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https://www.readbyqxmd.com/read/27909035/randomised-controlled-pilot-study-to-investigate-the-effectiveness-of-thoracic-epidural-and-paravertebral-blockade-in-reducing-chronic-post-thoracotomy-pain-topic-feasibility-study-protocol
#1
Joyce Yeung, Teresa Melody, Amy Kerr, Babu Naidu, Lee Middleton, Kostas Tryposkiadis, Jane Daniels, Fang Gao
INTRODUCTION: Open chest surgery (thoracotomy) is considered the most painful of surgical procedures. Forceful wound retraction, costochondral dislocation, posterior costovertebral ligament disruption, intercostal nerve trauma and wound movement during respiration combine to produce an acute, severe postoperative pain insult and persistent chronic pain many months after surgery is common. Three recent systematic reviews conclude that unilateral continuous paravertebral blockade (PVB) provides analgesia at least equivalent to thoracic epidural blockade (TEB) in the postoperative period, has a lower failure rate, and symptom relief that lasted months...
December 1, 2016: BMJ Open
https://www.readbyqxmd.com/read/27908143/efficient-molecular-quantum-dynamics-in-coordinate-and-phase-space-using-pruned-bases
#2
H R Larsson, B Hartke, D J Tannor
We present an efficient implementation of dynamically pruned quantum dynamics, both in coordinate space and in phase space. We combine the ideas behind the biorthogonal von Neumann basis (PvB) with the orthogonalized momentum-symmetrized Gaussians (Weylets) to create a new basis, projected Weylets, that takes the best from both methods. We benchmark pruned time-dependent dynamics using phase-space-localized PvB, projected Weylets, and coordinate-space-localized DVR bases, with real-world examples in up to six dimensions...
November 28, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/27858290/complete-sequence-and-variability-of-a-new-subgroup-b-nepovirus-infecting-potato-in-central-peru
#3
Joao De Souza, Giovanna Müller, Wilmer Perez, Wilmer Cuellar, Jan Kreuze
The complete bipartite genome (RNA1 and RNA2) of a new nepovirus infecting potato was obtained using small RNA sequencing and assembly complemented by Sanger sequencing. Each RNA encodes a single polyprotein, flanked by 5' and 3' untranslate regions (UTR) and followed by a poly (A) tail. The putative polyproteins encoded by RNA1 and RNA2 had sets of motifs which are characteristic of viruses in the genus Nepovirus. Sequence comparisons using the Pro-Pol region and the coat protein, including phylogenetic analysis of these regions, showed closest relationships with nepoviruses...
November 17, 2016: Archives of Virology
https://www.readbyqxmd.com/read/27742320/organ-donation-and-transplantation-from-donors-with-systemic-infection-a-single-center-experience
#4
X Yuan, C Chen, J Zhou, M Han, X Wang, C Wang, X He
OBJECTIVES: Donors with bacteremia and sepsis are often considered to be controversial for organ retrieval due to potential transmission of an infectious agent to the recipient. Herein we report our initial experience of organ donation and transplantation results from donors with systemic infection. MATERIALS AND METHODS: From January 2013 to December 2014, 125 cases of donation were completed in our organ procurement organization including 90 cases of donation after brain death (DBD) and 35 cases of donation after circulatory death (DCD)...
September 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27685344/the-impact-of-paravertebral-block-analgesia-on-breast-cancer-survival-after-surgery
#5
Juan P Cata, Mariana Chavez-MacGregor, Vicente Valero, Walter Black, Daliah M Black, Farzin Goravanchi, Ifey C Ifeanyi, Mike Hernandez, Andrea Rodriguez-Restrepo, Vijaya Gottumukkala
BACKGROUND AND OBJECTIVES: The impact of regional anesthesia on breast cancer recurrence is controversial. We tested the hypothesis that the use of paravertebral block (PVB) analgesia during breast cancer surgery prolongs the recurrence-free survival (RFS) and overall survival (OS) of women with breast cancer. METHODS: Seven hundred ninety-two women with nonmetastatic breast cancer were included in this retrospective study. Patients were divided based on the administration of PVB analgesia for mastectomy surgeries...
