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laser cordectomy

Andy Bertolin, Marco Lionello, Gianni Salis, Giuseppe Rizzotto, Marco Lucioni
PURPOSE: The aim of the present paper was to investigate the oncological safety of two-stage bilateral cordectomy for the treatment of cT1b glottic SCC, and to compare its oncological outcome and synechia development rate with those of single-stage procedures. MATERIALS AND METHODS: A retrospective cohort study was performed at the Otolaryngology Unit of Vittorio Veneto Laryngeal Cancer Center (Italy). The prognostic significance of clinical, pathological and surgical factors was also investigated, in terms of recurrence rate and disease-free survival, in a univariate statistical setting...
March 2017: American Journal of Otolaryngology
Vincenzo Landolfo, Carmine Fernando Gervasio, Giuseppe Riva, Massimiliano Garzaro, Rita Audisio, Giancarlo Pecorari, Roberto Albera
INTRODUCTION: Cordectomy by laringofissure and transoral laser surgery has been proposed for the treatment of early glottic cancer. OBJECTIVES: The aim of this retrospective study was to evaluate the prognostic value of margin status in 162 consecutive cases of early glottic carcinoma (Tis-T1) treated with CO2 laser endoscopic surgery (Group A) or laryngofissure cordectomy (Group B), and to compare the oncologic and functional results. METHODS: Clinical prognostic factors, local recurrence rate according to margin status, overall survival and disease-free survival were analyzed...
December 24, 2016: Brazilian Journal of Otorhinolaryngology
Young Ju Jin, Woo-Jin Jeong, Jin Ho Paik, Soon-Hyun Ahn
Frozen biopsies are frequently used for decision making during surgery. This study aimed to evaluate the efficacy of frozen biopsy for guiding decision making before laser excision of glottic premalignant lesions. One hundred patients with 119 laser excisions were included in this study and reviewed retrospectively. After frozen biopsy, type I or II cordectomy was performed and the frozen result and final pathology of the excisional specimen were compared. The positive predictive value of frozen biopsy when the diagnosis is benign or malignant was relatively high (80...
November 5, 2016: Pathology Oncology Research: POR
Lucille Wallet
This article deals with the intelligibility of stop consonants in onset position (initial and intervocalic) as pronounced by 10 French speakers treated by a type II or III cordectomy. These surgeries cause a less efficient glottal closure and a vibratory asymmetry. The voicing contrast in consonants may be altered. The patients' vocal samples were made up of non-words of the CVCVCVC type, where C = /p, t, k, b, d, g/ and V = /a, i, u/(n = 360), and were given to 22 French listeners for evaluation. Two identification tests were created and the listeners were asked to choose the consonants they thought they recognized (n = 7920)...
2017: Clinical Linguistics & Phonetics
Azman Mawaddah, Mat Baki Marina, Sawali Halimuddin, Mohd Yunus Mohd Razif, Sani Abdullah
Bilateral vocal fold immobility (BVFI) is commonly caused by injury to the recurrent laryngeal nerve (RLN) and leads to stridor and dyspnea of varying onsets. A retrospective study was done at the Department of Otorhinolaryngology of Universiti Kebangsaan Malaysia Medical Centre on laser microsurgical posterior cordectomy for BVFI. The objectives were to identify the average duration of onset of stridor from the time of insult and to evaluate the outcome of laser posterior cordectomy as a surgical option. From 1997 to 2007, a total of 31 patients with BVFI were referred for surgery...
July 2016: Malaysian Journal of Medical Sciences: MJMS
Kazuo Adachi, Toshiro Umezaki, Toshimitsu Nishijima, Hidetaka Yamamoto, Yoshinao Oda
Here we describe the long-term outcomes of type I thyroplasty (TP-I) with silicone block implantation through histopathological assessments in a male patient who underwent pharyngolaryngectomy for secondary hypopharyngeal carcinoma 7 years after silicone implantation. A 66-year-old man presented with esophageal carcinoma and underwent subtotal esophagotomy. Subsequently, his left vocal fold exhibited fixation in a paramedian position, and he underwent TP-I with silicone block implantation 2 years after the primary esophageal surgery...
April 2017: Auris, Nasus, Larynx
Mohssen Ansarin, Augusto Cattaneo, Luigi De Benedetto, Stefano Zorzi, Francesca Lombardi, Daniela Alterio, Maria Cossu Rocca, Daniele Scelsi, Lorenzo Preda, Fausto Chiesa, Luigi Santoro
BACKGROUND: The purpose of this study was to identify the factors influencing oncologic outcomes for patients with early-intermediate glottic cancer treated by transoral laser microsurgery (TLM). METHODS: This was a retrospective mono-institutional study. A total of 590 patients with cTis-cT3 glottic cancer underwent TLM with curative intent. RESULTS: TLM alone was performed in 538 patients (91.2%) and TLM followed by adjuvant radiotherapy (RT) was done in 52 (8...
