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https://www.readbyqxmd.com/read/28705768/the-clinical-and-microbiological-characteristics-of-infections-in-burn-patients-from-the-formosa-fun-coast-dust-explosion
#1
Tzu-Chao Lin, Rui-Xin Wu, Chih-Chien Chiu, Ya-Sung Yang, Yi Lee, Jung-Chung Lin, Feng-Yee Chang
BACKGROUND/PURPOSE: Bloodstream infection is a leading cause of mortality among burn patients. This study aimed to evaluate the risk factors, causative pathogens, and the relationship between bloodstream infections and other infections among burn patients from the Formosa Fun Coast Dust Explosion. METHODS: This retrospective study evaluated the demographic and clinical characteristics, infection types, causative pathogen(s), and isolates' antibiotic susceptibilities from patients who were hospitalized between June 27 and September 31, 2015...
June 22, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28676510/peritoneal-dialysis-in-very-low-birth-weight-neonates
#2
Vesna D Stojanović, Svetlana S Bukarica, Jelena B Antić, Aleksandra D Doronjski
BACKGROUND: The aim of this retrospective study is to evaluate clinical characteristics and outcomes of very low birth weight (VLBW) neonates with acute kidney injury (AKI) treated with peritoneal dialysis (PD). METHODS: This retrospective study included 10 VLBW neonates treated with PD. Intravenous (IV) cannula and umbilical venous catheter were used for the peritoneal access. RESULTS: Mean age at the moment of starting PD was 14.9 ± 9.3 days...
July 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28658091/assessing-estimates-of-patient-safety-derived-from-coded-data
#3
Wazim Narain
The Agency for Healthcare Research and Quality (AHRQ) developed Patient Safety Indicators (PSI) with the goal of detecting and preventing adverse events using administrative data. Use of PSIs to measure safety and quality of care raises questions since they rely heavily on coded data. The goal of this paper is to review literature on AHRQ PSIs, specifically their accuracy in detecting adverse events, and how recent coding changes affect the accuracy of these estimates. The Healthcare Utilization Project (HCUP) National Inpatient Sample (NIS) contains data on more than seven million hospital stays yearly...
July 2017: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://www.readbyqxmd.com/read/28654560/ochrobactrum-anthropi-fulminant-early-onset-neonatal-sepsis-a-case-report-and-review-of-literature
#4
Wasim Khasawneh, Dawood Yusef
Ochrobactrum anthropi is Gram-negative bacteria that cause infection in humans, particularly immunocompromised patients and those with indwelling central venous catheters. O. anthropi is unlikely to cause fulminant sepsis in infected patients. A few cases of late-onset neonatal sepsis have been reported in preterm infants with congenital anomalies. We hereby present the first published case of fulminant early-onset neonatal sepsis in a premature newborn.
June 24, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28587831/clinical-characteristics-and-risk-factors-for-mortality-in-adult-patients-with-persistent-candidemia
#5
Seung Ji Kang, Seong Eun Kim, Uh Jin Kim, Hee-Chang Jang, Kyung-Hwa Park, Jong Hee Shin, Sook In Jung
BACKGROUND: We investigated the clinical characteristics and risk factors for mortality in adults with persistent candidemia. METHODS: All patients ≥18 years old with candidemia in two Korean tertiary hospitals from 2007 to 2014 were investigated. Persistent candidemia was defined as isolation of the same Candida species ≥5 days after initiation of antifungal therapy. Non-persistent candidemia was defined as candidemia persisting for ≤3 days after initiation of antifungal therapy...
June 3, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28549710/complication-rates-observed-in-silicone-and-polyurethane-catheters-of-totally-implanted-central-venous-access-devices-implanted-in-the-upper-arm
#6
Jasmin D Busch, Maren Vens, Catherine Mahler, Jochen Herrmann, Gerhard Adam, Harald Ittrich
PURPOSE: To present frequency and types of complications related to silicone (SI) versus polyurethane (PUR) catheters of totally implanted venous access devices (TIVADs) placed in the upper arm. MATERIAL AND METHODS: A cohort of 2,491 consecutive patients with TIVADs implanted between 2006 and 2015 was retrospectively analyzed. Complications were classified according to SIR guidelines. Pearson χ(2) test was used for categorical variables, and Student t test was used for continuous variables...
