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https://www.readbyqxmd.com/read/27910775/hepatoprotective-effects-and-mechanisms-of-action-of-triterpenoids-from-lingzhi-or-reishi-medicinal-mushroom-ganoderma-lucidum-agaricomycetes-on-%C3%AE-amanitin-induced-liver-injury-in-mice
#1
Huihui Wu, Shanshan Tang, Zhaoqin Huang, Qian Zhou, Ping Zhang, Zuohong Chen
Most fatal mushroom poisonings are caused by species of the genus Amanita; the amatoxins are responsible for acute liver failure and death in humans. Ganoderma lucidum is a well-known traditional medicinal mushroom that has been shown to have obvious hepatoprotective effects. This study evaluated the hepatoprotective effects of triterpenoids from G. lucidum on liver injury induced by a-amanitin (α-AMA) in mice and the mechanisms of action of these triterpenoids, including radical scavenging and antiapoptosis activities...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27910768/pharmacological-properties-of-biocompounds-from-spores-of-the-lingzhi-or-reishi-medicinal-mushroom-ganoderma-lucidum-agaricomycetes-a-review
#2
Carlos Ricardo Soccol, Lucas Yamasaki Bissoqui, Cristine Rodrigues, Rosalia Rubel, Sandra R B R Sella, Fan Leifa, Luciana Porto de Souza Vandenberghe, Vanete Thomaz Soccol
Ganoderma lucidum is a well-known representative of mushrooms that have been used in traditional Chinese medicine for centuries. New discoveries related to this medicinal mushroom and its biological properties are frequently reported. However, only recently have scientists started to pay special attention to G. lucidum spores. This is in part because of the recent development of methods for breaking the spore wall and extracting biocompounds from the spore. Although some research groups are working with G. lucidum spores, data in the literature are still limited, and the methods used have not been systematized...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27910761/investigation-of-requisites-for-the-optimal-mycelial-growth-of-the-lingzhi-or-reishi-medicinal-mushroom-ganoderma-lucidum-agaricomycetes-on-oil-palm-biomass-in-malaysia
#3
Surya Sudheer, Asgar Ali, Sivakumar Manickam
Rigorous research has been carried out regarding the cultivation of Ganoderma lucidum using different agricultural residues. Nevertheless, large-scale cultivation and the separation of active compounds of G. lucidum are still challenges for local farmers. The objective of this study was to evaluate the use of oil palm waste fibers such as empty fruit bunch fibers and mesocarp fibers as effective substrates for the growth of G. lucidum mycelia to study the possibility of solid-state cultivation and to determine the optimum conditions necessary for the growth of mycelia of this mushroom on these waste fibers...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27685898/ganoderma-lucidum-reishi-mushroom-and-cancer
#4
Ahmet Unlu, Erdinc Nayir, Onder Kirca, Mustafa Ozdogan
Having a long historical past in traditional Chinese medicine, Ganoderma Lucidum (G. Lucidum) is a type of mushroom believed to extend life and promote health. Due to the increasing consumption pattern, it has been cultivated and marketed intensively since the 1970s. It is claimed to be effective in the prevention and treatment of many diseases, and in addition, it exerts anticancer properties. Almost all the data on the benefits of G. Lucidum are based on laboratory and preclinical studies. The few clinical studies conducted are questionable...
July 2016: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/27649602/pharmacokinetic-studies-of-ganoderic-acids-from-the-lingzhi-or-reishi-medicinal-mushroom-ganoderma-lucidum-agaricomycetes-by-lc-ms-ms
#5
Chun-Ru Cheng, Jie Ding, Yi Yang, Xin-Yong Liang, De-An Guo, Min Yang, Shu-Hong Guan
Ganoderma lucidum is a famous medicinal mushroom that has been widely used in clinical practice and as a dietary supplementa. The triterpenoid ganoderic acids are the main constituents of G. lucidum. To determine the pharmacokinetic characteristics of ganoderic acids, we developed and validated a sensitive and selective liquid chromatography-tandem mass spectrometry method to determine simultaneously the concentration of 4 representative ganoderic acids in rat plasma after oral administration of the extract from G...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27353194/tactile-feedback-for-relief-of-deafferentation-pain-using-virtual-reality-system-a-pilot-study
#6
Yuko Sano, Naoki Wake, Akimichi Ichinose, Michihiro Osumi, Reishi Oya, Masahiko Sumitani, Shin-Ichiro Kumagaya, Yasuo Kuniyoshi
BACKGROUND: Previous studies have tried to relieve deafferentation pain (DP) by using virtual reality rehabilitation systems. However, the effectiveness of multimodal sensory feedback was not validated. The objective of this study is to relieve DP by neurorehabilitation using a virtual reality system with multimodal sensory feedback and to validate the efficacy of tactile feedback on immediate pain reduction. METHODS: We have developed a virtual reality rehabilitation system with multimodal sensory feedback and applied it to seven patients with DP caused by brachial plexus avulsion or arm amputation...
