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https://www.readbyqxmd.com/read/28545198/assessing-breast-cancer-awareness-in-thai-women-validation-of-the-breast-cancer-awareness-scale-b-cas
#1
Nitchamon Rakkapao, Supannee Promthet, Malcolm Anthony Moore, Solikhah Solikhah, Cameron Hurst
Background: Raising breast cancer awareness is a well-established first line strategy to reduce breast cancer mortality. A properly validated instrument is needed to gain a better understanding of breast cancer awareness. Objective: The objective of this study was to develop and validate an instrument to assess breast cancer awareness in Thai women. Methods: In this study, we develop and evaluate the validity of the Breast Cancer Awareness Scale (B-CAS). Construct validity was evaluated by using exploratory factor analysis and confirmatory factor analysis, and criterion validity was investigated using ROC curves to examine the associations between B-CAS subscales and breast self-examination...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28545195/perceived-risk-of-cervical-cancer-and-barriers-to-screening-among-secondary-school-female-teachers-in-al-hassa-saudi-arabia
#2
Marwa Rashad Salem, Tarek Tawfik Amin, Abdulhamid Abdulrahman Alhulaybi, Abdulaziz Sami Althafar, Rehab Ahmed Abdelhai
Background: No previous studies had addressed the perceived risk of cervical cancer (CC) and its influence on screening practices and perceived barriers in Saudi Arabia. Methods: This cross-sectional study was conducted on 506 randomly selected Saudi female secondary school teachers in Al Hassa, Saudi Arabia to assess their level of knowledge about risk factors and signs of CC in relation to perceived risk and to characterize CC screening compliance using a self-administered questionnaire. Results: Of the included female Saudi teachers, 65...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28545063/financial-distress-in-patients-with-advanced-cancer
#3
Cécile Barbaret, Christelle Brosse, Wadih Rhondali, Murielle Ruer, Léa Monsarrat, Patrick Michaud, Anne Marie Schott, Marvin Delgado-Guay, Eduardo Bruera, Stéphane Sanchez, Marilène Filbet
PURPOSE: We examined the frequency and severity of financial distress (FD) and its association with quality of life (QOL) and symptoms among patients with advanced cancer in France. DESIGN: In this cross-sectional study, 143 patients with advanced cancer were enrolled. QOL was assessed using the Functional Assessment of Cancer General (FACT-G) and symptoms assessed using Edmonton Assessment System (ESAS) and Hospital Anxiety and Depression Scale (HADS). FD was assessed using a self-rated numeric scale from 0 to 10...
2017: PloS One
https://www.readbyqxmd.com/read/28544780/spinal-metastatic-disease-a-review-of-the-role-of-the-multidisciplinary-team
#4
REVIEW
Mark Curtin, Robert P Piggott, Evelyn P Murphy, Sudarshan Munigangaiah, Joseph F Baker, John P McCabe, Aiden Devitt
Historically, a simple approach centered on palliation was applicable to the majority of patients with metastatic spinal disease. With advances in diagnosis and treatment, a more complicated algorithm has devolved requiring a multidisciplinary approach with institutional commitment and support. We performed a database review including pertinent articles exploring the multidisciplinary management of spinal metastatic disease. The wide variation in clinical presentation and tumor response to treatment necessitates a multidisciplinary approach that integrates the diagnosis and treatment of the cancer, symptom management, and rehabilitation for optimal care of patients with spinal metastases...
May 24, 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28544470/patients-help-seeking-experiences-and-delaying-in-breast-cancer-diagnosis-a-qualitative-study
#5
Mariko Oshiro, Midori Kamizato
AIM: To identify the influencing factors in help-seeking behavior by comparing delayers with non-delayers in Japanese female patients with breast cancer. METHODS: This is a descriptive qualitative study. A total of 21 female patients with breast cancer (nine delayers and 12 non-delayers) who were at least 3 months to 5 years postdiagnosis were recruited from two hospitals in Okinawa, Japan. Semistructured interviews were carried out and the results were analyzed by using a qualitative inductive approach...
