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https://www.readbyqxmd.com/read/29726680/natural-stilbenoids-have-anti-inflammatory-properties-in-vivo-and-down-regulate-the-production-of-inflammatory-mediators-no-il6-and-mcp1-possibly-in-a-pi3k-akt-dependent-manner
#1
Heikki Eräsalo, Mari Hämäläinen, Tiina Leppänen, Ilari Mäki-Opas, Mirka Laavola, Raisa Haavikko, Jari Yli-Kauhaluoma, Eeva Moilanen
Stilbenoids are a group of polyphenolic compounds found in plants, trees, berries, and nuts. Stilbenoids have been shown to serve an antimicrobial and antifungal function in plants. There is also evidence that as a part of the human diet, stilbenoids play an important role as antioxidants and may have anti-inflammatory effects. The PI3K/Akt pathway is a well-characterized signaling pathway controlling cellular functions involved in growth and cell cycle and in metabolism. There is also increasing evidence to show the involvement of this pathway in the regulation of inflammatory responses...
May 4, 2018: Journal of Natural Products
https://www.readbyqxmd.com/read/29700869/tree-nut-allergies-allergen-homology-cross-reactivity-and-implications-for-therapy
#2
Johanna M Smeekens, Kenneth Bagley, Michael Kulis
Tree nut allergy is a potentially life-threatening disease that is increasing in prevalence, now affecting 1% of the general population in the United States. While other food allergies often resolve spontaneously, tree nut allergies are outgrown in less than 10% of cases. Due to the likelihood of cross-sensitization to multiple tree nut allergens, the current treatment guideline is strict avoidance of all nuts once one tree nut allergy has been diagnosed. For example, walnut and pecan are highly cross-reactive, along with cashew and pistachio, but the extent of clinical, IgE-mediated cross-reactivity among other tree nuts remains unclear, therefore making avoidance of all tree nuts a safe approach...
April 27, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29694395/transcriptome-analysis-of-pecan-seeds-at-different-developing-stages-and-identification-of-key-genes-involved-in-lipid-metabolism
#3
Zheng Xu, Jun Ni, Faheem Afzal Shah, Qiaojian Wang, Zhaocheng Wang, Lifang Wu, Songling Fu
Pecan is an economically important nut crop tree due to its unique texture and flavor properties. The pecan seed is rich of unsaturated fatty acid and protein. However, little is known about the molecular mechanisms of the biosynthesis of fatty acids in the developing seeds. In this study, transcriptome sequencing of the developing seeds was performed using Illumina sequencing technology. Pecan seed embryos at different developmental stages were collected and sequenced. The transcriptomes of pecan seeds at two key developing stages (PA, the initial stage and PS, the fast oil accumulation stage) were also compared...
2018: PloS One
https://www.readbyqxmd.com/read/29688446/evaluation-of-nasonov-pheromone-dispensers-for-pollinator-attraction-in-apple-blueberry-and-cherry
#4
J Williamson, C G Adams, R Isaacs, L J Gut
Declines in the number of commercial honey bees (Apis mellifera L.) (Hymenoptera: Apidae) and some wild bee species around the world threaten fruit, nut, and vegetable production and have prompted interest in developing methods for gaining efficiencies in pollination services. One possible approach would be to deploy attractants within the target crop to increase the number of floral visits. In this study, we evaluate two new pollinator attractants, Polynate and SPLAT Bloom, for their ability to increase pollinator visitation and fruit set in apple (Malus pumila Mill...
April 23, 2018: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29680588/tree-nut-allergens
#5
Sabine Geiselhart, Karin Hoffmann-Sommergruber, Merima Bublin
Tree nuts are considered as part of a healthy diet due to their high nutritional quality. However, they are also a potent source of allergenic proteins inducing IgE mediated hypersensitivity often causing serious, life-threatening reactions. The reported prevalence of tree nut allergy is up to 4.9% worldwide. The general term "tree nuts" comprises a number of nuts, seeds, and drupes, derived from trees from different botanical families. For hazelnut and walnut several allergens have been identified which are already partly applied in component resolved diagnosis, while for other tree nuts such as macadamia, coconut, and Brazil nut only individual allergens were identified and data on additional allergenic proteins are missing...
