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https://www.readbyqxmd.com/read/29035640/patients-acceptance-of-the-use-of-serious-games-in-physical-rehabilitation-in-morocco
#1
Bruno Bonnechère, Mélissa Van Vooren, Bart Jansen, Jan S Van Sint, Mohamed Rahmoun, Maryam Fourtassi
OBJECTIVE: The aim of this study was to determine whether serious games especially customized for physical rehabilitation could be used in daily clinics with patients who are not familiar with informatics and/or new technologies and whether such a clinical approach would be culturally acceptable within a North African population to plan further clinical distribution if the hypothesis appears to be positive. MATERIALS AND METHODS: Twenty-one patients participated in this study...
October 2017: Games for Health
https://www.readbyqxmd.com/read/29033973/comparison-of-central-ambulatory-home-and-office-blood-pressure-measurement-as-risk-markers-for-mild-cognitive-impairment-in-hypertensive-patients
#2
Teodora Yaneva-Sirakova, Latchezar Traykov, Julia Petrova, Dobrin Vassilev
AIMS: We compared the role of central blood pressure (BP), ambulatory BP monitoring (ABPM), home-measured BP (HMBP) and office BP measurement as risk markers for the development of mild cognitive impairment (MCI). METHODS: 70 hypertensive patients on combination medical therapy were studied. Their mean age was 64.97 ± 8.88 years. Eighteen (25.71%) were males and 52 (74.28%) females. All of the patients underwent full physical examination, laboratory screening, echocardiography, and office, ambulatory, home and central BP measurement...
May 2017: Dementia and Geriatric Cognitive Disorders Extra
https://www.readbyqxmd.com/read/29032727/spleen-derived-anti-inflammatory-cytokine-il-10-stimulated-by-adipose-tissue-derived-stem-cells-protects-against-type-2-diabetes
#3
JinYing Zhang, ZiHui Deng, LiYuan Jin, Chen Yang, Jiejie Liu, Haijing Song, Weidong Han, YiLing Si
Considering that spleen plays an important role in the occurrence and development of diabetes, we aimed to investigate the role of the spleen in the treatment of type 2 diabetes (T2D) with adipose tissue-derived stem cells (ADSCs). We established a T2D/splenectomy (SPX) rat model using high-fat diet/streptozotocin (STZ) administration with SPX, then assessed the therapeutic effects of ADSCs, and explored the possible mechanism. A single ADSCs infusion was found to ameliorate hyperglycemia and insulin resistance in diabetic rats, accompanied by a considerable number of ADSCs homing to the spleens in T2D rats...
October 15, 2017: Stem Cells and Development
https://www.readbyqxmd.com/read/29032299/association-of-antiplatelet-therapy-with-patient-outcomes-after-out-of-hospital-cardiac-arrest
#4
Alexandro Gianforcaro, Michael Kurz, Francis X Guyette, Clifton W Callaway, Jon C Rittenberger, Jonathan Elmer
BACKGROUND: Cessation of blood flow during out-of-hospital cardiac arrest (OHCA) results in microvascular thrombosis, protracted hypoperfusion after return of spontaneous circulation and damage to vital organs. We tested the hypothesis that pre-arrest antiplatelet and anticoagulant medication use would be associated with less post-arrest organ dysfunction and better outcomes. METHODS: We included OHCA patients treated from January 2005 to October 2014 at a single academic medical center...
October 11, 2017: Resuscitation
https://www.readbyqxmd.com/read/29031888/below-the-surface-parents-views-on-the-factors-that-influence-treatment-adherence-in-paediatric-burn-scar-management-a-qualitative-study
#5
Nicole Andrews, Laura L Jones, Naiem Moiemen, Melanie Calvert, Philip Kinghorn, Ian Litchfield, Jonathan Bishop, Jonathan J Deeks, Jonathan Mathers
INTRODUCTION: Parents have a crucial role to play in burn scar management for their children at a time that is extremely stressful for them and their child. Scar management treatments such as pressure garment therapy (PGT) require high levels of adherence. There has been a lack of research into the factors that may influence adherence in paediatric burn scar management. This qualitative research study has investigated parents' experiences of scar management and their attempts to adhere to treatment at home...