May 23, 2017: Japan Journal of Nursing Science: JJNS
https://www.readbyqxmd.com/read/28543939/symptom-appraisal-help-seeking-and-lay-consultancy-for-symptoms-of-head-and-neck-cancer
#6
J A Queenan, Benjamin Gottlieb, Deb Feldman-Stewart, Stephen Hall, Jonathan Irish, Patti Groome
BACKGROUND: Early diagnosis is important in head and neck cancer (HNC) patients in order to maximize the effectiveness of the treatments and minimize the debilitation associated with both the cancer and the invasive treatments of advanced disease. Many patients present with advanced disease, and there is little understanding as to why. This study investigated patients' symptom appraisal, help-seeking and lay-consultancy up to the time they first went to see a health care professional (HCP)...
May 23, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28543072/obstructive-sleep-apnea-in-the-irradiated-head-and-neck-cancer-patient
#7
Phillip Huyett, Seungwon Kim, Jonas T Johnson, Ryan J Soose
OBJECTIVES/HYPOTHESIS: To assess the prevalence of obstructive sleep apnea (OSA) in head and neck cancer (HNSCC) patients treated with radiation therapy. STUDY DESIGN: Prospective case series without comparison group. METHODS: Patients who underwent radiation therapy for oropharyngeal or laryngeal squamous cell carcinoma completed a 3-night home sleep test (HST), Epworth Sleepiness Scale, Functional Outcomes of Sleep Questionnaire, and University of Washington Quality of Life questionnaire...
May 23, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28542894/risk-factors-of-falls-among-inpatients-with-cancer
#8
M D Jun, K M Lee, S A Park
AIM: To investigate the risk factors and predictors of falls according to the general characteristics, conscious state, physical condition and treatment of hospitalized patients with cancer. BACKGROUND: Inpatients with cancer experience falls more frequently than those without cancer, and the degree of injuries is more severe among inpatients with cancer. A specific fall prevention strategy is needed for each patient. Prevention of falls in patients with cancer is very important for improving the quality of nursing care...
May 25, 2017: International Nursing Review
https://www.readbyqxmd.com/read/28542677/association-of-previous-clinical-breast-examination-with-reduced-delays-and-earlier-stage-breast-cancer-diagnosis-among-women-in-peru
#9
Anya Romanoff, Tara Hayes Constant, Kay M Johnson, Manuel Cedano Guadiamos, Ana María Burga Vega, Joseph Zunt, Benjamin O Anderson
Importance: Mammographic screening is impractical in most of the world where breast cancers are first identified based on clinical signs and symptoms. Clinical breast examination may improve early diagnosis directly by finding breast cancers at earlier stages or indirectly by heightening women's awareness of breast health concerns. Objective: To investigate factors that influence time to presentation and stage at diagnosis among patients with breast cancer to determine whether history of previous clinical breast examination is associated with earlier presentation and/or earlier cancer stage at diagnosis...
May 25, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28542626/the-relationship-between-pro-inflammatory-cytokines-and-pain-appetite-and-fatigue-in-patients-with-advanced-cancer
#10
Ørnulf Paulsen, Barry Laird, Nina Aass, Tor Lea, Peter Fayers, Stein Kaasa, Pål Klepstad
BACKGROUND: Systemic inflammation is associated with reduced quality of life and increased symptoms in patients with advanced cancer. The aims of this study were to examine the relationships between inflammatory biomarkers and the Patient Reported Outcome Measures (PROMs) of pain, appetite and fatigue; and to explore whether levels of baseline biomarkers were associated with changes in these PROMs following treatment with corticosteroids. MATERIAL AND METHODS: An exploratory analysis was done on a trial examining the analgesic properties of corticosteroids in patients with advanced cancer...
2017: PloS One
https://www.readbyqxmd.com/read/28541759/the-psychometric-properties-of-an-arabic-version-of-the-pedsql-multidimensional-fatigue-scale-tested-for-children-with-cancer
#11
Ekhlas Al-Gamal, Tony Long
Fatigue is considered to be one of the most reported symptoms experienced by children with cancer. A major aim of this study was to develop an Arabic version of the Pediatric Quality of Life (PedsQL) Multidimensional Fatigue Scale (child report) and to test its psychometric proprieties for the assessment of fatigue in Arabic children with cancer. The PedsQL Multidimensional Fatigue Scale (Arabic version) and the PedsQL TM 4.0 Generic Core scale (existing Arabic version) were completed by 70 Jordanian children with cancer...