April 18, 2018: Molecular Immunology
https://www.readbyqxmd.com/read/29663520/national-trends-in-emergency-department-visits-and-hospitalizations-for-food-induced-anaphylaxis-in-us-children
#6
S Megan Motosue, M Fernanda Bellolio, K Holly Van Houten, D Nilay Shah, L Ronna Campbell
BACKGROUND: Food is the leading cause of anaphylaxis in children seen in emergency departments in the United States, yet data on emergency department visits and hospitalizations related to food-induced anaphylaxis are limited. The objective of our study was to examine national time trends of pediatric food-induced anaphylaxis-related emergency department visits and hospitalizations. METHODS: We conducted an observational study using a national administrative claims database from 2005 through 2014...
April 17, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29623490/food-allergy
#7
REVIEW
Onyinye I Iweala, Shailesh K Choudhary, Scott P Commins
PURPOSE OF REVIEW: The goal of this review is to present an updated summary of the natural history of major childhood and adult food allergies and report recent advances in potential treatments for food allergy. RECENT FINDINGS: The most common childhood food allergies are typically outgrown by adolescence or adulthood. However, peanut/tree nut allergies appear to more commonly persist into adulthood. Adults can develop new IgE-mediated food allergies; the most common is oral allergy syndrome...
April 5, 2018: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29618933/current-perspectives-on-tree-nut-allergy-a-review
#8
REVIEW
Tamar Weinberger, Scott Sicherer
Tree nut (TN) allergy is common and often severe. It has become an important health concern as availability and consumption have increased. Prevalence varies by age and geographic region and appears to have increased in children. Accidental ingestion of TNs is common. Unfortunately, there is a lower likelihood of resolution of TN allergy, roughly 10%. TN-specific skin tests and serum immunoglobulin E levels can help aid in the diagnosis of TN allergy, but a careful medical history is important because a positive test in isolation is not typically diagnostic...
2018: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/29616249/anti-aging-potential-of-tree-nuts-with-a-focus-on-the-phytochemical-composition-molecular-mechanisms-and-thermal-stability-of-major-bioactive-compounds
#9
REVIEW
Marius Emil Rusu, Ana-Maria Gheldiu, Andrei Mocan, Laurian Vlase, Daniela-Saveta Popa
Tree nuts, complete functional foods, contain macro- and micronutrients of high biological value. These bioactive compounds have a synergistic effect in preventing and delaying many age-related pathologies (e.g. cardiovascular diseases, stroke, type 2 diabetes mellitus, certain types of cancer, and several neurodegenerative diseases). Tree nuts are low in carbohydrates, but they abound in healthy fatty acids, in optimal proportion for a good plasma lipid profile, and are a good source of proteins, rich in proteinogenic amino acids...
April 4, 2018: Food & Function
https://www.readbyqxmd.com/read/29616053/the-aspergillus-flavus-spermidine-synthase-spds-gene-is-required-for-normal-development-aflatoxin-production-and-pathogenesis-during-infection-of-maize-kernels
#10
Rajtilak Majumdar, Matt Lebar, Brian Mack, Rakesh Minocha, Subhash Minocha, Carol Carter-Wientjes, Christine Sickler, Kanniah Rajasekaran, Jeffrey W Cary
Aspergillus flavus is a soil-borne saprophyte and an opportunistic pathogen of both humans and plants. This fungus not only causes disease in important food and feed crops such as maize, peanut, cottonseed, and tree nuts but also produces the toxic and carcinogenic secondary metabolites (SMs) known as aflatoxins. Polyamines (PAs) are ubiquitous polycations that influence normal growth, development, and stress responses in living organisms and have been shown to play a significant role in fungal pathogenesis...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29607667/application-of-multiantigen-profiling-to-detect-pecan
#11
Chung Y Cho, Caroline Puente-Lelievre, Grant D Jones, Sarah R Stadig, Debra A Taylor, Anne C Eischeid, Eric A E Garber
A problem often encountered in the detection and identification of undeclared tree nut food allergens is the lack of analytical methods. This problem is accentuated by the current trend, whereby the primary methods used to detect food allergens are antibody-based enzyme-linked immunosorbent assays (ELISAs) and the development of analyte-specific antibodies takes months. The recently developed xMAP food allergen detection assay (xMAP FADA) has the ability to generate multiantigen profiles with tree nuts, thereby providing a potential solution to this problem...
