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iron oxide nanoparticles

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https://www.readbyqxmd.com/read/29454269/biological-effects-of-four-iron-containing-nanoremediation-materials-on-the-green-alga-chlamydomonas-sp
#1
Nhung H A Nguyen, Nadia R Von Moos, Vera I Slaveykova, Katrin Mackenzie, Rainer U Meckenstock, Silke Thűmmler, Julian Bosch, Alena Ševců
As nanoremediation strategies for in-situ groundwater treatment extend beyond nanoiron-based applications to adsorption and oxidation, ecotoxicological evaluations of newly developed materials are required. The biological effects of four new materials with different iron (Fe) speciations ([i] FerMEG12 - pristine flake-like milled Fe(0) nanoparticles (nZVI), [ii] Carbo-Iron ® - Fe(0)-nanoclusters containing activated carbon (AC) composite, [iii] Trap-Ox® Fe-BEA35 (Fe-zeolite) - Fe-doped zeolite, and [iv] Nano-Goethite - 'pure' FeOOH) were studied using the unicellular green alga Chlamydomonas sp...
February 14, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29453540/cellular-and-molecular-toxicity-of-iron-oxide-nanoparticles
#2
Blanca Laffon, Natalia Fernández-Bertólez, Carla Costa, Fátima Brandão, João Paulo Teixeira, Eduardo Pásaro, Vanessa Valdiglesias
Iron oxide nanoparticles (ION) have attracted much attention because of their particular physico-chemical properties, including superparamagnetism. These features make them suitable for many purposes and several interesting biomedical applications, such as to increase contrast in magnetic resonance imaging (MRI), as drug delivery systems and as hyperthermia agents. However, they have also shown to be easily accumulated in diverse tissues and induce toxicity at different levels. This chapter reviews the different cellular and molecular effects induced by ION reported from in vitro studies with human and non-human cell lines...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29452944/iron-engineered-mesoporous-silica-nanocatalyst-with-biodegradable-and-catalytic-framework-for-tumor-specific-therapy
#3
Liying Wang, Minfeng Huo, Yu Chen, Jianlin Shi
Inorganic mesoporous silica-based nanovehicles are highly promising for drug delivery but still suffer from the disadvantages of lacking functionality and poor biodegradability on account of the inert silica framework. Moreover, conventional cancer therapeutics typically employ toxic anticancer drugs or invasive external irradiations, which will inevitably give rise to severe adverse effects and diminished therapeutic outcome. In this work, we report on the iron engineered framework of mesoporous silica nanoparticles (MSNs) to fabricate a nanocatalyst with biodegradable and catalytic framework via a "dissolution-regeneration" strategy (designated as rFeO x -HMSN)...
February 9, 2018: Biomaterials
https://www.readbyqxmd.com/read/29450799/iron-oxide-labeling-does-not-affect-differentiation-potential-of-human-bone-marrow-mesenchymal-stem-cells-exhibited-by-their-differentiation-into-cardiac-and-neuronal-cells
#4
Sujata Mohanty, Krishan Gopal Jain, Sushmita Bose Nandy, Anupama Kakkar, Manoj Kumar, Amit Kumar Dinda, Harpal Singh, Alok Ray
Mesenchymal stem cells (MSCs) have shown promising outcomes in cardiac and neuronal diseases. Efficient and noninvasive tracking of MSCs is essential to harness their therapeutic potential. Iron oxide nanoparticles (IONPs) have emerged as effective means to label stem cells and visualize them using magnetic resonance imaging (MRI). It is known that IONPs do not affect viability and cell proliferation of stem cells. However, very few studies have demonstrated differentiation potential of iron oxide-labeled MSCs and their differentiation into specific lineages that can contribute to cellular therapies...
February 15, 2018: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/29448887/fabrication-of-iron-oxide-nanocolloids-using-metallosurfactant-based-microemulsions-antioxidant-activity-cellular-and-genotoxicity-towards-vitis-vinifera
#5
Gurpreet Kaur, Varsha Dogra, Rajeev Kumar, Sandeep Kumar, Kashmir Singh
The present work aims at the fabrication of iron oxide nanocolloids using biocompatible microemulsion and their cytotoxic, genotoxic effect on Vitis vinifera plant has been evaluated. The three-iron based metallosurfactant complexes were synthesized. Nanosuspensions (Ns) were prepared using microemulsion technique and for the purpose, the microemulsion was prepared using oleic acid, butanol, tween 80 and as synthesized iron metallosurfactant. In this technique, no additional capping agent and/or reducing agent was added...
