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https://www.readbyqxmd.com/read/28179271/childhood-cancer-type-1-diabetes-and-other-immune-diseases-healthcare-visits-in-the-year-before-diagnosis-in-taiwan
#1
TienYu Owen Yang, Wan-Ting Huang, Mei-Huei Chen, Kuan-Ying Arthur Huang, Pau-Chung Chen
BACKGROUND: Children with cancer, type 1 diabetes and other immune diseases often present initially with non-specific problems. It is unknown how long children with these conditions seek medical help before a diagnosis is reached. METHODS: During the period 2002 to 2013, 7238 children aged 2-15 years diagnosed with cancer at seven sites, type 1 diabetes, and three other immune diseases were registered in the Taiwan National Health Insurance Catastrophic Illness Database...
February 8, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28121975/international-epidemiological-differences-in-acute-poisonings-in-pediatric-emergency-departments
#2
Santiago Mintegi, Beatriz Azkunaga, Javier Prego, Nadeem Qureshi, Stuart R Dalziel, Eunate Arana-Arri, Yordana Acedo, Lorea Martinez-Indart, Arantza Urkaregi, Nerea Salmon, Javier Benito, Nathan Kuppermann
BACKGROUND AND OBJECTIVE: Identifying international differences in the epidemiology of acute poisonings in children may help in improving prevention. We sought to evaluate the international epidemiological differences in acute poisonings in children presenting to emergency departments (EDs) from 8 different global regions. METHODS: This was an international multicenter cross-sectional prospective study including children younger than 18 years with acute poisonings presenting to 105 EDs in 20 countries was conducted...
24, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28105621/-analysis-of-risk-factors-for-bone-metastasis-after-radical-resection-of-colorectal-cancer-within-5-years
#3
Ang Li, Zhen Tan, Chuangang Fu, Hao Wang, Jie Yuan
OBJECTIVE: To investigate the risk factors of metachronous bone metastasis after radical resection of colorectal cancer within 5 years. METHODS: Clinical data of 1 749 patients with colorectal cancer, of whom 50(2.8%) patients developed metastasis to bone after operation, in the Department of Colorectal Surgery, Changhai Hospital of The Second Military Medical University from January 2001 to December 2010 were analyzed retrospectively. Univariate and multivariate analysis were performed to find the risk factors of metachronous bone metastasis from colorectal cancer using Chi square test and Logistic regression, respectively...
January 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28095574/managing-occupational-irritant-contact-dermatitis-using-a-two-step-skincare-regimen-designed-to-prevent-skin-damage-and-support-skin-recovery
#4
Erika C von Grote, Kiruthi Palaniswarmy, Matthew H Meckfessel
Occupational irritant contact dermatitis (ICD) affecting the hands is a common and difficult-to-manage condition. Occupations that necessitate contact with harsh chemicals, use of alcohol-based disinfectants, and frequent hand washing elevate the risk of ICD. Management strategies that do not adequately prevent accumulated damage and repair skin, can develop into chronic dermatoses which negatively impact work productivity and quality of life. A 2-step skin-care regimen (Excipial Daily Protection Hand Cream (EP) and Excipial Rapid Repair Hand Cream (ER), Galderma Laboratories, L...
December 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28092274/power-profiles-and-in-vitro-optical-quality-of-scleral-contact-lenses-effect-of-the-aperture-and-power
#5
Alberto Domínguez-Vicent, Jose Juan Esteve-Taboada, Alberto Recchioni
OBJECTIVE: To assess the power profile and in vitro optical quality of scleral contact lenses with different powers as a function of the optical aperture. METHODS: The mini and semiscleral contact lenses (Procornea) were measured for five powers per design. The NIMO TR-1504 (Lambda-X) was used to assess the power profile and Zernike coefficients of each contact lens. Ten measurements per lens were taken at 3- and 6-mm apertures. Furthermore, the optical quality of each lens was described in Zernike coefficients, modulation transfer function, and point spread function (PSF)...
