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https://www.readbyqxmd.com/read/28748097/multiple-organ-dysfunction-due-to-heatstroke-after-sauna-case-report-and-review-of-the-literature
#1
Yan Zhuang, Lin-Feng Dai, Ren-Zheng Diao
Heatstroke usually occurs in summer during heat waves, and few cases occur in winter. We report the case of a 26-year-old man who went through multiple organ dysfunction after sauna in January, and finally was diagnosed as heatstroke.
July 2017: JRSM Open
https://www.readbyqxmd.com/read/28739443/sauna-exposure-immediately-prior-to-short-term-heat-acclimation-accelerates-phenotypic-adaptation-in-females
#2
Jessica A Mee, Sophie Peters, Jonathan H Doust, Neil S Maxwell
OBJECTIVES: Investigate whether a sauna exposure prior to short-term heat acclimation (HA) accelerates phenotypic adaptation in females. DESIGN: Randomised, repeated measures, cross-over trial. METHODS: Nine females performed two 5-d HA interventions (controlled hyperthermia Tre≥38.5°C), separated by 7-wk, during the follicular phase of the menstrual cycle confirmed by plasma concentrations of 17-β estradiol and progesterone. Prior to each 90-min HA session participants sat for 20-min in either a temperate environment (20°C, 40% RH; HAtemp) wearing shorts and sports bra or a hot environment (50°C, 30% RH) wearing a sauna suit to replicate sauna conditions (HAsauna)...
July 4, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28692389/evaluation-of-the-components-of-the-north-carolina-syndromic-surveillance-system-heat-syndrome-case-definition
#3
Laurel Harduar Morano, Anna E Waller
OBJECTIVES: To improve heat-related illness surveillance, we evaluated and refined North Carolina's heat syndrome case definition. METHODS: We analyzed North Carolina emergency department (ED) visits during 2012-2014. We evaluated the current heat syndrome case definition (ie, keywords in chief complaint/triage notes or International Classification of Diseases, Ninth Revision, Clinical Modification [ ICD-9-CM] codes) and additional heat-related inclusion and exclusion keywords...
July 2017: Public Health Reports
https://www.readbyqxmd.com/read/28668284/is-there-a-role-for-diaphoresis-therapy-for-advanced-chronic-kidney-disease-patients
#4
REVIEW
Norio Hanafusa, Bereket Tessema Lodebo, Anuja Shah, Joel D Kopple
Diaphoresis therapy to remove water and solutes for the treatment of advanced chronic kidney disease (CKD) and chronic dialysis patients is an inadequately characterized treatment that was first reported over 50 years ago. Intensive diaphoresis, induced by heat treatment with saunas (dry heat) or hot baths (wet heat), can substantially increase cutaneous losses of water, urea, sodium, potassium, chloride, lactate, and possibly other solutes. How effectively diaphoresis therapy might remove many uremic toxins is not known...
June 28, 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/28633297/sauna-bathing-and-incident-hypertension-a-prospective-cohort-study
#5
Francesco Zaccardi, Tanjaniina Laukkanen, Peter Willeit, Setor K Kunutsor, Jussi Kauhanen, Jari A Laukkanen
BACKGROUND: Sauna bathing is associated with reduced cardiovascular risk, but the mechanisms underlying this beneficial effect are not entirely understood. We aimed to assess the relationship between sauna bathing and risk of incident hypertension. METHODS: Frequency of sauna bathing was ascertained using questionnaires in the Kuopio Ischemic Heart Disease Study, a prospective cohort study conducted in Eastern Finland that comprised a population-based sample of 1,621 men aged 42 to 60 years without hypertension at baseline...
June 13, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28396061/-chromomycosis-acquired-in-a-non-tropical-area-a-case-report
#6
M S Ouédraogo, M-D Vignon-Pennamen, M Battistella, A Levy, M Feuilhade de Chauvin, A Petit
BACKGROUND: Chromomycosis, or chromoblastomycosis, is caused by cutaneous inoculation of dematiaceous fungi of telluric or plant origin. It is generally seen in tropical or subtropical zones. Treatment of the condition is known to be complex. Herein we report a case of chromomycosis contracted in a temperate region of Eastern Europe/Central Asia that was effectively treated with oral itraconazole and terbinafine in combination with cryotherapy. PATIENTS AND METHODS: A 44-year-old immunocompetent male subject consulted for a lesion on the buttocks that he had sustained 16 years earlier, and which, although never previously treated, had only become troublesome within the last few months...
