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Intravascular optical coherence tomography

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https://www.readbyqxmd.com/read/28077820/acute-coronary-syndrome-demonstrating-plaque-rupture-in-calcified-lesions-visualized-by-optical-frequency-domain-imaging
#1
Yutaka Goryo, Teruyoshi Kume, Yusuke Kobayashi, Hiroshi Okamoto, Ai Kawamura, Kenzo Fukuhara, Terumasa Koyama, Ryotaro Yamada, Koichiro Imai, Yoji Neishi, Shiro Uemura
A 68-year-old female with acute coronary syndrome was transferred to our hospital. Emergency coronary angiography showed 90% stenosis with severe calcification in the proximal right coronary artery (RCA). Intravascular ultrasound (IVUS) images were obtained and showed circumferential heavy calcification without any evidence of plaque rupture. Optical frequency domain imaging (OFDI) images were obtained in the RCA lesion 3 days after the initial coronary angiography. A cavity of plaque rupture in the calcified plaque by using OFDI was observed in the lesion, which could not be recognized by IVUS...
January 11, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28069611/bioresorbable-vascular-scaffolds-for-the-treatment-of-chronic-total-occlusions-an-international-multicenter-registry
#2
Satoru Mitomo, Toru Naganuma, Yusuke Fujino, Hiroyoshi Kawamoto, Sandeep Basavarajaiah, Michael Pitt, Wei-Hsian Yin, Damras Tresukosol, Antonio Colombo, Sunao Nakamura
BACKGROUND: There are only limited studies reporting clinical outcomes after bioresorbable vascular scaffold (BVS; Absorb; Abbott Vascular, Santa Clara, CA) implantation for coronary chronic total occlusions (CTO). The aim of this study was to evaluate the real-world feasibility and safety of BVS implantation for the treatment of CTO. METHODS AND RESULTS: We retrospectively evaluated CTO cases treated with BVS from a multicenter registry. The primary end point was target lesion failure defined as a composite of cardiac death, target vessel myocardial infarction, and clinically driven target lesion revascularization...
January 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28064551/fd-oct-and-ivus-intravascular-imaging-modalities-in-peripheral-vasculature
#3
S Spiliopoulos, P Kitrou, K Katsanos, D Karnabatidis
Intra-Vascular Ultra-Sound (IVUS) and Frequency Domain-Optical Coherence Tomography (FD-OCT), in vivo, intra-vascular, imaging modalities, widely used in the field of coronary disease, have been recently implemented in peripheral endovascular procedures, for procedural assessment, plaque characterization and determination of predictors of treatment outcomes. Their unique characteristics have also been used in order to provide additional features and improve the performance of re-entry devices and atherotomes...
January 13, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28059849/is-age-an-important-factor-for-vascular-response-to-statin-therapy-a-serial-optical-coherence-tomography-and-intravascular-ultrasound-study
#4
Jiannan Dai, Jingbo Hou, Lei Xing, Haibo Jia, Sining Hu, Tsunenari Soeda, Yoshiyasu Minami, Daniel Ong, Rocco Vergallo, Shaosong Zhang, Hang Lee, Bo Yu, Ik-Kyung Jang
OBJECTIVE: Age-related structural and functional changes in vessel wall may affect the time course of vascular response to statin therapy. In this study, we sought to compare the response of lipid-rich plaque to statin therapy in elderly versus younger patients using optical coherence tomography and intravascular ultrasound. PATIENTS AND METHODS: Sixty-nine patients who underwent serial optical coherence tomography and intravascular ultrasound at the time point of baseline, 6, and 12 months were divided into two groups according to median age: group A (age<57 years, n=35) and group B (age≥57 years, n=34)...