September 28, 2016: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/27586312/-thoracic-paravertebral-block-in-patients-ineligible-for-epidural-block
#6
Hideaki Kojima, Mitsuhiro Isaka, Yoshiyuki Yasuura, Reiko Shimizu, Hiroyuki Kayata, Shoji Takahashi, Eiji Ando, Yasuhisa Ohde
We retrospectively assessed the effectiveness and the safety of thoracic paravertebral block(PVB) in patients ineligible for epidural block (EP). Eleven PVB patients and 33 EP patients were enrolled. Postoperative pain was evaluated using a numerical rating scale (NRS). The mean NRS ± standard deviation at rest 24 and 48 hours after surgery were 1.36 ± 1.63 and 0.55 ± 1.03 in the PVB group and 1.07 ± 1.47 and 1.38 ± 1.31 in the EP group, respectively. There were no statistically significant differences in the NRS scores...
September 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/27518726/retrolaminar-block-analgesic-efficacy-and-safety-evaluation
#7
Takeshi Murouchi, Michiaki Yamakage
PURPOSE: Retrolaminar block (RLB) is a thoracic truncal block that can produce analgesia for the thoracic and abdominal wall. However, the characteristics of RLB are not well known. The aim of this study was to determine analgesic efficacy by measuring postoperative consume of patient-controlled analgesia (PCA), additional nonsteroidal antiinflammatory drug (NSAID) rescue, and opioid rescue. Our secondary analysis included assessment of the chronological change in arterial levobupivacaine concentrations after the block...
August 12, 2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/27512167/the-comparative-evaluation-of-safety-and-efficacy-of-unilateral-paravertebral-block-with-conventional-spinal-anaesthesia-for-inguinal-hernia-repair
#8
Sunil Kumar Sinha, Yudhyavir Brahmchari, Manpreet Kaur, Aruna Jain
BACKGROUND AND AIMS: Unilateral paravertebral block (PVB) as a sole anaesthetic technique is underutilised even in experienced hands. Hence, this study was undertaken regarding the efficacy and safety of PVB and compared with subarachnoid block (SAB) for inguinal hernia repair procedures. METHODS: Sixty-three consenting adult male patients scheduled for unilateral inguinal hernia repair were randomly assigned to receive either PVB or SAB (Group P: PVBs at T10-L2 levels, 5 mL of 0...
July 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/27489056/preoperative-paravertebral-block-improves-postoperative-pain-control-and-reduces-hospital-length-of-stay-in-patients-undergoing-autologous-breast-reconstruction-after-mastectomy-for-breast-cancer
#9
Rajiv P Parikh, Ketan Sharma, Ryan Guffey, Terence M Myckatyn
BACKGROUND: Postoperative pain is a major challenge for patients undergoing breast reconstruction after surgical treatment of breast cancer, resulting in prolonged hospitalizations and additional resource utilization. Evidence on the efficacy of techniques to minimize postoperative pain in autologous breast reconstruction is lacking. We sought to determine whether preoperative paravertebral block (PVB), a regional anesthetic technique, affects postoperative pain control and hospital length of stay (LOS) in patients undergoing autologous breast reconstruction...
December 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27410841/squeezed-hollow-core-photonic-bragg-fiber-for-surface-sensing-applications
#10
Jingwen Li, Hang Qu, Maksim Skorobogatiy
We propose to use squeezed hollow-core photonic bandgap Bragg fibers for surface sensing applications. We demonstrate theoretically and confirm experimentally that squeezing a section of the Bragg fiber core increases overlap between the optical fields of the core guided modes and the modes bound to the sensing layer, thus, significantly enhancing their interaction via anticrossing phenomenon, which, in turn, enhances surface sensitivity of the fiber sensor. As a practical demonstration, we apply our fiber sensor to in situ monitoring of the dissolution dynamics of a sub-micron-thick polyvinyl butyral (PVB) film coated on the surface of the liquid-filled Bragg fiber core...