October 11, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29031173/an-unusual-case-of-transpelvic-impalement-injury-a-case-report
#6
Mushrek Alani, Saeed Mahmood, Ayman El-Menyar, Sajid Atique, Hassan Al-Thani, Ruben Peralta
INTRODUCTION: Impalement injury is a rare type of mechanical injury following forceful insertion of projecting object into the body. Careful planning for removal of the impaling object is essential to decrease the blood loss and preserve the function of the injured organ. PRESENTATION OF CASE: A 27 year-old male fell from 4m height over a U shaped projecting up metallic bar. The bar penetrated the left side of the pelvis and traversed through the left iliac bone causing a comminuted fracture in the supra-acetabular region extending to the left psoas muscle, injuring the viscera and causing fracture of the right femur...
October 5, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29030859/outpatient-parenteral-antimicrobial-therapy-in-enterococcus-faecalis-infective-endocarditis
#7
M V Gil-Navarro, L E Lopez-Cortes, R Luque-Marquez, J Galvez-Acebal, A de Alarcon-Gonzalez
WHAT IS KNOWN AND OBJECTIVE: Enterococcus faecalis is the third most common causal agent of infective endocarditis. Currently, the treatment recommended is a combination of ampicillin (2 g/4 h) plus ceftriaxone (2 g/12 h), so patients must remain hospitalized for almost 6 weeks to receive the treatment. They are not generally included in outpatient parenteral antimicrobial therapy programs because 2 different electronic pumps are required to administer these 2 antibiotics. To enable the treatment of patients with E...
October 13, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29030222/vascular-changes-in-tumors-resistant-to-a-vascular-disrupting-nanoparticle-treatment
#8
Shweta Sharma, Aman P Mann, Tarmo Mölder, Venkata Ramana Kotamraju, Robert Mattrey, Tambet Teesalu, Erkki Ruoslahti
Anti-angiogenic and vascular disrupting therapies rely on the dependence of tumors on new blood vessels to sustain tumor growth. We previously reported a potent vascular disrupting agent, a theranostic nanosystem consisting of a tumor vasculature-homing peptide (CGKRK) fused to a pro-apoptotic peptide [D(KLAKLAK)2] coated on iron oxide nanoparticles. This nanosystem showed promising therapeutic efficacy in glioblastoma (GBM) and breast cancer models. However, complete control of the tumors was not achieved, and some tumors became non-responsive to the treatment...
October 10, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29029665/mohs-micrographic-surgery-key-pharmacologic-considerations
#9
Diana Fischer, Patricia Orlando, Laura Shane-McWhorter
OBJECTIVE: To describe Mohs micrographic surgery and evaluate whether direct oral anticoagulants should be withheld in patients with atrial fibrillation (Afib) prior to the procedure and to consider what type of antibiotic prophylaxis should be used. SETTING: A community setting in which an elderly patient is living independently at home. PRACTICE DESCRIPTION: Academic-affiliated internal medicine clinic that cares for adult patients of all ages, including elderly patients living independently in their own home...
August 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/29027607/developing-a-patient-reported-outcome-measure-for-hiv-care-on-perceived-barriers-to-antiretroviral-adherence-assessing-the-needs-of-hiv-clinicians-through-qualitative-analysis
#10
Isabelle Toupin, Kim Engler, David Lessard, Leo Wong, Andràs Lènàrt, Bruno Spire, François Raffi, Bertrand Lebouché
PURPOSE: To identify HIV clinicians' needs for the clinical use of a new patient-reported outcome measure (PRO) on barriers to antiretroviral therapy (ART) adherence. METHODS: In 2015, five focus groups with 31 clinicians from France were transcribed, coded with Atlas.ti, and submitted to a typological analysis. RESULTS: The analysis identified seven patient profiles, each tied to distinct barriers to adherence and to specific needs for the PRO's content, data collection and transmission...