January 13, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28077150/the-equity-of-china-s-emergency-medical-services-from-2010-2014
#6
Ke Yan, Yi Jiang, Jingfu Qiu, Xiaoni Zhong, Yang Wang, Jing Deng, Jingxi Lian, Tingting Wang, Cheng Cao
BACKGROUND: With the depth development of health care system reform in China, emergency medical services (EMS) is confronted with challenges as well as opportunities. This study aimed to analyze the equity of China's EMS needs, utilization, and resources distribution, and put forward proposal to improve the equity. METHOD: Three emergency needs indicators (mortality rate of cardiovascular and cerebrovascular diseases, harm, and digestive system disease), two utilization indicators (emergency outpatient visits and rate of utilization) and one resource allocation indicator (number of EMS facilities) were collected after the review of the China Statistical Yearbook and the National Disease Surveillance System...
January 11, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28072434/remiss-med-bild-%C3%A2-j%C3%A3-mlik-och-kostnadseffektiv-v%C3%A3-rd-kortare-tid-till-diagnos-och-f%C3%A3-rre-l%C3%A3-nga-patientresor
#7
Nirina Andersson, Anna Preisler-Häggqvist, Virginia Zazo Hernanz
This study evaluates the use of teledermatology at Norrland University Hospital in Northern Sweden between 2009 and 2014. In total, there were 27 198 incoming referrals. Of these, 1504 had photo attachments, and could be answered directly without a face-to-face appointment. Most of these referrals (73%) came from health care providers more than 100 kilometres away and 71% were answered within a week. Patients received care sooner and saved both time and money by less travelling. Teledermatology lead to less delay to a face-to-face appointment for patients where teledermatology was not an option...
January 9, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28065877/charles-estienne-1504-1564-his-life-work-and-contribution-to-anatomy-and-the-first-description-of-the-canal-in-the-spinal-cord
#8
REVIEW
Konstantinos Markatos, Demetrios Chytas, Demetrios Korres, Konstantinos Laios, Georgios Androutsos, Efstathios Chronopoulos
The purpose of this historic review is to summarize the life, work and contribution to anatomy of Charles Estienne (also known by the Latin name Carolus Stephanus). Charles Estienne was an early exponent of the science of anatomy in France. Although he remained under the influence of the Galenic tradition of medicine, anatomy and surgery throughout his distinguished career, he had a significant influence on the scientific revolution and anatomy reformation of the 16th century. Nevertheless he cannot be place in the same level of contribution as Vesalius due to his lack of discipline in his work, hesitation to diverge totally from traditional beliefs and his hesitation for a total criticism of the Galenic tradition...
January 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28032063/carcinogen-risk-assessment-of-polycyclic-aromatic-hydrocarbons-in-drinking-water-using-probabilistic-approaches
#9
Hamid Karyab, Masud Yunesian, Simin Nasseri, Noushin Rastkari, Amirhosein Mahvi, Ramin Nabizadeh
BACKGROUND: This study was focused on the probability of carcinogen risk of low-level ingestion and dermal exposure with polycyclic aromatic hydrocarbons (PAHs) from drinking water in Tehran, capital of Iran. METHODS: Concentrations of 16 PAHs were measured in the tap, bottled and heated tap water in four different seasons. Using a questionnaire-based survey, exposure with PAHs from drinking water was evaluated via direct ingestion, swimming, washing and showering...
November 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27934664/which-way-to-lean-a-national-study-of-women-dental-faculty-members-career-aspirations-and-choices
#10
Cynthia C Gadbury-Amyot, Marsha A Pyle, Christopher J Van Ness, Pamela R Overman, Karen P West
The aim of this first national study of women in academic dentistry was to explore factors and perceived barriers for why administrative/leadership positions were or were not sought via data collected from full-time women dental faculty members in the U.S. In fall 2015, the researchers conducted a survey that employed a combination of response formats: forced choice from a menu, multiple allowable answers, and open-ended written comments. The overall response rate for the survey was 35.6% (537/1504). Respondents were from 48 of the 65 U...