2016: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/27318294/determination-of-phenolic-constituents-in-echinacea-raw-materials-and-dietary-supplements-by-hplc-uv-collaborative-study
#7
Paula N Brown, Elizabeth M Mudge, Lori Paley
A collaborative study was conducted to evaluate an HPLC method for determining phenolic compounds in Echinacea spp. raw materials, powdered extracts, and tinctures. Eleven collaborating laboratories received three practice samples representing each matrix type, phenolic reference standards, eight test samples as blind duplicates, the validated analytical method, and instructions. Test samples included two raw materials, four extracts (including one in combination with astragalus and reishi), one ethanolic tincture in combination with goldenseal, and one glycerite tincture...
September 2016: Journal of AOAC International
https://www.readbyqxmd.com/read/27279539/screening-of-indian-lingzhi-or-reishi-medicinal-mushroom-ganoderma-lucidum-agaricomycetes-a-upc2-sqd-ms-approach
#8
Anuja Bhardwaj, Mousami Srivastava, Mamta Pal, Yogesh Kumar Sharma, Saikat Bhattacharya, Rajkumar Tulsawani, Ragumani Sugadev, Kshipra Misra
Oriental medicinal mushroom Ganoderma lucidum has been widely used for the promotion of health and longevity owing to its various bioactive constituents. Therefore, comprehending metabolomics of different G. lucidum parts could be of paramount importance for investigating their pharmacological properties. Ultra-performance convergence chromatography (UPC2) along with mass spectrometry (MS) is an emerging technique that has not yet been applied for metabolite profiling of G. lucidum. This study has been undertaken to establish metabolomics of the aqueous extracts of mycelium (GLM), fruiting body (GLF), and their mixture (GLMF) using ultra-performance convergence chromatography single quadrupole mass spectrometry (UPC2-SQD-MS)...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27045603/ganoderma-lucidum-reishi-mushroom-for-cancer-treatment
#9
REVIEW
Xingzhong Jin, Julieta Ruiz Beguerie, Daniel Man-Yeun Sze, Godfrey C F Chan
BACKGROUND: Ganoderma lucidum is a natural medicine that is widely used and recommended by Asian physicians and naturopaths for its supporting effects on immune system. Laboratory research and a handful of preclinical trials have suggested that G. lucidum carries promising anticancer and immunomodulatory properties. The popularity of taking G. lucidum as an alternative medicine has been increasing in cancer patients. However, there is no systematic review that has been conducted to evaluate the actual benefits of G...
April 5, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27044336/distinguishing-commercially-grown-ganoderma-lucidum-from-ganoderma-lingzhi-from-europe-and-east-asia-on-the-basis-of-morphology-molecular-phylogeny-and-triterpenic-acid-profiles
#10
Florian Hennicke, Zakaria Cheikh-Ali, Tim Liebisch, Jose G Maciá-Vicente, Helge B Bode, Meike Piepenbring
In China and other countries of East Asia, so-called Ling-zhi or Reishi mushrooms are used in traditional medicine since several centuries. Although the common practice to apply the originally European name 'Ganoderma lucidum' to these fungi has been questioned by several taxonomists, this is still generally done in recent publications and with commercially cultivated strains. In the present study, two commercially sold strains of 'G. lucidum', M9720 and M9724 from the company Mycelia bvba (Belgium), are compared for their fruiting body (basidiocarp) morphology combined with molecular phylogenetic analyses, and for their secondary metabolite profile employing an ultra-performance liquid chromatography-electrospray ionization mass spectrometry (UPLC-ESIMS) in combination with a high resolution electrospray ionization mass spectrometry (HR-ESI-MS)...