April 7, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28386935/exit-site-care-in-the-netherlands-the-use-of-guidelines-in-practice
#7
Bettie P Hoekstra, Anneke de Vries-Hoogsteen, Bieneke Winkels, Helma Zevenbergen-Osinga, Ingrid Thijssen-Broers, Trian Bellemakers
BACKGROUND: The aim of this paper is to describe the quality of exit site care by evaluating the use of the Dutch exit site guideline over a period of 15 years. METHOD: The special interest group (SIG) for peritoneal dialysis (PD) analysed results of three surveys concerning general exit site care among members of the Dutch Association for nurses and carers (V&VN), the dialysis and nephrology section. RESULTS: In 2002 (when no guidelines were available) the survey showed huge diversity in practice, with no definition of the post-operative period after catheter placement and no uniform monitoring of the exit site...
September 2017: Journal of Renal Care
https://www.readbyqxmd.com/read/28378983/effects-of-sauna-bathing-on-stress-related-genes-expression-in-athletes-and-non-athletes
#8
Małgorzata Zychowska, Paweł Półrola, Grzegorz Chruściński, Jolanta Zielińska, Jolanta Góral-Półrola
INTRODUCTION AND OBJECTIVE: Heat stress induces the expression of genes encoding heat-shock proteins and immune response mediators. The aim of this study was to determine the differences in the expression of genes encoding heat-shock proteins 70 kDa and27 kDa, interleukin 6, interleukin 10and C-reactive protein, between athletes and non-athletes after sauna bathing. MATERIALS AND METHOD: Athletes (n=9) and non-athletes (n=9) were exposed to a Finnish sauna twice during one session at a temperature of 98...
March 21, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28364412/the-validation-and-evaluation-of-anti-hiv-testing-algorithm-used-in-mobile-clinic-setting-for-men-who-have-sex-with-men-in-metropolitan-bangkok-thailand
#9
Tippawan Pankam, Sarun Saensiriphan, Suphackok Areeyolwattana, Napapat Barisri, Supabhorn Pengnonyang, Sunee Sirivichayakul, Nittaya Phanuphak, Praphan Phanuphak
BACKGROUND: Same-day anti-HIV testing algorithm is recommended by Thai National Guidelines. We compared performance characteristics of algorithms used in a mobile clinic and a facility-based clinic for men who have sex with men (MSM) in Bangkok. METHODS: Mobile clinic samples collected from 4 saunas and 2 spa venues were tested by Alere DetermineTM HIV 1/2, followed by DoubleCheck GoldTM Ultra HIV 1/2 and SD Bioline HIV 1/2 3.0. All samples were re-tested at the Thai Red Cross Anonymous Clinic (TRCAC) by Architect HIV Ag/Ab or Elecsys HIV combi PT, followed by Alere DetermineTM HIV 1/2 and Serodia HIV 1/2...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28320639/exposure-to-polycyclic-aromatic-hydrocarbons-and-volatile-organic-compounds-among-recently-pregnant-rural-guatemalan-women-cooking-and-heating-with-solid-fuels
#10
John R Weinstein, Renée Asteria-Peñaloza, Anaité Diaz-Artiga, Gilberto Davila, S Katharine Hammond, Ian T Ryde, Joel N Meyer, Neal Benowitz, Lisa M Thompson
BACKGROUND: Household air pollution is a major contributor to death and disability worldwide. Over 95% of rural Guatemalan households use woodstoves for cooking or heating. Woodsmoke contains carcinogenic or fetotoxic polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs). Increased PAHs and VOCs have been shown to increase levels of oxidative stress. OBJECTIVE: We examined PAH and VOC exposures among recently pregnant rural Guatemalan women exposed to woodsmoke and compared exposures to levels seen occupationally or among smokers...
