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Psychopharmacology

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https://www.readbyqxmd.com/read/27933099/treating-nonsuicidal-self-injury-nssi-in-adolescents-consensus-based-german-guidelines
#1
Paul L Plener, Romuald Brunner, Jörg M Fegert, Rebecca C Groschwitz, Tina In-Albon, Michael Kaess, Nestor D Kapusta, Franz Resch, Katja Becker
BACKGROUND: Nonsuicidal self-injury (NSSI) is a frequent and clinically relevant phenomenon in adolescence. Within Europe, Germany has one of the highest prevalence rates in youth with lifetime prevalence ranging between 25 and 35%. However, treatment guidelines for NSSI are not yet available. METHODS: Consensus based clinical guidelines were created by a working group consisting of members of eleven medical, psychological or psychotherapeutic professional national associations, and two members of patient self-help and prevention groups...
2016: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/27906413/comparison-of-psychodrug-prescription-patterns-in-patients-diagnosed-with-bipolar-disorder-and-addiction
#2
Diego Barral, Fátima Barral, Nuria Cruz, Juan D Molina, Victoria Sánchez, Teresa Rosique
OBJECTIVE: To describe if there are differences in the prescription of psychodrug at discharge between bipolar disorder patients with or without addiction. METHODS: We review all the psychotropic drugs dispensed to inpatients of a brief hospitalization psychiatric unit diagnosed as having bipolar disorder at time of discharge. We recluted 225 patients over 18 years old on their last manic episode, between the year 2000 and 2010. We classify them according to the comorbid presence or not of a substance abuse or dependence disorder...
November 2016: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/27901342/correction-to-journal-of-child-and-adolescent-psychopharmacology-2015-25-738-748
#3
(no author information available yet)
No abstract text is available yet for this article.
November 30, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27899087/paradoxical-physiological-responses-to-propranolol-in-a-rett-syndrome-patient-a-case-report
#4
P J Santosh, L Bell, K Lievesley, J Singh, F Fiori
BACKGROUND: Rett Syndrome (RTT), caused by a loss-of-function in the epigenetic modulator: X-linked methyl-CpG binding protein 2 (MeCP2), is a pervasive neurological disorder characterized by compromised brain functions, anxiety, severe mental retardation, language and learning disabilities, repetitive stereotyped hand movements and developmental regression. An imbalance in the sympathetic and the parasympathetic nervous system (dysautonomia) and the resulting autonomic storms is a frequent occurrence in patients with RTT...
November 29, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27894241/a-novel-relationship-for-schizophrenia-bipolar-and-major-depressive-disorder-part-6-a-hint-from-chromosome-6-high-density-association-screen
#5
X Chen, F Long, B Cai, X Chen, G Chen
Convergent evidence from genetics, symptomatology and psychopharmacology imply that there are intrinsic connections between schizophrenia (SCZ), bipolar disorder (BPD) and major depressive disorder (MDD), for example, any two or even three of these disorders could co-exist in some families. A total of 56.400 single nucleotide polymorphism (SNPs) on chromosome 6 were genotyped by Affymetrix Genome-Wide Human SNP array 6.0 on 119 SCZ, 253 BPD (type-I), 177 MDD patients and 1000 controls. Associated SNP loci on chromosome 6 were comprehensively revealed and outstanding susceptibility genes were identified including JARID2 (Homo sapiens jumonji, AT rich interactive domain 2) which plays an essential role in embryonic development and neural tube fusion process...
November 28, 2016: Current Molecular Medicine
https://www.readbyqxmd.com/read/27891052/from-ethanol-to-salsolinol-role-of-ethanol-metabolites-in-the-effects-of-ethanol
#6
REVIEW
Alessandra T Peana, Michela Rosas, Simona Porru, Elio Acquas
In spite of the global reputation of ethanol as the psychopharmacologically active ingredient of alcoholic drinks, the neurobiological basis of the central effects of ethanol still presents some dark sides due to a number of unanswered questions related to both its precise mechanism of action and its metabolism. Accordingly, ethanol represents the interesting example of a compound whose actions cannot be explained as simply due to the involvement of a single receptor/neurotransmitter, a scenario further complicated by the robust evidence that two main metabolites, acetaldehyde and salsolinol, exert many effects similar to those of their parent compound...
2016: Journal of Experimental Neuroscience
https://www.readbyqxmd.com/read/27878918/survey-of-antipsychotic-medication-curriculum-content-in-australian-university-nursing-programmes
#7
Paul Morrison, Norman J Stomski, Margaret McAllister, Dianne Wynaden, Catherine Hungerford, Kim Usher, Phil Maude, Andrew Crowther, Robert Batterbee
Antipsychotic medication has long been one of the first-line interventions for people with serious mental illness, with outcomes including reductions in symptoms and relapse rates. More recently, however, questions have been raised about the efficacy of antipsychotic medications, especially in light of their side-effect profile. Such questions have implications for the nurses administering antipsychotic medications, particularly in relation to their knowledge of the antipsychotic medication, its efficacy, and side-effect profile...