October 13, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/29024613/remote-monitoring-of-automated-peritoneal-dialysis-patients-assessing-clinical-and-economic-value
#11
Dilip Makhija, Mark Dominik Alscher, Stefan Becker, Silvia D'Alonzo, Raj Mehrotra, Leslie Wong, Kim McLeod, Judy Danek, Mary Gellens, Todd Kudelka, James A Sloand, Suzanne Laplante
BACKGROUND: For chronic kidney disease patients who progress to end-stage renal disease, survival is dependent on renal replacement therapy in the form of kidney transplantation or chronic dialysis. Peritoneal dialysis (PD), which can be performed at home, is both more convenient and less costly than hemodialysis that requires three 4-h visits per week to the dialysis facility and complicated equipment. Remote therapy management (RTM), technologies that collect medical information and transmit it to healthcare providers for patient management, has the potential to improve the outcomes of patients receiving automated peritoneal dialysis (APD) at home...
October 12, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29023191/use-of-nasogastric-feeding-tubes-for-children-at-home-a-template-for-caregiver-education
#12
Beth Lyman, Gina Rempel, Kerrin Windsor, Peggi Guenter
There is a lack of knowledge on the part of caregivers who need to place nasogastric (NG) tubes in children for enteral nutrition therapy. This article provides the rationale, best practices, and a template for caregiver education. Canadian and Australian programs have excellent patient education materials. They have shared these step-by-step procedures for healthcare professionals to provide to caregivers to whom they are teaching placement and care of NG tubes.
October 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29020478/photobiomodulation-therapy-for-androgenetic-alopecia-a-clinician-s-guide-to-home-use-devices-cleared-by-the-federal-drug-administration
#13
Erin M Dodd, Margo A Winter, Maria K Hordinsky, Neil S Sadick, Ronda S Farah
The market for home-use photobiomodulation devices to treat androgenetic alopecia has rapidly expanded, and the FDA has recently cleared many devices for this purpose. Patients increasingly seek dermatologists' advice regarding the safety and efficacy of these hair loss treatments. The purpose of this guide was threefold: 1) to identify all home-use photobiomodulation therapy devices with FDA-clearance for treatment of androgenetic alopecia; 2) to review device design, features and existing clinical evidence; and 3) to discuss practical considerations of photobiomodulation therapy, including patient suitability, treatment goals, safety, and device selection...
October 11, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29020202/rates-of-and-risk-factors-for-adverse-drug-events-in-outpatient-parenteral-antimicrobial-therapy
#14
Sara C Keller, Deborah Williams, Mitra Gavgani, David Hirsch, John Adamovich, Dawn Hohl, Ayse P Gurses, Sara E Cosgrove
Background: To better monitor patients on outpatient parenteral antimicrobial therapy (OPAT), we need an improved understanding of risk factors for and timing of OPAT-associated adverse drug events (ADEs). Methods: We undertook an analysis of a prospective cohort of patients discharged from two academic medical centers on OPAT. Patients underwent chart abstraction and a telephone survey. Multivariable analyses estimated adjusted incident rate ratios (aIRR) between clinical and demographic risk factors and clinician-determined clinically significant ADEs...
August 17, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29016747/five-year-trends-2008-2012-in-cardiac-implantable-electrical-device-utilization-in-five-european-nations-a-case-study-in-cross-country-comparisons-using-administrative-databases
#15
Helen Banks, Aleksandra Torbica, Cinzia Valzania, Yauheniya Varabyova, Valentina Prevolnik Rupel, Rod S Taylor, Theresa Hunger, Simon Walker, Giuseppe Boriani, Giovanni Fattore
Aims: Common methodologies for analysis of analogous data sets are needed for international comparisons of treatment and outcomes. This study tests using administrative hospital discharge (HD) databases in five European countries to investigate variation/trends in pacemaker (PM) and implantable cardioverter defibrillator (ICD) implant rates in terms of patient characteristics/management, device subtype, and initial implantation vs. replacement, and compares findings with existing literature and European Heart Rhythm Association (EHRA) reports...
