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Ozone injection

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https://www.readbyqxmd.com/read/28925753/ozone-partially-decreases-axonal-and-myelin-damage-in-an-experimental-sciatic-nerve-injury-model
#1
Zahir Kızılay, Nesibe Kahraman Çetin, Mehran Aksel, Burçin İrem Abas, Serdar Aktaş, Haydar Ali Erken, Abdullah Topçu, Ali Yılmaz, Cigdem Yenisey
AIM: To investigate the effects of ozone in experimental acute sciatic nerve injury. MATERIAL AND METHODS: Twenty-eight male rats were divided into four groups (n = 7): control (C), ozone (O), injury (SNI), and treatment with ozone after injury (SNI + Ozone). Sciatic nerve injury was generated by compressing the right sciatic nerve for 90 s using a Yasargil aneurysm clip in groups SNI and SNI + Ozone. A 70 µg/ml concentration of ozone was given four times (once a day at 1st, 24th, 48th, and 72th h) at a dose of 0...
September 19, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28911970/mesenchymal-stem-cells-alleviate-oxidative-stress-induced-mitochondrial-dysfunction-in-the-airways
#2
Xiang Li, Charalambos Michaeloudes, Yuelin Zhang, Coen H Wiegman, Ian M Adcock, Qizhou Lian, Judith C W Mak, Pankaj K Bhavsar, Kian Fan Chung
BACKGROUND: Oxidative stress-induced mitochondrial dysfunction may contribute to inflammation and remodeling in chronic obstructive pulmonary disease (COPD). Mesenchymal stem cells (MSCs) protect against lung damage in animal models of COPD. It is unknown whether these effects occur through attenuating mitochondrial dysfunction in airway cells. OBJECTIVE: To examine the effect of induced-pluripotent stem cell-derived MSCs (iPSC-MSCs) on oxidative stress-induce mitochondrial dysfunction in human airway smooth muscle cells (ASMCs) in vitro and in mouse lungs in vivo...
September 11, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28910071/a-simple-incl3-doped-pedot-pss-and-uv-ozone-treatment-strategy-external-quantum-efficiency-up-to-21-for-solution-processed-organic-light-emitting-devices-with-a-thermally-activated-delayed-fluorescence-emitter
#3
Tao Zhou, Guohua Xie, Shaolong Gong, Manli Huang, Jiajia Luo, Chuluo Yang
A low-cost and easy-processed scheme for solution processed organic light-emitting devices (OLEDs) was provided to overcome the flaws of poly(styrene sulfonic acid)-doped poly(3,4-ethylenedioxythiphene) (PEDOT:PSS) together with the indium tin oxide (ITO) anode. The modified PEDOT:PSS with higher work function (5.66 eV), higher conductivity and more efficient hole injecting ability was obtained by simply mixing the aqueous PEDOT:PSS with InCl3 and then consecutive ultraviolet-ozone treatment. The simply structured and solution-processed OLEDs with our modified PEDOT:PSS achieved very high external quantum efficiency of 21...
September 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28886552/removal-of-napl-from-columns-by-oxidation-sparging-surfactant-and-thermal-treatment
#4
F Jousse, O Atteia, P Höhener, G Cohen
In this paper, four treatment techniques commonly applied to Volatile Organic Compounds (VOC) removal from soil are compared in column experiments with pure sand containing a residual Light Non-Aqueous Phase Liquid (L-NAPL) contamination. Oxidation is tested through the injection of Fenton reagent, with persulfate, and combined with sparging with the injection of ozone. Surfactant treatment was conducted at low flow rates with Tween(®)80. Sparging was conducted by air injection but at a low flow rate of 1 mL min(-1)...
September 1, 2017: Chemosphere
https://www.readbyqxmd.com/read/28886142/effects-of-ozone-exposure-on-human-epithelial-adenocarcinoma-and-normal-fibroblasts-cells
#5
Anna Poma, Sabrina Colafarina, Eleonora Aruffo, Osvaldo Zarivi, Antonella Bonfigli, Sebastiano Di Bucchianico, Piero Di Carlo
Previous studies show variable ozone cytotoxicity and genotoxicity in cell cultures, laboratory animals and humans directly exposed to tropospheric ozone. The aim of this study was therefore to investigate and compare the cyto and genotoxic effects of ozone using adenocarcinoma human alveolar basal epithelial cells A549 and normal human fibroblasts Hs27. A cell culture chamber with controlled atmosphere (a simulation reactor) was built to inject a flow of 120 ppb of ozone, which is two times the threshold value for the protection of human health, fixed by the EU legislation...
