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Intravascular optical coherence tomography

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https://www.readbyqxmd.com/read/29135482/long-term-darapladib-use-does-not-affect-coronary-plaque-composition-assessed-using-multimodality-intravascular-imaging-modalities-a-randomized-controlled-study
#1
Woong Gil Choi, Megha Prasad, Ryan Lennon, Rajiv Gulati, Abhiram Prasad, Lilach O Lerman, Amir Lerman
BACKGROUND: Lipoprotein-associated phospholipase A2 (Lp-PLA2) may play a role in plaque progression and vulnerability. We aimed to define plaque characteristics on multimodality intravascular imaging in patients with coronary endothelial dysfunction in response to long-term inhibition of Lp-PLA2 by darapladib. PATIENTS AND METHODS: This is a double-blinded, randomized study screening 70 patients, and enrolling 54 patients with suspected ischemia, without obstructive disease on angiography and with coronary endothelial dysfunction by invasive assessment...
November 10, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29133478/clinical-relevance-of-18-f-sodium-fluoride-positron-emission-tomography-in-noninvasive-identification-of-high-risk-plaque-in-patients-with-coronary-artery-disease
#2
Joo Myung Lee, Ji-In Bang, Bon-Kwon Koo, Doyeon Hwang, Jonghanne Park, Jinlong Zhang, Tong Yaliang, Minseok Suh, Jin Chul Paeng, Yasutsugu Shiono, Takashi Kubo, Takashi Akasaka
BACKGROUND: (18)F-sodium fluoride ((18)F-NaF) positron-emission tomography has been introduced as a potential noninvasive imaging tool to identify plaques with high-risk characteristics in patients with coronary artery disease. We sought to evaluate the clinical relevance of (18)F-NaF uptake using optical coherence tomography (OCT), intravascular ultrasound (IVUS), and coronary computed tomography angiography in patients with coronary artery disease. METHODS AND RESULTS: The target population consisted of 51 prospectively enrolled patients (93 stenoses) who underwent (18)F-NaF positron-emission tomography before invasive coronary angiography...
November 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29127197/communicating-malapposition-of-flow-diverters-assessed-with-optical-coherence-tomography-correlates-with-delayed-aneurysm-occlusion
#3
Robert M King, Olivia W Brooks, Erin T Langan, Jildaz Caroff, Frédéric Clarençon, Takamitsu Tamura, John Michael Wainwright, Matthew J Gounis, Miklós Marosfői, Ajit S Puri
BACKGROUND: Optical coherence tomography (OCT) is a high resolution intravascular imaging method that allows visualization of flow diverter struts and the vessel wall. In this study, malapposition of the flow diverter that continues into the neck of the aneurysm, named communicating malapposition (CM), was investigated as a potential factor for delayed aneurysm healing. METHODS: 40 New Zealand White rabbits underwent elastase induced aneurysm creation, and were subsequently assigned to one of four treatment groups based on flow diverter type and administration of antiplatelet therapy...
November 10, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29109462/intravascular-optical-coherence-tomography-for-characterization-of-atherosclerosis-with-a-1-7-micron-swept-source-laser
#4
Yan Li, Joseph Jing, Emon Heidari, Jiang Zhu, Yueqiao Qu, Zhongping Chen
The main cause of acute coronary events, such as thrombosis, is the rupture of atherosclerotic plaques. Typical intravascular optical coherence tomography (IVOCT) imaging systems that utilize a 1.3 μm swept source laser are often used for identifying fibrous cap thickness of plaques, yet cannot provide adequate depth penetration to resolve the size of the lipid pool. Here, we present a novel  IVOCT system with a 1.7 μm center wavelength swept light source that can readily penetrate deeper into the tissue because of the longer wavelength and allows for better identification of plaques due to the lipid absorption spectrum at 1...
November 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29108400/early-experience-and-favorable-clinical-outcomes-of-everolimus-eluting-bioresorbable-scaffolds-for-coronary-artery-disease-in-korea
#5
Osung Kwon, Jung-Min Ahn, Do-Yoon Kang, Se Hun Kang, Pil Hyung Lee, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park, Duk-Woo Park, Seung-Jung Park
Background/Aims: Compared with metallic drug-eluting stents (DES), bioresorbable vascular scaffolds (BVS) may further improve long-term outcomes of percutaneous coronary intervention (PCI) in patients with coronary artery disease. We report our early experience with BVS in Korea. Methods: We evaluated 105 consecutive patients with BVS implanted at Asan Medical Center, Korea between October 21, 2015 and June 3, 2016. Angiographic results, and in-hospital and 6-month clinical outcomes were assessed...