January 4, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28012553/comparison-of-percutaneous-coronary-intervention-versus-coronary-artery-bypass-grafting-for-unprotected-left-main-coronary-artery-disease
#5
REVIEW
Syed Yaseen Naqvi, Jordan Klein, Tisa Saha, Daniel J McCormick, Sheldon Goldberg
Coronary artery bypass grafting (CABG) decreases mortality in patients with significant left main (LM) coronary artery disease and for years remained the therapy of choice for patients with this ominous lesion. Advances in percutaneous coronary intervention (PCI) have enabled it to become an alternative to CABG. The results of observational registries and randomized comparisons have shown the safety and efficacy of PCI in appropriately selected patients with low or intermediate angiographic risk scores. Furthermore, the use of physiological measures of flow limitation and the use of intracoronary imaging techniques has added benefit and improved outcomes...
November 16, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27998841/automated-characterisation-of-lipid-core-plaques-in-vivo-by-quantitative-optical-coherence-tomography-tissue-type-imaging
#6
Muthukaruppan Gnanadesigan, Takeyoshi Kameyama, Antonios Karanasos, Nienke S van Ditzhuijzen, Johannes N van der Sijde, Robert-Jan van Geuns, Jurgen Ligthart, Karen Witberg, Giovanni J Ughi, Antonius F van der Steen, Evelyn Regar, Gijs van Soest
AIMS: Qualitative criteria for plaque tissue characterisation by OCT are well established, but quantitative methods lack systematic validation in vivo. High optical attenuation coefficient µt has been associated with unstable plaque features, such as lipid core. The purpose of this study was to validate optical coherence tomography (OCT) attenuation imaging for tissue characterisation in vivo, specifically to detect lipid core in coronary atherosclerotic plaques, and to evaluate quantitatively the ability of OCT attenuation imaging to differentiate thin-cap (TCFA) and thick-cap fibroatheroma (FA)...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27998840/quantification-and-characterisation-of-released-plaque-material-during-bioresorbable-vascular-scaffold-implantation-into-right-coronary-artery-lesions-by-multimodality-intracoronary-imaging
#7
Heike A Hildebrandt, Polykarpos C Patsalis, Fadi Al-Rashid, Markus Neuhäuser, Tienush Rassaf, Gerd Heusch, Philipp Kahlert, Petra Kleinbongard
AIMS: We aimed to compare intravascular ultrasound with virtual histology (VH-IVUS), optical coherence tomography (OCT) and near-infrared spectroscopy (NIRS) for their ability to quantify the true amount and characterise the nature of released plaque material during bioresorbable vascular scaffold (BVS) implantation into right coronary artery (RCA) lesions using a distal occlusion and aspiration device. METHODS AND RESULTS: Seventeen patients underwent BVS implantation into the right coronary artery under distal protection with intracoronary imaging using VH-IVUS, OCT and NIRS...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27993755/clinical-angiographic-ivus-and-oct-predictors-for-irregular-protrusion-after-coronary-stenting
#8
Krzysztof L Bryniarski, Seung-Jea Tahk, So-Yeon Choi, Tsunenari Soeda, Takumi Higuma, Erika Yamamoto, Lei Xing, Jiannan Dai, Thomas Zanchin, Hang Lee, Ik-Kyung Jang
AIMS: Irregular protrusion identified by optical coherence tomography (OCT) immediately following stent implantation has been reported as an independent predictor for adverse cardiac events at 1 year. However, baseline characteristics for development of irregular protrusion are unknown. The aim of the study was to identify predictors for irregular protrusion following stent implantation. METHODS AND RESULTS: A total of 900 lesions in 786 patients who had post-stent OCT imaging were analyzed...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27992371/relation-between-baseline-plaque-features-and-subsequent-coronary-artery-remodeling-determined-by-optical-coherence-tomography-and-intravascular-ultrasound
#9
Zulong Xie, Nana Dong, Rong Sun, Xinxin Liu, Xia Gu, Yong Sun, Hongwei Du, Jiannan Dai, Youbin Liu, Jingbo Hou, Jinwei Tian, Bo Yu
Atherosclerosis often leads to myocardial infarction and stroke. We examined the influence of baseline plaque characteristics on subsequent vascular remodeling in response to changes in plaque size. Using optical coherence tomography (OCT) and intravascular ultrasound (IVUS), we examined 213 plaques from 138 patients with acute coronary syndrome at baseline and repeated IVUS at the 12-month follow-up. The change in external elastic membrane (EEM) area for each 1 mm2 change in plaque area (i.e., the slope of the regression line) was calculated as a measure of vascular remodeling capacity...