November 23, 2016: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/27872001/psychosocial-approaches-for-sexual-health-and-intimate-relationships-among-patients-with-serious-mental-illness
#8
REVIEW
Paula Helu-Brown, Maria Aranda
INTRODUCTION: The sexual health and behavior and the intimate relationships of patients diagnosed with a serious mental illness (SMI) have been described as ongoing and often ignored concerns in mental health treatment. Evidence-based psychosocial interventions have emerged as effective complimentary approaches to address symptoms of SMI in conjunction with psychopharmacology, yet rarely do they address sexual concerns in a targeted manner. AIM: This systematic review explores the scope and efficacy of psychosocial interventions designed to address sexual health and behavior and intimate relationship concerns in patients with SMI...
January 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27855728/dextromethorphan-quinidine-responsive-pseudobulbar-affect-pba-psychopharmacological-model-for-wide-ranging-disorders-of-emotional-expression
#9
Stephen M Stahl
The symptoms of emotional dysregulation associated with the syndrome known as pseudobulbar affect (PBA) can be effectively treated by the sigma, glutamate, and serotonergic agent dextromethorphan combined with quinidine. If the same brain circuits affected in PBA are also compromised in related disorders of emotional expression, dextromethorphan-quinidine and other novel sigma-glutamate-serotonin agents could prove to be novel psychopharmacologic treatments for these conditions as well.
December 2016: CNS Spectrums
https://www.readbyqxmd.com/read/27855437/the-relevance-of-negative-symptoms-in-schizophrenia-and-how-to-treat-them-with-psychopharmaceuticals
#10
Hans-Jürgen Möller
Negative symptoms are highly prevalent in the acute episode and long-term course of schizophrenia. They are often persistent and tend to chronicity. They have an important negative impact on different dimensions of outcome and therefore require careful diagnosis and treatment. However, the evidence for the available psychopharmacological treatments is still not satisfactory and further research is needed. Antipsychotics, especially some second-generation antipsychotics, are the primary treatment of choice, particularly for negative symptoms in the acute episode...
December 2016: Psychiatria Danubina
https://www.readbyqxmd.com/read/27852960/set-and-setting-psychedelics-and-the-placebo-response-an-extra-pharmacological-perspective-on-psychopharmacology
#11
REVIEW
Ido Hartogsohn
Placebo response theory and set and setting theory are two fields which examine how non-biological factors shape the response to therapy. Both consider factors such as expectancy, preparation and beliefs to be crucial for understanding the extra-pharmacological processes which shape the response to drugs. Yet there are also fundamental differences between the two theories. Set and setting concerns itself with response to psychoactive drugs only; placebo theory relates to all therapeutic interventions. Placebo theory is aimed at medical professionals; set and setting theory is aimed at professionals and drug users alike...
December 2016: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/27845315/-agomelatine-valdoxan-in-treatment-of-endogenous-depression-in-day-patient-department
#12
E V Chernova, O V Kozhechkina, A Yu Ter-Israelyan, V E Medvedev
AIM: Naturalistic psychopharmacological study of efficacy and tolerability of agomelatine (valdoxan) in treatment of endogenous depressions (in the framework of schizophrenia, schizoaffective and bipolar disorder) in day patient department. MATERIAL AND METHODS: Study sample consisted of 37 patient (59.4% female, mean age 41.6±3.7 years). RESULTS AND CONCLUSION: CDS total score significantly reduced after 8 weeks of treatment 44.9% compared to baseline (р<0...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/27836150/psychopharmacology-of-persistent-violence-and-aggression
#13
REVIEW
Jonathan M Meyer, Michael A Cummings, George Proctor, Stephen M Stahl
Persistent violence not due to acute psychosis or mania can be managed only after appropriate characterization of the aggressive episodes (psychotic, impulsive, or predatory/planned/instrumental). The type of violence combined with the psychiatric diagnosis dictates the evidence-based pharmacologic approaches for psychotically motivated and impulsive aggression, whereas instrumental violence mandates forensic/behavioral strategies. For nonacute inpatients, schizophrenia spectrum disorders, traumatic brain injury, and dementia comprise the majority of individuals who are persistently aggressive, with impulsive actions the most common form of violence across all diagnoses...
December 2016: Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/27834755/thirty-years-of-journal-of-psychopharmacology
#14
EDITORIAL
David J Nutt
No abstract text is available yet for this article.