2017: PloS One
https://www.readbyqxmd.com/read/28827324/on-transient-climate-change-at-the-cretaceous-paleogene-boundary-due-to-atmospheric-soot-injections
#6
Charles G Bardeen, Rolando R Garcia, Owen B Toon, Andrew J Conley
Climate simulations that consider injection into the atmosphere of 15,000 Tg of soot, the amount estimated to be present at the Cretaceous-Paleogene boundary, produce what might have been one of the largest episodes of transient climate change in Earth history. The observed soot is believed to originate from global wildfires ignited after the impact of a 10-km-diameter asteroid on the Yucatán Peninsula 66 million y ago. Following injection into the atmosphere, the soot is heated by sunlight and lofted to great heights, resulting in a worldwide soot aerosol layer that lasts several years...
August 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28815790/evaluation-of-wastewater-treatment-by-ozonation-for-reducing-the-toxicity-of-contaminants-of-emerging-concern-to-rainbow-trout-oncorhynchus-mykiss
#7
Nicholas Maya, Jaden Evans, Deniz Nasuhoglu, Siavash Isazadeh, Viviane Yargeau, Chris D Metcalfe
While conventional wastewater treatment technologies are effective at removing many contaminants of emerging concern (CECs) from municipal wastewater, some contaminants are not removed efficiently. Ozonation may be a treatment option for reducing the concentrations of recalcitrant CECs in wastewater, but this process may generate toxic transformation-products. In the present study, we conducted semi-batch experiments to ozonate municipal wastewater effluent (WWE) spiked with 5 commonly detected CECs. The purpose of the study was to evaluate whether ozonation increased or decreased biological responses indicative of sublethal toxicity in juvenile rainbow trout (Oncorhynchus mykiss) injected intraperitoneally (i...
August 16, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28807098/protective-effect-of-ozone-against-hemiscorpius-lepturus-envenomation-in-mice
#8
Parvaneh Naserzadeh, Farshad Shahi, Delavar Shahbazzadeh, Mostafa Ghanei, Khadijeh Ashtari, Yoones Panahi, Mir-Jamal Hosseini, Morteza Izadi
OBJECTIVE: Scorpion (Hemiscorpius lepturus) stings are a public health concern in Iran, particularly in south and southwestern regions of Iran. The gold standard for the treatment of a scorpion sting is anti-venom therapy. However, immunotherapy can have serious side effects, such as anaphylactic shock (which can sometimes even lead to death). The aim of the current study was to demonstrate the protective effect of ozone against toxicity induced by Hemiscorpius lepturus (H. lepturus) venom in mice...
August 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28759792/dual-starch-polyacrylamide-polymer-system-for-improved-flocculation
#9
Mathieu Lapointe, Benoit Barbeau
Organic polyelectrolytes such as polyacrylamide (PAM) are commonly used in the water industry to improve flocculation. However, potential adverse health effects may arise from the use of PAM owing to the presence of trace acrylamide monomers in commercial products. Hence, there is growing interest in replacing synthetic polyelectrolytes with natural and sustainable alternatives, which would eliminate risks related to the presence of toxic monomers/impurities and oxidation by-products from the interaction of polymers and common disinfectants such chlorine and ozone...
July 24, 2017: Water Research
https://www.readbyqxmd.com/read/28738079/comparison-between-intra-articular-ozone-and-placebo-in-the-treatment-of-knee-osteoarthritis-a-randomized-double-blinded-placebo-controlled-study
#10
Carlos César Lopes de Jesus, Fânia Cristina Dos Santos, Luciana Maria Oliveira Bueno de Jesus, Iara Monteiro, Maria Sonia Sousa Castro Sant'Ana, Virginia Fernandes Moça Trevisani
OBJECTIVE: The aim of the trial was to determine the effectiveness of oxygen-ozone injections on knee osteoarthritis concerning pain reduction, joint functional improvement, and quality of life. METHODS: In this randomized, double-blinded, placebo controlled clinical trial, 98 patients with symptomatic knee osteoarthritis (OA) were randomized into two groups receiving intra-articular 20 μg/ml of ozone (OZ) or placebo (PBO) for 8 weeks. The efficacy outcomes for knee OA were the Visual Analogue Scale (VAS), Lequesne Index, Timed Up and Go Test (TUG Test), SF-36, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Geriatric Pain Measure (GPM)...