May 24, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28518095/use-of-a-central-venous-line-for-fluids-drugs-and-nutrient-administration-in-a-mouse-model-of-critical-illness
#7
Sarah Derde, Steven Thiessen, Chloë Goossens, Thomas Dufour, Greet Van den Berghe, Lies Langouche
This protocol describes a centrally catheterized mouse model of prolonged critical illness. We combine the cecal ligation and puncture method to induce sepsis with the use of a central venous line for fluids, drugs and nutrient administration to mimic the human clinical setting. Critically ill patients require intensive medical support in order to survive. While the majority of patients will recover within a few days, about a quarter of the patients need prolonged intensive care and are at high risk of dying from non-resolving multiple organ failure...
May 2, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28475790/prevalence-of-healthcare-associated-infections-and-antimicrobial-use-among-adult-inpatients-in-singapore-acute-care-hospitals-results-from-the-first-national-point-prevalence-survey
#8
Yiying Cai, Indumathi Venkatachalam, Nancy W Tee, Thean Yen Tan, Asok Kurup, Sin Yew Wong, Chian Yong Low, Yang Wang, Winnie Lee, Yi Xin Liew, Brenda Ang, David C Lye, Angela Chow, Moi Lin Ling, Helen M Oh, Cassandra A Cuvin, Say Tat Ooi, Surinder K Pada, Chong Hee Lim, Jack Wei Chieh Tan, Kean Lee Chew, Van Hai Nguyen, Dale A Fisher, Herman Goossens, Andrea L Kwa, Paul A Tambyah, Li Yang Hsu, Kalisvar Marimuthu
Background: We conducted a national point prevalence survey (PPS) to determine the prevalence of healthcare-associated infections (HAIs) and antimicrobial use (AMU) in Singapore acute-care hospitals. Methods: Trained personnel collected HAI, AMU, and baseline hospital- and patient-level data of adult inpatients from 13 private and public acute-care hospitals between July 2015 and February 2016, using the PPS methodology developed by the European Centre for Disease Prevention and Control...
May 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28475779/comparative-efficacy-of-antimicrobial-central-venous-catheters-in-reducing-catheter-related-bloodstream-infections-in-adults-abridged-cochrane-systematic-review-and-network-meta-analysis
#9
Huey Yi Chong, Nai Ming Lai, Anucha Apisarnthanarak, Nathorn Chaiyakunapruk
Background: The efficacy of antimicrobial central venous catheters (CVCs) remains questionable. In this network meta-analysis, we aimed to assess the comparative efficacy of antimicrobial CVC impregnations in reducing catheter-related infections in adults. Methods: We searched 4 electronic databases (Medline, the Cochrane Central Register of Controlled Trials, Embase, CINAHL) and internet sources for randomized controlled trials, ongoing clinical trials, and unpublished studies up to August 2016...
May 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28464580/-analysis-of-the-spectrum-and-resistance-of-pathogen-causing-sepsis-in-patients-with-severe-acute-pancreatitis
#10
H X Ma, L He, S W Cai, X L Xin, H D Shi, L Zhou, X J Shi
Objective: To investigate the characteristics of spectrum and drug resistance of pathogens causing sepsis in patients with severe acute pancreatitis(SAP). Methods: The clinical data of 63 SAP patients with sepsis admitted in Department of Hepatobiliary, People's Liberation Army General Hospital from January 2014 to December 2015 were retrospectively studied. There were 47 males and 16 females, aged from 22 to 73 years, with an average age of (52±11)years. Samples were collected mainly from: (1)pancreatic and peripancreatic necrosis and abdominal drainage; (2)bile; (3) blood or deep venous catheter; (4) sputum and tracheal catheter and thoracic drainage; (5) urine...