June 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28166609/modulating-immunogenicity-of-factor-ix-by-fusion-to-an-immunoglobulin-fc-domain-a-study-using-a-hemophilia-b-mouse-model
#11
D Levin, H A D Lagassé, E Burch, S Strome, S Tan, H Jiang, Z E Sauna, B Golding
Essentials Fc-fusion increases a therapeutic's half-life, but FcγR interactions may impact immunogenicity. Species-specific Fc-FcγR interactions allow for mechanistic in vivo studies using mouse models. Fc fusion modulates the immune response to factor IX in hemophilia B mice by eliciting Th1 bias. This model could inform future studies of IgE-associated anaphylaxis in hemophilia B patients. SUMMARY: Background Fc fusion is a platform technology used to increase the circulating half-life of protein and peptide therapeutics...
April 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28095955/preconditioning-to-reduce-decompression-stress-in-scuba-divers
#12
Peter Germonpré, Costantino Balestra
BACKGROUND: Using ultrasound imaging, vascular gas emboli (VGE) are observed after asymptomatic scuba dives and are considered a key element in the potential development of decompression sickness (DCS). Diving is also accompanied with vascular dysfunction, as measured by flow-mediated dilation (FMD). Previous studies showed significant intersubject variability to VGE for the same diving exposure and demonstrated that VGE can be reduced with even a single pre-dive intervention. Several preconditioning methods have been reported recently, seemingly acting either on VGE quantity or on endothelial inflammatory markers...
February 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28077675/post-hoc-assessment-of-the-immunogenicity-of-bioengineered-factor-viia-demonstrates-the-use-of-preclinical-tools
#13
Kasper Lamberth, Stine Louise Reedtz-Runge, Jonathan Simon, Ksenia Klementyeva, Gouri Shankar Pandey, Søren Berg Padkjær, Véronique Pascal, Ileana R León, Charlotte Nini Gudme, Søren Buus, Zuben E Sauna
Immunogenicity is an important consideration in the licensure of a therapeutic protein because the development of neutralizing anti-drug antibodies (ADAs) can affect both safety and efficacy. Neoantigens introduced by bioengineering of a protein drug are a particular cause for concern. The development of a bioengineered recombinant factor VIIa (rFVIIa) analog was discontinued after phase 3 trials because of the development of ADAs. The unmodified parent molecule (rFVIIa), on the other hand, has been successfully used as a drug for more than two decades with no reports of immunogenicity in congenital hemophilia patients with inhibitors...
January 11, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28035584/from-lab-to-real-world-heat-acclimation-considerations-for-elite-athletes
#14
Julia R Casadio, Andrew E Kilding, James D Cotter, Paul B Laursen
As major sporting events are often held in hot environments, increased interest in ways of optimally heat acclimating athletes to maximise performance has emerged. Heat acclimation involves repeated exercise sessions in hot conditions that induce physiological and thermoregulatory adaptations that attenuate heat-induced performance impairments. Current evidence-based guidelines for heat acclimation are clear, but the application of these recommendations is not always aligned with the time commitments and training priorities of elite athletes...
August 2017: Sports Medicine
https://www.readbyqxmd.com/read/28008544/the-where-and-how-for-reaching-transgender-women-and-men-who-have-sex-with-men-with-hiv-prevention-services-in-guatemala
#15
William M Miller, William C Miller, Clare Barrington, Sharon S Weir, Sanny Y Chen, Michael E Emch, Audrey E Pettifor, Gabriela Paz-Bailey
This study aims to describe the transgender women and men who have sex with men (MSM) missed through venue-based sampling and illustrate how data on venues can be used to prioritize service delivery. Respondent-driven sampling (RDS) and time-location sampling (TLS) were used concurrently in 2010 for behavioral surveillance among MSM and transgender women in Guatemala City. RDS recruits who did not frequent venues (n = 106) were compared to TLS recruits (n = 609). TLS participants recruited at different types of venues were compared...
