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clinical Neuropsychology

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https://www.readbyqxmd.com/read/29042889/screening-ability-of-subjective-memory-complaints-informant-reports-for-cognitive-decline-and-their-combination-in-memory-clinic-setting
#1
Seon Jin Yim, Dahyun Yi, Min Soo Byun, Young Min Choe, Hyo Jung Choi, Hyewon Baek, Bo Kyung Sohn, Jee Wook Kim, Eui-Jung Kim, Dong Young Lee
OBJECTIVE: This study aimed to compare the accuracy of subjective memory complaints, informant-reports for cognitive declines, and their combination for screening cognitive disorders in memory clinic setting. METHODS: One-hundred thirtytwo cognitively normal (CN), 136 mild cognitive impairment (MCI), and 546 dementia who visited the memory clinic in the Seoul National University Hospital underwent standardized clinical evaluation and comprehensive neuropsychological assessment...
September 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29042856/the-utility-of-a-computerized-algorithm-based-on-a-multi-domain-profile-of-measures-for-the-diagnosis-of-attention-deficit-hyperactivity-disorder
#2
Alessandro Crippa, Christian Salvatore, Erika Molteni, Maddalena Mauri, Antonio Salandi, Sara Trabattoni, Carlo Agostoni, Massimo Molteni, Maria Nobile, Isabella Castiglioni
The current gold standard for diagnosis of attention deficit/hyperactivity disorder (ADHD) includes subjective measures, such as clinical interview, observation, and rating scales. The significant heterogeneity of ADHD symptoms represents a challenge for this assessment and could prevent an accurate diagnosis. The aim of this work was to investigate the ability of a multi-domain profile of measures, including blood fatty acid (FA) profiles, neuropsychological measures, and functional measures from near-infrared spectroscopy (fNIRS), to correctly recognize school-aged children with ADHD...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29042492/validation-of-the-telephone-interview-of-cognitive-status-and-telephone-montreal-cognitive-assessment-against-detailed-cognitive-testing-and-clinical-diagnosis-of-mild-cognitive-impairment-after-stroke
#3
Vera Zietemann, Anna Kopczak, Claudia Müller, Frank Arne Wollenweber, Martin Dichgans
BACKGROUND AND PURPOSE: Assessment of cognitive status poststroke is recommended by guidelines but follow-up can often not be done in person. The Telephone Interview of Cognitive Status (TICS) and the Telephone Montreal Cognitive Assessment (T-MoCA) are considered useful screening instruments. Yet, evidence to define optimal cut-offs for mild cognitive impairment (MCI) after stroke is limited. METHODS: We studied 105 patients enrolled in the prospective DEDEMAS study (Determinants of Dementia After Stroke; NCT01334749)...
October 17, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29041995/reproducibility-of-cognitive-profiles-in-psychosis-using-cluster-analysis
#4
Kathryn E Lewandowski, Justin T Baker, Julie M McCarthy, Lesley A Norris, Dost Öngür
OBJECTIVES: Cognitive dysfunction is a core symptom dimension that cuts across the psychoses. Recent findings support classification of patients along the cognitive dimension using cluster analysis; however, data-derived groupings may be highly determined by sampling characteristics and the measures used to derive the clusters, and so their interpretability must be established. We examined cognitive clusters in a cross-diagnostic sample of patients with psychosis and associations with clinical and functional outcomes...
October 18, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29040946/neuropsychological-predictors-of-response-to-cognitive-behavioral-therapy-for-posttraumatic-stress-disorder-in-persons-with-severe-mental-illness
#5
Kim T Mueser, Susan R McGurk, Haiyi Xie, Elisa E Bolton, M Kay Jankowski, Weili Lu, Stanley D Rosenberg, Rosemarie Wolfe
This study examined whether cognitive functioning was related to treatment outcomes in persons with severe mental illness who received a cognitive behavioral therapy (CBT) program for co-occurring posttraumatic stress disorder (PTSD). The study sample was drawn from a larger controlled trial of 108 persons with severe mental illness and PTSD comparing the effects of CBT with treatment as usual on PTSD and related outcomes, with assessments conducted at baseline, post-treatment, and 3- and 6-month follow-ups...