May 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28433610/paraoxonases-and-infectious-diseases
#11
REVIEW
Jordi Camps, Simona Iftimie, Anabel García-Heredia, Antoni Castro, Jorge Joven
The paraoxonases (PON1, PON2 and PON3) are an enzyme family with a high structural homology. All of them have lactonase activity and degrade lipid peroxides in lipoproteins and cells. As such, they play a role in protection against oxidation and inflammation. Infectious diseases are often associated with oxidative stress and an inflammatory response. Infection and inflammation trigger a cascade of reactions in the host, known as the acute-phase response. This response is associated with dramatic changes in serum proteins and lipoproteins, including a decrease in serum PON1 activity...
April 19, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28421643/empiric-antibiotic-regimens-for-neonatal-sepsis-in-australian-and-new-zealand-neonatal-intensive-care-units
#12
Jeremy P Carr, David P Burgner, Rohan S Hardikar, Jim P Buttery
AIM: Neonatal sepsis remains an important cause of morbidity and mortality, and requires prompt empiric treatment. However, only a minority of babies who receive antibiotics for suspected sepsis have an infection. Antimicrobial exposure in infancy has important short- and long-term consequences. There is no consensus regarding empirical antimicrobial regimens. METHODS: The study included a survey of empiric antimicrobial regimens in all tertiary neonatal intensive care units in Australia and New Zealand in 2013-2014...
April 19, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28353459/first-report-of-kocuria-marina-bloodstream-infection-unrelated-to-a-central-venous-catheter-a-mini-review-on-an-emerging-and-under-recognized-opportunistic-pathogen
#13
Giovanna Pulcrano, Michela Balzaretti, Alessia Grosini, Vincenzo Piacentini, Dimitri Poddighe
We report a case of sepsis by Kocuria marina in a 45-year-old woman carrying a midline venous catheter to provide total parenteral nutrition. Despite the finding of K. marina bacteraemia, no bacteria grew from the culture of the catheter tip. As the patient was affected with severe leg ulcers, K. marina bloodstream infection from a skin breakage other than CVC was supposed. K. marina is an emerging opportunistic agent deserving attention and probably under-recognized, as it can be misdiagnosed as Staphylococcus if only conventional microbiological analyses are performed for bacterial identification...
March 1, 2017: Le Infezioni in Medicina
https://www.readbyqxmd.com/read/28260769/morbidity-and-mortality-after-pancreatoduodenectomy-a-five-year-experience-in-bangabandhu-sheikh-mujib-medical-university
#14
B C Das, A S Khan, N E Elahi, M S Uddin, B C Debnath, Z R Khan
Mortality and morbidity was assessed after adoption of a systematic care for patient with pancreatoduodenectomy starting from patient selection and preparation, operative technique, and postoperative care. In this prospective study seventy patients who underwent pancreatoduodenectomy for periampullary carcinoma with curative intent between January 2010 and December 2014 were carefully analyzed prospectively. Patients were selected those who had ampullary carcinoma, lower bile duct carcinoma and small size carcinoma head of pancreas without local invasion and distant metastasis, and the patient who did not have any major disabling comorbid diseases...
January 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28236919/a-randomized-controlled-trial-and-cost-effectiveness-analysis-of-early-cannulation-arteriovenous-grafts-versus-tunneled-central-venous-catheters-in-patients-requiring-urgent-vascular-access-for-hemodialysis
#15
RANDOMIZED CONTROLLED TRIAL
Emma Aitken, Peter Thomson, Leigh Bainbridge, Ram Kasthuri, Belinda Mohr, David Kingsmore
OBJECTIVE: Early cannulation arteriovenous grafts (ecAVGs) are proposed as an alternative to tunneled central venous catheters (TCVCs) in patients requiring immediate vascular access for hemodialysis (HD). We compared bacteremia rates in patients treated with ecAVG and TCVC. METHODS: The study randomized 121 adult patients requiring urgent vascular access for HD in a 1:1 fashion to receive an ecAVG with or without (+/-) an arteriovenous fistula (AVF; n = 60) or TCVC+/-AVF (n = 61)...