July 2016: Phytochemistry
https://www.readbyqxmd.com/read/26868374/resolution-of-cutaneous-sarcoidosis-following-topical-application-of-ganoderma-lucidum-reishi-mushroom
#11
Gulcan Saylam Kurtipek, Arzu Ataseven, Ercan Kurtipek, İlknur Kucukosmanoglu, Mustafa Rasid Toksoz
Ganoderma lucidum (reishi mushroom) has been used in traditional Chinese and Japanese medicine as a herbal remedy for over 2000 years. Studies have shown that G. lucidum has anti-allergic, anti-oxidant, anti-tumor, anti-viral, and anti-inflammatory properties. A review of the literature revealed that there were no studies examining the use of G. lucidum for the treatment of skin diseases. Here, we report the case of a 44-year-old male patient who used soap enriched with G. lucidum and goat's milk for 3 days in treating annular cutaneous sarcoidosis...
March 2016: Dermatology and Therapy
https://www.readbyqxmd.com/read/26559864/bioinformatic-identification-of-potential-micrornas-and-their-targets-in-the-lingzhi-or-reishi-medicinal-mushroom-ganoderma-lucidum-higher-basidiomycetes
#12
Da-Shuai Mu, Chenyang Li, Liang Shi, Xuchen Zhang, Ang Ren, Ming-Wen Zhao
MicroRNAs (miRNAs) are a class of small, endogenous, noncoding RNA molecules that negatively regulate gene expression at the transcriptional or the post-transcriptional level. Although a large number of miRNAs have been identified in many species, especially model plants and animals, miRNAs in fungi remain largely unknown. In this study, based on a database of expressed sequence tags in Ganoderma lucidum, 89 potential miRNAs were identified using computational methods. Real-time polymerase chain reaction analysis of miRNA-like samples prepared from G...
2015: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/26281550/-analysis-of-triterpenoids-in-ganoderma-lucidum-by-microwave-assisted-continuous-extraction
#13
Yan-fang Lu, Jing An, Ye Jiang
For further improving the extraction efficiency of microwave extraction, a microwave-assisted contijuous extraction (MACE) device has been designed and utilized. By contrasting with the traditional methods, the characteristics and extraction efficiency of MACE has also been studied. The method was validated by the analysis of the triterpenoids in Ganoderma lucidum. The extraction conditions of MACE were: using 95% ethanol as solvent, microwave power 200 W and radiation time 14.5 min (5 cycles). The extraction results were subsequently compared with traditional heat reflux extraction ( HRE) , soxhlet extraction (SE), ultrasonic extraction ( UE) as well as the conventional microwave extraction (ME)...
April 2015: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/26249953/the-description-of-a-new-species-polymastigos-javaensis-n-sp-annelida-capitellidae-from-the-segara-anakan-mangroves-central-java-indonesia
#14
Joko Pamungkas
A new species, Polymastigos javaensis n. sp., is described from sandy clay sediment (0-30 cm depth) of the Segara Anakan mangroves. The species is described based on the distribution of capillaries and hooks, and the form of the prostomium, thorax, abdomen, lateral organs, genital pores, branchiae and pygidium. Methyl green staining pattern was applied to examine the similarity between the material of this study and Green's material. Polymastigos javaensis n. sp. is the second species belonging to the genus Polymastigos, after P...
2015: Zootaxa
https://www.readbyqxmd.com/read/26211750/-investigation-of-metal-element-content-of-some-european-and-far-eastern-herbs
#15
Krisztina Süle, Dóra Kurucz, Ágnes Kajári, Zoltán May
INTRODUCTION: Metal elements and their excess intake have significant influence on general health. AIM: There is only little information how Far Eastern herbs resemble European's regarding their purity and essential metal element content. The aim of the authors was to determine metal elements in different Chinese and European herbs and extracts. METHOD: The studied European herbs included Calendula officinalis petals, Achillea millefolium, Epilobium parviflorum herba, Urtica dioica leaves, Crataegus monogyna flowers while Far Eastern herbs were Cordyceps sinensis, Ganoderma lucidum, Ginkgo biloba leaves, Panax ginseng and Curcuma longa roots...
