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https://www.readbyqxmd.com/read/29127535/predictors-of-hiv-testing-and-their-influence-on-prep-acceptance-in-men-who-have-sex-with-men-a-cross-sectional-study
#1
Tsz Ho Kwan, Shui Shan Lee
HIV testing is the gateway to biomedical means of prevention and treatment. Identifying predictors of HIV testing is important to inform future preventive interventions. Of 444 men who have sex with men without known HIV infection enrolled in a study in Hong Kong, 64% had ever been HIV-tested. Testers were generally older, better educated, had a higher monthly income, and more likely self-identified as gay. Testers often used Internet and frequented saunas for sex networking, compared with non-testers attending bars, massage centres and public toilets...
November 10, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29119924/deaths-in-the-lesbian-gay-bisexual-and-transgender-united-kingdom-communities-associated-with-ghb-and-precursors
#2
John M Corkery, Barbara Loi, Hugh Claridge, Christine Goodair, Fabrizio Schifano
Background Misuse of gammahydroxybutrate (GHB) and its prodrugs gammabutyrolactone (GBL) and 1,4 butanediol (1,4-BD) has increased greatly since the early 1990s, particularly amongst lesbian, gay, bisexual and transgender (LGBT) individuals in recreational and sexual settings, e.g. 'chemsex'. Objective and method This paper presents an overview of GHB pharmacotoxicology and provides analyses of cases in the LGBT population associated with use of these substances extracted from the UK's National Programme on Substance Abuse Deaths database, to which notification is voluntary...
November 8, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/29114529/rehabilitation-training-in-artificially-heated-environment
#3
Ping-Chung Leung
Sauna has become a popular club house facility where the dweller enjoys relaxation. Some exercise groups like yoga and Qigong practitioners, are making use of the heated environment to achieve quicker and better results of trainings. Sauna therapy is producing a thermal stress through hyperthermia. The cardiovascular system readily responds by increasing the heart rate which can become double the resting stage within minutes and cardiac output may have a 70% increase. The body's surface response to heat leads to a 40% of decrease in peripheral vascular resistance, thus allowing rapid peripheral blood flow which is responsible for greater heat dispersal directly from the skin...
October 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29048215/sauna-exposure-leads-to-improved-arterial-compliance-findings-from-a-non-randomised-experimental-study
#4
Earric Lee, Tanjaniina Laukkanen, Setor K Kunutsor, Hassan Khan, Peter Willeit, Francesco Zaccardi, Jari A Laukkanen
Background Heat therapy has been suggested to improve cardiovascular function. However, the effects of hot sauna exposure on arterial compliance and the dynamics of blood flow and pressure have not been well documented. Thus, we investigated the short-term effects of sauna bathing on arterial stiffness and haemodynamics. Design The design was an experimental non-randomised study. Methods There were 102 asymptomatic participants (mean age, 51.9 years) who had at least one cardiovascular risk factor. Participants were exposed to a single sauna session (duration: 30 min; temperature: 73℃; humidity: 10-20%)...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28979654/the-burden-of-illness-of-erythematotelangiectatic-rosacea-and-papulopustular-rosacea-findings-from-a-web-based-survey
#5
James Q Del Rosso, Emil A Tanghetti, Hilary E Baldwin, David A Rodriguez, Ilia L Ferrusi
Objective: Evaluate patients' perceptions of rosacea symptoms and treatments. Design: Cross-sectional, web-based survey conducted from May 8 to July 1,2015. Setting: E-mail invitation. Participants: Male and female adults in the United States who self-reported having a physician's diagnosis of rosacea. Measurements: Sociodemographic and clinical characteristics were collected for eligible respondents using the Self-Assessment of Rosacea Facial Redness scale and the Symptom Assessment for Rosacea Facial Bumps and Pimples questionnaire...
