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Lucie Molet, Matthieu Revest, Maxime Fournet, Erwan Donal, Martine Bonnaure-Mallet, Jacques Minet, Hervé Le Bars
Infectious endocarditis due to Cardiobacterium hominis is an uncommon event, accounting for less than 2% of all cases of infectious endocarditis. The infection of the tricuspid valve as it is reported here is extremely rare. We report the case of a tricuspid endocarditis due to Cardiobacterium hominis in a 56 year-old man who was admitted to hospital with pelvic and scapular pain. The diagnosis was established through positive blood cultures and echographic detection of a large tricuspid vegetation. Despite efficient antibiotic therapy, valve replacement was required...
October 6, 2016: Annales de Biologie Clinique
Graziela Aparecida Nogueira de Almeida Ribeiro, Helenice Brizolla Giampietro, Lídia Barbieri Belarmino, Wilson Salgado-Júnior
Background: The psychologist who works in bariatric surgery has a role to receive, evaluate, prepare and educate the patient who will undergo the surgical procedure. Psychological evaluation becomes important in so far as allows us to obtain data on personal and familiar history and allow tracing of possible psychopathology. Aim: To collect data on psychological evaluations of patients in a bariatric surgery service of a public hospital in order to describe the psychological profile of patients in this service...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
Yohan N'Guyen, Xavier Duval, Matthieu Revest, Matthieu Saada, Marie-Line Erpelding, Christine Selton-Suty, Coralie Bouchiat, François Delahaye, Catherine Chirouze, François Alla, Christophe Strady, Bruno Hoen
OBJECTIVE: To analyze the characteristics and outcome of infective endocarditis (IE) according to the time interval between IE first symptoms and diagnosis. METHODS: Among the IE cases of a French population-based epidemiological survey, patients having early-diagnosed IE (diagnosis of IE within 1 month of first symptoms) were compared to those having late-diagnosed IE (diagnosis of IE more than 1 month after first symptoms). RESULTS: Among the 486 definite-IE, 124 (25%) had late-diagnosed IE whereas others had early-diagnosed IE...
September 8, 2016: Annals of Medicine
P Braquet, F Alla, C Cornu, F Goehringer, L Piroth, C Chirouze, M Revest, C Lechiche, X Duval, V Le Moing
Staphylococcus aureus bacteraemia (SAB) is a frequent and deadly disease. Given the lack of a randomized trial, optimal first-line antibiotic treatment is still debated. Our aim was to identify prognostic factors in SAB patients and to analyse the impact of first-line antibiotics. The VIRSTA prospective cohort study was conducted in eight tertiary care centres in France. Consecutive incident adults in whom a blood culture drawn in participating centres grew S. aureus between April 2009 and October 2011 were prospectively followed for 12 weeks...
August 8, 2016: Clinical Microbiology and Infection
Rym Boudjemaa, Romain Briandet, Matthieu Revest, Cédric Jacqueline, Jocelyne Caillon, Marie-Pierre Fontaine-Aupart, Karine Steenkeste
Staphylococcus aureus is one of the most frequent pathogens responsible for biofilm-associated infections (BAI), and the choice of antibiotics to treat these infections remains a challenge for the medical community. In particular, daptomycin has been reported to fail against implant-associated S. aureus infections in clinical practice, while its association with rifampin remains a good candidate for BAI treatment. To improve our understanding of such resistance/tolerance toward daptomycin, we took advantage of the dynamic fluorescence imaging tools (time-lapse imaging and fluorescence recovery after photobleaching [FRAP]) to locally and accurately assess the antibiotic diffusion reaction in methicillin-susceptible and methicillin-resistant S...
August 2016: Antimicrobial Agents and Chemotherapy
Valérie Bordeau, Anne Cady, Matthieu Revest, Octavie Rostan, Mohamed Sassi, Pierre Tattevin, Pierre-Yves Donnio, Brice Felden
Staphylococcus aureus is a commensal bacterium and pathogen. Identifying biomarkers for the transition from colonization to disease caused by this organism would be useful. Several S. aureus small RNAs (sRNAs) regulate virulence. We investigated presence and expression of 8 sRNAs in 83 S. aureus strains from 42 patients with sepsis or septic shock and 41 asymptomatic colonized carriers. Small pathogenicity island sRNAs sprB and sprC were clade specific. Six sRNAs had variable expression not correlated with clinical status...
September 2016: Emerging Infectious Diseases
S Lavoue, G Le Gac, A Gacouin, M Revest, L Sohier, J Mouline, S Jouneau, E Flecher, P Tattevin, J-M Tadié
OBJECTIVE: To describe two cases of Panton-Valentine leukocidin-producing Staphylococcus aureus (PVL-SA) necrotizing pneumonia treated with ECMO, and complete pulmonary evaluation at six months. METHODS: Retrospective analysis of two patients presenting with severe PVL-SA pneumonia who both underwent complete respiratory function testing and chest CT scan six months after hospital discharge. RESULTS: Indications for ECMO were refractory hypoxia and left ventricular dysfunction associated with right ventricular dilatation...
