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systematic inflammation

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https://www.readbyqxmd.com/read/28443243/association-between-hashimoto-s-thyroiditis-and-thyroid-cancer-in-64-628-patients
#1
Christina Resende de Paiva, Christian Grønhøj, Ulla Feldt-Rasmussen, Christian von Buchwald
BACKGROUND: The incidence of thyroid cancer (TC) is increasing although explanatory causes are lacking. A link between cancer and inflammation is well documented but unclear for autoimmune thyroid diseases and TC. We aimed to systematically review the association between Hashimoto's thyroiditis (HT) and papillary, follicular, medullary, anaplastic thyroid carcinoma, and thyroid lymphoma (TL). METHODS: PubMed, OVID Medline, Google Scholar, and the Cochrane Library were searched from 1955 to 2016...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28442577/association-between-exposure-in-the-cement-production-industry-and-non-malignant-respiratory-effects-a-systematic-review
#2
Anne Kristin Møller Fell, Karl Christian Nordby
OBJECTIVES: Based on findings from a systematic literature search, we present and discuss the evidence for an association between exposure to cement dust and non-malignant respiratory effects in cement production workers. DESIGN AND SETTING: Systematic literature searches (MEDLINE and Embase) were performed. Outcomes were restricted to respiratory symptoms, lung function indices, asthma, chronic bronchitis, chronic obstructive pulmonary disease, pneumoconiosis, induced sputum or fraction of exhaled nitric oxide (FeNO) measurements...
April 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28442299/the-anti-inflammatory-function-of-high-density-lipoprotein-in-type-ii-diabetes-a-systematic-review
#3
Roosmarijn F H Lemmers, Mandy van Hoek, Aloysius G Lieverse, Adrie J M Verhoeven, Eric J G Sijbrands, Monique T Mulder
BACKGROUND: Inflammation is a pathophysiological factor in diabetes and its cardiovascular complications. High-density lipoprotein (HDL) suppresses inflammation in healthy individuals. The relationship of HDL with diabetes and cardiovascular disease may be explained by HDL function rather than by HDL cholesterol level. In diabetes, HDL seems to become dysfunctional. OBJECTIVE: We performed a systematic review to answer the following research questions: Is the anti-inflammatory function of HDL diminished in individuals with diabetes and if so, what causes this? METHODS: We systematically searched Medline and Embase and included original research articles on the anti-inflammatory effects of HDL or HDL-based interventions in diabetes or diabetes models...
March 31, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28441120/prevalence-of-trachoma-in-northern-benin-results-from-11-population-based-prevalence-surveys-covering-26-districts
#4
Amadou Alfa Bio, Pelagie M Boko, Yannelle A Dossou, Jean-Jacques Tougoue, Achille Kabore, Ignace Sounouvou, Jean-Eudes Biaou, Lionel Nizigama, Paul Courtright, Anthony W Solomon, Lisa Rotondo, Wilfrid Batcho, Dorothée Kinde-Gazard
AIMS: We sought to evaluate trachoma prevalence in all suspected-endemic areas of Benin. METHODS: We conducted population-based surveys covering 26 districts grouped into 11 evaluation units (EUs), using a two-stage, systematic and random, cluster sampling design powered at EU level. In each EU, 23 villages were systematically selected with population proportional to size; 30 households were selected from each village using compact segment sampling. In selected households, we examined all consenting residents aged one year or above for trichiasis, trachomatous inflammation - follicular (TF), and trachomatous inflammation - intense...
April 25, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28439503/circulating-cell-free-nucleic-acids-as-potential-biomarkers-for-sarcopenia-a-step-toward-personalized-medicine
#5
EDITORIAL
Gita Shafiee, Ramin Heshmat, Bagher Larijani
Sarcopenia is an age-related loss of muscle mass and function, leading to disability, morbidity and increased mortality in older people. Given the relatively high prevalence and related- outcome of the disease, correct diagnosis, screening, monitoring and treatment of sarcopenia are needed in clinical practice. Recent researches have focused on cell-free nucleic acids, which are released into the circulation following cell death, as a potential biomarker of aging and systematic inflammation. It seems that the diagnosis and treatment of sarcopenia can be possible by the help of the analysis of cell-free nucleic acids as noninvasive method...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/28438133/evaluation-of-the-enhanced-meningitis-surveillance-system-yendi-municipality-northern-ghana-2010-2015
#6
Basil Benduri Kaburi, Chrysantus Kubio, Ernest Kenu, Kofi Mensah Nyarko, Jacob Yakubu Mahama, Samuel Oko Sackey, Edwin Andrew Afari
BACKGROUND: Meningitis is the inflammation of the meninges of the brain and or spinal cord. Global mortality rates vary from 2% to 30%. Epidemic meningitis remains a public health concern along the meningitis belt of Africa. Despite the operation of an enhanced meningitis surveillance system in Ghana, institutional mortality rates are estimated to range from 36% to 50%. In 2014, Yendi recorded 83 confirmed cases; with focal epidemics in some sub-municipals. We evaluated the system over a five-year period to find out whether it was achieving its objectives of systematic collection and analyses of data for the prevention or early detection of meningitis epidemics...