August 2, 2015: Orvosi Hetilap
https://www.readbyqxmd.com/read/26082982/enhanced-production-of-polysaccharide-through-the-overexpression-of-homologous-uridine-diphosphate-glucose-pyrophosphorylase-gene-in-a-submerged-culture-of-lingzhi-or-reishi-medicinal-mushroom-ganoderma-lucidum-higher-basidiomycetes
#16
Sen-Lin Ji, Rui Liu, Meng-Fei Ren, Huan-Jun Li, Jun-Wei Xu
This study aimed to improve polysaccharide production by engineering the biosynthetic pathway in Ganoderma lucidum through the overexpression of the homologous UDP glucose pyrophosphorylase (UGP) gene. The effects of UGP gene overexpression on intracellular polysaccharide (IPS) content, extracellular polysaccharide (EPS) production, and transcription levels of 3 genes encoding the enzymes involved in polysaccharide biosynthesis, including phosphoglucomutase (PGM), UGP, and α-1,3-glucan synthase (GLS), were investigated...
2015: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/26058418/neurometabolic-effect-of-altaian-fungus-ganoderma-lucidum-reishi-mushroom-in-rats-under-moderate-alcohol-consumption
#17
Oleg B Shevelev, Andrey E Akulov, Anna S Dotsenko, Galina V Kontsevaya, Mariya A Zolotykh, Lyudmila A Gerlinskaya, Sergey G Veprev, Tat'yana N Goryachkovskaya, Natal'ya A Zhukova, Nikolay A Kolchanov, Sergey E Pel'tek, Mikhail P Moshkin
BACKGROUND: The medications produced from natural products are widely used as prophylactics for sickness induced by alcohol consumption. One such prophylactic is produced from the Reishi mushroom, Ganoderma lucidum. Because of the antioxidant properties of these preparations, we expect neuroprotective prophylactic effects of Reishi-based medications in alcohol-treated animals. METHODS: The Reishi (R) suspension was produced as water extract from Altaian mushrooms...
July 2015: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/25975107/-antiviral-properties-of-basidiomycetes-metabolites
#18
REVIEW
A V Avtonomova, L M Krasnopolskaya
The data on the antiviral action of the Ganoderma lucidum, Lentinus edodes, Grifola frondosa, Agaricus brasiliensis and other basidiomycetes metabolites are summurized. The metabolites of these species of basidiomycetes exhibit a direct antiviral effect on herpes simplex virus types I and II, human immunodeficiency virus (HIV), hepatitis B virus, vesicular stomatitis virus, influenza virus, Epstein-Barr virus, and others. Moreover, metabolites of basidiomycetes increased antiviral immunity.
2014: Antibiotiki i Khimioterapii︠a︡, Antibiotics and Chemoterapy [sic]
https://www.readbyqxmd.com/read/25963704/-a-case-of-synchronous-sigmoid-cancer-and-ureter-cancer
#19
REVIEW
Reishi Toshiyama, Masayoshi Tokuoka, Yoshihito Ide, Hiroyuki Yamato, Yoko Yamamoto, Mitsunobu Takeda, Yasushi Hashimoto, Jin Matsuyama, Shigekazu Yokoyama, Takashi Morimoto, Yukio Fukushima, Takashi Nomura, Ken Kodama, Yo Sasaki, Masashi Takeda
A 78-year-old-man visited a nearby doctor for treatment of hepatitis C and high blood pressure.He was diagnosed with right hydronephrosis by abdominal echography conducted in follow-up of hepatitis C treatment in November 2011; he was then introduced to our hospital for close inspection and medical treatment.We observed wall hyperplasia and narrowing of the lumen in the central sigmoid part by contrast-enhanced computed tomography (CT).The right ureter at the L4/5 level showed wall hyperplasia and a deep color, and the right ureter, renal pelvis, and calix were expanded on the head side...
April 2015: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/25954966/in-vitro-assessment-of-extracts-of-the-lingzhi-or-reishi-medicinal-mushroom-ganoderma-lucidum-higher-basidiomycetes-against-different-plant-pathogenic-fungi
#20
Mirza Nabeel Baig, Ahmad Ali Shahid, Muhammad Ali
Five isolates of the lingzhi or reishi medicinal mushroom Ganoderma lucidum (GL-1, GL-2, GL-3, GL-4, GL-5) were collected from different locations within and surrounding Lahore, Pakistan, to study the antifungal potential of their bioactive compounds. After studying morphology, different concentrations of the extracts were prepared in methanol and water using a Soxhlet extractor. Different cultures of fungal pathogens were acquired from the First Fungal Culture Bank of Pakistan, University of the Punjab, Lahore...
2015: International Journal of Medicinal Mushrooms
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