Zehra N Ozdemir, Osman Ilhan, Gulsum Ozet, Mesude Falay, Mustafa Yenerel, Tulin Tuglular, Mehmet Turgut, Birol Guvenc, Ali Unal, Orhan Ayyildiz, Neslihan Andic, Abdullah Hacihanefioglu, Fahri Sahin, Mehmet Sencan, Ridvan Ali, Guner H Ozsan, Rahsan Yildirim, Eyup N Tiftik, Anil Tombak, Ozan Salim, Emin Kaya, Olga M Akay, Vahap Okan, Mustafa Pehlivan, Guray Saydam
BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematopoietic stem cell disease that may lead to weakness and death of patients, if unrecognized and untreated. Although consensus guidelines were reviewed recently for the diagnostic screening of PNH with multi-parameter flow cytometry (FCM), until now, no study has investigated the efficiency of such clinical indications in older patients. METHODS: Overall, 20 centers participated in the study and a total of 1,689 patients were included, 313 of whom were at geriatric age and 1,376 were aged 18 - 64 years...
September 1, 2020: Clinical Laboratory