April 24, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28437366/the-impact-of-residual-subgingival-cement-on-biological-complications-around-dental-implants-a-systematic-review
#7
Alessandro Quaranta, Zhuo Wei Lim, Joyce Tang, Vittoria Perrotti, Jonathan Leichter
OBJECTIVES: To perform a systematic review on the impact of residual subgingival cement on peri-implant diseases and crestal bone loss. MATERIAL AND METHODS: MEDLINE, SCOPUS, ISI Web of Knowledge and Cochrane Central Register of Controlled Trials (CENTRAL) databases were used to identify articles published without time limits. RESULTS: A total of 6 articles were selected for a total of 389 patients (687 implants). The studies were heterogeneous and had a moderate-to-high risk of bias, but met the inclusion criteria...
April 21, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28436759/the-roles-of-micrornas-in-spinal-cord-injury
#8
Zhongju Shi, Hengxing Zhou, Lu Lu, Xueying Li, Zheng Fu, Jun Liu, Yi Kang, Zhijian Wei, Bin Pan, Lu Liu, Xiaohong Kong, Shiqing Feng
BACKGROUND AND PURPOSE: Spinal cord injury (SCI) involves serious damage that can result in abnormal or absent motor and sensory functions and a disruption of autonomic function, and a series of pathological reactions occur after the injury. As a type of small non-coding RNA, microRNAs (miRNAs) have been verified to inhibit gene expression via posttranscriptional regulation. This review mainly focuses on recent advances regarding the roles of miRNAs following SCI. METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were adopted...
April 24, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28436720/efficacy-and-safety-of-statins-and-exercise-combination-therapy-compared-to-statin-monotherapy-in-patients-with-dyslipidaemia-a-systematic-review-and-meta-analysis
#9
Ya-Jun Gui, Cai-Xiu Liao, Qiong Liu, Yuan Guo, Tao Yang, Jing-Yuan Chen, Ya-Ting Wang, Jia-Hui Hu, Dan-Yan Xu
Background Statin treatment in association with physical exercise can substantially reduce mortality in dyslipidaemic individuals. However, the available data to compare the efficacy and safety of statins and exercise combination therapy with statin monotherapy are limited. Design Systematic review and meta-analysis. Methods We systematically searched PubMed, Embase and the Cochrane Library from database inception until December 2016. We included randomised and non-randomised studies that compared the efficacy and safety of statins and exercise combination therapy with statin monotherapy in patients with dyslipidaemia...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28430540/demystifying-orbital-emergencies-a-pictorial-review
#10
Viet D Nguyen, Achint K Singh, Wilson B Altmeyer, Bundhit Tantiwongkosi
Imaging of the orbit plays an important role in the workup of orbital emergencies. Orbital imaging is particularly useful in the emergency department, where clinical history and physical examination may be limited or delayed until the exclusion or treatment of more life-threatening conditions. Cross-sectional orbital imaging with multidetector computed tomography (CT) and magnetic resonance (MR) imaging is commonly performed in addition to ultrasonography. In an emergent setting, CT is the preferred modality when evaluating for intraorbital foreign bodies, fractures, or calcifications within a mass lesion...
April 21, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28428284/acute-presentation-of-autoimmune-hepatitis-a-multicentre-study-with-detailed-histological-evaluation-in-a-large-cohort-of-patients
#11
Hiep Nguyen Canh, Kenichi Harada, Hirofumi Ouchi, Yasunori Sato, Koichi Tsuneyama, Masayoshi Kage, Masayuki Nakano, Kaname Yoshizawa, Atsushi Takahashi, Masanori Abe, Jong-Hon Kang, Kazuhiko Koike, Ayano Inui, Tomoo Fujisawa, Akinobu Takaki, Teruko Arinaga-Hino, Takuji Torimura, Yoshiyuki Suzuki, Keiichi Fujiwara, Mikio Zeniya, Hiromasa Ohira, Atsushi Tanaka, Hajime Takikawa
AIMS: Although liver biopsy is crucial to diagnose and guide treatment decisions, a detailed histological analysis of autoimmune hepatitis (AIH) with clinically acute presentations has not yet been performed. This study aimed to characterise the histological features and explore potential histological hallmarks to diagnose the acute presentation of AIH. METHODS: We systematically evaluated liver specimens of 87 adult patients with acute presentation of AIH retrospectively enrolled from Japanese multicentre facilities...