June 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28978590/liver-transplantation-for-non-exertional-heat-stroke-related-acute-liver-failure
#6
Sandra Coenen, Khe Tran, Jubi de Haan, Rob de Man
Heat stroke is a life-threatening condition characterised by hyperthermia leading to multiple organ dysfunction. Acute liver failure is a rare and potentially fatal consequence of heat stroke. Management of heat stroke is mainly supportive but liver transplantation can be considered as the treatment of acute liver failure in heat stroke. However, literature on liver transplantation as a treatment for acute liver failure in heat stroke is scarce. Until now, no cases of liver transplantation for acute liver failure in non-exertional heat stroke have been reported...
October 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28972808/joint-associations-of-sauna-bathing-and-cardiorespiratory-fitness-on-cardiovascular-and-all-cause-mortality-risk-a-long-term-prospective-cohort-study
#7
Setor K Kunutsor, Hassan Khan, Tanjaniina Laukkanen, Jari A Laukkanen
PURPOSE: We aimed to evaluate the joint impact of cardiorespiratory fitness (CRF) and frequency of sauna bathing (FSB) on the risk of cardiovascular and all-cause mortality. DESIGN: CRF measured by respiratory gas analyses and sauna exposure were assessed at baseline in a prospective study of 2277 men. CRF was categorized as low and high (median cut-offs) and FSB as low and high (≤2 and 3-7 sessions/week, respectively). RESULTS: During a median follow-up of 26...
October 16, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/28904851/body-related-perspectives-and-weight-control-methods-of-korean-chinese-nursing-school-students-in-yanbian-china-a-pilot-study
#8
Jounghee Lee, Meixiang Jin, Heejung Son, Wenying Cui
OBJECTIVES: This study aimed at identifying the current nutrition knowledge, body-related perspectives, and weight control behaviors of Korean-Chinese college students. METHODS: We conducted a pilot study by employing a healthy weight education program targeting Korean-Chinese nursing school students at the Yanbian University of Science and Technology in Yanbian, China. RESULTS: This pilot study included 40 participants (38 women and 2 men; mean age, 20...
August 2017: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/28872677/immunogenicity-assessment-during-the-development-of-protein-therapeutics
#9
REVIEW
Amy S Rosenberg, Zuben E Sauna
OBJECTIVE: Here we provide a critical review of the state of the art with respect to non-clinical assessments of immunogenicity for therapeutic proteins. KEY FINDINGS: The number of studies on immunogenicity published annually has more than doubled in the last 5 years. The science and technology, which have reached a critical mass, provide multiple of non-clinical approaches (computational, in vitro, ex vivo and animal models) to first predict and then to modify or eliminate T-cell or B-cell epitopes via de-immunization strategies...
September 5, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28842615/a-model-of-exposure-to-extreme-environmental-heat-uncovers-the-human-transcriptome-to-heat-stress
#10
Abderrezak Bouchama, Mohammad Azhar Aziz, Saeed Al Mahri, Musa Nur Gabere, Meshan Al Dlamy, Sameer Mohammad, Mashael Al Abbad, Mohamed Hussein
The molecular mechanisms by which individuals subjected to environmental heat stress either recover or develop heat-related complications are not well understood. We analysed the changes in blood mononuclear gene expression patterns in human volunteers exposed to extreme heat in a sauna (temperature of 75.7 ± 0.86 °C). Our analysis reveals that expression changes occur rapidly with no significant increase in core temperature and continue to amplify one hour after the end of heat stress. The reprogramed transcriptome was predominantly inhibitory, as more than two-thirds of the expressed genes were suppressed...
August 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28748097/multiple-organ-dysfunction-due-to-heatstroke-after-sauna-case-report-and-review-of-the-literature
#11
Yan Zhuang, Lin-Feng Dai, Ren-Zheng Diao
Heatstroke usually occurs in summer during heat waves, and few cases occur in winter. We report the case of a 26-year-old man who went through multiple organ dysfunction after sauna in January, and finally was diagnosed as heatstroke.
