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low frequency ultrasound

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https://www.readbyqxmd.com/read/27913777/risk-factors-for-major-bleeding-in-the-seattle-ii-trial
#1
Immad Sadiq, Samuel Z Goldhaber, Ping-Yu Liu, Gregory Piazza
Ultrasound-facilitated, catheter-directed, low-dose fibrinolysis minimizes the risk of intracranial bleeding compared with systemic full-dose fibrinolytic therapy for pulmonary embolism (PE). However, major bleeding is nevertheless a potential complication. We analyzed the 150-patient SEATTLE II trial of submassive and massive PE patients to describe those who suffered major bleeding events following ultrasound-facilitated, catheter-directed, low-dose fibrinolysis and to identify risk factors for bleeding. Major bleeding was defined as GUSTO severe/life-threatening or moderate bleeds within 72 hours of initiation of the procedure...
December 1, 2016: Vascular Medicine
https://www.readbyqxmd.com/read/27910051/ultrasound-targeted-microbubble-destruction-for-cardiac-gene-delivery
#2
Shuyuan Chen, Paul A Grayburn
Ultrasound targeted microbubble destruction (UTMD) is a novel technique that is used to deliver a gene or other bioactive substance to organs of living animals in a noninvasive manner. Plasmid DNA binding with cationic liposome into nanoparticles are assembled into the shell of microbubbles, which are circulated by intravenous injection. Intermittent bursts of ultrasound with low frequency and high mechanical index destroys the microbubbles and releases the nanoparticles into targeted organ to transfect local organ cells...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27908167/computer-aided-prognosis-for-cell-death-categorization-and-prediction-in-vivo-using-quantitative-ultrasound-and-machine-learning-techniques
#3
M J Gangeh, A Hashim, A Giles, L Sannachi, G J Czarnota
PURPOSE: At present, a one-size-fits-all approach is typically used for cancer therapy in patients. This is mainly because there is no current imaging-based clinical standard for the early assessment and monitoring of cancer treatment response. Here, the authors have developed, for the first time, a complete computer-aided-prognosis (CAP) system based on multiparametric quantitative ultrasound (QUS) spectroscopy methods in association with texture descriptors and advanced machine learning techniques...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27903338/-ultrasound-imaging-increases-first-attempt-success-rate-of-neuraxial-block-in-elderly-patients
#4
J Geng, X L Chen, X D Wang, X Y Guo, M Li
Objective: To verify whether preprocedural ultrasound of the lumbar spine could improve first-attempt success rate (defined as a successful neuraxial anesthesia with only one skin puncture) of neuraxial block in elderly patients. Methods: From septemble 2015 to February 2016, 200 elderly patients undergoing lower-limb surgery with neuraxial block at the Peking Universty Third Hospital were enrolled in this study.RandA 1.0 software was used to randomize patients into two groups: conventional surface landmark-guided group (group LM) and ultrasound-assisted group (group US)...
November 22, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27902494/an-ultrasound-look-at-korotkoff-sounds-the-role-of-pulse-wave-velocity-and-flow-turbulence
#5
Amir Benmira, Antonia Perez-Martin, Iris Schuster, Florent Veye, Jean Triboulet, Nicolas Berron, Isabelle Aichoun, Sarah Coudray, Jérémy Laurent, Fethi Bereksi-Reguig, Michel Dauzat
AIMS: The aim of this study was to analyze the temporal relationships between pressure, flow, and Korotkoff sounds, providing clues for their comprehensive interpretation. MATERIALS AND METHODS: When measuring blood pressure in a group of 23 volunteers, we used duplex Doppler ultrasonography to assess, under the arm-cuff, the brachial artery flow, diameter changes, and local pulse wave velocity (PWV), while recording Korotkoff sounds 10 cm downstream together with cuff pressure and ECG...
