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https://www.readbyqxmd.com/read/28945049/-standardization-of-names-in-prescriptions-of-traditional-chinese-medicines
#1
Chao-Feng Li, Yu-Jun Zhang, Dong-He Fan, Meng-Jie Zhang, Xue Bai, Wen-Hua Yang, Shu-Ya Qi, Zhi-Jie Zhang, Chun-Miao Xue, Liu-Ying Mao, Jun-Ling Cao
Chinese medicine prescriptions are a type of medical documents written by doctors after they understand the patients' conditions for syndrome differentiation. Chinese medicine prescriptions are also the basis for pharmacy personnel to dispense medicines and guide patients to use drugs. It has the legal, technical and economic significances. Chinese medicine prescriptions contain such information of names, quantity and usage. Whether the names of drugs in Chinese medicine prescriptions are standardized or not is directly related to the safety and efficacy of the drugs...
January 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28945046/-analysis-of-on-medication-rules-for-qi-deficiency-and-blood-stasis-syndrome-of-chronic-heart-failure-based-on-data-mining-technology
#2
Qian Wang, Geng-Zhen Yao, Guang-Ming Pan, Jing-Yi Huang, Yi-Pei An, Xu Zou
To analyze the medication features and the regularity of prescriptions of traditional Chinese medicine in treating patients with Qi-deficiency and blood-stasis syndrome of chronic heart failure based on modern literature. In this article, CNKI Chinese academic journal database, Wanfang Chinese academic journal database and VIP Chinese periodical database were all searched from January 2000 to December 2015 for the relevant literature on traditional Chinese medicine treatment for Qi-deficiency and blood-stasis syndrome of chronic heart failure...
January 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28944983/oral-prolonged-release-oxycodone-naloxone-for-managing-pain-and-opioid-induced-constipation-a-review-of-the-evidence
#3
REVIEW
Bart J Morlion, Stefan A Mueller-Lissner, Renato Vellucci, Wojciech Leppert, Benoît C Coffin, Sara L Dickerson, Tony O'Brien
BACKGROUND: Opioids provide effective relief from moderate-to-severe pain and should be prescribed as part of a multifaceted approach to pain management when other treatments have failed. Fixed-dose oxycodone/naloxone prolonged-release tablets (OXN PR) were designed to address the opioid class effect of opioid-induced constipation (OIC) by combining the analgesic efficacy of oxycodone with the opioid receptor antagonist, naloxone, which has negligible systemic availability when administered orally...
September 25, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28944967/risk-for-chromosomal-aberrations-in-apparently-isolated-intra-uterine-growth-restriction-a-systematic-review
#4
REVIEW
Lena Sagi-Dain, Amir Peleg, Shlomi Sagi
OBJECTIVE: To perform a systematic review examining the risk of chromosomal aberrations in apparently isolated intra-uterine growth restriction (IUGR). METHODS: Search was conducted by research librarian in five databases. By independent screening of 2894 references, two investigators selected original studies examining the risk of chromosomal aberrations in apparently isolated IUGR diagnosed at the second and third trimesters using ultrasound. We excluded studies describing IUGR combined with additional fetal anomalies detected by ultrasound and those where fetuses with structural anomalies or aneuploidy were not reported...
September 25, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28944952/bypassing-agent-prophylaxis-in-people-with-hemophilia-a-or-b-with-inhibitors
#5
REVIEW
Chatree Chai-Adisaksopha, Sarah J Nevitt, Mindy L Simpson, Maissaa Janbain, Barbara A Konkle
BACKGROUND: People with hemophilia A or B with inhibitors are at high risk of bleeding complications. Infusion of bypassing agents, such as recombinant activated FVII (rFVIIa) and plasma-derived activated prothrombin complex concentrate, are suggested as alternative therapies to factor VIII (haemophilia A) or IX (haemophilia B) for individuals who no longer respond to these treatments because they develop inhibitory antibodies. The ultimate goal of treatment is to preserve the individual's joints, otherwise destroyed by recurrent bleeds...