November 7, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29099668/successful-conservative-treatment-of-massive-choroidal-relapse-in-2-retinoblastoma-patients-monitored-by-ultrasound-biomicroscopy-and-or-spectral-domain-optic-coherence-tomography
#6
Christina Stathopoulos, Marie-Claire Gaillard, Francesco Puccinelli, Philippe Maeder, Doris Hadjistilianou, Maja Beck-Popovic, Francis L Munier
PURPOSE: To report the occurrence and management of secondary choroidal infiltration in two retinoblastoma (rb) patients. METHODS: Fundus examination and imaging with spectral domain optical coherence tomography (SD-OCT), B-scan ultrasonography (B-scan), and ultrasound biomicroscopy (UBM). RESULTS: Case 1: A 19-month-old girl with multifocal unilateral group B rb pretreated with intravenous chemotherapy (IVC) was referred for further management...
November 3, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29066339/long-term-invasive-follow-up-of-bioresorbable-vascular-scaffold-optical-coherence-tomography-assessment-of-jailed-side-branches
#7
Valeria Paradies, Pieter C Smits, Georgios J Vachojannis, Kees-Jan Royaards, Jochem Wassing, Martin van der Ent
BACKGROUND: Little is known about the long term development of the tissue bridges covering the struts of bioresorbable vascular scaffold (BVS) at the side branches (SB) ostium. This study aims at assessing the resorption process of jailed SB after BVS implantation. METHODS: We performed both Optical Coherence Tomography (OCT) and Intravascular Ultrasound (IVUS) analysis of 7 patients enrolled in the ABSORB Cohort B trial at our center. Orifice SB area and mean thickness of tissue bridge covering SB were calculated from 2D assessment...
September 10, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29066157/relationship-between-optical-coherence-tomography-defined-in-stent-neoatherosclerosis-and-out-stent-arterial-remodeling-assessed-by-serial-intravascular-ultrasound-examinations-in-late-and-very-late-drug-eluting-stent-failure
#8
Makoto Araki, Taishi Yonetsu, Tetsumin Lee, Tadashi Murai, Yoshihisa Kanaji, Eisuke Usui, Junji Matsuda, Masahiro Hoshino, Takayuki Niida, Masahiro Hada, Sadamitsu Ichijo, Rikuta Hamaya, Yoshinori Kanno, Mitsuaki Isobe, Tsunekazu Kakuta
BACKGROUND: Little is known regarding the association between chronological out-stent vessel remodeling and in-stent tissue characteristics of drug-eluting stent (DES) failure. We aimed to evaluate the relationship between serial vessel remodeling after DES implantation and neoatherosclerosis (NA) assessed by optical coherence tomography (OCT) in patients with DES failure. METHODS: Forty-eight patients with late and very late stent failure after DES implantation, who underwent intravascular ultrasound (IVUS) at both the initial percutaneous coronary intervention and the time of stent failure and OCT imaging at the time of stent failure, were retrospectively investigated...
October 21, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/29060945/art-care-a-multi-modality-coronary-3d-reconstruction-and-hemodynamic-status-assessment-software
#9
Panagiotis K Siogkas, Kostas A Stefanou, Lambros S Athanasiou, Michail I Papafaklis, Lampros K Michalis, Dimitrios I Fotiadis
BACKGROUND: Due to the incremental increase of clinical interest in the development of software that allows the 3-dimensional (3D) reconstruction and the functional assessment of the coronary vasculature, several software packages have been developed and are available today. OBJECTIVE: Taking this into consideration, we have developed an innovative suite of software modules that perform 3D reconstruction of coronary arterial segments using different coronary imaging modalities such as IntraVascular UltraSound (IVUS) and invasive coronary angiography images (ICA), Optical Coherence Tomography (OCT) and ICA images, or plain ICA images and can safely and accurately assess the hemodynamic status of the artery of interest...