October 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29039851/quantifying-person-level-brain-network-functioning-to-facilitate-clinical-translation
#6
T M Ball, A N Goldstein-Piekarski, J M Gatt, L M Williams
Although advances in neuroimaging have yielded insights into the intrinsic organization of human brain networks and their relevance to psychiatric and neurological disorders, there has been no translation of these insights into clinical practice. One necessary step toward clinical translation is identifying a summary metric of network function that is reproducible, reliable, and has known normative data, analogous to normed neuropsychological tests. Our aim was therefore to establish the proof of principle for such a metric, focusing on the default mode network (DMN)...
October 17, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/29039829/-factors-for-the-development-of-persistent-postoperative-cognitive-dysfunction-in-patients-undergoing-coronary-artery-bypass-surgery-under-extracorporeal-circulation
#7
O A Trubnikova, I V Tarasova, O V Maleva, E S Kagan, O L Barbarash, L S Barbarash
AIM: To analyze the factors contributing to the increased risk of persistent postoperative cognitive dysfunction (POCD) in patients undergoing coronary artery bypass surgery (CABS) under extracorporeal circulation (EC). SUBJECTS AND METHODS: 257 male patients aged 45 to 69 years with coronary heart disease (CHD) undergoing elective CABS under EC were examined. In addition to conventional clinical examination, all the patients underwent neuropsychological testing 3-5 days before, 7-14 days and 1 year after CABS...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/29037499/neuropsychiatric-and-cognitive-profile-of-early-richardson-s-syndrome-progressive-supranuclear-palsy-parkinsonism-and-parkinson-s-disease
#8
Clelia Pellicano, Francesca Assogna, Nystya Cellupica, Federica Piras, Mariangela Pierantozzi, Alessandro Stefani, Rocco Cerroni, Bruno Mercuri, Carlo Caltagirone, Francesco E Pontieri, Gianfranco Spalletta
INTRODUCTION: The two main variants of Progressive Supranuclear Palsy (PSP), Richardson's syndrome (PSP-RS) and PSP-parkinsonism (PSP-P), share motor and non-motor features with Parkinson's disease (PD) particularly in the early stages. This makes the precocious diagnosis more challenging. We aimed at defining qualitative and quantitative differences of neuropsychiatric and neuropsychological profiles between PSP-P, PSP-RS and PD patients recruited within 24 months after the onset of symptoms, in order to clarify if the identification of peculiar cognitive and psychiatric symptoms is of help for early PSP diagnosis...
October 6, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29037340/-neuropsychiatry-of-movement-disorders
#9
Juan Manuel Orjuela-Rojas, Gustavo Adolfo Barrios Vincos, Melisa Alejandra Martínez Gallego
Movement disorders can be defined as neurological syndromes presenting with excessive or diminished automatic or voluntary movements not related to weakness or spasticity. Both Parkinson's disease (PD) and Huntington's disease (HD) are well-known examples of these syndromes. The high prevalence of comorbid psychiatric symptoms like depression, anxiety, obsessive-compulsive symptoms, hallucinations, delusions, impulsivity, sleep disorders, apathy and cognitive impairment mean that these conditions must be regarded as neuropsychiatric diseases...
October 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29037162/feasibility-of-a-multi-modal-exercise-program-on-cognition-in-older-adults-with-type-2-diabetes-a-pilot-randomised-controlled-trial
#10
M L Callisaya, R M Daly, J E Sharman, D Bruce, T M E Davis, T Greenaway, M Nolan, R Beare, M G Schultz, T Phan, L C Blizzard, V K Srikanth
BACKGROUND: Type 2 Diabetes (T2D) is associated with increased risk of dementia. We aimed to determine the feasibility of a randomised controlled trial (RCT) examining the efficacy of exercise on cognition and brain structure in people with T2D. METHODS: A 6-month pilot parallel RCT of a progressive aerobic- and resistance-training program versus a gentle movement control group in people with T2D aged 50-75 years (n = 50) at the University of Tasmania, Australia...
