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Debasis Banerjee, Xianyin Chen, Sergey Lobanov, Anna M Plonka, Xiaojun Chan, John Daly, Taejin Kim, Praveen K Thallapally, John Parise
Used nuclear fuel reprocessing represents a unique challenge when dealing with radionuclides such as isotopes of85 Kr and129 I2 due to their volatility and long half-life. Efficient capture of129 I2 (t1/2 = 15.7 ×106 million years) from the nuclear waste stream can help reduce the risk of releasing I2 radionuclide into the environment and/or potential incorporation into the human thyroid. Metal organic frameworks have the reported potential to be I2 adsorbents but the effect of water vapor, generally present in the reprocessing off-gas stream, is rarely taken into account...
March 16, 2018: ACS Applied Materials & Interfaces
Pradipta Kr Das
An analytical model for the electrophoretic speed of DNA translocating through nanopore functionalized with polyelectrolyte brush is developed for the first time. The electrophoretic speed depends on DNA surface potential, applied electric field, viscosity and permittivity of solution along with velocity and electrostatic potential at liquid/ polyelectrolyte layer interface where the interface seemed to behave similar to that of a solid state nanopore wall. Under the limit of Debye-Hückel linearization, the electrostatic potential at liquid/ polyelectrolyte layer interface and at DNA surface have been calculated...
March 15, 2018: Electrophoresis
Taraka Ramji Moturu, Sravan Kumar Thula, Ravi Kumar Singh, Tomasz Nodzynski, Radka Svobodová Vareková, Jirí Friml, Sibu Simon
Strigolactones (SLs) are relatively recent addition to plant hormones that reported to control different aspects of plant development. SL signalling is perceived by an α/β hydrolase DWARF 14 (D14). A close homologue of D14, KARRIKIN INSENSTIVE2 (KAI2) involved in perception of an uncharacterized molecule called Karrikin (KR). Recent studies identified the SUPPRESSOR OF MAX2 1 (SMAX1) and SMXL7 in Arabidopsis to be potential SCF-MAX2 complex mediated proteasome targets of KAI2 and D14 respectively. Genetic studies on SMXL7 and SMAX1 demonstrated distinct developmental roles of each but very little sequence features are known about these repressors...
March 10, 2018: Journal of Experimental Botany
Jin Soo Lee, Seong-Joon Lee, Ji Man Hong, Jin Wook Choi, Jeong-Ho Hong, Hyuk-Won Chang, Chang-Hyun Kim, Yong-Won Kim, Dong-Hun Kang, Yong-Sun Kim, Bruce Ovbiagele, Andrew M Demchuk, Yang-Ha Hwang, Sung-Il Sohn
Background and Purpose: The purpose of the current study is to evaluate the influence of temporal patterns related to the availability of new endovascular treatment (EVT) devices on care processes and outcomes among patients with AIS. Materials and Methods: We enrolled 720 consecutive patients (January 2011 to May 2016) in a retrospective registry, ASIAN KR, from three Korean hospitals, who received EVT for acute ischemic stroke (AIS) caused by cervicocephalic arterial occlusions...
March 2018: Neurointervention
Jinlong Du, Zaoming Wu, Engang Fu, Yanxiang Liang, Xingjun Wang, Peipei Wang, Kaiyuan Yu, Xiangdong Ding, Meimei Li, Marquis Kirk
The mechanism of radiation-induced detwinning is different from that of deformation detwinning as the former is dominated by supersaturated radiation-induced defects while the latter is usually triggered by global stress. In situ Kr ion irradiation was performed to study the detwinning mechanism of nanotwinned Cu films with various twin thicknesses. Two types of incoherent twin boundaries (ITBs), so-called fixed ITBs and free ITBs, are characterized based on their structural features, and the difference in their migration behavior is investigated...
2018: Science and Technology of Advanced Materials
Hyun-Kyung Do, Joong-Hoon Lee, Jae-Young Lim
OBJECTIVE: Polydeoxyribonucleotide as adenosine receptor (A2A ) agonist has been used in plastic surgery and dermatology related to its regenerative property. The aim of this pilot study is to evaluate the safety and efficacy of polydeoxynucleotide injection in patients with rotator cuff tears by a variety of outcomes including pain, disability, physical performance test, and ultrasonography (US). METHODS: Seventeen patients (9 men, 8 women, age: 57.9 ± 9.1) with partial-thickness tear of supraspinatus tendon were evaluated in a prospective, open-label, and pre-and-post study...