April 2, 2018: Journal of Food Protection
https://www.readbyqxmd.com/read/29601353/how-to-diagnose-food-allergy
#12
Sakura Sato, Noriyuki Yanagida, Motohiro Ebisawa
PURPOSE OF REVIEW: To assess the recent studies that focus on specific immunoglobulin E (sIgE) testing and basophil activation test (BAT) for diagnosing IgE-mediated food allergies. RECENT FINDINGS: The sIgE to allergen extract or component can predict reactivity to food. The cutoff value based on the positive predictive value (PPV) of sIgE can be considered whenever deciding whether oral food challenge (OFC) is required to diagnose hen's egg, cow's milk, wheat, peanut, and cashew nut allergy...
June 2018: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29594821/tree-nut-peanut-and-peanut-butter-consumption-and-the-risk-of-gastric-and-esophageal-cancer-subtypes-the-netherlands-cohort-study
#13
Lisette Nieuwenhuis, Piet A van den Brandt
BACKGROUND: Nut consumption has been associated with reduced cancer-related mortality. However, it is unclear whether nut consumption also reduces the risk of esophageal and gastric cancer subtypes. We prospectively investigated the relationship of tree nut, peanut, and peanut butter intake with risk of esophageal squamous cell carcinoma (ESCC), esophageal adenocarcinoma (EAC), gastric cardia adenocarcinoma (GCA), and gastric non-cardia adenocarcinoma (GNCA) in the Netherlands Cohort Study...
March 28, 2018: Gastric Cancer
https://www.readbyqxmd.com/read/29582253/development-of-a-droplet-digital-pcr-assay-for-population-analysis-of-aflatoxigenic-and-atoxigenic-aspergillus-flavus-mixtures-in-soil
#14
Sui Sheng T Hua, Jeffrey D Palumbo, Dan E Parfitt, Siov Bouy L Sarreal, Teresa L O'Keeffe
Aflatoxin B1 is a potent hepatotoxin and carcinogen that poses a serious safety hazard to both humans and animals. Aspergillus flavus is the most common aflatoxin-producing species on corn, cotton, peanuts, and tree nuts. Application of atoxigenic strains to compete against aflatoxigenic strains of A. flavus has emerged as one of the most practical strategies for ameliorating aflatoxin contamination in food. Genes directly involved in aflatoxin biosynthesis are clustered on an 82-kb region of the genome. Three atoxigenic strains (CA12, M34, and AF123) were each paired with each of four aflatoxigenic strains (CA28, CA42, CA90, and M52), inoculated into soil and incubated at 28 °C for 2 weeks and 1 month...
March 26, 2018: Mycotoxin Research
https://www.readbyqxmd.com/read/29551198/mycobiota-associated-with-insect-galleries-in-walnut-with-thousand-cankers-disease-reveals-a-potential-natural-enemy-against-geosmithia-morbida
#15
Romina Gazis, Laura Poplawski, William Klingeman, Sarah L Boggess, Robert N Trigiano, Andrew D Graves, Steven J Seybold, Denita Hadziabdic
Thousand Cankers Disease (TCD) affects Juglans and Pterocarya species. This disease poses not only a major threat to the nut and timber industries but also to native stands of walnut trees. Galleries created by Pityophthorus juglandis (vector) are colonized by the fungus Geosmithia morbida (causal agent of necrosis). It is unknown if other fungi colonizing these galleries might act antagonistically towards G. morbida. The objectives of this study were to: (1) characterize the fungal community associated with TCD-infected trees and (2) develop a pilot study addressing their potential antagonism towards G...
April 2018: Fungal Biology
https://www.readbyqxmd.com/read/29542889/allergy-to-ltp-to-eat-or-not-to-eat-sensitizing-foods-a-follow-up-study
#16
R Asero, M Piantanida, V Pravettoni
Background. Follow-up data about the onset of novel food allergies in patients allergic to lipid transfer protein (LTP) are missing. We investigated the occurrence of novel allergies over time in LTP hypersensitive patients. Methods. Sixty-seven LTP-allergic patients recommended to avoid foods responsible for systemic reactions and encouraged to eat other sensitizing foods avoiding the association with known co-factors, were re-evaluated after ≥ 1 year to assess the occurrence of allergy to novel foods. IgE to rPru p 3, rBet v 1, and r Phl p 12 were measured...