October 16, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29036183/mri-assessed-atrophy-subtypes-in-alzheimer-s-disease-and-the-cognitive-reserve-hypothesis
#11
Karin Persson, Rannveig Sakshaug Eldholm, Maria Lage Barca, Lena Cavallin, Daniel Ferreira, Anne-Brita Knapskog, Geir Selbæk, Anne Brækhus, Ingvild Saltvedt, Eric Westman, Knut Engedal
BACKGROUND/AIMS: MRI assessment of the brain has demonstrated four different patterns of atrophy in patients with Alzheimer's disease dementia (AD): typical AD, limbic-predominant AD, hippocampal-sparing AD, and a subtype with minimal atrophy, previously referred to as no-atrophy AD. The aim of the present study was to identify and describe the differences between these four AD subtypes in a longitudinal memory-clinic study. METHODS: The medial temporal lobes, the frontal regions, and the posterior regions were assessed with MRI visual rating scales to categorize 123 patients with mild AD according to ICD-10 and NINCDS-ADRDA criteria and the clinical dementia rating scale (CDR) into atrophy subtypes...
2017: PloS One
https://www.readbyqxmd.com/read/29035999/effects-on-18f-fdg-pet-ct-brain-glucose-metabolism-in-rectal-cancer-patients-undergoing-neoadjuvant-chemotherapy
#12
Alexei M C Machado, Theara C Fagundes, Arnoldo Mafra, Rodrigo G Silva, Ana Carolina G Castro, Marcelo Mamede
PURPOSE: Retrospective study of the effects of anticancer treatment on the brain metabolism of patients diagnosed with rectal cancer based on a large and homogeneous sample of 40 paired F-FDG PET/CT volumes taken from 20 patients. The results are compared to the ones presented by related works to help elucidating the mechanisms of neurotoxicity associated to a decrease in memory, learning and motor skills. PATIENTS AND METHODS: Twenty patients with rectal adenocarcinoma were scanned before and after neoadjuvant chemoradiation based exclusively on 5-fluorouracil and leucovorin...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035981/clinical-utility-of-oculomotor-and-electrophysiological-measures-in-identifying-concussion-history
#13
Patrick S Ledwidge, Jessie N Patterson, Dennis L Molfese, Julie A Honaker
OBJECTIVE: To examine whether oculomotor and electrophysiological measures improve the clinical performance of the typical concussion protocol for classifying collegiate athletes with a history of concussion. DESIGN: Cross-sectional. SETTING: University Athletic Medicine and Research Facility. PARTICIPANTS: Forty-five varsity collegiate athletes. INDEPENDENT VARIABLES: Collegiate varsity athletes with or without a history of a diagnosed concussion...
October 10, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29035070/verbal-fluency-in-male-and-female-schizophrenia-patients-different-patterns-of-association-with-processing-speed-working-memory-span-and-clinical-symptoms
#14
Gildas Brébion, Christian Stephan-Otto, Susana Ochoa, Lourdes Nieto, Montserrat Contel, Judith Usall
OBJECTIVE: Decreased processing speed in schizophrenia patients has been identified as a major impairment factor in various neuropsychological domains. Working memory span has been found to be involved in several deep or effortful cognitive processes. We investigated the impact that these 2 cognitive functions may have on phonological and semantic fluency in schizophrenia patients and healthy participants. METHOD: Fifty-five patients with schizophrenia and 60 healthy participants were administered a neuropsychological battery including phonological and semantic fluency, working memory, and cognitive and motor speed...
October 16, 2017: Neuropsychology
https://www.readbyqxmd.com/read/29034496/clinical-impact-of-the-microembolic-signal-burden-during-catheter-ablation-for-atrial-fibrillation-just-a-lot-of-noise
#15
Christian von Bary, Thomas Deneke, Thomas Arentz, Anja Schade, Heiko Lehrmann, Susanne Schwab-Malek, Sabine Fredersdorf, Dobri Baldaranov, Lars Maier, Felix Schlachetzki
OBJECTIVES: Microembolic signal detection by transcranial Doppler ultrasonography may be considered a surrogate for cerebral events during invasive cardiac procedures. However, the impact of the microembolic signal count during pulmonary vein isolation on the clinical outcome is not well evaluated. We investigated the effect of the microembolic signal count on the occurrence of new silent cerebral embolism measured by diffusion-weighted imaging (DWI)-magnetic resonance imaging (MRI), changes in neuropsychological testing, and the occurrence of clinical events during long-term follow-up after pulmonary vein isolation...