December 2016: Journal of Dental Education
https://www.readbyqxmd.com/read/27900543/stroke-6th-edition-pathophysiology-diagnosis-and-management-by-james-c-grotta-gregory-w-albers-joseph-p-broderick-scott-e-kasner-eng-h-lo-a-david-mendelow-ralph-l-sacco-and-lawrence-k-s-wong-2016-1504-pages-us-405-00-hardcover-isbn-9780323295444-elsevier
#11
https://www.readbyqxmd.com/read/27851140/1504-4f-pcc-demonstrates-favorable-safety-profile-in-a-rabbit-model-of-venous-thrombosis
#12
Eva Herzog, Franz Kaspereit, Wilfried Krege, Baerbel Doerr, Marcel Mischnik, Ingo Pragst, Gerhard Dickneite
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27803225/should-syndesmotic-screws-be-removed-after-surgical-fixation-of-unstable-ankle-fractures-a-systematic-review
#13
REVIEW
S A Dingemans, S Rammelt, T O White, J C Goslings, T Schepers
AIMS: In approximately 20% of patients with ankle fractures, there is an concomitant injury to the syndesmosis which requires stabilisation, usually with one or more syndesmotic screws. The aim of this review is to evaluate whether removal of the syndesmotic screw is required in order for the patient to obtain optimal functional recovery. MATERIALS AND METHODS: A literature search was conducted in Medline, Embase and the Cochrane Library for articles in which the syndesmotic screw was retained...
November 2016: Bone & Joint Journal
https://www.readbyqxmd.com/read/27726379/measurement-of-pre-existing-igg-and-igm-antibodies-against-polyethylene-glycol-in-healthy-individuals
#14
Bing-Mae Chen, Yu-Cheng Su, Chia-Jung Chang, Pierre-Alain Burnouf, Kuo-Hsiang Chuang, Chien-Hsiun Chen, Tian-Lu Cheng, Yuan-Tsong Chen, Jer-Yuarn Wu, Steve R Roffler
Polyethylene glycol (PEG) is a biocompatible polymer that is often attached to therapeutic molecules to improve bioavailability and therapeutic efficacy. Although antibodies with specificity for PEG may compromise the safety and effectiveness of PEGylated medicines, the prevalence of pre-existing anti-PEG antibodies in healthy individuals is unclear. Chimeric human anti-PEG antibody standards were created to accurately measure anti-PEG IgM and IgG antibodies by direct ELISA with confirmation by a competition assay in the plasma of 1504 healthy Han Chinese donors residing in Taiwan...
October 11, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27709238/body-composition-and-anti-neoplastic-treatment-in-adult-and-older-subjects-a-systematic-review
#15
S Gérard, D Bréchemier, A Lefort, S Lozano, G Abellan Van Kan, T Filleron, L Mourey, C Bernard-Marty, M E Rougé-Bugat, V Soler, B Vellas, M Cesari, Y Rolland, L Balardy
BACKGROUND: The estimation of the risk of poor tolerance and overdose of antineoplastic agents protocols represents a major challenge in oncology, particularly in older patients. We hypothesize that age-related modifications of body composition (i.e. increased fat mass and decreased lean mass) may significantly affect tolerance to chemotherapy. METHOD: We conducted a systematic review for the last 25 years (between 1990 and 2015), using US National library of Medicine Medline electronic bibliographic database and Embase database of cohorts or clinical trials exploring (i) the interactions of body composition (assessed by Dual X-ray Absorptiometry, Bioelectrical Impedance Analyses, or Computerized Tomography) with pharmacokinetics parameters, (ii) the tolerance to chemotherapy, and (iii) the consequences of chemotherapies or targeted therapies on body composition...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27692013/a-comparative-study-of-patient-characteristics-opinions-and-outcomes-for-patients-who-leave-the-emergency-department-before-medical-assessment
#16
Jacqueline Fraser, Paul Atkinson, Audra Gedmintas, Michael Howlett, Rose McCloskey, James French
OBJECTIVE: The emergency department (ED) left-without-being-seen (LWBS) rate is a performance indicator, although there is limited knowledge about why people leave, or whether they seek alternate care. We studied characteristics of ED LWBS patients to determine factors associated with LWBS. METHODS: We collected demographic data on LWBS patients at two urban hospitals. Sequential LWBS patients were contacted and surveyed using a standardized telephone survey. A matched group of patients who did not leave were also surveyed...