December 22, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/28007939/single-synonymous-mutation-in-factor-ix-alters-protein-properties-and-underlies-haemophilia-b
#16
Vijaya L Simhadri, Nobuko Hamasaki-Katagiri, Brian C Lin, Ryan Hunt, Sujata Jha, Sandra C Tseng, Andrew Wu, Amber A Bentley, Ran Zichel, Qi Lu, Lily Zhu, Darón I Freedberg, Dougald M Monroe, Zuben E Sauna, Robert Peters, Anton A Komar, Chava Kimchi-Sarfaty
BACKGROUND: Haemophilia B is caused by genetic aberrations in the F9 gene. The majority of these are non-synonymous mutations that alter the primary structure of blood coagulation factor IX (FIX). However, a synonymous mutation c.459G>A (Val107Val) was clinically reported to result in mild haemophilia B (FIX coagulant activity 15%-20% of normal). The F9 mRNA of these patients showed no skipping or retention of introns and/or change in mRNA levels, suggesting that mRNA integrity does not contribute to the origin of the disease in affected individuals...
December 22, 2016: Journal of Medical Genetics
https://www.readbyqxmd.com/read/27932366/sauna-bathing-is-inversely-associated-with-dementia-and-alzheimer-s-disease-in-middle-aged-finnish-men
#17
Tanjaniina Laukkanen, Setor Kunutsor, Jussi Kauhanen, Jari Antero Laukkanen
Background: there are no previous studies linking repeated heat exposure of sauna and the risk of memory diseases. We aimed to investigate whether frequency of sauna bathing is associated with risk of dementia and Alzheimer's disease. Setting: prospective population-based study. Methods: the frequency of sauna bathing was assessed at baseline in the Kuopio Ischaemic Heart Disease population-based prospective cohort study of 2,315 apparently healthy men aged 42-60 years at baseline, with baseline examinations conducted between 1984 and 1989...
March 1, 2017: Age and Ageing
https://www.readbyqxmd.com/read/27908322/-traumatic-bilateral-posterior-shoulder-dislocation-after-a-seizure
#18
Mazaher Azizpour, Peter Anton Suder, Rebekka Fonnesbæk
We report a rare case in which a 52-year-old man was found lying on the floor of a sauna. He was confused and complained of pain in both shoulders. He had previously had surgery of a benign meningioma. The initial X-ray examination of both shoulders showed bilateral posterior shoulder dislocation, but no fractures were detected. An attempt to reposition the shoulder dislocation was performed but with no success. Intraoperative examination on the next day detected bilateral fractures with partially destroyed joint head...
November 28, 2016: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/27893354/summary-report-of-the-first-international-conference-on-inhibitors-in-haemophilia-a
#19
Sebastien Lacroix-Desmazes, David W Scott, Jenny Goudemand, Marijke Van Den Berg, Michael Makris, Alice S Van Velzen, Elena Santagostino, David Lillicrap, Frits R Rosendaal, Anneliese Hilger, Zuben E Sauna, Johannes Oldenburg, Lorenzo Mantovani, M Elisa Mancuso, Craig Kessler, Charles R M Hay, Paul Knoebl, Giovanni Di Minno, Keith Hoots, Amanda Bok, Mark Brooker, Erica Buoso, Pier Mannuccio Mannucci, Flora Peyvandi
No abstract text is available yet for this article.
November 25, 2016: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27855485/active-targeted-hiv-testing-and-linkage-to-care-among-men-who-have-sex-with-men-attending-a-gay-sauna-in-thailand
#20
Thana Khawcharoenporn, Anucha Apisarnthanarak, Nittaya Phanuphak
Existing data on the feasibility of human immunodeficiency virus (HIV) testing and counseling (HTC) and linkage to care among men who have sex with men (MSM) in hotspots are currently limited. A prospective study on active targeted HTC and linkage to care among MSM (≥18 years old) was conducted at a gay sauna in Thailand from November 2013 to October 2015. HIV risks and risk perception were evaluated through an anonymous survey. HIV testing with result notification and care appointment arrangement were provided on-site...
March 2017: AIDS Care
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