April 20, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28428221/circulating-levels-of-interleukin-1-receptor-antagonist-and-risk-of-cardiovascular-disease-meta-analysis-of-six-population-based-cohorts
#12
Christian Herder, Tonia de Las Heras Gala, Maren Carstensen-Kirberg, Cornelia Huth, Astrid Zierer, Simone Wahl, Julie Sudduth-Klinger, Kari Kuulasmaa, David Peretz, Symen Ligthart, Brenda W C Bongaerts, Abbas Dehghan, M Arfan Ikram, Antti Jula, Frank Kee, Arto Pietilä, Olli Saarela, Tanja Zeller, Stefan Blankenberg, Christa Meisinger, Annette Peters, Michael Roden, Veikko Salomaa, Wolfgang Koenig, Barbara Thorand
OBJECTIVE: Interleukin (IL)-1β represents a key cytokine in the development of cardiovascular disease (CVD). IL-1β is counter-regulated by IL-1 receptor antagonist (IL-1RA), an endogenous inhibitor. This study aimed to identify population-based studies on circulating IL-1RA and incident CVD in a systematic review, estimate the association between IL-1RA and incident CVD in a meta-analysis, and to test whether the association between IL-1RA and incident CVD is explained by other inflammation-related biomarkers in the MONICA/KORA Augsburg case-cohort study (Multinational Monitoring of Trends and Determinants in Cardiovascular Disease/Cooperative Health Research in the Region of Augsburg)...
April 20, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28423365/preoperative-neutrophil-to-lymphocyte-ratio-is-a-predictor-of-survival-of-epithelial-ovarian-cancer-a-systematic-review-and-meta-analysis-of-observational-studies
#13
Zhuo Yang, Jia-Hui Gu, Cui-Shan Guo, Xin-Hui Li, Wen-Chao Yang
Inflammation plays an important role in the development and progression of epithelial ovarian cancer (EOC). However, no meta-analysis has comprehensively and quantitatively investigated the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) in EOC patients. Therefore, we performed a meta-analysis to quantify the prognostic impact of this biomarker. We searched the PubMed and Web of Science databases from their inception through December 31, 2016, and examined observational studies evaluating the association of preoperative NLR with progression-free survival (PFS) and overall survival (OS) of EOC patients...
April 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/28422706/adult-hippocampal-neurogenesis-an-important-target-associated-with-antidepressant-effects-of-exercise
#14
Lina Sun, Qingshan Sun, Jinshun Qi
Depression is a prevalent devastating mental disorder that affects the normal life of patients and brings a heavy burden to whole society. Although many efforts have been made to attenuate depressive/anxiety symptoms, the current clinic antidepressants have limited effects. Scientists have long been making attempts to find some new strategies that can be applied as the alternative antidepressant therapy. Exercise, a widely recognized healthy lifestyle, has been suggested as a therapy that can relieve psychiatric stress...
April 19, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/28420441/autologous-bone-marrow-derived-cell-transplantation-in-decompensated-alcoholic-liver-disease-what-is-the-impact-on-liver-histology-and-gene-expression-patterns
#15
Nicolas Lanthier, Nathalie Lin-Marq, Laura Rubbia-Brandt, Sophie Clément, Nicolas Goossens, Laurent Spahr
BACKGROUND: Liver stem cell therapy (SCT) has been suggested as a promising means to improve liver regeneration in advanced liver disease. However, data from trials are heterogeneous, with no systematic histological evaluation. The aim of this study is to specifically analyze the effect of autologous SCT on liver regeneration and on gene expression changes. METHODS: Individuals in the randomized controlled trial of SCT in alcoholic hepatitis with paired liver biopsies were included (n = 58)...
April 18, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28416092/cytokines-and-c-reactive-protein-alterations-with-respect-to-cognitive-impairment-in-schizophrenia-and-bipolar-disorder-a-systematic-review
#16
REVIEW
Błażej Misiak, Bartłomiej Stańczykiewicz, Kamila Kotowicz, Janusz K Rybakowski, Jerzy Samochowiec, Dorota Frydecka
BACKGROUND: The aim of this article was to perform a systematic review of studies investigating the association between peripheral levels of cytokines and C-reactive protein (CRP), cytokine gene polymorphisms and cognition in patients with schizophrenia and bipolar disorder (BD). METHODS: The following databases: PubMed, CINAHL Complete, Academic Search Complete, ERIC and Health Source: Nursing/Academic Edition databases were searched according to the PRISMA guidelines...