December 15, 2016: Oncotarget
https://www.readbyqxmd.com/read/27989887/assessment-of-fibrous-cap-thickness-by-optical-coherence-tomography-in-vivo-reproducibility-and-standardization
#10
Annapoorna S Kini, Yuliya Vengrenyuk, Takahiro Yoshimura, Mitsuaki Matsumura, Jacobo Pena, Usman Baber, Pedro Moreno, Roxana Mehran, Akiko Maehara, Samin Sharma, Jagat Narula
BACKGROUND: OCT imaging is considered to be the only imaging modality which has resolution sufficient to measure fibrous cap thickness (FCT) in vivo. However, reproducibility of the measurements in vivo has been unsatisfactory. OBJECTIVES: The purpose of this study was to investigate whether a satisfactory reproducibility of FCT measurements by OCT in vivo can be achieved between independent observers. METHODS: One hundred seventy OCT pullbacks were analyzed by two independent observers with intravascular imaging expertise according to the current guidelines to assess the interobserver variability of FCT measurement by intraclass correlation coefficient (ICC)...
October 27, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27989886/intracoronary-imaging-cholesterol-efflux-and-transcriptomes-after-intensive-statin-treatment-the-yellow-ii-study
#11
Annapoorna S Kini, Yuliya Vengrenyuk, Khader Shameer, Akiko Maehara, Meerarani Purushothaman, Takahiro Yoshimura, Mitsuaki Matsumura, Melissa Aquino, Nezam Haider, Kipp W Johnson, Ben Readhead, Brian A Kidd, Jonathan E Feig, Prakash Krishnan, Joseph Sweeny, Milind Mahajan, Pedro Moreno, Roxana Mehran, Jason C Kovacic, Usman Baber, Joel T Dudley, Jagat Narula, Samin Sharma
BACKGROUND: Despite the extensive evidence for the beneficial effects of statins on clinical outcomes, the mechanisms underlying these effects in remain elusive. OBJECTIVES: To assess the changes in plaque morphology by intravascular imaging with a comprehensive evaluation of cholesterol efflux capacity (CEC) and peripheral blood mononuclear cells (PBMC) transcriptomics in patients receiving high-dose statin therapy. METHODS: In a prospective study, 85 patients with stable multivessel coronary artery disease underwent percutaneous coronary intervention for a culprit lesion followed by intracoronary multi-modality imaging including optical coherence tomography (OCT) of an obstructive non-culprit lesion (NCL)...
October 27, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27987040/lipid-lowering-therapy-stabilizes-the-complexity-of-non-culprit-plaques-in-human-coronary-artery-a-quantitative-assessment-using-oct-bright-spot-algorithm
#12
Yoshiyasu Minami, Taylor Hoyt, Jennifer E Phipps, Thomas E Milner, Lei Xing, Hang Lee, Bo Yu, Marc D Feldman, Ik-Kyung Jang
To quantitatively evaluate the change of plaque complexity with cholesterol lowering therapy. A total of 44 non-culprit plaques from 30 patients who had serial image acquisition at baseline, 6-months, and 12-months by both optical coherence tomography (OCT) and intravascular ultrasound (IVUS) were included. Patients were treated with atorvastatin 60 mg (AT60, n = 16) or 20 mg (AT20, n = 14). We applied an OCT bright spot algorithm, which identifies a variety of plaque components including macrophages...
December 16, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27983695/validating-intravascular-imaging-with-serial-optical-coherence-tomography-and-confocal-fluorescence-microscopy
#13
Pier-Luc Tardif, Marie-Jeanne Bertrand, Maxime Abran, Alexandre Castonguay, Joël Lefebvre, Barbara E Stähli, Nolwenn Merlet, Teodora Mihalache-Avram, Pascale Geoffroy, Mélanie Mecteau, David Busseuil, Feng Ni, Abedelnasser Abulrob, Éric Rhéaume, Philippe L'Allier, Jean-Claude Tardif, Frédéric Lesage
Atherosclerotic cardiovascular diseases are characterized by the formation of a plaque in the arterial wall. Intravascular ultrasound (IVUS) provides high-resolution images allowing delineation of atherosclerotic plaques. When combined with near infrared fluorescence (NIRF), the plaque can also be studied at a molecular level with a large variety of biomarkers. In this work, we present a system enabling automated volumetric histology imaging of excised aortas that can spatially correlate results with combined IVUS/NIRF imaging of lipid-rich atheroma in cholesterol-fed rabbits...