May 25, 2017: Compr Child Adolesc Nurs
https://www.readbyqxmd.com/read/28541629/adult-granulosa-cell-tumors-of-the-ovary-a-retrospective-study-of-30-cases-with-respect-to-the-expression-of-steroid-synthesis-enzymes
#12
Sachiko Kitamura, Kaoru Abiko, Noriomi Matsumura, Hidekatsu Nakai, Yumiko Akimoto, Hirotoshi Tanimoto, Ikuo Konishi
OBJECTIVE: Some, but not all, granulosa cell tumors are characterized by estrogen production. This study was designed to determine whether there are clinical or pathological variations in granulosa cell tumors in relation to the expression of sex steroid synthesis enzymes. METHODS: Clinical symptoms, serum hormonal values, and histology of 30 granulosa cell tumor patients who underwent surgery between 2002 and 2014 were retrospectively reviewed. RESULTS: Most patients presented with abnormal genital bleeding including abnormal menstrual cycles...
July 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28541420/surgical-decompression-of-high-grade-spinal-cord-compression-from-hormone-refractory-metastatic-prostate-cancer
#13
Muhammad Omar Chohan, Sweena Kahn, Gustav Cederquist, Anne S Reiner, Joseph Schwab, Ilya Laufer, Mark Bilsky
BACKGROUND: Spine and nonspine skeletal metastases occur in more than 80% of patients with prostate cancer. OBJECTIVE: To examine the characteristics of the patient population undergoing surgery for the treatment of prostate cancer metastatic to the spine. METHODS: A retrospective chart review was performed on all patients treated at our institution from June 1993 to August 2014 for surgical management of metastatic spine disease from prostate cancer...
May 24, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28541100/patient-education-and-mind-diversion-in-supportive-care
#14
Salima Sadruddin, Rafat Jan, Adnan A Jabbar, Kashmira Nanji, Ambreen Tharani Name
Cancer is a growing health problem worldwide. Common treatments include surgery, chemotherapy and radiation therapy. Systemic anti-cancer medications often result in an array of physical and psychological side effects. Supportive care assists patients with cancer in managing multidimensional symptoms that result from treatment or the illness itself. This review discusses supportive care and examines patient counselling and mind-diversion activities, which are safe and cost-effective strategies. Improving cancer patients' health and wellbeing should be encouraged in oncology nursing practice and by teaching students the knowledge and skills needed to provide supportive care...
May 25, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28540668/fatigue-in-patients-with-low-grade-glioma-systematic-evaluation-of-assessment-and-prevalence
#15
REVIEW
Ellen M P van Coevorden-van Loon, Marijke B Coomans, Majanka H Heijenbrok-Kal, Gerard M Ribbers, Martin J van den Bent
Fatigue is the most prevalent and disabling symptom in cancer patients. Yet, scientific literature on this topic is scarce and reports disparate results. This study systematically reviews how fatigue is assessed in patients with low-grade glioma and evaluates its prevalence in LGG patients. A systematic literature search was performed in PubMed, Embase and PsychINFO for articles reporting on fatigue in patients with LGG. Two reviewers independently extracted data from selected articles. Inclusion criteria were: (1) patients with suspected or confirmed LGG; (2) fatigue was assessed as primary or secondary outcome measure; (3) age≥ 18 years; (4) full-length article written in English or Dutch...
May 24, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28540637/importance-of-human-peritoneal-mesothelial-cells-in-the-progression-fibrosis-and-control-of-gastric-cancer-inhibition-of-growth-and-fibrosis-by-tranilast
#16
Hiroto Saito, Sachio Fushida, Shinichi Harada, Tomoharu Miyashita, Katsunobu Oyama, Takahisa Yamaguchi, Tomoya Tsukada, Jun Kinoshita, Hidehiro Tajima, Itasu Ninomiya, Tetsuo Ohta
BACKGROUND: Scirrhous gastric cancer is an intractable disease with a high incidence of peritoneal dissemination and obstructive symptoms (e.g., ileus, jaundice, and hydronephrosis) arising from accompanying marked fibrosis. Microenvironmental interactions between cancer cells and cancer-associated fibroblasts are the suggested cause of the disease. We elucidated the mechanisms of tumor growth and fibrosis using human peritoneal mesothelial cells (HPMCs) and investigated the effects of tranilast treatment on cells and a xenograft mouse model of fibrosis...