February 16, 2018: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/29448628/functionalized-magnetic-plga-nanospheres-for-targeting-and-bioimaging-of-breast-cancer
#6
Seung-Jun Lee, Hee-Jin Kim, Yong-Min Huh, Il Won Kim, Jae Hyun Jeong, Jin-Chul Kim, Jong-Duk Kim
Superparamagnetic iron oxide nanoparticles (SPIONs) are actively used as highly sensitive imaging probes to provide contrast in MRI. In this study, we propose the use of SPIONs encapsulated with antibody-conjugated poly(lactic-co-glycolic acid) (PLGA) as a potent theragnostic agent. The SPIONs were synthesized by a chemical co-precipitation method of ferric and ferrous ions, and subsequently encapsulated with PLGA by using an emulsification-diffusion method. Herceptin was chemically conjugated to the SPION-encapsulating PLGA nanoparticles to target the human epidermal growth factor receptor 2 (Her2/neu) overexpressing breast cancers...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448591/synthesis-of-hollow-iron-oxide-nanospheres-and-their-application-to-gas-sensors
#7
Kyung Hee Oh, Hyung Ju Park, Shin Wook Kang, Ji Chan Park, Ki Min Nam
Hollow nanomaterials have attracted great interest because of their many applications in catalysis, nanoreactors, drug delivery systems, for lubrication and in gas sensors. Here, carbon sphere templates were prepared from glucose under hydrothermal conditions to facilitate the synthesis of hollow Fe2O3 nanospheres. Thermal decomposition of an iron precursor in benzylalcohol with the carbon spheres resulted in the deposition of Fe3O4 nanoparticles on the carbon sphere templates. The nanoparticles on the carbon surface naturally agglomerate and form a dense oxide shell during the calcination step, which produces typical Fe2O3 hollow structures...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448510/preparation-and-in-vivo-biodistribution-of-ultra-small-superparamagnetic-iron-oxide-nanoparticles-with-high-magnetic-targeting-response
#8
Xiaoyu Han, Pingping Yao, Chao Cheng, Hongmin Yuan, Yuxiang Yang, Chaoying Ni
The ultra-small superparamagnetic iron oxide (USPIO) particles with high saturation magnetization and good superparamagnetism were prepared by reverse micro-emulsions using novel C16E15 as surfactant, which can reduce magnetic dipole-dipole interaction, hence decreasing the critical blocking temperature (TB). Powder X-ray diffraction (XRD), Infrared spectrum (FT-IR), Transmission electron microscope (TEM), X-ray photoelectron spectroscopy (XPS), and Vibrating sample magnetometer (VSM) were used to characterize the magnetic particles...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29443880/magnetic-nanoparticles-interact-and-pass-an-in-vitro-co-culture-blood-placenta-barrier-model
#9
Elena K Müller, Christine Gräfe, Frank Wiekhorst, Christian Bergemann, Andreas Weidner, Silvio Dutz, Joachim H Clement
Magnetic nanoparticles are interesting tools for biomedicine. Before application, critical prerequisites have to be fulfilled. An important issue is the contact and interaction with biological barriers such as the blood-placenta barrier. In order to study these processes in detail, suitable in vitro models are needed. For that purpose a blood-placenta barrier model based on the trophoblast-like cell line BeWo and primary placenta-derived pericytes was established. This model was characterized by molecular permeability, transepithelial electrical resistance and cell-cell-contact markers...
February 14, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29442958/chemical-preparation-of-bimetallic-fe-ag-core-shell-composite-nanoparticles
#10
Wenjea J Tseng, Yi-Chen Chuang
Bimetallic iron/silver (Fe/Ag) core/shell nanoparticles were prepared by chemical reduction from ferrous sulfate in the presence of sodium borohydride as a reducing agent in water, followed then by redox transmetalation with addition of silver nitrate (AgNO3) solution. When the reduction temperature was increased from room temperature to 85 °C, Fe nanoparticles with a reduced crystallite size ranging from 5.5 to 2.0 nm resulted. The particles changed from spherical to plate-like morphology as the temperature reached 85 °C...