November 29, 2016: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/27883051/lipid-coated-microbubbles-and-low-intensity-pulsed-ultrasound-enhance-chondrogenesis-of-human-mesenchymal-stem-cells-in-3d-printed-scaffolds
#6
Mitra Aliabouzar, Lijie Grace Zhang, Kausik Sarkar
Lipid-coated microbubbles are used to enhance ultrasound imaging and drug delivery. Here we apply these microbubbles along with low intensity pulsed ultrasound (LIPUS) for the first time to enhance proliferation and chondrogenic differentiation of human mesenchymal stem cells (hMSCs) in a 3D printed poly-(ethylene glycol)-diacrylate (PEG-DA) hydrogel scaffold. The hMSC proliferation increased up to 40% after 5 days of culture in the presence of 0.5% (v/v) microbubbles and LIPUS in contrast to 18% with LIPUS alone...
November 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27871685/comparison-of-ultrasound-frequency-in-laryngeal-ultrasound-for-vocal-cord-evaluation
#7
Jung-Woo Woo, Inhye Park, Jun Ho Choe, Jung-Han Kim, Jee Soo Kim
BACKGROUND: Laryngeal ultrasound is a new method of vocal cord evaluation in patients at risk for vocal cord palsy. However, the previously described laryngeal ultrasound reportedly has a high failure rate of vocal cord visualization in male patients. We compared 2 ultrasound frequencies in laryngeal ultrasound to improve on the limitations of this method. METHOD: A total of 301 (55 male, 246 female) consecutive laryngeal ultrasound and direct laryngoscopy exams were performed for patients with thyroidectomy and other neck operations...
November 18, 2016: Surgery
https://www.readbyqxmd.com/read/27867723/all-optical-highly-sensitive-akinetic-sensor-for-ultrasound-detection-and-photoacoustic-imaging
#8
Stefan Preisser, Wolfgang Rohringer, Mengyang Liu, Christian Kollmann, Stefan Zotter, Balthasar Fischer, Wolfgang Drexler
A novel all-optical akinetic ultrasound sensor, consisting of a rigid, fiber-coupled Fabry-Pérot etalon with a transparent central opening is presented. The sensing principle relies exclusively on the detection of pressure-induced changes of the refractive index in the fluid filling the Fabry-Pérot cavity. This enables resonance-free, inherently linear signal detection over a broad bandwidth. We demonstrate that the sensor achieves a exceptionally low peak noise equivalent pressure (NEP) values of 2 Pa over a 20 MHz measurement bandwidth (without signal averaging), while maintaining a flat frequency response, and a detection bandwidth up to 22...
October 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27863786/preoperative-detection-of-ras-mutation-may-guide-extent-of-thyroidectomy
#9
Snehal G Patel, Sally E Carty, Kelly L McCoy, N Paul Ohori, Shane O LeBeau, Raja R Seethala, Marina N Nikiforova, Yuri E Nikiforov, Linwah Yip
BACKGROUND: Preoperative detection of RAS mutations can contribute to cancer risk assessment in indeterminate thyroid nodules, although RAS is not always associated with malignancy. METHODS: Fine-needle aspiration samples classified in 1 of 3 indeterminate cytology categories were prospectively tested for N-, H-, and K-RAS mutations using next-generation sequencing assay. RESULTS: In the study, 93 patients with 94 nodules had preoperative RAS detected, of whom 86 patients had an operation (69% total thyroidectomy, 29% lobectomy)...
November 15, 2016: Surgery
https://www.readbyqxmd.com/read/27858670/viscoelastic-properties-of-normal-rat-liver-measured-by-ultrasound-elastography-comparison-with-oscillatory-rheometry
#10
Haoming Lin, Yuanyuan Shen, Xin Chen, Ying Zhu, Yi Zheng, Xinyu Zhang, Yanrong Guo, Tianfu Wang, Siping Chen
BACKGROUND: Ultrasound elastography has been widely used to measure liver stiffness. However, the accuracy of liver viscoelasticity obtained by ultrasound elastography has not been well established. OBJECTIVE: To assess the accuracy of ultrasound elastography for measuring liver viscoelasticity and compare to conventional rheometry methods. In addition, to determine if combining these two methods could delineate the rheological behavior of liver over a wide range of frequencies...