February 16, 2018: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29534487/a-pecan-rich-diet-improves-cardiometabolic-risk-factors-in-overweight-and-obese-adults-a-randomized-controlled-trial
#17
Diane L McKay, Misha Eliasziw, C Y Oliver Chen, Jeffrey B Blumberg
Evidence from observational and intervention studies has shown a high intake of tree nuts is associated with a reduced risk of cardiovascular disease (CVD), mortality from type 2 diabetes (T2DM), and all-cause mortality. However, there is limited data regarding their effects on indicators of cardiometabolic risk other than hypercholesterolemia, and little is known about the demonstrable health benefits of pecans ( Carya illinoensis (Wangenh.) K.Koch). We conducted a randomized, controlled feeding trial to compare the effects of a pecan-rich diet with an isocaloric control diet similar in total fat and fiber content, but absent nuts, on biomarkers related to CVD and T2DM risk in healthy middle-aged and older adults who are overweight or obese with central adiposity...
March 11, 2018: Nutrients
https://www.readbyqxmd.com/read/29527645/ion-homeostasis-osmoregulation-and-physiological-changes-in-the-roots-and-leaves-of-pistachio-rootstocks-in-response-to-salinity
#18
Mohammad Akbari, Nasser Mahna, Katam Ramesh, Ali Bandehagh, Silvia Mazzuca
Pistachio, one of the important tree nuts, is cultivated in arid and semi-arid regions where salinity is the most common abiotic stress encountered by this tree. However, the mechanisms underlying salinity tolerance in this plant are not well understood. In the present study, five 1-year-old pistachio rootstocks (namely Akbari, Badami, Ghazvini, Kale-Ghouchi, and UCB-1) were treated with four saline water regimes (control, 8, 12, and 16 dS m-1 ) for 100 days. At high salinity level, all rootstocks showed decreased relative water content (RWC), total chlorophyll content (TCHC), and carotenoids in the leaf, while ascorbic acid (AsA) and total soluble proteins (TSP) were reduced in both leaf and root organs...
March 12, 2018: Protoplasma
https://www.readbyqxmd.com/read/29524559/caregiver-and-expecting-caregiver-support-for-early-peanut-introduction-guidelines
#19
Matthew Greenhawt, Edmond S Chan, David M Fleischer, Allison Hicks, Rachel Wilson, Marcus Shaker, Carina Venter, David Stukus
BACKGROUND: Recent guidelines recommend early peanut introduction (EPI) beginning around 4 to 6 months of age in infants with severe eczema and/or egg allergy and around 6 months for all other infants. Caregiver preferences for such practices are unknown. METHODS: We explored preferences for EPI and in-office allergy risk assessment (IRA) through a nationally representative survey of expecting (n = 1,000) and new caregivers of infants younger than 1 year (n = 1,000)...
March 7, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29489429/nut-consumption-and-survival-in-patients-with-stage-iii-colon-cancer-results-from-calgb-89803-alliance
#20
Temidayo Fadelu, Sui Zhang, Donna Niedzwiecki, Xing Ye, Leonard B Saltz, Robert J Mayer, Rex B Mowat, Renaud Whittom, Alexander Hantel, Al B Benson, Daniel M Atienza, Michael Messino, Hedy L Kindler, Alan Venook, Shuji Ogino, Kimmie Ng, Kana Wu, Walter Willett, Edward Giovannucci, Jeffrey Meyerhardt, Ying Bao, Charles S Fuchs
Purpose Observational studies have reported increased colon cancer recurrence and mortality in patients with states of hyperinsulinemia, including type 2 diabetes, obesity, sedentary lifestyle, and high glycemic load diet. Nut intake has been associated with a lower risk of type 2 diabetes, metabolic syndrome, and insulin resistance. However, the effect of nut intake on colon cancer recurrence and survival is not known. Patients and Methods We conducted a prospective, observational study of 826 eligible patients with stage III colon cancer who reported dietary intake on food frequency questionnaires while enrolled onto a randomized adjuvant chemotherapy trial...
April 10, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
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