October 3, 2016: CJEM
https://www.readbyqxmd.com/read/27683916/highly-active-immunomodulatory-therapy-ameliorates-accumulation-of-disability-in-moderately-advanced-and-advanced-multiple-sclerosis
#17
Nathaniel Lizak, Alessandra Lugaresi, Raed Alroughani, Jeannette Lechner-Scott, Mark Slee, Eva Havrdova, Dana Horakova, Maria Trojano, Guillermo Izquierdo, Pierre Duquette, Marc Girard, Alexandre Prat, Pierre Grammond, Raymond Hupperts, Francois Grand'Maison, Patrizia Sola, Eugenio Pucci, Roberto Bergamaschi, Celia Oreja-Guevara, Vincent Van Pesch, Cristina Ramo, Daniele Spitaleri, Gerardo Iuliano, Cavit Boz, Franco Granella, Javier Olascoaga, Freek Verheul, Csilla Rozsa, Edgardo Cristiano, Shlomo Flechter, Suzanne Hodgkinson, Maria Pia Amato, Norma Deri, Vilija Jokubaitis, Tim Spelman, Helmut Butzkueven, Tomas Kalincik
OBJECTIVE: To evaluate variability and predictability of disability trajectories in moderately advanced and advanced multiple sclerosis (MS), and their modifiability with immunomodulatory therapy. METHODS: The epochs between Expanded Disability Status Scale (EDSS) steps 3-6, 4-6 and 6-6.5 were analysed. Patients with relapse-onset MS and having reached 6-month confirmed baseline EDSS step (3/4/6) were identified in MSBase, a global observational MS cohort study...
September 28, 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27633341/what-a-difference-a-day-makes-differences-in-initial-abstinence-response-during-a-smoking-cessation-attempt
#18
Megan E Piper, Sara A Vasilenko, Jessica W Cook, Stephanie T Lanza
AIMS: To (1) identify distinct classes of smokers based on quit day withdrawal symptoms and (2) explore the relations between withdrawal classes and demographics, tobacco dependence, treatment and smoking outcomes. DESIGN: Secondary data analysis of participants (n = 1504) in a randomized double-blind placebo-controlled multi-site smoking cessation trial who provided ecological momentary assessments of withdrawal symptoms on their quit day. Participants received smoking cessation counseling and were randomized to receive placebo or one of five active pharmacotherapies...
February 2017: Addiction
https://www.readbyqxmd.com/read/27591410/association-study-of-dopamine-receptor-genes-polymorphisms-with-the-risk-of-schizophrenia-in-the-han-chinese-population
#19
Beimeng Yang, Weibo Niu, Shiqing Chen, Fei Xu, Xingwang Li, Xi Wu, Yanfei Cao, Rui Zhang, Fengping Yang, Lu Wang, Weidong Li, Yifeng Xu, Lin He, Guang He
Schizophrenia is a highly heritable psychiatric disorder often associated with dopamine-related genetic variations. Thus, we performed a case-control study in 1504 Han Chinese population to evaluate the association of DRD1, DRD2 and DRD3 polymorphisms with schizophrenia. No statistically significant difference in allelic or genotypic frequency was found between schizophrenia and control subjects. Strong positive linkage disequilibrium was detected among the SNPs within DRD1 and DRD2. However, no positive haplotype distribution was found to be associated with schizophrenia...
November 30, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27573429/central-obesity-increases-risk-of-breast-cancer-irrespective-of-menopausal-and-hormonal-receptor-status-in-women-of-south-asian-ethnicity
#20
R Nagrani, S Mhatre, P Rajaraman, I Soerjomataram, P Boffetta, S Gupta, V Parmar, R Badwe, R Dikshit
BACKGROUND: Current evidence suggests that the relationship between obesity and breast cancer (BC) risk may vary between ethnic groups. METHODS: A total of 1633 BC cases and 1504 controls were enrolled in hospital-based case-control study in Mumbai, India, from 2009 to 2013. Along with detailed questionnaire, we collected anthropometric measurements on all participants. We used unconditional logistic regression models to estimate odds ratios (ORs) and 95% confidence interval (CI) for BC risk associated with anthropometry measurements, stratified on tumour subtype and menopausal status...
October 2016: European Journal of Cancer
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