September 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28944906/peptidome-analysis-of-amniotic-fluid-from-pregnancies-with-preeclampsia
#6
Yating Qian, Lei Zhang, Can Rui, Hongjuan Ding, Pengyuan Mao, Hongjie Ruan, Ruizhe Jia
Preeclampsia (PE), a life‑threatening, complicated pregnancy‑associated disease, has recently become a research focus in obstetrics. However, the peptidome of the amniotic fluid in PE patients has rarely been investigated. The present study used peptidomic profiling to perform a comparative analysis of human amniotic fluid between normal and PE pregnancies. Centrifugal ultrafiltration and liquid chromatography‑tandem mass spectrometry (LC‑MS/MS) was combined with isotopomeric dimethyl labels to gain a deeper understanding of the role of proteins and the peptidome in the onset of PE...
September 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944888/screening-of-potential-genes-contributing-to-the-macrocycle-drug-resistance-of-c-albicans-via-microarray-analysis
#7
Jing Yang, Wei Zhang, Jian Sun, Zhiqin Xi, Zusha Qiao, Jinyu Zhang, Yan Wang, Ying Ji, Wenli Feng
The aim of the present study was to investigate the potential genes involved in drug resistance of Candida albicans (C. albicans) by performing microarray analysis. The gene expression profile of GSE65396 was downloaded from the Gene Expression Omnibus, including a control, 15‑min and 45‑min macrocyclic compound RF59‑treated group with three repeats for each. Following preprocessing using RAM, the differentially expressed genes (DEGs) were screened using the Limma package. Subsequently, the Kyoto Encyclopedia of Genes and Genomes pathways of these genes were analyzed using the Database for Annotation, Visualization and Integrated Discovery...
September 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944843/microarray-and-bioinformatics-analyses-of-gene-expression-profiles-in-balb-c-murine-macrophage-polarization
#8
Li Jiang, Xueqin Li, Yingying Zhang, Mengying Zhang, Zongsheng Tang, Kun Lv
Macrophages possess the hallmark feature of plasticity, allowing them to undergo a dynamic transition between M1 and M2 polarized phenotypes. The aim of the present study was to screen for differentially-expressed genes (DEGs) that were associated with BALB/c murine macrophage polarization. The transcription profiles of three M1 and three M2 samples were obtained using microarray analysis. Based on the threshold of fold‑change >2.0 and P‑value <0.05, a total of 1,253 DEGs were identified, of which 696 were upregulated and 557 downregulated in M1 macrophages compared with M2 macrophages...
September 19, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944822/investigation-of-crucial-genes-and-micrornas-in-conventional-osteosarcoma-using-gene-expression-profiling-analysis
#9
Chuangang Peng, Qi Yang, Bo Wei, Baoming Yuan, Yong Liu, Yuxiang Li, Dawer Gu, Guochao Yin, Bo Wang, Dehui Xu, Xuebing Zhang, Daliang Kong
The present study aimed to screen potential genes associated with conventional osteosarcoma (OS) and obtain further information on the pathogenesis of this disease. The microarray dataset GSE14359 was downloaded from the Gene Expression Omnibus. A total of 10 conventional OS samples and two non‑neoplastic primary osteoblast samples in the dataset were selected to identify the differentially expressed genes (DEGs) using the Linear Models for Microarray Data package. The potential functions of the DEGs were predicted using Gene Ontology (GO) and pathway enrichment analyses...
September 18, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944771/the-spectrum-of-t-cell-metabolism-in-health-and-disease
#10
REVIEW
Glenn R Bantug, Lorenzo Galluzzi, Guido Kroemer, Christoph Hess
In healthy individuals, metabolically quiescent T cells survey lymph nodes and peripheral tissues in search of cognate antigens. During infection, T cells that encounter cognate antigens are activated and - in a context-specific manner - proliferate and/or differentiate to become effector T cells. This process is accompanied by important changes in cellular metabolism (known as metabolic reprogramming). The magnitude and spectrum of metabolic reprogramming as it occurs in T cells in the context of acute infection ensure host survival...