November 14, 2016: Biorheology
https://www.readbyqxmd.com/read/27853727/effects-of-low-intensity-continuous-ultrasound-on-hematological-parameters-of-rats
#11
M Mehrpour, A Shakeri-Zadeh, P Basir, B Jamei, H Ghaheri, M B Shiran
BACKGROUND: Low intensity ultrasound (US) has some well-known bio-effects which are of great importance to be considered. Objective: We conducted the present study to investigate the effects of low intensity continuous ultrasound on blood cells count in rat. METHODS: Rats were anesthetized and blood samples were collected before US exposure. Then, they were exposed to US with nominal intensity of 0.2 W/cm2 at frequency of 3 MHz for a period of 10 minutes and this protocol was repeated for 7 days...
September 2016: Journal of Biomedical Physics & Engineering
https://www.readbyqxmd.com/read/27845219/efficacy-of-daily-low-dose-tadalafil-for-treating-overactive-bladder-results-of-a-randomized-double-blind-placebo-controlled-trial
#12
Hongde Chen, Feng Wang, Zhixian Yu, Yirong Zhang, Chaohui Liu, Shengjie Dai, Bicheng Chen, Jiaju Lv
OBJECTIVES: To evaluate the efficacy of daily low-dose tadalafil therapy for overactive bladder (OAB) in women. PATIENTS AND METHODS: A total of 96 women with idiopathic OAB from three medical centers in the south of Zhejiang Province of China were randomly assigned to treatment with daily low-dose tadalafil (5 mg, n=48) or placebo (n=48) for 3 months. The Indevus urgency severity scale (IUSS), overactive bladder symptom score (OABSS),([2]) and a 3-day micturition diary with frequency, incontinence, and urgency episodes were recorded and compared before the treatment, every 2 weeks following the treatment, and 3 months after the treatment...
November 11, 2016: Urology
https://www.readbyqxmd.com/read/27842834/some-factors-affecting-efficiency-of-the-ultrasound-aided-enzymatic-hydrolysis-of-cotton-cellulose
#13
Orsolya Erzsebet Szabo, Emilia Csiszar
The efficiency of the enzymatic hydrolysis of cellulose with low frequency ultrasound (horn-type reactor) was investigated and characterized by the concentration of reducing sugars liberated. Small squares of bleached cotton fabric were used for comparing the efficiency of different agitation methods (i.e. magnetic stirring, horizontal and vertical mechanical agitation) and ultrasound. At the same enzyme dosage and substrate level, sonication at 40, 60 and 80% amplitudes (Idiss: 16.2, 32.2 and 43.4W/cm(2), respectively) intensified the hydrolysis over the most efficient mechanical agitation (i...
January 20, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27834651/spread-spectrum-photoacoustic-tomography-with-image-optimization
#14
Meng Cao, Ting Feng, Jie Yuan, Guan Xu, Xueding Wang, Paul L Carson
Photoacoustic tomography (PAT) of biological tissue offers potential advantages in distinguishing different structures according to their chemical composition. However, as medical photoacoustic (PA) signals are broad band, which usually cover a 0.2-50 MHz range, current band-limited ultrasound transducers can only receive and present a limited fraction of that range. Besides, the received PA signals are usually of low signal-to-noise ratio (SNR), which further deteriorates the image quality. Therefore, the goal of this work is to recover the out-of-band frequency components in the received PA signals based on a best estimate of the frequency response of the ultrasound transducers, and to improve the PA image quality...
November 4, 2016: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/27826539/vertical-small-needle-caudal-epidural-injection-technique
#15
Liza Maniquis Smigel, Kenneth Dean Reeves, Howard Jeffrey Rosen, David Patrick Rabago
BACKGROUND: Anecdotal evidence suggests that a vertical small-needle injection method enters the caudal epidural space with comparable efficacy to cephalad-directed methods, with less intravascular injection. OBJECTIVES: Assess the success rate of vertical caudal epidural injection using epidurography and the frequency of intravascular injection using a vertical small-needle approach. PATIENTS AND METHODS: Participants had chronic generalized non-surgical low back pain and either gluteal and/or leg pain and were enrolled in a simultaneous clinical trial assessing the analgesic effect of 5% dextrose epidural injection...