October 13, 2017: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29060164/fibroatheroma-identification-in-intravascular-optical-coherence-tomography-images-using-deep-features
#10
Mengdi Xu, Jun Cheng, Annan Li, Jimmy Addison Lee, Damon Wing Kee Wong, Akira Taruya, Atsushi Tanaka, Nicolas Foin, Philip Wong
Identifying vulnerable plaque is important in coronary heart disease diagnosis. Recent emerged imaging modality, Intravascular Optical Coherence Tomography (IVOCT), has been proved to be able to characterize the appearance of vulnerable plaques. Comparing with the manual method, automated fibroatheroma identification would be more efficient and objective. Deep convolutional neural networks have been adopted in many medical image analysis tasks. In this paper, we introduce deep features to resolve fibroatheroma identification problem...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059332/an-fsi-modeling-approach-to-combine-ivus-and-oct-for-more-accurate-patient-specific-coronary-cap-thickness-and-stress-strain-calculations
#11
Xiaoya Guo, Don P Giddens, David Molony, Chun Yang, Habib Samady, Jie Zheng, Gary Mintz, Akiko Maehara, Liang Wang, Xuan Pei, Zhi-Yong Li, Dalin Tang
Accurate cap thickness and stress/strain quantifications are of fundamental importance for vulnerable plaque research. Virtual histology intravascular ultrasound (VH-IVUS) sets cap thickness to zero when cap is under resolution limit and IVUS does not see it. An innovative modeling approach combining IVUS and optical coherence tomography (OCT) is introduced for cap thickness quantification and more accurate cap stress/strain calculations. In vivo IVUS and OCT coronary plaque data were acquired with informed consent obtained...
October 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29050684/comparison-of-accuracy-of-one-use-methods-for-calculating-fractional-flow-reserve-by-intravascular-optical-coherence-tomography-to-that-determined-by-the-pressure-wire-method
#12
Sun-Joo Jang, Jung-Min Ahn, Boyoung Kim, Ji-Min Gu, Hyung Jin Sung, Seung-Jung Park, Wang-Yuhl Oh
Although the identification of the hemodynamic significance of coronary lesions becomes important for revascularization strategy, the potential role of 3-dimensional high-resolution intracoronary optical coherence tomography (OCT) for predicting functional significance of coronary lesions remains unclear. We assessed the diagnostic performance of 2 computational approaches for deriving fractional flow reserve (FFR) from intravascular OCT images. We developed 2 methods to derive FFR-OCT by AFD (FFR-OCTAFD) and FFR-OCT by CFD (FFR-OCTCFD)...
September 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29044926/optical-coherence-tomography-guided-carotid-artery-stent-procedure-technique-and-potential-applications
#13
Suhail Dohad, Alexander Zhu, Sandeep Krishnan, Frances Wang, Serena Wang, Justin Cox, Timothy D Henry
OBJECTIVES: To (1) present a guide on how to perform optical coherence tomography (OCT) in carotid artery stenting (CAS), to (2) highlight several instructive cases illustrating OCT-guidance as an interventional strategy, and to (3) present the largest case-series of OCT-guided CAS performed in North America, demonstrating its feasibility as an imaging modality in this setting. BACKGROUND: OCT is an intravascular imaging method that captures images with an axial resolution 10 times higher than intravascular ultrasound...
October 16, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29036125/automatic-classification-of-atherosclerotic-tissue-in-intravascular-optical-coherence-tomography-images
#14
Ping Zhou, Tongjing Zhu, Chunliu He, Zhiyong Li
Intravascular optical coherence tomography (IVOCT) has been successfully utilized for in vivo diagnostics of coronary plaques. However, classification of atherosclerotic tissues is mainly performed manually by experienced experts, which is time-consuming and subjective. To overcome these limitations, an automatic method of segmentation and classification of IVOCT images is developed in this paper. The method is capable of detecting the plaque contour between the fibrous tissues and other components. Subsequently, the method classifies the tissues based on their texture features described by Fourier transform and discrete wavelet transform...
July 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29032714/fusion-of-optical-coherence-tomography-and-angiography-for-numerical-simulation-of-hemodynamics-in-bioresorbable-stented-coronary-artery-based-on-patient-specific-model
#15
Chenxi Huang, Yuanhang Zhou, Xiaoxin Mao, Jianhua Tong, Lei Zhang, Fei Chen, Yongtao Hao
Three-dimensional simulations of coronary artery using finite element analysis are considered as effective means to understand the biomechanical properties after the stent was deployed. Bioresorbable vascular scaffolds are new-generation stents used by people. Intravascular optical coherence tomography is an emerging technique for detecting struts. The common 3 D reconstruction methods are using Intravascular Ultrasound (IVUS) or angiographies. However, it loses the details about geometry model. Fusing of optical coherence tomography and angiography to reconstruct the bioresorbable stented coronary artery based on patient-specific mode is an innovative method to reconstruct the high fidelity geometry...