September 2016: Médecine et Maladies Infectieuses
Simon Rouzé, Erwan Flécher, Matthieu Revest, Amedeo Anselmi, Marie Aymami, Antoine Roisné, Julien Guihaire, Jean Philippe Verhoye
BACKGROUND: We investigated our surgical strategy and clinical results in patients from active infective endocarditis (AIE) complicated by paravalvular involvement to determine the risk factors of early and late death and reoperation. METHODS: From October 1979 to December 2014, 955 patients underwent operations for AIE; among them 207 had AIE with paravalvular extension. The patients were a mean age of 59.9 ± 15.4 years, and 162 (78%) were male. Of these patients, 137 (66%) had isolated aortic valve endocarditis, and 138 (67%) had native valve endocarditis...
August 2016: Annals of Thoracic Surgery
Matthieu Revest, Gérald Egmann, Anthony Chapron, Stéphane Jouneau, Pierre Tattevin
No abstract text is available yet for this article.
May 2016: Journal of Thoracic Disease
M Daudin, P Tattevin, B Lelong, E Flecher, S Lavoué, C Piau, A Ingels, A Chapron, J-C Daubert, M Revest
Case series have suggested that pneumococcal endocarditis is a rare disease, mostly reported in patients with co-morbidities but no underlying valve disease, with a rapid progression to heart failure, and high mortality. We performed a case-control study of 28 patients with pneumococcal endocarditis (cases), and 56 patients with non-pneumococcal endocarditis (controls), not matched for sex and age, during the years 1991-2013, in one referral centre. Alcoholism (39.3% versus 10.7%; p <0.01), smoking (60.7% versus 21...
June 2016: Clinical Microbiology and Infection
Matthieu Revest, Gérald Egmann, Vincent Cattoir, Pierre Tattevin
The HACEK group of bacteria - Haemophilus parainfluenzae, Aggregatibacter spp. (A. actinomycetemcomitans, A. aphrophilus, A. paraphrophilus, and A. segnis), Cardiobacterium spp. (C. hominis, C. valvarum), Eikenella corrodens, and Kingella spp. (K. kingae, K. denitrificans) - are fastidious gram-negative bacteria, part of the normal microbiota of oral and upper respiratory tract in humans. Although their pathogenicity is limited, they are responsible for 1-3% of all infective endocarditis. HACEK endocarditis mostly affect patients with underlying heart disease or prosthetic valves, and are characterized by an insidious course, with a mean diagnosis delay of 1 month (Haemophilus spp...
2016: Expert Review of Anti-infective Therapy
M Revest, C Jacqueline, R Boudjemaa, J Caillon, V Le Mabecque, A Breteche, K Steenkeste, P Tattevin, G Potel, C Michelet, M P Fontaine-Aupart, D Boutoille
OBJECTIVE: Prosthetic vascular graft infection (PVGI) is an emerging disease, mostly caused by staphylococci, with limited data regarding efficacy of current antistaphylococcal agents. We aimed to assess the efficacy of different antibiotic regimens. METHODS: Six different strains of MSSA and MRSA were used. We compared results of minimal biofilm inhibitory and eradicating concentrations (MBICs and MBECs) obtained with a Calgary Biofilm Pin Lid Device (CBPD) with those yielded by an original Dacron(®)-related minimal inhibitory and eradicating concentration measure model...
May 2016: Journal of Antimicrobial Chemotherapy
P Fillâtre, M Revest, S Belaz, F Robert-Gangneux, J-R Zahar, F Roblot, P Tattevin
Pneumocystis jiroveci (formerly P. carinii) is an opportunistic fungus responsible for pneumonia in immunocompromised patients. Pneumocystosis in non-HIV-infected patients differs from AIDS-associated pneumocystosis in mostly two aspects: diagnosis is more difficult, and prognosis is worse. Hence, efforts should be made to target immunocompromised patients at higher risk of pneumocystosis, so that they are prescribed long-term, low-dose, trimethoprime-sulfamethoxazole, highly effective for pneumocystosis prophylaxis...
May 2016: La Revue de Médecine Interne
Harry Sokol, Tatiana Galperine, Nathalie Kapel, Pierre Bourlioux, Philippe Seksik, Frederic Barbut, Julien Scanzi, François Chast, Rui Batista, Francisca Joly, Anne-Christine Joly, Anne Collignon, Benoit Guery, Laurent Beaugerie
Faecal microbiota transplantation is effective for treating recurrent forms of Clostridium difficile infection and its use in this indication is recommended in the most recent European and North American guidelines. In this context, faecal microbiota transplantation is beginning to be performed in France in clinical practice, while the rules governing this procedure have been defined in France only for clinical trials. To unify, secure, and evaluate practice in this field in France, the French Group of Faecal microbiota Transplantation (FGFT) was created in October 2014 with the support of the French National Society of Gastroenterology, the French Infectious Disease Society, and the National Academy of Pharmacy...