July 2017: JRSM Open
https://www.readbyqxmd.com/read/28739443/sauna-exposure-immediately-prior-to-short-term-heat-acclimation-accelerates-phenotypic-adaptation-in-females
#12
Jessica A Mee, Sophie Peters, Jonathan H Doust, Neil S Maxwell
OBJECTIVES: Investigate whether a sauna exposure prior to short-term heat acclimation (HA) accelerates phenotypic adaptation in females. DESIGN: Randomised, repeated measures, cross-over trial. METHODS: Nine females performed two 5-d HA interventions (controlled hyperthermia Tre≥38.5°C), separated by 7-wk, during the follicular phase of the menstrual cycle confirmed by plasma concentrations of 17-β estradiol and progesterone. Prior to each 90-min HA session participants sat for 20-min in either a temperate environment (20°C, 40% RH; HAtemp) wearing shorts and sports bra or a hot environment (50°C, 30% RH) wearing a sauna suit to replicate sauna conditions (HAsauna)...
July 4, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28692389/evaluation-of-the-components-of-the-north-carolina-syndromic-surveillance-system-heat-syndrome-case-definition
#13
Laurel Harduar Morano, Anna E Waller
OBJECTIVES: To improve heat-related illness surveillance, we evaluated and refined North Carolina's heat syndrome case definition. METHODS: We analyzed North Carolina emergency department (ED) visits during 2012-2014. We evaluated the current heat syndrome case definition (ie, keywords in chief complaint/triage notes or International Classification of Diseases, Ninth Revision, Clinical Modification [ ICD-9-CM] codes) and additional heat-related inclusion and exclusion keywords...
July 2017: Public Health Reports
https://www.readbyqxmd.com/read/28668284/is-there-a-role-for-diaphoresis-therapy-for-advanced-chronic-kidney-disease-patients
#14
REVIEW
Norio Hanafusa, Bereket Tessema Lodebo, Anuja Shah, Joel D Kopple
Diaphoresis therapy to remove water and solutes for the treatment of advanced chronic kidney disease (CKD) and chronic dialysis patients is an inadequately characterized treatment that was first reported over 50 years ago. Intensive diaphoresis, induced by heat treatment with saunas (dry heat) or hot baths (wet heat), can substantially increase cutaneous losses of water, urea, sodium, potassium, chloride, lactate, and possibly other solutes. How effectively diaphoresis therapy might remove many uremic toxins is not known...
September 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/28633297/sauna-bathing-and-incident-hypertension-a-prospective-cohort-study
#15
Francesco Zaccardi, Tanjaniina Laukkanen, Peter Willeit, Setor K Kunutsor, Jussi Kauhanen, Jari A Laukkanen
BACKGROUND: Sauna bathing is associated with reduced cardiovascular risk, but the mechanisms underlying this beneficial effect are not entirely understood. We aimed to assess the relationship between sauna bathing and risk of incident hypertension. METHODS: Frequency of sauna bathing was ascertained using questionnaires in the Kuopio Ischemic Heart Disease Study, a prospective cohort study conducted in Eastern Finland that comprised a population-based sample of 1,621 men aged 42 to 60 years without hypertension at baseline...
November 1, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28396061/-chromomycosis-acquired-in-a-non-tropical-area-a-case-report
#16
M S Ouédraogo, M-D Vignon-Pennamen, M Battistella, A Levy, M Feuilhade de Chauvin, A Petit
BACKGROUND: Chromomycosis, or chromoblastomycosis, is caused by cutaneous inoculation of dematiaceous fungi of telluric or plant origin. It is generally seen in tropical or subtropical zones. Treatment of the condition is known to be complex. Herein we report a case of chromomycosis contracted in a temperate region of Eastern Europe/Central Asia that was effectively treated with oral itraconazole and terbinafine in combination with cryotherapy. PATIENTS AND METHODS: A 44-year-old immunocompetent male subject consulted for a lesion on the buttocks that he had sustained 16 years earlier, and which, although never previously treated, had only become troublesome within the last few months...