June 2016: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/27824560/assessing-the-performance-of-ultrafast-vector-flow-imaging-in-the-neonatal-heart-via-multiphysics-modeling-and-in-vitro-experiments
#16
Joris Van Cauwenberge, Lasse Lovstakken, Solveig Fadnes, Alfonso Rodriguez-Morales, Jan Vierendeels, Patrick Segers, Abigail Swillens
Ultrafast vector flow imaging would benefit newborn patients with congenital heart disorders, but still requires thorough validation before translation to clinical practice. This paper investigates 2-D speckle tracking (ST) of intraventricular blood flow in neonates when transmitting diverging waves at ultrafast frame rate. Computational and in vitro studies enabled us to quantify the performance and identify artifacts related to the flow and the imaging sequence. First, synthetic ultrasound images of a neonate's left ventricular flow pattern were obtained with the ultrasound simulator Field II by propagating point scatterers according to 3-D intraventricular flow fields obtained with computational fluid dynamics (CFD)...
November 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27824559/a-comparison-between-compounding-techniques-using-large-beam-steered-plane-wave-imaging-for-blood-vector-velocity-imaging-in-a-carotid-artery-model
#17
Anne E C M Saris, Hendrik H G Hansen, Stein Fekkes, Maartje M Nillesen, Marcel C M Rutten, Chris L de Korte
Conventional color Doppler imaging is limited, since it only provides velocity estimates along the ultrasound beam direction for a restricted field of view at a limited frame rate. High-frame-rate speckle tracking, using plane wave transmits, has shown potential for 2-D blood velocity estimation. However, due to the lack of focusing in transmit, image quality gets reduced, which hampers speckle tracking. Although ultrafast imaging facilitates improved clutter filtering, it still remains a major challenge in blood velocity estimation...
November 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27816441/kinetics-of-inactivation-and-photoreactivation-of-escherichia-coli-using-ultrasound-enhanced-uv-c-light-emitting-diodes-disinfection
#18
Xiaoqin Zhou, Zifu Li, Juanru Lan, Yichang Yan, Nan Zhu
Ultraviolet (UV) disinfection is highly recommended owing to its high disinfection efficiency and disinfection by-products free, and UV Light-Emitting Diodes (UV LEDs) is increasingly becoming an alternative of mercury UV lamps for water disinfection owing to its long lifetime, low input power, and absence of problems on disposal. However, renovation of existing UV lamps faces the challenges for UV disinfection associated with disinfection efficiency and photoreactivation, and modified UV disinfection process is required for practical application...
March 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/27810806/evaluation-of-the-transverse-oscillation-technique-for-cardiac-phased-array-imaging-a-theoretical-study
#19
Brecht Heyde, Nick Bottenus, Jan D'hooge, Gregg E Trahey
The transverse oscillation (TO) technique can improve the estimation of tissue motion perpendicular to the ultrasound beam direction. TOs can be introduced using plane wave (PW) insonification and bi-lobed Gaussian apodisation (BA) on receive (abbreviated as PWTO). Furthermore, the TO frequency can be doubled after a heterodyning demodulation process is performed (abbreviated as PWTO*). This study is concerned with identifying the limitations of the PWTO technique in the specific context of myocardial deformation imaging with phased arrays and investigating the conditions in which it remains advantageous over traditional focused (FOC) beamforming...
October 28, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27787782/superharmonic-imaging-for-medical-ultrasound-a-review
#20
Narendra D Londhe, Jasjit S Suri
Ultrasound with harmonics has emerged as an exceptional alternative to competitively low resolution fundamental ultrasound imaging. The use of second harmonic is already a trend now but higher harmonics are also being seen as even better option due to its improved resolution. The resolution improved with frequency but achieves penetration of reduced energy. The cumulative addition of higher harmonics during propagation yields higher harmonics giving better resolution with adequate penetration. This paper summarizes the progress of such similar decade old harmonic ultrasound imaging technique i...
December 2016: Journal of Medical Systems
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