April 13, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28415734/prognostic-significance-of-neutrophil-to-lymphocyte-ratio-in-biliary-tract-cancers-a-systematic-review-and-meta-analysis
#17
REVIEW
Haowen Tang, Wenping Lu, Bingmin Li, Chonghui Li, Yinzhe Xu, Jiahong Dong
BACKGROUND: Inflammation was considered to perform crucial roles in the development and metastasis of malignancies. A heightened neutrophil-lymphocyte ratio has been described to be associated with detrimental survivals in different malignancies. Debate remains over the impact of heightened neutrophil-lymphocyte ratio on survivals in biliary tract cancer. The review evaluated the prognostic value of neutrophil-lymphocyte ratio in biliary tract cancer. METHODS: MEDLINE, the Cochrane Library, EMBASE, and the Chinese SinoMed were systematically searched for relevant articles...
March 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/28414969/cytokines-in-the-management-of-rotavirus-infection-a-systematic-review-of-in-vivo-studies
#18
REVIEW
Gopalsamy Rajiv Gandhi, Victor Santana Santos, Marina Denadai, Valdete Kaliane da Silva Calisto, Jullyana de Souza Siqueira Quintans, Ana Mara de Oliveira E Silva, Adriano Antunes de Souza Araújo, Narendra Narain, Luis Eduardo Cuevas, Lucindo José Quintans Júnior, Ricardo Queiroz Gurgel
OBJECTIVE: Rotavirus is a leading cause of childhood diarrhoea. Rotavirus vaccines are effective against severe rotavirus gastroenteritis, but have lower efficacy in low income countries in Africa. Anti-rotavirus treatment is not available. This study reviews the literature of animal studies evaluating whether cytokine mediated pathways of immune activation could improve rotavirus therapy. METHODS: We performed a systematic review of articles in English published from 2010 to 2016 reporting agents with in vivo antirotavirus activity for the management of rotavirus infection...
April 14, 2017: Cytokine
https://www.readbyqxmd.com/read/28413186/the-characterization-of-a-full-thickness-excision-open-foot-wound-model-in-n5-streptozotocin-stz-induced-type-2-diabetic-rats-that-mimics-diabetic-foot-ulcer-in-terms-of-reduced-blood-circulation-higher-c-reactive-protein-elevated-inflammation-and-reduced-cell
#19
Caroline Oi-Ling Yu, Kwok-Sui Leung, Kwok-Pui Fung, Francis Fu-Yuen Lam, Ethel Sau-Kuen Ng, Kit-Man Lau, Simon Kwoon-Ho Chow, Wing-Hoi Cheung
Delayed foot wound healing is a major complication attributed to hyperglycemia in type 2 diabetes mellitus (DM) patients, and these wounds may develop into foot ulcers. There are at least two types of DM wound models used in rodents to study delayed wound healing. However, clinically relevant animal models are not common. Most models use type 1 DM rodents or wounds created on the back rather than on the foot. An open full-thickness excision wound on the footpad of type 2 DM rats is more clinically relevant, but such a model has not yet been characterized systematically...
April 11, 2017: Experimental Animals
https://www.readbyqxmd.com/read/28412700/takayasu-arteritis-and-spondyloarthritis-coincidence-or-association-a-study-of-14-cases
#20
Elodie Rivière, Laurent Arnaud, Mikael Ebbo, Yannick Allanore, Pascal Claudepierre, Emmanuelle Dernis, Jean-Marc Ziza, Corinne Miceli-Richard, Peggy Philippe, Christophe Richez, Martin Soubrier, Rakiba Belkhir, Raphaèle Seror, Xavier Mariette, Stephan Pavy
OBJECTIVE: Spondyloarthritis (SpA) and Takayasu arteritis (TA) are 2 chronic inflammatory diseases; their coexistence in a single patient is uncommon. The aims of our study were to describe clinical features of patients having SpA associated with TA and to identify some characteristics of the types of patients with SpA associated with TA. We also analyzed treatments used in this context. METHODS: This French multicenter retrospective survey called for observations on behalf of the Club Rhumatismes et Inflammations, with a standardized questionnaire established by the investigators...
April 15, 2017: Journal of Rheumatology
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