December 15, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27981064/automatic-segmentation-of-coronary-morphology-using-transmittance-based-lumen-intensity-enhanced-intravascular-optical-coherence-tomography-images-and-applying-a-localized-level-set-based-active-contour-method
#14
Shiju Joseph, Asif Adnan, David Adlam
Lumen segmentation from clinical intravascular optical coherence tomography (IV-OCT) images has clinical relevance as it provides a full three-dimensional perspective of diseased coronary artery sections. Inaccurate segmentation may occur when there are artifacts in the image, resulting from issues such as inadequate blood clearance. This study proposes a transmittance-based lumen intensity enhancement method that ensures only lumen regions are highlighted. A level-set-based active contour method that utilizes the local speckle distribution properties of the image is then employed to drive an image-specific active contour toward the true lumen boundaries...
October 2016: Journal of Medical Imaging
https://www.readbyqxmd.com/read/27970125/tct-73-serial-three-vessel-optical-coherence-tomography-and-intravascular-ultrasound-analysis-of-changing-morphologies-associated-of-plaque-progression-in-patients-with-stable-angina-pectoris
#15
Myong Hwa Yamamoto, Kennosuke Yamashita, Mitsuaki Matsumura, Seitarou Ebara, Toshitaka Okabe, Shigeo Saito, Koichi Hoshimoto, Kisaki Amemiya, Tadayuki Yakushiji, Naoei Isomura, Hiroshi Araki, Chiaki Obara, Masahiko Ochiai, Gary Mintz, Akiko Maehara
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969966/tct-591-optical-coherence-tomography-guided-pci-does-not-lead-to-an-increase-in-contrast-use-compared-to-intravascular-ultrasound-guided-pci
#16
David Lee, Matteo Bianco, Paul Johnson, Prashant Kaul
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969940/tct-570-histology-validated-neural-networks-enable-plaque-tissue-and-thin-capped-fibroatheroma-characterization-through-intravascular-optical-coherence-tomography-based-virtual-histology
#17
Vikram Baruah, Aydin Zahedivash, Hoyt Taylor, Austin McElroy, Deborah Vela, L Maximilian Buja, Thomas Milner, Marc Feldman
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969934/tct-566-association-between-lesion-remodeling-and-plaque-morphology-assessed-by-intravascular-ultrasound-and-optical-coherence-tomography
#18
Mitsuaki Matsumura, Gary Mintz, Wenbin Zhang, Yang Cao, Cheolmin Lee, Tsunekazu Kakuta, Akiko Maehara
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969921/tct-552-serial-assessment-of-calcification-5-years-after-bioresorbable-vascular-scaffold-implantation-fusion-of-intravascular-ultrasound-and-optical-coherence-tomography
#19
Yaping Zeng, Hiroki Tateishi, Rafael Cavalcante, Erhan Tenekecioglu, Pannipa Suwannasom, Yohei Sotomi, Carlos Collet, Shao-Ping Nie, Hans Jonker, Jouke Dijkstra, Maria Radu, Lorenz Raber, Dougal Mcclean, Robert-Jan van Geuns, Evald Christiansen, Fahrni Therese, Jacques Koolen, Yoshinobu Onuma, Patrick Serruys
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969756/tct-405-optical-coherence-tomography-guided-optimal-bioresorbable-vascular-scaffold-implantation-informs-subsequent-implantation-without-intravascular-imaging-further-evidence-for-a-learning-curve
#20
Vincent Floré, Adam Brown, James Cranley, Joel Giblett, Stephen Hoole, Nick West
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
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