September 25, 2017: Nature Reviews. Immunology
https://www.readbyqxmd.com/read/28944747/suicide-related-behaviours-in-schizophrenia-in-china-a-comprehensive-meta-analysis
#11
M Dong, S B Wang, F Wang, L Zhang, G S Ungvari, C H Ng, X Meng, Z Yuan, G Wang, Y T Xiang
AIMS: Suicide-related behaviours are common in schizophrenia and are significantly associated with premature death. The objective of this meta-analysis study was to estimate the pooled prevalence of suicide-related behaviours in schizophrenia patients in China. METHODS: The relevant literature was searched systematically via the relevant electronic databases (PubMed, Embase, PsycINFO, Chinese National Knowledge Infrastructure, Wanfang Databases and Chinese Biological Medical Literature Database) from their inception until 14 September 2016...
September 25, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28944726/paying-for-cures-how-can-we-afford-it-managed-care-pharmacy-stakeholder-perceptions-of-policy-options-to-address-affordability-of-prescription-drugs
#12
Kai Yeung, Kangho Suh, Anirban Basu, Louis P Garrison, Aasthaa Bansal, Josh J Carlson
BACKGROUND: High-priced medications with curative potential, such as the newer hepatitis C therapies, have contributed to the recent growth in pharmaceutical expenditure. Despite the obvious benefits, health care decision makers are just beginning to grapple with questions of how to value and pay for curative therapies that may feature large upfront cost, followed by health benefits that are reaped over a patient's lifespan. Alternative policy options have been proposed to promote high value and financially sustainable use of these therapies...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28944631/-developing-the-role-of-head-nurses-in-promoting-evidence-based-practices-among-hospital-staff-nurses-160-an-integrative-literature-review
#13
Nathalie Larochelle, Line Beaudet
Introduction : application of evidence-based practice (EBP) by nurses is uneven and inconsistent. Background : characteristics related to head nurses and organizations influence their interventions to the detriment of EBP. Objectives : this integrative literature review informed by the knowledge-to-action (KTA) framework developed by Straus, Tetroe, and Graham (1) sought to identify the barriers and facilitators encountered by head nurses when implementing EBP among hospital staff nurses. It also sought to put in evidence interventions to promote lasting implementation of EBP...
April 19, 2017: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/28944603/the-effect-of-side-of-implantation-on-unilateral-cochlear-implant-performance-in-patients-with-prelingual-and-postlingual-sensorineural-hearing-loss-a-systematic-review
#14
Véronique J C Kraaijenga, Tyche C Derksen, Inge Stegeman, Adriana L Smit
OBJECTIVE: Cerebral lateralization of language processing leads to a right ear advantage in normal hearing subjects. The aim of this study was to present a systematic overview of the effect of implantation side on postoperative cochlear implant performance in patients with symmetrical severe to profound sensorineural hearing loss. DATA SOURCES: PubMed, Embase and The Cochrane Library databases. RESEARCH METHODS: Databases were searched from database inception up to January 9(th) 2017 for cochlear implant and side and all synonyms...
September 25, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28944594/effect-of-clonidine-on-the-efficacy-of-lignocaine-local-anesthesia-in-dentistry-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#15
REVIEW
Gowri Sivaramakrishnan, Kannan Sridharan
Alternatives to adrenaline with lignocaine local anesthesia, such as clonidine, have been trialed in various randomized, controlled trials. Therefore, the aim of the present systematic review was to compile the available evidence on using clonidine with lignocaine for dental anesthesia. Electronic databases were searched for eligible studies. A data-extraction form was created, extracted data were analyzed using non-Cochrane mode in RevMan 5.3 software. Heterogeneity between the studies were assessed using the forest plot, I(2) statistics (where >50% was considered to have moderate-to-severe heterogeneity), and χ(2) -test...