March 2016: Digestive and Liver Disease
Tattevin Pierre, Lorleac'h Aurélien, Revest Matthieu
The spread of multidrug-resistant bacteria has accelerated sharply in the last decade. According to the World Health Organization they are responsible for an estimated 25 000 deaths in Europe each year. In addition, few new antibiotics are under development, raising the spectrum of a return to the "pre-antibiotic era". Non antibiotic antibacterial agents have recently attracted renewed interest. The most promising candidates are: i) phages (bacteria-infecting viruses) have been widely used in Eastern European countries since the 1930s but come up against logistic and regulatory obstacles due to the evolutionary nature of these biologic agents, while convincing clinical data are lacking; ii) bacteriocines are smallantibacterialpeptidesproducedby numerous bacteria; some have a rapid bactericidal effect, good tolerability, and a limited impact on the commensal flora; however, clinical use of bacteriocines is complicated by their fragility, poor penetration, and substantial risk of resistance selection ; iii) antisense oligonucleo tides act by inactivating genes through specific interaction with a complementary DNA or RNA fragment, potentially allowing specific inhibition of selected bacterial virulence factors...
March 2014: Bulletin de L'Académie Nationale de Médecine
Julien Guihaire, Matthieu Revest, Jean-François Heautot, Jean-Philippe Verhoye
Infectious arteritis is an insidious condition commonly associated with a long diagnostic delay. We report the management of extensive pneumococcal thoracic aortitis in a 64-year-old woman. The frozen elephant trunk procedure was performed to repair the aortic arch. Prolonged aortic wall cultures were positive for Streptococcus pneumoniae. Late follow-up imaging at 36 months demonstrated no sign of recurrence around the hybrid vascular graft in the thoracic aorta.
September 29, 2015: Asian Cardiovascular & Thoracic Annals
M Revest, F Camou, E Senneville, J Caillon, F Laurent, B Calvet, P Feugier, M Batt, C Chidiac
More than 400000 vascular grafts are inserted annually in the USA. Graft insertion is complicated by infection in 0.5-4% of cases. Vascular graft infections (VGIs) are becoming one of the most frequent prosthesis-related infections and are associated with considerable mortality, ranging from 10 to 25% within 30 days following the diagnosis. Treatment of VGI is based on urgent surgical removal of the infected graft followed by prolonged antibiotherapy. Data regarding the best antibiotherapy to use are lacking since no well designed trial to study antimicrobial treatment of VGI exists...
September 2015: International Journal of Antimicrobial Agents
Blandine Denis, Marguerite Guiguet, Nathalie de Castro, Frédéric Mechaï, Matthieu Revest, Giovanna Melica, Dominique Costagliola, Olivier Lortholary
BACKGROUND: Before the advent of combination antiretroviral therapy (cART), roughly 50% of cases of invasive aspergillosis (IA) associated with human immunodeficiency virus (HIV) infection involved individuals without classical predisposing host factors, and the median survival time was <4 months after diagnosis. We examined if the situation evolved over time using the revised European Organisation for Research and Treatment of Cancer/National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC) definition and analyzed survival trends after diagnosis over 20 years...
October 15, 2015: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Soléne Patrat-Delon, Adrien Rouxel, Arnaud Gacouin, Matthieu Revest, Erwan Flécher, Olivier Fouquet, Yves Le Tulzo, Nicolas Lerolle, Pierre Tattevin, Jean-Marc Tadié
OBJECTIVES: To better select for patients who most likely will benefit from cardiac surgery among those with infective endocarditis (IE), we aimed to identify preoperative markers associated with poor outcome after cardiac surgery for IE, and to evaluate the accuracy of European System for Cardiac Operative Risk Evaluation (EuroSCORE) II to predict mortality. METHODS: We enrolled all adult patients who underwent cardiac surgery during the acute phase of definite IE (Duke Criteria) in two referral centres for cardiac surgery...
March 2016: European Journal of Cardio-thoracic Surgery
Marie Aymami, Matthieu Revest, Caroline Piau, Céline Chabanne, François Le Gall, Bernard Lelong, Jean-Philippe Verhoye, Christian Michelet, Pierre Tattevin, Erwan Flécher
This study reports six consecutive patients who underwent heart transplantation as salvage treatment for endocarditis (Duke criteria) with extensive perivalvular lesions and end-stage heart failure. The median age was 45 years (range, 24 to 64), and the aortic valve was affected in all patients. Pathogens were Staphylococcus aureus (n = 2), Streptococcus pneumoniae (n = 2), Streptococcus agalactiae (n = 1), or not documented (n = 1). All patients survived, with no relapse, after a median follow-up of 24.5 months...
April 2015: Clinical Microbiology and Infection
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