March 14, 2018: Physician and Sportsmedicine
Gian Mauro Manzoni, Alessandro Rossi, Giada Pietrabissa, Giorgia Varallo, Enrico Molinari, Eleonora Poggiogalle, Lorenzo Maria Donini, Giulietta Tarrini, Nazario Melchionda, Carla Piccione, Giovanni Gravina, Gianluigi Luxardi, Emilia Manzato, Romana Schumann, Marco Innamorati, Claudio Imperatori, Mariantonietta Fabbricatore, Gianluca Castelnuovo
PURPOSE: This study was aimed to examine the structural and construct validity of the Italian version of the Yale Food Addiction Scale in a multisite sample of postgraduate students. METHODS: Two hundred and fifty-six subjects (78.1% females) aged from 18 to 53 years (mean = 23.93, SD = 4.96) and attending different postgraduate university programs at multiple Italian universities completed the Italian YFAS, the Italian Binge Eating Scale (BES), the Italian Eating Attitudes Test-26 and the Italian Dutch Eating Behavior Questionnaire (DEBQ) online through Qualtrics...
March 12, 2018: Eating and Weight Disorders: EWD
Sang Woo Jun, Suk Joong Yong, Min Jo, Young Ho Kim, Sung Hoon Kim
BACKGROUND: Electromyography and the modified Ashworth scale (MAS) are among the most effective methods for evaluating spasticity; however, these are often inappropriate for clinical use, owing to the complicated procedure and subjective evaluation outcomes. METHODS: A passive stretch reflex test was performed on 10 subjects with brain lesions. Furthermore, mechanomyography and electromyography were conducted on the vastus lateralis muscle (agonist) and semitendinosus muscle (antagonist) of the subjects with brain lesions...
March 6, 2018: Clinical Biomechanics
Seiyed Mossa Hosseini, Tiziana Tosco, Behzad Ataie-Ashtiani, Craig T Simmons
Non-pumping reactive wells (NPRWs) filled by zero-valent iron (ZVI) can be utilized for the remediation of groundwater contamination of deep aquifers. The efficiency of NPRWs mainly depends on the hydraulic contact time (HCT) of the pollutant with the reactive materials, the extent of the well capture zone (Wcz ), and the relative hydraulic conductivity of aquifer and reactive material (Kr ). We investigated nitrate removal from groundwater using NPRWs filled by ZVI (in nano and micro scales) and examined the effect of NPRWs orientations (i...
February 27, 2018: Journal of Contaminant Hydrology
Zhongxia Shang, Jin Li, Cuncai Fan, Youxing Chen, Qiang Li, Tongde Shen, Haiyan Wang, Xinghang Zhang
Metallic materials subjected to heavy ion irradiation experience significant radiation damage. Free surface is a type of effective defect sinks to improve the radiation resistance in metallic materials. However, the radiation resistance of metallic nanowires is largely unknown. Here we show, via in situ Kr ion irradiations in a transmission electron microscope, Ag nanowires exhibited much better radiation resistance than coarse-grained Ag. Irradiation-induced prominent surface roughening in Ag nanowires provides direct evidence for interaction between defect clusters and free surface...
March 8, 2018: Nanotechnology
Linda Kievit, Pia Kræmer, Stephen Hamilton-Dutoit, Henning Grønbæk
A 37-year-old male, who at the age of 8 years had been treated for right-sided Wilms' tumor with nephrectomy, radiotherapy, and chemotherapy, presented with noncirrhotic portal hypertension (NCPH), grade 2 esophageal varices, and ascites. A CT scan demonstrated hypoplasia of liver segments 2 and 3. A liver biopsy showed portal tract fibrosis without cirrhosis, with histological features of NCPH. Liver vein catheterization showed a normal portal pressure gradient of 5 mm Hg while spleen to hepatic vein pressure was 29 mm Hg...
January 2018: Case Reports in Gastroenterology
Yoojoong Kim, Yeong Seon Kang, Junhee Seok
Motivation: Despite the potential usefulness, the association analysis of gene expression with interval times of two events has been hampered because the occurrence of events can be censored and the conventional survival analysis is not suitable to handle two censored events. However, the recent advances of multivariate survival analysis considering multiple censored events together provide an unprecedented chance for this problem. Based on such advances, we have developed a software tool, GAIT, for the association analysis of gene expression with interval time of two events...
March 2, 2018: Bioinformatics
GunHwan Ko, Pan-Gyu Kim, Jongcheol Yoon, Gukhee Han, Seong-Jin Park, Wangho Song, Byungwook Lee
BACKGROUND: While next-generation sequencing (NGS) costs have fallen in recent years, the cost and complexity of computation remain substantial obstacles to the use of NGS in bio-medical care and genomic research. The rapidly increasing amounts of data available from the new high-throughput methods have made data processing infeasible without automated pipelines. The integration of data and analytic resources into workflow systems provides a solution to the problem by simplifying the task of data analysis...