October 16, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29033861/neuropsychological-impairment-in-detoxified-alcohol-dependent-subjects-with-preserved-psychosocial-functioning
#16
Catherine Martelli, Amélie Petillion, Marine Brunet-Lecomte, Rubén Miranda Marcos, Sandra Chanraud, Ammar Amirouche, Alexia Letierce, Nikoleta Kostogianni, Hervé Lemaitre, Henri-Jean Aubin, Lisa Blecha, Michel Reynaud, Jean-Luc Martinot, Amine Benyamina
BACKGROUND: Chronic alcoholism and its related cognitive impairments are associated with increased social, relational, and professional deficits which have a variable overall impact on social integration. These impairments are known to have varying severities and have rarely been studied among healthy alcohol-dependent subjects with preserved psychosocial functioning. Thus, the objective of this study is to describe neuropsychological performance in this particular population. METHOD: Twenty-nine socially adjusted alcohol-dependent men, hospitalized for a first or second withdrawal and abstinent for 3 weeks minimum, were compared to 29 healthy non-alcoholic controls...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29033570/atypical-depression-current-perspectives
#17
REVIEW
Dorota Łojko, Janusz K Rybakowski
The history and present status of the definition, prevalence, neurobiology, and treatment of atypical depression (AD) is presented. The concept of AD has evolved through the years, and currently, in Diagnostic and Statistical Manual of Mental Disorders (DSM), Fifth Edition, the specifier of depressive episode with atypical feature is present for both diagnostic groups, that is, depressive disorders and bipolar and related disorders. This specifier includes mood reactivity, hyperphagia, hypersomnia, leaden paralysis, and interpersonal rejection sensitivity...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29032776/neuropsychological-recovery-trajectories-in-moderate-to-severe-traumatic-brain-injury-influence-of-patient-characteristics-and-diffuse-axonal-injury
#18
Amanda R Rabinowitz, Tessa Hart, John Whyte, Junghoon Kim
OBJECTIVES: The goal of the present study was to elucidate the influence of demographic and neuropathological moderators on the longitudinal trajectory neuropsychological functions during the first year after moderate to severe traumatic brain injury (TBI). In addition to examining demographic moderators such as age and education, we included a measure of whole-brain diffuse axonal injury (DAI), and examined measures of processing speed (PS), executive function (EF), and verbal learning (VL) separately...
October 16, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29032750/longitudinal-neuropsychological-outcome-in-taiwanese-alzheimer-s-disease-patients-treated-with-medication
#19
Pi-Shan Sung, Meng-Ni Wu, Ping-Song Chou, Hui-Chen Su, Sheng-Hsiang Lin, Yuan-Han Yang
Background The longitudinal change of neuropsychological tests (NPTs) in treated Alzheimer's disease (AD) is essential to understand the interplay of a therapeutic response from medication and a disease decline due to degenerative processes. The aim of our study is to investigate the annual cognitive progression as measured by commonly used NPTs in treated AD patients and to assess the potential predictors of disease progression. Methods Participants (N=455) diagnosed with AD and treated with cholinesterase inhibitors (ChEIs) or memantine at memory clinics in three hospitals in southern Taiwan from January 2009 to December 2014 were enrolled in this prospectively registered study...
October 10, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/29028904/considerations-for-clinical-neuropsychological-evaluation-in-amyotrophic-lateral-sclerosis
#20
Susan C Woolley, Beth K Rush
The clinical neuropsychologist has the opportunity to be uniquely involved in the evaluation and treatment of individuals with amyotrophic lateral sclerosis (ALS). We review the current literature that defines cognitive and behavioral symptoms in ALS, including current knowledge of the neuropathological and genetic underpinning for these symptoms. There are unique considerations for clinical neuropsychological evaluation and clinical research in ALS and we highlight these in this review. Specifically, we shed light on special factors that contribute to our understanding of cognitive and behavioral impairment in ALS, including co-morbid symptoms, differential diagnosis, and considerations for longitudinal tracking of phenotypes...
September 28, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
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