September 24, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28944513/preliminary-data-on-possible-protein-markers-of-parturition-in-cows
#16
J Wawrzykowski, M Franczyk, M Hoedemaker, M Pries, B Streuff, M Kankofer
Parturition is one of the most important events in reproduction. Regardless of many studies, exact time for pregnancy termination and onset of parturition is impossible to determine. The aim of this study was to describe and to compare protein profile of plasma from healthy pregnant cows (n = 6) at following five time points: 2 weeks, 1 week before, at parturition, 1 week and 2 weeks after parturition to search for possible protein markers of parturition. Plasma samples were analysed by 1D and 2D electrophoresis, and selected spots were identified by mass spectrometry...
September 24, 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28944509/diagnosis-and-treatment-of-patients-with-prostatic-abscess-in-the-post-antibiotic-era
#17
REVIEW
Anne Lenore Ackerman, Pooja S Parameshwar, Jennifer T Anger
We reviewed the pathogenesis, clinical presentation, treatment options and outcomes of prostatic abscess in the post-antibiotic era, focusing on how patient risk factors and the emergence of multidrug-resistant organisms influence management of the condition. A MEDLINE search for "prostate abscess" or "prostatic abscess" was carried out. Prostate abscess is no longer considered a consequence of untreated urinary infection; now, men with prostatic abscess are typically debilitated or immunologically compromised, with >50% of patients having diabetes...
September 24, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28944481/efficacy-of-dexmedetomidine-on-perioperative-morbidity-during-nasal-surgery-a-meta-analysis
#18
Se Hwan Hwang, Ho Seok Lee, Young Hoon Joo, Jae Hyun Seo, Jun Myung Kang
OBJECTIVES: The goal of this meta-analysis was to perform a systematic review of the literature on the effect of dexmedetomidine on perioperative morbidity following nasal surgery and on the adverse effects of dexmedetomidine. DATA SOURCES: MEDLINE, Scopus, and Cochrane Database of Systematic Reviews. REVIEW METHODS: Two authors independently searched scientific and medical databases from their inception of article collection to March 2017...
September 25, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28944461/hearing-aids-for-mild-to-moderate-hearing-loss-in-adults
#19
REVIEW
Melanie A Ferguson, Pádraig T Kitterick, Lee Yee Chong, Mark Edmondson-Jones, Fiona Barker, Derek J Hoare
BACKGROUND: The main clinical intervention for mild to moderate hearing loss is the provision of hearing aids. These are routinely offered and fitted to those who seek help for hearing difficulties. By amplifying and improving access to sounds, and speech sounds in particular, the aim of hearing aid use is to reduce the negative consequences of hearing loss and improve participation in everyday life. OBJECTIVES: To evaluate the effects of hearing aids for mild to moderate hearing loss in adults...
September 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28944453/personalised-digital-interventions-for-reducing-hazardous-and-harmful-alcohol-consumption-in-community-dwelling-populations
#20
REVIEW
Eileen Fs Kaner, Fiona R Beyer, Claire Garnett, David Crane, Jamie Brown, Colin Muirhead, James Redmore, Amy O'Donnell, James J Newham, Frank de Vocht, Matthew Hickman, Heather Brown, Gregory Maniatopoulos, Susan Michie
BACKGROUND: Excessive alcohol use contributes significantly to physical and psychological illness, injury and death, and a wide array of social harm in all age groups. A proven strategy for reducing excessive alcohol consumption levels is to offer a brief conversation-based intervention in primary care settings, but more recent technological innovations have enabled people to interact directly via computer, mobile device or smartphone with digital interventions designed to address problem alcohol consumption...
September 25, 2017: Cochrane Database of Systematic Reviews
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