOL. DESIGN: Data were drawn from the parent study, a cross-sectional study investigating HRQOL in 86 Chinese- and 71 Korean-American BCS in Southern California...
October 21, 2016: Ethnicity & Health
https://www.readbyqxmd.com/read/27749315/von-willebrand-disease-in-sub-saharan-africa-a-first-severe-case-reported-in-cameroon
#16
Claude T Tagny, Pauline N Balôgôg, Francoise Boehlen, Dora Mbanya
In Cameroon, the Yaoundé Hemophilia Treatment Center (HTC) has so far recorded 121 cases of hemophilia and only 10 cases of von Willebrand disease (VWD). We report the case of a 16-year-old girl, living in the north of Cameroon. She presented with severe meno-metrorrhagia, which had increased drastically within the past 3 months, associated more recently by gum bleeding and epistaxis. The coagulation screen showed a prolonged bleeding time. The clinical profile of this young girl and the findings of less than 5% for von Willebrand factor (VWF):Ag and 10% for VWF Ristocetin cofactor suggests a type 3 VWD...
October 2016: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/27737367/validity-of-periodontitis-screening-questions-in-a-brazilian-adult-population-based-study
#17
Renato Quirino Ramos, João Luiz Bastos, Marco Aurélio Peres
Population-based studies assessing self-reported periodontal questions in low-income countries are lacking, and therefore we aimed to assess the accuracy of self-reported periodontal items in Brazil. One thousand one hundred and forty adults from Florianópolis, Brazil, had their periodontium clinically examined, and responded to the following self-reported items on periodontal conditions: Question (Q)1, Do you have any wobbly teeth?; Q2, Do your gums usually bleed?; and Q3, Has your dentist ever told you that you have gum disease? Periodontitis was defined as: a...
October 10, 2016: Brazilian Oral Research
https://www.readbyqxmd.com/read/27645318/efficacy-of-a-fixed-combination-of-0-09%C3%A2-xanthan-gum-0-1%C3%A2-chondroitin-sulfate-preservative-free-vs-polyethylene-glycol-propylene-glycol-in-subjects-with-dry-eye-disease-a-multicenter-randomized-controlled-trial
#18
Ana L Pérez-Balbuena, Juan C Ochoa-Tabares, Sandra Belalcazar-Rey, Cristian Urzúa-Salinas, Laura R Saucedo-Rodríguez, Regina Velasco-Ramos, Raúl G Suárez-Sánchez, Adolfo D Rodríguez-Carrizalez, Aldo A Oregón-Miranda
BACKGROUND: Dry eye disease (DED) is multifactorial, affecting 5-34 % of the global adult population and reducing quality of life. The artificial tears or lubricants are the therapy most used for the treatment of DED, due to their low side effect profile, which attempt to modify the properties of the tear film. The aim of the present study was to evaluate the clinical efficacy of a fixed combination of xanthan gum and chondroitin sulfate preservative free on the ocular surface of patients with dry eye disease during 60 days of intervention...
September 20, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27627917/magnolia-officinalis-l-fortified-gum-improves-resistance-of-oral-epithelial-cells-against-inflammation
#19
Jessica Walker, Julia Maria Imboeck, Joel Michael Walker, Amarnath Maitra, Hady Haririan, Xiaohui Rausch-Fan, Michael Dodds, Taichi Inui, Veronika Somoza
Inflammatory diseases of the periodontal tissues are known health problems worldwide. Therefore, anti-inflammatory active compounds are used in oral care products to reduce long-term inflammation. In addition to inducing inflammation, pathogen attack leads to an increased production of reactive oxygen species (ROS), which may lead to oxidative damage of macromolecules. Magnolia officinalis L. bark extract (MBE) has been shown to possess antioxidant and anti-inflammatory potential in vitro. In the present study, the influence of MBE-fortified chewing gum on the resistance against lipopolysaccharide (LPS)-induced inflammation and oxidative stress of oral epithelial cells was investigated in a four-armed parallel designed human intervention trial with 40 healthy volunteers...
2016: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/27623728/oral-health-knowledge-awareness-and-associated-practices-of-pre-school-children-s-mothers-in-greater-noida-india
#20
Priyanka Sehrawat, K K Shivlingesh, Bhuvandeep Gupta, Richa Anand, Abhinav Sharma, Monica Chaudhry
AIM: To assess the oral health knowledge, awareness and associated exercised practices of pre-school children's mothers in Greater Noida, India. SUBJECTS AND METHODS: The sampling frame for this study was chosen via convenient sampling. It comprised 598 mothers of children aged between 2 and 5 years, attending the paediatrics division of a government and four private hospitals in Greater Noida. A pre-tested questionnaire was distributed to the participants which comprised questions on the participant's sociodemographic characteristics and 23 statements regarding their knowledge, attitude and practices towards their child's oral health...
July 2016: Nigerian Postgraduate Medical Journal
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