May 24, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28540564/digital-breast-tomosynthesis-dbt-recommendations-from-the-italian-college-of-breast-radiologists-icbr-by-the-italian-society-of-medical-radiology-sirm-and-the-italian-group-for-mammography-screening-gisma
#17
Daniela Bernardi, Paolo Belli, Eva Benelli, Beniamino Brancato, Lauro Bucchi, Massimo Calabrese, Luca A Carbonaro, Francesca Caumo, Beatrice Cavallo-Marincola, Paola Clauser, Chiara Fedato, Alfonso Frigerio, Vania Galli, Livia Giordano, Paolo Giorgi Rossi, Paola Golinelli, Doralba Morrone, Giovanna Mariscotti, Laura Martincich, Stefania Montemezzi, Carlo Naldoni, Adriana Paduos, Pietro Panizza, Federica Pediconi, Fiammetta Querci, Antonio Rizzo, Gianni Saguatti, Alberto Tagliafico, Rubina M Trimboli, Marco Zappa, Chiara Zuiani, Francesco Sardanelli
This position paper, issued by ICBR/SIRM and GISMa, summarizes the evidence on DBT and provides recommendations for its use. In the screening setting, DBT in adjunct to digital mammography (DM) increased detection rate by 0.5-2.7‰ and decreased false positives by 0.8-3.6% compared to DM alone in observational and double-testing experimental studies. The reduction in recall rate could be less prominent in those screening programs which already have low recall rates with DM. The increase in radiation exposure associated with DM/DBT protocols has been solved by the introduction of synthetic mammograms (sDM) reconstructed from DBT datasets...
May 25, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28540256/concurrent-afatinib-and-whole-brain-radiotherapy-in-exon-19-del-egfr-mutant-lung-adenocarcinoma-a-case-report-and-mini-review-of-the-literature
#18
Chukwuka Eze, Nina-Sophie Hegemann, Olarn Roengvoraphoj, Maurice Dantes, Farkhad Manapov
Leptomeningeal metastases (LM) are found in approximately 3.8% of non-small cell lung cancer cases with an increased incidence in adenocarcinoma, and approximately one-third of patients will present with concomitant brain metastases. We report the case of a 50-year-old male patient with stage IV exon 19-del-EGFR mutant lung adenocarcinoma who progressed on second-generation TKI therapy with manifestation of symptomatic simultaneous diffuse brain and LM. Whole-brain radiotherapy with concurrent afatinib resulted in an almost complete regression of neurological symptoms as well as good, durable radiological response...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28540225/testosterone-deficiency-in-adults-and-corresponding-treatment-patterns-across-the-globe
#19
REVIEW
James Anaissie, Kent J DeLay, William Wang, Georgios Hatzichristodoulou, Wayne J Hellstrom
The global prevalence of testosterone deficiency (TD) ranges from 10-40%. The actual diagnosis of TD is controversial, as a wide range of total testosterone (TT) thresholds are used for diagnosis (200-400 ng/dL), and physicians differ in their emphasis placed on clinical symptoms. There are also significant global differences in the prescription patterns of testosterone replacement therapy (TRT). In the United States, prescription of TRT is significantly higher than the rest of the world, increasing 3-fold over the last 10 years and more so in eugonadal men...
April 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28538391/evidence-of-elemene-injection-combined-radiotherapy-in-lung-cancer-treatment-among-patients-with-brain-metastases-a-systematic-review-and-meta-analysis
#20
Xutao Jiang, Tesfaldet Habtemariam Hidru, Zhuo Zhang, Yu Bai, Lingchao Kong, Xiaofeng Li
BACKGROUND: This review evaluates the effectiveness and safety of elemene injection combined radiotherapy in the treatment of lung cancer with brain metastases. METHODS: A systematic literature research was conducted from EMBASE, Cochrane Library, PubMed, Chinese biomedical database, Chinese scientific journal database, China knowledge resource integrated database, and WanFang Database from established to July 2016 without language restriction. The Cochrane Collaboration tool was used to evaluate the risk of bias...
May 2017: Medicine (Baltimore)
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