2017: PloS One
https://www.readbyqxmd.com/read/28727712/intervertebral-foramen-injection-of-ozone-relieves-mechanical-allodynia-and-enhances-analgesic-effect-of-gabapentin-in-animal-model-of-neuropathic-pain
#11
Wen-Jun Luo, Fan Yang, Fei Yang, Wei Sun, Wei Zheng, Xiao-Liang Wang, Fang-Fang Wu, Jiang-Lin Wang, Jia-Shuang Wang, Su-Min Guan, Jun Chen
BACKGROUND: In a 5-year follow-up study in a hospital in southern China, it was shown that intervertebral foramen (IVF) injection of ozone at the involved segmental levels could significantly alleviate paroxysmal spontaneous pain and mechanical allodynia in patients with chronic, intractable postherpetic neuralgia (PHN) and improve the quality of life. However, so far no proof-of-concept studies in animals have been available. OBJECTIVE: This study was designed to investigate whether IVF ozone has an analgesic effect on animal models of neuropathic and inflammatory pain...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28727368/medical-ozone-therapy-reduces-oxidative-stress-and-testicular-damage-in-an-experimental-model-of-testicular-torsion-in-rats
#12
Mustafa Tusat, Ahmet Mentese, Selim Demir, Ahmet Alver, Mustafa Imamoglu
OBJECTIVE: Testicular torsion (TT) refers to rotation of the testis and twisting of the spermatic cord. TT results in ischemia-reperfusion (I/R) injury involving increased oxidative stress, inflammation and apoptosis, and can even lead to infertility. The aim of this study was to investigate the effect of ozone therapy on testicular damage due to I/R injury in an experimental torsion model. MATERIALS AND METHODS: 24 male Sprague-Dawley rats were divided into 3 groups; sham-operated, torsion/detorsion (T/D), and T/D+ozone...
June 14, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28614539/effects-of-ozone-on-the-pain-and-disability-in-patients-with-failed-back-surgery-syndrome
#13
Danilo Costa Barbosa, Jairo Silva Dos Ângelos, Gleica Maria Josino de Macena, Francisco Nêuton de Oliveira Magalhães, Erich Talamoni Fonoff
Introduction: Low back pain is one of the painful disorders of higher prevalence. It has several etiologies and surgery may be indicated in the presence of neurological deficits or compression syndromes. However, in up to 40% of cases, patients develop worsening of pain and failed back surgery syndrome (FBSS), which is an important cause of chronic pain with high morbidity and disability. In the last two decades, ozone has been shown to be a new therapeutic option for FBSS due to its analgesic and anti-inflammatory properties...
April 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28605378/functionalization-and-dispersion-of-carbon-nanomaterials-using-an-environmentally-friendly-ultrasonicated-ozonolysis-process
#14
Eudora S Y Yeo, Gary I Mathys, Narelle Brack, Erik T Thostenson, Andrew N Rider
Functionalization of carbon nanomaterials is often a critical step that facilitates their integration into larger material systems and devices. In the as-received form, carbon nanomaterials, such as carbon nanotubes (CNTs) or graphene nanoplatelets (GNPs), may contain large agglomerates. Both agglomerates and impurities will diminish the benefits of the unique electrical and mechanical properties offered when CNTs or GNPs are incorporated into polymers or composite material systems. Whilst a variety of methods exist to functionalize carbon nanomaterials and to create stable dispersions, many the processes use harsh chemicals, organic solvents, or surfactants, which are environmentally unfriendly and may increase the processing burden when isolating the nanomaterials for subsequent use...
May 30, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28584201/ovarian-damages-produced-by-aerosolized-fine-particulate-matter-pm2-5-pollution-in-mice-possible-protective-medications-and-mechanisms
#15
Hui-Fang Gai, Jian-Xiong An, Xiao-Yan Qian, Yong-Jie Wei, John P Williams, Guo-Lan Gao
BACKGROUND: Ambient aerosol fine particulate matter (PM2.5) is associated with male reproductive toxicity in experiments and may have adverse effects in the female. However, studies evaluating the protective effects and precise mechanisms of aspirin, Vitamin C, Vitamin E, or ozone against toxic effects of PM2.5are sparse. This study was conducted to investigate the possible protective effects and mechanisms of aspirin, Vitamin C, Vitamin E, or ozone on fertility in female mice treated with PM2...