November 2016: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/27833894/comparison-of-the-effects-of-methylphenidate-and-the-combination-of-methylphenidate-and-risperidone-in-preschool-children-with-attention-deficit-hyperactivity-disorder
#15
Parvin Safavi, Ali Hasanpour Dehkordi, Nasim Ghasemi
Attention-deficit hyperactivity disorder (ADHD) is a common psychiatric disorder among preschool children but the number of controlled clinical trials regarding psychopharmacological treatment in this age group is limited. The aim of this study was to compare methylphenidate with the combination of methylphenidate and risperidone in preschool children with ADHD. Forty-two preschool children, aged 3-6 years, diagnosed with ADHD by a child and adolescent psychiatrist according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition-Text Revision criteria, were enrolled in a 6-week, single-blind clinical trial and administered with methylphenidate (5-30 mg/dl) or the combination of methylphenidate and risperidone (0...
October 2016: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/27832676/editorial-to-child-and-adolescence-psychopharmacology
#16
G Juckel
The editors of Pharmacopsychiatry have decided in 2016 to prepare special issues regularly in order provide our readers volumes of the journal with a thematic focus 1. The first such special issue is dedicated to the field of child and adolescent psychopharmacology. Many young patients are treated with psychotherapeutic, but also pharmacotherapeutic, methods worldwide. Most of our psychopharmacological agents are not approved by the federal institutions for persons under 18 years old. However, severe mental illnesses like schizophrenia, depression, anxiety, ADHD, and bipolar disorder frequently require pharmacological treatments in children and adolescents...
November 2016: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27824311/-unmet-needs-in-the-recognition-and-treatment-of-childhood-depression
#17
Sandor Kalmar
In spite of the fact that the good mental health is indispensable condition of the development of sound personality, in the past years the somatic and mental state of our children did not improve. The author ascertains that there are several obstacles in the recognition, treatment and prevention of child-depression that causes a serious public health problem. He stresses the neurologic, neuropsychiatric, psychopathological and diagnostic deficiencies, and the low number of Child and Youth Dispensaries. He describes the situation of Hungarian Child and Youth Dispensaries network, and states positively that today the child-psychiatric services are not able to provide optimal provision for every depressive child...
September 2016: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/27816941/the-international-college-of-neuro-psychopharmacology-cinp-treatment-guidelines-for-bipolar-disorder-in-adults-cinp-bd-2017-part-2-review-grading-of-the-evidence-and-a-precise-algorithm
#18
REVIEW
Konstantinos N Fountoulakis, Lakshmi Yatham, Heinz Grunze, Eduard Vieta, Allan Young, Pierre Blier, Siegfried Kasper, Hans Jurgen Moeller
BACKGROUND: The current paper includes the systematic search of the literature, the detailed presentation of the results and the grading of treatment options in terms of efficacy and tolerability/safety. MATERIAL AND METHODS: The PRISMA method was used in the search of the literature with the combination of the words 'bipolar', 'manic', 'mania', 'manic depression' and 'manic depressive' with 'randomized', and 'algorithms' with 'mania', 'manic', 'bipolar', 'manic-depressive' or 'manic depression'...
November 5, 2016: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27816317/pharmacological-treatment-strategies-in-unipolar-depression-in-european-tertiary-psychiatric-treatment-centers-a-pharmacoepidemiological-cross-sectional-multicenter-study
#19
Markus Dold, Alexander Kautzky, Lucie Bartova, Ulrich Rabl, Daniel Souery, Julien Mendlewicz, Stefano Porcelli, Alessandro Serretti, Joseph Zohar, Stuart Montgomery, Siegfried Kasper
This multicenter, cross-sectional study with retrospective assessment of treatment response evaluated the current prescription trends and pharmacological treatment strategies applied in European university/academic psychiatric centers in unipolar depression. Altogether, 1181 adult in- and outpatients with major depressive disorder (MDD) were enrolled in 9 academic sites in 8 European countries. Socio-demographic, clinical, and medication information were retrieved and the present symptom severity was assessed by the Montgomery and Åsberg Depression Rating Scale (MADRS)...
December 2016: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27794561/assessment-of-depression-and-suicidal-behaviour-among-medical-students-in-portugal
#20
Ricardo Coentre, Carlo Faravelli, Maria Luísa Figueira
Objectives: To examine depression and suicidal behaviour and associated factors in a sample of medical students in Portugal. Methods: We conducted a cross-sectional study design of 456 native Portuguese medical students from the 4(th) and 5(th) year at the University of Lisbon. Participants answered a self-report survey including questions on demographic and clinical variables. Statistical analyses were conducted using the chi-square test, with a Monte Carlo simulation when appropriate...
October 29, 2016: International Journal of Medical Education
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