February 19, 2018: BMC Bioinformatics
Louise Prestipino, Jaimie W Polson, Elisabeth Brolin, Helen E Ritchie
A slow embryonic heart rate in early-mid gestation is associated with increased risk of embryonic death and malformation, however, the long-term consequences remain unknown. We administered Dofetilide (Dof, 2.5 mg/kg), a drug that produces embryo-specific bradycardia, to pregnant rats from gestational days 11-14. Embryonic heart rate and rhythm were determined using embryo culture. Cardiovascular function was assessed in surviving adult offspring at rest, during acute psychological stress (air jet stress, AJS), and after 7 days of repeated AJS...
March 2018: Physiological Reports
Bernhard Bereiter, Kenji Kawamura, Jeffrey P Severinghaus
RATIONALE: The global ocean constitutes the largest heat buffer in the global climate system, but little is known about its past changes. The isotopic and elemental ratios of heavy noble gases (krypton and xenon), together with argon and nitrogen in trapped air from ice cores can be used to reconstruct past mean ocean temperatures (MOTs). Here we introduce two successively developed methods to measure these parameters with a sufficient precision to provide new constraints on past MOT changes...
March 3, 2018: Rapid Communications in Mass Spectrometry: RCM
Majid Fereidoon, Manfred Koch
Agriculture is one of the environmental/economic sectors that may adversely be affected by climate change, especially, in already nowadays water-scarce regions, like the Middle East. One way to cope with future changes in absolute as well as seasonal (irrigation) water amounts can be the adaptation of the agricultural crop pattern in a region, i.e. by planting crops which still provide high yields and so economic benefits to farmers under such varying climate conditions. To do this properly, the whole cascade starting from climate change, effects on hydrology and surface water availability, subsequent effects on crop yield, agricultural areas available, and, finally, economic value of a multi-crop cultivation pattern must be known...
February 24, 2018: Science of the Total Environment
Hyun-Chul Park, Eu-Ree Ahn, Ju Yeon Jung, Ji-Hye Park, Jee Won Lee, Si-Keun Lim, Won Kim
DNA methylation has important biological roles, such as gene expression regulation, as well as practical applications in forensics, such as in body fluid identification and age estimation. DNA methylation often occurs in the CpG site, and methylation within the CpG islands affects various cellular functions and is related to tissue-specific identification. Several programs have been developed to identify CpG islands; however, the size, location, and number of predicted CpG islands are not identical due to different search algorithms...
February 17, 2018: Forensic Science International. Genetics
Igor Baburin, Rosanne Varkevisser, Anja Schramm, Priyanka Saxena, Stanislav Beyl, Phillip Szkokan, Tobias Linder, Anna Stary-Weinzinger, Marcel A G van der Heyden, Marien Houtman, Hiroki Takanari, Malin Jonsson, Jet H D Beekman, Matthias Hamburger, Marc A Vos, Steffen Hering
Evodiae fructus is a widely used herbal drug in traditional Chinese medicine. Evodia extract was found to inhibit hERG channels. The aim of the current study was to identify hERG inhibitors in Evodia extract and to investigate their potential proarrhythmic effects. Dehydroevodiamine (DHE) and hortiamine were identified as IKr (rapid delayed rectifier current) inhibitors in Evodia extract by HPLC-microfractionation and subsequent patch clamp studies on human embryonic kidney cells. DHE and hortiamine inhibited IKr with IC50 s of 253...
February 22, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
Ivón Oramas Polo, Linda V E Caldas
In beta emitters, in order to evaluate the absorbed dose rate at different tissue depths, it is necessary to determine the transmission factors. In this work, the transmission factors determined in beta secondary standard radiation beams are presented. For this purpose, an extrapolation chamber was used. The results obtained were considered acceptable, and they are within the uncertainties in comparison with the values provided by the source calibration certificate. The maximum differences between the results obtained in this work and those from the calibration certificate were 3...
February 9, 2018: Applied Radiation and Isotopes
I P Munugoda, K Wills, F Cicuttini, S E Graves, M Lorimer, G Jones, M L Callisaya, D Aitken
OBJECTIVE: To examine the association between ambulatory activity (AA), body composition measures and hip or knee joint replacement (JR) due to osteoarthritis. DESIGN: At baseline, 1082 community-dwelling older-adults aged 50 - 80 years were studied. AA was measured objectively using pedometer and body composition by dual-energy x-ray absorptiometry. The incidence of primary (first-time) JR was determined by data linkage to the Australian Orthopaedic Association National Joint Replacement Registry...
February 20, 2018: Osteoarthritis and Cartilage
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