June 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28584119/stratospheric-ozone-over-the-united-states-in-summer-linked-to-observations-of-convection-and-temperature-via-chlorine-and-bromine-catalysis
#16
James G Anderson, Debra K Weisenstein, Kenneth P Bowman, Cameron R Homeyer, Jessica B Smith, David M Wilmouth, David S Sayres, J Eric Klobas, Stephen S Leroy, John A Dykema, Steven C Wofsy
We present observations defining (i) the frequency and depth of convective penetration of water into the stratosphere over the United States in summer using the Next-Generation Radar system; (ii) the altitude-dependent distribution of inorganic chlorine established in the same coordinate system as the radar observations; (iii) the high resolution temperature structure in the stratosphere over the United States in summer that resolves spatial and structural variability, including the impact of gravity waves; and (iv) the resulting amplification in the catalytic loss rates of ozone for the dominant halogen, hydrogen, and nitrogen catalytic cycles...
June 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28456921/assessment-of-environmentally-friendly-fuel-emissions-from-in-use-vehicle-exhaust-low-blend-iso-stoichiometric-gem-mixture-as-example
#17
Isaac Schifter, Luis Díaz-Gutiérrez, René Rodríguez-Lara, Carmen González-Macías, Uriel González-Macías
Gasoline-ethanol-methanol fuel blends were formulated with the same stoichiometric air-to-fuel ratio and volumetric energy concentration as any binary ethanol-gasoline blend. When the stoichiometric blends operated in a vehicle, the time period, injector voltage, and pressure for each fuel injection event in the engine corresponded to a given stoichiometric air-to-fuel ratio, and the load was essentially constant. Three low oxygen content iso-stoichiometric ternary gasoline-ethanol-methanol fuel blends were prepared, and the properties were compared with regular-type fuel without added oxygen...
May 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28441489/comparison-of-gasoline-direct-injection-gdi-and-port-fuel-injection-pfi-vehicle-emissions-emission-certification-standards-cold-start-secondary-organic-aerosol-formation-potential-and-potential-climate-impacts
#18
Georges Saliba, Rawad Saleh, Yunliang Zhao, Albert A Presto, Andrew T Lambe, Bruce Frodin, Satya Sardar, Hector Maldonado, Christine Maddox, Andrew A May, Greg T Drozd, Allen H Goldstein, Lynn M Russell, Fabian Hagen, Allen L Robinson
Recent increases in the Corporate Average Fuel Economy standards have led to widespread adoption of vehicles equipped with gasoline direct-injection (GDI) engines. Changes in engine technologies can alter emissions. To quantify these effects, we measured gas- and particle-phase emissions from 82 light-duty gasoline vehicles recruited from the California in-use fleet tested on a chassis dynamometer using the cold-start unified cycle. The fleet included 15 GDI vehicles, including 8 GDIs certified to the most-stringent emissions standard, superultra-low-emission vehicles (SULEV)...
June 6, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28438284/intradiscal-o2o3-rationale-injection-technique-short-and-long-term-outcomes-for-the-treatment-of-low-back-pain-due-to-disc-herniation
#19
REVIEW
Francesco Giurazza, Gianluigi Guarnieri, Kieran J Murphy, Mario Muto
The management of low back pain should always start with a conservative approach; however, when it fails, intervention is required and at that moment the most appropriate choice remains unclear. Before invasive surgery, minimally invasive techniques can be adopted. In European trials and in a trans-Canadian clinical trial 03 ozone has been used successfully. In total over 50,000 patients have been treated safely. Ozone is a gas normally present in the atmosphere with potent oxidizing power; it has been used for percutaneous intradiscal injection combined with oxygen (O2O3) at very low concentrations for 15 years in Europe...
May 2017: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/28376500/suppression-of-retinal-neovascularization-by-anti-ccr3-treatment-in-an-oxygen-induced-retinopathy-model-in-mice
#20
Shuichiro Hirahara, Miho Nozaki, Masaharu Ohbayashi, Norio Hasegawa, Daisuke Ozone, Yuichiro Ogura
PURPOSE: To investigate the association between retinal neovascularization and the CC chemokine receptor-3 (CCR3) in a mouse model of oxygen-induced retinopathy (OIR). METHODS: An OIR model in C57BL/6J mice was used as a retinal neovascularization model. An enzyme-linked immunosorbent assay was performed to evaluate the chronological change in vascular endothelial growth factor A (VEGF-A) and eotaxin expressions. CCR3 and VEGF subtype expression in the retina was examined using real-time RT-PCR, and CCR3, eotaxin, VEGF-A, and CD31 expression was examined immunohistochemically...
2017: Ophthalmic Research
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