July 11, 2016: Optics Express
https://www.readbyqxmd.com/read/27389472/functional-analysis-and-intervention-for-perseverative-verbal-behaviour-of-an-older-adult-with-traumatic-brain-injury
#11
Amy Garcia Quearry, Duane A Lundervold
OBJECTIVE: A functional analysis of behaviour was conducted to determine the controlling variables related to the perseverative verbal behaviour (PBV) of a 60-year-old female with a long-standing traumatic brain injury receiving educational assistance. METHOD: Functional analyses (FA) of antecedent and consequent conditions related to PCB were conducted to determine controlling influence of: (a) content of verbal interaction and, (b) social reinforcement. After isolating the controlling variables, the functioned-based intervention was implemented in 60 minute tutoring sessions...
2016: Brain Injury: [BI]
https://www.readbyqxmd.com/read/27323125/tiaogan-qingxin-granule-treatment-increases-myocardial-connexin-43-expression-in-a-rat-model-of-arrhythmia
#12
J H Yao, C H Qu, L Ma, X Z Chang
Myocardial ischemia-induced arrhythmia, especially ventricular arrhythmia, is the main reason for sudden cardiac death. Therefore, ischemic ventricular arrhythmia-targeted treatments are urgently needed. The mechanism of Tiaogan Qingxin Granule in premature ventricular beat (PVB) treatment was explored in arrhythmic rats pretreated with Tiaogan Qingxin Granule. Sprague-Dawley rats (N = 40) were randomly divided into 4 groups: sham-operated, arrhythmia model, Wenxin Granule, and Tiaogan Qingxin Granule. The ischemic arrhythmia model was established by ligating the left anterior descending coronary artery...
2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27253660/a-new-formulation-of-oral-viscous-budesonide-in-treating-of-paediatric-eosinophilic-oesophagitis-a-pilot-study
#13
Salvatore Oliva, Danilo Rossetti, Paola Papoff, Antonio Tiberti, Paolo Rossi, Sara Isoldi, Jorge Amil Dias, Sandra Lucarelli, Salvatore Cucchiara
BACKGROUND: Oral Viscous Budesonide (OVB) is a recent therapeutic option for Eosinophilic Oesophagitis (EoE) versus dietary restriction and inhaled steroids. This single center, open label, not blinded study aims to evaluate the efficacy and safety of a new, pre-prepared oral viscous budesonide suspension (PVB) in children and adolescents with EoE. METHODS: We treated with PVB 36 children (29 male; median age 12 years) with EoE diagnosed according to ESPGHAN guidelines...
June 2, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27235636/cognitive-impairment-effects-of-early-life-stress-in-adolescents-can-be-predicted-with-early-biomarkers-impacts-of-sex-experience-and-cytokines
#14
Rodrigo Grassi-Oliveira, Jennifer A Honeycutt, Freedom H Holland, Prabarna Ganguly, Heather C Brenhouse
Childhood adversity increases vulnerability to psychiatric disorders that emerge in adolescence, in a sex-dependent manner. Early adversity modeled in rodents with maternal separation (MS) affects cognition and medial prefrontal cortex (mPFC) circuitry. Humans and animals exposed to early life adversity also display heightened circulating inflammatory cytokines, however the predictive relationship of these early measures with later behavioral deficits is unknown. Here, male and female rats were exposed to MS or control rearing during the postnatal period (P2-21)...
September 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27108128/ct-guided-paravertebral-block-for-microwave-ablation-of-kidney-tumors-a-new-technique
#15
Jonathan Dubut, Bruno Kastler, Eric Delabrousse, Charlee Nardin, Julien Chenet, François Kleinclauss, Sébastien Aubry
PURPOSE: In patients undergoing computed tomography (CT)-guided microwave ablation (MWA) for renal tumors, we developed a CT-guided anterior paravertebral block (PVB) associated with anesthesia of the kidney capsule and inhalation of an equimolar mixture of oxygen and nitrous oxide (EMONO). The primary objectives were to describe our technique and to study its efficacy in terms of procedural success. The secondary objective was to study the tolerance by evaluating patient pain scores and the number of complications...