January 2017: Head & Neck
Quentin Charbonnier, Anne-Sophie Thisse, Laurent Sleghem, François Mouawad, Dominique Chevalier, Cyril Page, Geoffrey Mortuaire
BACKGROUND: The oncologic impact of surgical margins after transoral laser microsurgery (TLM) for T1 and T2 glottic carcinoma is controversial. The purpose of this study was to assess the prognostic value of margin status in terms of local control. METHODS: Records of 266 patients treated from 1990 to 2013 were evaluated. Patients with previous cordectomy or without preoperative CT scan were excluded from the study. RESULTS: A total 110 patients (85 T1a, 8 T1b, and 17 T2) were enrolled...
December 2016: Head & Neck
A Galli, L Giordano, D Sarandria, D Di Santo, M Bussi
Several therapeutic options are used for treatment of early stage glottic carcinoma (Tis/T1/T2): open partial laryngectomy (OPL), radiotherapy and CO2 laser-assisted endoscopic surgery. Laser surgery has gradually gained approval in the management of laryngeal cancer. We present our experience in endoscopic laser surgery for early stage glottic carcinomas. This was a retrospective analysis of 72 patients with T1-T2 glottic cancer treated with laser cordectomy between 2006 and 2012. All patients had at least a 36-month follow-up period...
June 2016: Acta Otorhinolaryngologica Italica
P D Karkos, S Dova, S Sotiriou, K Markou, I Kostopoulos
ΒACKGROUND: Synchronous multiple malignancies of the larynx are rare. We present a case here of synchronous primary laryngeal squamous cell carcinoma (SCC) and malignant fibrous histiocytoma (MFH) in a patient with hoarseness though with no history of exposure to radiation. Clinical, intraoperative, and histopathological findings in this patient are discussed. METHODS: Wide laser excision of the left supraglottic lesion and laser cordectomy of the right true vocal cord were performed...
2016: Ecancermedicalscience
Hani Osama Nasef, Hossam Thabet, Cesare Piazza, Francesca Del Bon, Mohamed Eid, Manal El Banna, Piero Nicolai
56 patients affected by T2 glottic carcinoma were treated in two institutes using transoral laser microsurgery (TLM) in 40 cases and vertical hemilaryngectomy in 16 cases between September 2012 and September 2015. In the TLM group, different subtypes of type V cordectomy were used according to the extent of tumor. In the vertical hemilaryngectomy group, classical operation was used in most of the cases and the resection was extended in few cases. Analysis of post-operative swallowing function was done using videofluoroscopy (VFS), functional endoscopic evaluation of swallowing, and subjectively using MD Anderson dysphagia inventory...
August 2016: European Archives of Oto-rhino-laryngology
Takeyuki Kono, Koichiro Saito, Haruna Yabe, Kaoru Ogawa
OBJECTIVES/HYPOTHESIS: This study was designed to assess the feasibility of the submucosal infusion technique combined with microflap dissection as a radical therapeutic and diagnostic option for precancerous laryngeal leukoplakia. STUDY DESIGN: Retrospective study. METHODS: Severe dysplasia or carcinoma in situ was diagnosed after phonomicrosurgical dissections in 25 patients with unilateral laryngeal leukoplakia. Of these, 15 patients preferred no additional surgery (observation group), whereas 10 patients underwent further laser subligamental cordectomy (additional surgery group)...
January 2017: Laryngoscope
Q Wang, L Xu, W B Wang, H L Wang, H Yuan, Y Ling, L Shen, G K Fan
OBJECTIVE: To study the wound healing following CO2 laser microsurgery for early glottic cancer, and to evaluate the treatment outcomes and cost-effectiveness of microsurgery, open surgery and radiotherapy for early glottic cancer. METHODS: Thirty-six patients with early glottic carcinoma (T1-T2) treated by transoral CO2 laser microsurgery from January 2011 to June 2014 were observed, and 112 patients undergoing open approach and 27 receiving radiotherapy from January 2008 to June 2014 in our hospital were used as control...
April 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Takeyuki Kono, Koichiro Saito, Haruna Yabe, Kosuke Uno, Kaoru Ogawa
BACKGROUND: This study was designed to comparatively assess laryngeal function and quality of life (QOL) of patients after laser surgery (LS) or radiotherapy (RT) for early glottic cancer. METHODS: Sixty-four patients with T1 glottic cancer treated with RT or type II cordectomy underwent both subjective and objective vocal assessments. The LS group was divided into the following: (1) vaporization with defocused mode (laser surgery [LS]-Vap); and (2) excision with focused mode using lower power (LS-Ex)...