March 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28205241/septic-transfusion-case-caused-by-a-platelet-pool-with-visible-clotting-due-to-contamination-with-staphylococcus-aureus
#16
Maria Loza-Correa, Yuntong Kou, Mariam Taha, Miloslav Kalab, Jennifer Ronholm, Patrick M Schlievert, Michael P Cahill, Robert Skeate, Christine Cserti-Gazdewich, Sandra Ramirez-Arcos
BACKGROUND: Contamination of platelet concentrates (PCs) with Staphylococcus aureus is one of the most significant ongoing transfusion safety risks in developed countries. CASE REPORT: This report describes a transfusion reaction in an elderly patient diagnosed with acute myeloid leukemia, transfused with a 4-day-old buffy coat PC through a central venous catheter. The transfusion was interrupted when a large fibrous clot in the PC obstructed infusion pump flow...
May 2017: Transfusion
https://www.readbyqxmd.com/read/28124965/-bacteremia-caused-by-ciprofloxacin-resistant-salmonella-serotype-kentucky-a-case-report-and-the-review-of-literature
#17
Tuba Müderris, Fatma Yekta Ürkmez, Şeref Alp Küçüker, Muhammet Fethi Sağlam, Gül Ruhsar Yılmaz, Rahmet Güner, Revasiye Güleşen, Ziya Cibali Açıkgöz
Salmonella infections can be seen in four clinical types, namely gastroenteritis, bacteremia/sepsis, enteric fever and carriage. These infections can result in uncomplicated diarrhea in most cases, but can lead to invasive disease requiring antimicrobial therapy and can be life-threatening in elderly or immunocomprimised patients. Broad-spectrum cephalosporins and fluoroquinolones are crucial options in the treatment of the invasive infections. Ciprofloxacin resistance is rarely seen in non-typhoid Salmonella enterica isolates, and only in S...
October 2016: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/27978519/the-use-of-peripherally-inserted-central-catheter-in-amyotrophic-lateral-sclerosis-patients-at-a-later-stage
#18
Raul Juntas-Morales, Nicolas Pageot, Sébastien Alphandéry, William Camu
BACKGROUND/AIMS: To describe the use of peripherally inserted central catheter (PICC), in amyotrophic lateral sclerosis (ALS) at a later stage. METHODS: Twenty-five ALS patients in the later stages of the disease underwent PICC insertion followed by parenteral nutrition (PN). For all of them, gastrostomy was non-feasible. Patients were followed until death and monitored for complications. RESULTS: PICC insertion was successful in all patients...
2017: European Neurology
https://www.readbyqxmd.com/read/27942705/association-of-a-clinical-practice-guideline-with-blood-culture-use-in-critically-ill-children
#19
Charlotte Z Woods-Hill, James Fackler, Kristen Nelson McMillan, Judith Ascenzi, Diego A Martinez, Matthew F Toerper, Annie Voskertchian, Elizabeth Colantuoni, Sybil Ann Klaus, Scott Levin, Aaron M Milstone
Importance: Sepsis and septic shock are common and, at times, fatal in pediatrics. Blood cultures are often obtained when clinicians suspect sepsis, yet are low-yield with a false-positive rate up to 50%. Objectives: To determine whether a novel, 2-part, clinical practice guideline could decrease the rates of total blood cultures and cultures collected from central venous catheters in critically ill children and to examine the effect of the guideline on patient outcomes...
February 1, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/27891260/intravenous-vitamin-c-administered-as-adjunctive-therapy-for-recurrent-acute-respiratory-distress-syndrome
#20
Amit Bharara, Catherine Grossman, Daniel Grinnan, Aamer Syed, Bernard Fisher, Christine DeWilde, Ramesh Natarajan, Alpha A Berry Fowler
This case report summarizes the first use of intravenous vitamin C employed as an adjunctive interventional agent in the therapy of recurrent acute respiratory distress syndrome (ARDS). The two episodes of ARDS occurred in a young female patient with Cronkhite-Canada syndrome, a rare, sporadically occurring, noninherited disorder that is characterized by extensive gastrointestinal polyposis and malabsorption. Prior to the episodes of sepsis, the patient was receiving nutrition via chronic hyperalimentation administered through a long-standing central venous catheter...
2016: Case Reports in Critical Care
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