April 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442716/development-of-a-promising-antitumor-compound-based-on-rhodium-ii-succinate-associated-with-iron-oxide-nanoparticles-coated-with-lauric-acid-albumin-hybrid-synthesis-colloidal-stability-and-cytotoxic-effect-in-breast-carcinoma-cells
#11
Matheus Oliveira da Silva, Marcella Lemos Brettas Carneiro, Joseílma Luciana Neves Siqueira, Sônia Nair Báo, Aparecido Ribeiro de Souza
In this study, we report the synthesis and characterization of a new rhodium(II) succinate complex (Rh2(suc)4) and its immobilization on lauric acid bilayer-coated maghemite nanoparticles (MGH-2L/Rh2(suc)4) and subsequent adsorption with bovine serum albumin (MGH-2L/Rh2(suc)4/BSA). Rh2(suc)4 has been characterized by elemental analysis, potentiometric titration, TGA, MS, FTIR and UV-Vis analysis. The maghemite phase was confirmed by XRD, and a diameter of 10 nm was obtained by Sherrer equation. The VSM experiment showed superparamagnetic properties...
June 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442644/carbonization-of-fe-based-metal-organic-frameworks-with-mesoporous-structure-as-electrocatalyst-for-catalysis-of-oxygen-to-hydrogen-peroxide
#12
Rong Liu, Ling Ran, Bei Niu, Yi Wei
H2O2 production from electron reduction of oxygen (O2) is considered to be a potential alternative to the current anthraquinone process. Herein, we reported a mesoporous catalyst with iron-carboxylate metal-organic framework (MOF) as precursors to catalyze O2 to hydrogen peroxide (H2O2). Iron-carboxylate MOF (Fe-MOF) was synthesized by the novel cetyltrimethylammonium bromide (CTAB)-citric acid (CA) double-template method. The SEM and SAXD results revealed octahedral structure of the nanoparticles, as well as the presence of mesopores in the Fe-MOF, while the molar ratio 2...
July 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29438105/magnetic-resonance-and-photoacoustic-imaging-of-brain-tumor-mediated-by-mesenchymal-stem-cell-labeled-with-multifunctional-nanoparticle-introduced-via-carotid-artery-injection
#13
Yang Qiao, Joy Gumin, Christopher MacLellan, Feng Gao, Richard Bouchard, Frederick Lang, R Jason Stafford, Marites P Melancon
To evaluate the feasibility of visualizing bone marrow-derived human mesenchymal stem cells (MSCs) labeled with a gold-coated magnetic resonance (MR)-active multifunctional nanoparticle (SPIO@Au) for assessing the extent of MSC homing in glioma- bearing mice following carotid artery MSC injection. MATERIALS AND METHODS: Nanoparticle containing superparamagnetic iron oxide coated with gold (SPIO@Au) having a diameter of ~82 nm and maximum absorbance in the near infrared (NIR) region was synthesized...
February 13, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29434378/synthesis-and-characterization-of-graphite-encapsulated-iron-nanoparticles-from-ball-milling-assisted-low-pressure-chemical-vapor-deposition
#14
Duygu Ağaoğulları, Steven J Madsen, Burcu Ögüt, Ai Leen Koh, Robert Sinclair
Graphite-encapsulated Fe nanoparticles were synthesized using a combined method of high-energy ball milling and low-pressure chemical vapor deposition (LPCVD). Fe2O3 and graphite powders were milled to increase their surface areas and obtain a more homogeneous distribution. LPCVD was performed at a pressure of ~0.57 Torr in a tube furnace under a CH4/H2 atmosphere at 1050°C for 1 and 3 h. As-synthesized samples were purified in a 2 M HF solution. Characterization was performed using X-ray diffractometry (XRD), scanning and transmission electron microscopy (SEM and TEM) and alternating gradient magnetometry (AGM)...
November 2017: Carbon
https://www.readbyqxmd.com/read/29434110/detection-and-quantification-of-4-methylimidazole-in-cola-by-matrix-assisted-laser-desorption-ionization-mass-spectrometry-with-fe2o3-nanoparticles-on-zeolite
#15
Yosuke Fujii, Yuqi Ding, Taichi Umezawa, Takafumi Akimoto, Jiawei Xu, Takashi Uchida, Tatsuya Fujino
Food additives generally used in carbonated drinks, such as 4-methylimidazole (4MI), caffeine (Caf?), citric acid (CA), and aspartame (Apm), were measured by matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) using nanometer-sized particles of iron oxide (Fe2O3 NPs). The quantification of 4MI in Coca Cola (C-cola) was carried out. In order to improve the reproducibility of the peak intensities, Fe2O3 NPs loaded on ZSM5 zeolite were used as the matrix for quantification. By using 2-ethylimidazole (2EI) as the internal standard, the amount of 4MI in C-cola was determined to range from 88 to 65 μg/355 mL...