October 16, 2017: Computer Assisted Surgery (Abingdon, England)
https://www.readbyqxmd.com/read/29020287/optical-coherence-tomography-or-intravascular-ultrasound-to-optimize-coronary-stent-implantation
#16
Fernando Alfonso, Francesco Prati
No abstract text is available yet for this article.
November 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29016632/radial-artery-neointimal-hyperplasia-after-transradial-pci-serial-optical-coherence-tomography-volumetric-study
#17
Petr Kala, Jan Kanovsky, Tereza Novakova, Roman Miklik, Otakar Bocek, Martin Poloczek, Petr Jerabek, Lenka Prymkova, Tomas Ondrus, Jiri Jarkovsky, Milan Blaha, Gary S Mintz
AIMS: Transradial catheterization (TRC) is a dominant access site for coronary catheterization and percutaneous coronary interventions (PCI) in many centers. Previous studies reported higher intimal thickness of the radial artery (RA) wall in patients with a previous history of TRC. In this investigation the aim was to assess the intimal changes of RA using the optical coherence tomography (OCT) intravascular imaging in a serial manner. METHODS AND RESULTS: 100 patients with the diagnosis of non-ST-elevation myocardial infarction (nSTEMI) treated by PCI were enrolled (6 patients were excluded from this analysis because of occluded RA at follow-up [2 patients] and insufficient quality of OCT images [4 patients])...
2017: PloS One
https://www.readbyqxmd.com/read/28979905/the-role-of-intracoronary-imaging-in-acute-coronary-syndromes-oct-in-focus
#18
REVIEW
Ahmad Samir, Ahmed ElGuindy
Optical coherence tomography (OCT) has emerged as a powerful intravascular imaging modality in recent years. The introduction of frequency-domain OCT has simplified the procedure and enabled its safe utilisation in different clinical settings including acute coronary syndromes, where it can determine the mechanism of plaque disruption, thrombus burden, and guide percutaneous coronary intervention. In patients presenting with stent failure (stent thrombosis and instent restenosis), OCT can also be very useful in determining the underlying mechanism and guiding therapy thereafter...
December 30, 2016: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/28947003/arcoct-automatic-detection-of-lumen-border-in-intravascular-oct-images
#19
Grigorios-Aris Cheimariotis, Yiannis S Chatzizisis, Vassilis G Koutkias, Konstantinos Toutouzas, Andreas Giannopoulos, Maria Riga, Ioanna Chouvarda, Antonios P Antoniadis, Charalambos Doulaverakis, Ioannis Tsamboulatidis, Ioannis Kompatsiaris, George D Giannoglou, Nicos Maglaveras
BACKGROUND AND OBJECTIVE: Intravascular optical coherence tomography (OCT) is an invaluable tool for the detection of pathological features on the arterial wall and the investigation of post-stenting complications. Computational lumen border detection in OCT images is highly advantageous, since it may support rapid morphometric analysis. However, automatic detection is very challenging, since OCT images typically include various artifacts that impact image clarity, including features such as side branches and intraluminal blood presence...
November 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28939583/a-comparison-between-the-new-low-profile-visualized-intraluminal-support-lvis-blue-stent-and-the-flow-redirection-endoluminal-device-fred-in-bench-top-and-cadaver-studies
#20
Yoshikazu Matsuda, Joonho Chung, Kiffon Keigher, Demetrius Lopes
OBJECT: The aim of this study is to demonstrate the differences between the new Low-profile Visualized Intraluminal Support (LVIS Blue) stenting device and the Flow Redirection Endoluminal Device (FRED) using a series of bench-top evaluations and optical coherence tomography (OCT) images in a cadaveric preparation of the basilar artery. METHODS: The first part of the evaluation was bench-top microscopic documentation of metal coverage for LVIS Blue and FRED stents...
September 22, 2017: Journal of Neurointerventional Surgery
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