April 7, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28386935/exit-site-care-in-the-netherlands-the-use-of-guidelines-in-practice
#17
Bettie P Hoekstra, Anneke de Vries-Hoogsteen, Bieneke Winkels, Helma Zevenbergen-Osinga, Ingrid Thijssen-Broers, Trian Bellemakers
BACKGROUND: The aim of this paper is to describe the quality of exit site care by evaluating the use of the Dutch exit site guideline over a period of 15 years. METHOD: The special interest group (SIG) for peritoneal dialysis (PD) analysed results of three surveys concerning general exit site care among members of the Dutch Association for nurses and carers (V&VN), the dialysis and nephrology section. RESULTS: In 2002 (when no guidelines were available) the survey showed huge diversity in practice, with no definition of the post-operative period after catheter placement and no uniform monitoring of the exit site...
September 2017: Journal of Renal Care
https://www.readbyqxmd.com/read/28378983/effects-of-sauna-bathing-on-stress-related-genes-expression-in-athletes-and-non-athletes
#18
Małgorzata Zychowska, Paweł Półrola, Grzegorz Chruściński, Jolanta Zielińska, Jolanta Góral-Półrola
INTRODUCTION AND OBJECTIVE: Heat stress induces the expression of genes encoding heat-shock proteins and immune response mediators. The aim of this study was to determine the differences in the expression of genes encoding heat-shock proteins 70 kDa and27 kDa, interleukin 6, interleukin 10and C-reactive protein, between athletes and non-athletes after sauna bathing. MATERIALS AND METHOD: Athletes (n=9) and non-athletes (n=9) were exposed to a Finnish sauna twice during one session at a temperature of 98...
March 21, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28364412/the-validation-and-evaluation-of-anti-hiv-testing-algorithm-used-in-mobile-clinic-setting-for-men-who-have-sex-with-men-in-metropolitan-bangkok-thailand
#19
Tippawan Pankam, Sarun Saensiriphan, Suphackok Areeyolwattana, Napapat Barisri, Supabhorn Pengnonyang, Sunee Sirivichayakul, Nittaya Phanuphak, Praphan Phanuphak
BACKGROUND: Same-day anti-HIV testing algorithm is recommended by Thai National Guidelines. We compared performance characteristics of algorithms used in a mobile clinic and a facility-based clinic for men who have sex with men (MSM) in Bangkok. METHODS: Mobile clinic samples collected from 4 saunas and 2 spa venues were tested by Alere DetermineTM HIV 1/2, followed by DoubleCheck GoldTM Ultra HIV 1/2 and SD Bioline HIV 1/2 3.0. All samples were re-tested at the Thai Red Cross Anonymous Clinic (TRCAC) by Architect HIV Ag/Ab or Elecsys HIV combi PT, followed by Alere DetermineTM HIV 1/2 and Serodia HIV 1/2...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28320639/exposure-to-polycyclic-aromatic-hydrocarbons-and-volatile-organic-compounds-among-recently-pregnant-rural-guatemalan-women-cooking-and-heating-with-solid-fuels
#20
John R Weinstein, Renée Asteria-Peñaloza, Anaité Diaz-Artiga, Gilberto Davila, S Katharine Hammond, Ian T Ryde, Joel N Meyer, Neal Benowitz, Lisa M Thompson
BACKGROUND: Household air pollution is a major contributor to death and disability worldwide. Over 95% of rural Guatemalan households use woodstoves for cooking or heating. Woodsmoke contains carcinogenic or fetotoxic polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs). Increased PAHs and VOCs have been shown to increase levels of oxidative stress. OBJECTIVE: We examined PAH and VOC exposures among recently pregnant rural Guatemalan women exposed to woodsmoke and compared exposures to levels seen occupationally or among smokers...
June 2017: International Journal of Hygiene and Environmental Health
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