July 2016: Head & Neck
Hyoung Shin Lee, Ji Su Kim, Sung Won Kim, Woong Jae Noh, Young Joon Kim, Dasol Oh, Jong Chul Hong, Kang Dae Lee
OBJECTIVES/HYPOTHESIS: To evaluate the outcomes of transoral laser microsurgery (TLM) for T1 glottic carcinoma using longitudinal voice analysis. STUDY DESIGN: Retrospective analysis of medical records. METHODS: We conducted a retrospective review of 57 patients (50 T1a, seven T1b) who underwent TLM for T1 glottic carcinoma, and longitudinal voice analysis was performed before surgery, during the early postoperative period (within 3 months), and during the late postoperative period (more than 6 months)...
September 2016: Laryngoscope
Lei Shen, Lin Xu, Qi Wang, Guo-Kang Fan
BACKGROUND AND OBJECTIVE: Transoral laser surgery is useful for treating early glottic carcinoma. Wound areas after carbon dioxide (CO2 ) laser surgery are not covered by flaps, delaying healing. The healing process following laser cordectomy is not well understood. In this study, laryngoscopes were used to monitor the normal healing process after laser cordectomy and to determine if there was residual or recurrent disease. MATERIALS AND METHODS: This prospective case study included 36 patients who underwent CO2 laser surgery for early glottis carcinoma between January 2011 and June 2014 at a university tertiary referral center...
July 2016: Lasers in Surgery and Medicine
Zakaria Soliman, Sameh Mohammad Hosny, Mohammad Waheed El-Anwar, Amal Saeed Quriba
OBJECTIVES: Carbon dioxide (CO2) laser cordectomy is considered one of the modalities of choice for treatment of early glottic carcinoma. In addition to its comparable oncological results with radiotherapy and open surgical procedures, it preserves of laryngeal functions including voice production. The aim of this study was to detect how the larynx compensates for voice production after different types of CO2 laser cordectomy for early glottic carcinoma together with assessment of the vocal outcome in each compensation mechanism...
December 2015: Clinical and Experimental Otorhinolaryngology
Caroline Hoffmann, Nicolas Cornu, Stéphane Hans, Babak Sadoughi, Cécile Badoual, Daniel Brasnu
OBJECTIVES/HYPOTHESIS: Anterior commissure involvement is considered to be a risk factor for poorer outcomes after transoral laser cordectomy (TLC) for early glottic cancer. The objective of this study was to determine the outcomes and relevance of the tumor-node-metastasis (TNM) classification in a large series of patients with early glottic cancer involving the anterior commissure treated by TLC. METHODS: The clinical and surgical parameters, as well as follow-up results, of the patients treated consecutively for early-stage glottic squamous cell carcinoma involving the anterior commissure (Tis, T1a, T1b, and T2) by transoral CO2 laser cordectomy in an urban academic medical center from January 2001 to March 2013 were analyzed retrospectively...
August 2016: Laryngoscope
Grazyna Lisowska, Pawel Sowa, Hanna Misiolek, Wojciech Scierski, Maciej Misiolek
INTRODUCTION: Surgery of the thyroid gland remains the main cause of bilateral vocal cord palsy (VCP). Ventilation problem is the main problem in such situations. There are a couple of corrective surgical procedures in the case of VCP. The aim of our study was to show the possibility of widening of the glottis, and to evaluate the techniques and effects of surgical treatments due to bilateral VCP resulting from thyroid gland surgery. MATERIAL AND METHODS: Five methods of surgical treatment were used: laser-assisted posterior cordectomy, according to Denis and Kashima; laser-assisted bilateral medial arytenoidectomy, as proposed by Crumley; laser-assisted posterior ventriculocordectomy, as described by Pia; laser-assisted total arytenoidectomy with posterior cordectomy, as presented by Ossoff; and laterofixation, according to Lichtenberger...
2015: Endokrynologia Polska
Marco Lucioni, Andy Bertolin, Marco Lionello, Luciano Giacomelli, Giuseppe Rizzotto, Gino Marioni
Total laryngectomy (TL) is often still recommended as a salvage approach for recurrent laryngeal squamous cell carcinoma (LSCC). Considering LSCC recurrences after the failure of primary transoral laser microsurgery (TLM), open partial horizontal laryngectomy (OPHL) could be a valid alternative to TL in selected patients. The aim of the present study was to analyze retrospectively the oncological outcome of a consecutive series of 17 patients treated at the Otolaryngology Unit of Vittorio Veneto Hospital (Italy) with OPHL after primary TLM had failed...
January 2016: European Archives of Oto-rhino-laryngology
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