June 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27043787/application-of-continuous-wound-infusion-catheters-in-lung-transplantation-a-retrospective-data-analysis
#16
Nils Lenz, Markus Hirschburger, Rainer Roehrig, Thilo Menges, Matthias Mueller, Winfried Padberg, Valesco Mann
Background Lung transplantation is the only treatment option for many patients with end-stage pulmonary disease. Therefore, postthoracotomy pain therapy is of vital interest. Thoracic epidural analgesia (EPI) is the "gold standard" for postthoracotomy pain, but especially in lung transplantation contraindications, and potential infectious complications limit its advantages. Under these circumstances surgically placed postthoracotomy catheter-assisted continuous paravertebral intercostal nerve block (PVB) could be of advantage...
April 4, 2016: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/27037505/the-prevalence-and-clinical-significance-of-premature-ventricular-beats-in-the-athlete
#17
F D'Ascenzi, A Zorzi, F Alvino, M Bonifazi, D Corrado, S Mondillo
Adolescents and adults with cardiovascular disease who are engaged in sports activity have an increased risk of sudden cardiac death (SCD) that is three times greater than that of their non-athletic counterparts. Sport acts as a trigger for cardiac arrest in the presence of underlying cardiovascular diseases predisposing to life-threatening ventricular arrhythmias. Frequent and complex premature ventricular beats (PVBs) detected during the cardiovascular screening of the athletic population may be a sign of an underlying cardiovascular disease at risk of SCD, but are also often recorded in trained athletes without cardiovascular abnormalities...
March 31, 2016: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/27029747/tailored-therapy-and-long-term-surveillance-of-malignant-germ-cell-tumors-in-the-female-genital-system-10-year-experience
#18
Qianying Zhao, Jiaxin Yang, Dongyan Cao, Jiangna Han, Kaifeng Xu, Yongjian Liu, Keng Shen
OBJECTIVE: To explore the appropriate treatment of malignant germ cell tumor (MGCT) in the female genital system, and to analyze the factors influencing both therapeutic response and survival outcome. METHODS: A cohort of 230-Chinese women diagnosed with MGCT of the genital system was retrospectively reviewed and prospectively followed. The demographic and pathological features, extent of disease and surgery, treatment efficiency, recurrence and survival were analyzed...
May 2016: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/27009436/waterborne-chitosan-epoxysilane-hybrid-pretreatments-for-corrosion-protection-of-zinc
#19
Christian Fernández-Solis, Andreas Erbe
Biopolymer-based systems are extensively studied as green alternatives for traditional polymer coatings, e.g., in corrosion protection. Chitosan-epoxysilane hybrid films are presented in this work as a chitosan-based protective system, which could, e.g., be applied in a pretreatment step. For the preparation of the chitosan-epoxysilane hybrid systems, a sol-gel procedure was applied. The function of the silane is to ensure adhesion to the substrate. On zinc substrates, homogeneous thin films with thickness of 50-70 nm were obtained after thermal curing...
June 2016: Biointerphases
https://www.readbyqxmd.com/read/26977715/quantum-dynamics-in-phase-space-using-projected-von-neumann-bases
#20
Shai Machnes, Elie Assémat, Henrik R Larsson, David J Tannor
We describe the mathematical underpinnings of the biorthogonal von Neumann method for quantum mechanical simulations (PvB). In particular, we present a detailed discussion of the important issue of nonorthogonal projection onto subspaces of biorthogonal bases, and how this differs from orthogonal projection. We present various representations of the Schrödinger equation in the reduced basis and discuss their relative merits. We conclude with illustrative examples and a discussion of the outlook and challenges ahead for the PvB representation...
May 19, 2016: Journal of Physical Chemistry. A
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