June 14, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29016235/telemedicine-support-groups-for-home-parenteral-nutrition-users
#16
Eve-Lynn Nelson, Donna Macan Yadrich, Noreen Thompson, Shawna Wright, Kathaleen Stone, Natasia Adams, Marilyn Werkowitch, Carol E Smith
Patients receiving home parenteral nutrition (HPN), a life-sustaining intravenous (IV) infusion that provides nourishment and hydration to patients with short gut or inflammatory bowel diseases, are often isolated and not in visual contact with peers or health providers. One completed clinical trial (Clinical Trials.gov NCT0190028) and 1 ongoing clinical trial (Clinical Trials.gov NCT02987569) are evaluating a mobile videoconferencing-delivered support group intervention for patients on HPN and their caregivers...
October 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28994816/the-aortic-ring-co-culture-assay-a-convenient-tool-to-assess-the-angiogenic-potential-of-mesenchymal-stromal-cells-in-vitro
#17
Farwah Iqbal, Yarden S Gratch, Peter Szaraz, Clifford L Librach
Angiogenesis is a complex, highly regulated process responsible for providing and maintaining adequate tissue perfusion. Insufficient vasculature maintenance and pathological malformations can result in severe ischemic diseases, while overly abundant vascular development is associated with cancer and inflammatory disorders. A promising form of pro-angiogenic therapy is the use of angiogenic cell sources, which can provide regulatory factors as well as physical support for newly developing vasculature. Mesenchymal Stromal Cells (MSCs) are extensively investigated candidates for vascular regeneration due to their paracrine effects and their ability to detect and home to ischemic or inflamed tissues...
September 18, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28994304/an-exploration-of-the-experience-of-using-calendar-reminders-for-people-with-dementia-and-family-carers
#18
Nina Evans, Lesley Collier
People with dementia and family carers often use calendars to support time orientation to maintain routine. However, little is known about the use of calendars as a compensatory strategy. This study examines the experience and practicalities of using calendar reminders from the perspective of people with dementia and family carers. Six dyads were recruited and interviewed at home. Interpretative Phenomenological Analysis was used to develop a narrative interpreted from an occupational therapy perspective. The themes were reflected on during two subsequent focus groups...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/28993747/the-use-of-virtual-reality-facilitates-dialectical-behavior-therapy%C3%A2-observing-sounds-and-visuals-mindfulness-skills-training-exercises-for-a-latino-patient-with-severe-burns-a-case-study
#19
Jocelyn Gomez, Hunter G Hoffman, Steven L Bistricky, Miriam Gonzalez, Laura Rosenberg, Mariana Sampaio, Azucena Garcia-Palacios, Maria V Navarro-Haro, Wadee Alhalabi, Marta Rosenberg, Walter J Meyer, Marsha M Linehan
Sustaining a burn injury increases an individual's risk of developing psychological problems such as generalized anxiety, negative emotions, depression, acute stress disorder, or post-traumatic stress disorder. Despite the growing use of Dialectical Behavioral Therapy® (DBT®) by clinical psychologists, to date, there are no published studies using standard DBT® or DBT® skills learning for severe burn patients. The current study explored the feasibility and clinical potential of using Immersive Virtual Reality (VR) enhanced DBT® mindfulness skills training to reduce negative emotions and increase positive emotions of a patient with severe burn injuries...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28993227/adverse-glycaemic-effects-of-cancer-therapy-indications-for-a-rational-approach-to-cancer-patients-with-diabetes
#20
REVIEW
Marco Gallo, Giovanna Muscogiuri, Francesco Felicetti, Antongiulio Faggiano, Francesco Trimarchi, Emanuela Arvat, Riccardo Vigneri, Annamaria Colao
Diabetes and cancer are common, chronic, and potentially fatal diseases that frequently co-exist. Observational studies have reported an increased risk of cancer in patients with diabetes. Furthermore, many patients with cancer already have diabetes, or develop hyperglycemia as a consequence of the tumor or of cancer therapies, and coexisting diabetes confers a greater risk of mortality for many malignancies. Managing oncologic patients with diabetes is often complicated, since the co-existence of diabetes and cancer poses several complex clinical questions: what level of glycemic control to achieve, which therapy to use, how to deal with glucocorticoid therapies and artificial nutrition, how diabetes complications can affect cancer management, which drug-drug interactions should be taken into account, or even how to manage diabetes at the end of life...
October 6, 2017: Metabolism: Clinical and Experimental
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