2018: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/29433060/dual-tumor-targeted-multifunctional-magnetic-hyaluronic-acid-micelles-for-enhanced-mr-imaging-and-combined-photothermal-chemotherapy
#16
Shaohui Zheng, Jiwon Han, Zhen Jin, Chang-Sei Kim, Sukho Park, Kyu-Pyo Kim, Jong-Oh Park, Eunpyo Choi
Multifunctional polymeric micelles were developed as a promising dual tumor-targeted drug delivery platform for magnetic resonance (MR) imaging and combined photothermal-chemotherapy. HA-C16 copolymers were synthesized via peptide formation process with subsequent co-encapsulation of therapeutic agent docetaxel (DTX) and superparamagnetic iron oxide nanoparticles (SPIONs) to form the multifunctional micelles. The micelles exhibited uniform nanosize and remarkable colloidal stability in aqueous solution. The sustained drug release behavior from HA micelles was observed over the test period...
February 5, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29432151/identification-and-paleoclimatic-significance-of-magnetite-nanoparticles-in-soils
#17
Imad A M Ahmed, Barbara A Maher
In the world-famous sediments of the Chinese Loess Plateau, fossil soils alternate with windblown dust layers to record monsoonal variations over the last ∼3 My. The less-weathered, weakly magnetic dust layers reflect drier, colder glaciations. The fossil soils (paleosols) contain variable concentrations of nanoscale, strongly magnetic iron oxides, formed in situ during the wetter, warmer interglaciations. Mineralogical identification of the magnetic soil oxides is essential for deciphering these key paleoclimatic records...
February 5, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29431053/nanoparticle-mediated-cell-capture-enables-rapid-endothelialization-of-a-novel-bare-metal-stent
#18
Brandon J Tefft, Susheil Uthamaraj, Adriana Harbuzariu, Jonathan Harburn, Tyra A Witt, Brant Newman, Peter J Psaltis, Ota Hlinomaz, David R Holmes, Rajiv Gulati, Robert D Simari, Dan Dragomir-Daescu, Gurpreet S Sandhu
Incomplete endothelialization of intracoronary stents has been associated with stent thrombosis and recurrent symptoms, whereas prolonged use of dual antiplatelet therapy increases bleeding related adverse events. Facilitated endothelialization has the potential to improve clinical outcomes in patients who are unable to tolerate dual antiplatelet therapy. The objective of this study is to demonstrate the feasibility of magnetic cell capture to rapidly endothelialize intracoronary stents in a large animal model...
February 12, 2018: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29429940/review-of-novel-sentinel-lymph-node-biopsy-techniques-in-breast-cancer-patients-treated-with-neoadjuvant-chemotherapy
#19
REVIEW
Yeliz Emine Ersoy, Huseyin Kadioglu
Breast cancer patients who present with nodal metastasis receive neoadjuvant chemotherapy (NAC) with increasing frequency and can have complete pathologic response after treatment. In this clinical scenario, sentinel node mapping and biopsy are gaining acceptance instead of axillary dissection to avoid morbidity. Biopsy proven positive lymph nodes must be reliably excised and examined after NAC to further decrease the false negativity rate of sentinel lymph node (SLN) surgery. The standard method for axillary staging in breast cancer patients even after NAC is SLN biopsy (SLNB) with a radioisotope, blue dye, or both (dual technique)...
January 31, 2018: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29428710/simultaneous-removal-of-amoxicillin-ampicillin-and-penicillin-by-clay-supported-fe-ni-bimetallic-nanoparticles
#20
Xiulan Weng, Wanling Cai, Ruifang Lan, Qian Sun, Zuliang Chen
This study examined functional bentonite-supported nanoscale Fe/Ni (B-Fe/Ni) for the simultaneous removal of β-lactam antibiotics such as amoxicillin (AMX), ampicillin (AMP) and penicillin (PEN). The results show only 94.6% of AMX, 80.6% of AMP and 53.7% of PEN were removed in the mixed antibiotic solution, while 97.5% of AMX, 85.1% of AMP and 74.5% of PEN were removed in individual antibiotic solution. The decreased removal in a mixed antibiotic solution was attributed to competition between antibiotics for: firstly, active sites of iron oxide for the adsorption; and secondly, accepted electrons for the degradation in passivation of the nZVI surface...
February 8, 2018: Environmental Pollution
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