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Diagnostic tests for fibromyalgia

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https://www.readbyqxmd.com/read/28275316/cohort-description-the-danish-study-of-functional-disorders
#1
Thomas Meinertz Dantoft, Jeanette Frost Ebstrup, Allan Linneberg, Sine Skovbjerg, Anja Lykke Madsen, Jesper Mehlsen, Louise Brinth, Lene Falgaard Eplov, Tina Wisbech Carstensen, Andreas Schroder, Per Klausen Fink, Erik Lykke Mortensen, Torben Hansen, Oluf Pedersen, Torben Jørgensen
The Danish study of Functional Disorders (DanFunD) cohort was initiated to outline the epidemiology of functional somatic syndromes (FSS) and is the first larger coordinated epidemiological study focusing exclusively on FSS. FSS are prevalent in all medical settings and can be defined as syndromes that, after appropriate medical assessment, cannot be explained in terms of a conventional medical or surgical disease. FSS are frequent and the clinical importance varies from vague symptoms to extreme disability...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28265170/reliability-and-validity-of-the-turkish-version-of-the-fibromyalgia-rapid-screening-tool-first
#2
Reyhan Celiker, Lale Altan, Aylin Rezvani, Ilknur Aktas, Nurettin Tastekin, Erbil Dursun, Nigar Dursun, Selda Sarıkaya, Senay Ozdolap, Kenan Akgun, Coskun Zateri, Murat Birtane
[Purpose] An easy-to-use, psychometrically validated screening tool for fibromyalgia is needed. This study aims to evaluate the reliability and validity of the Turkish version of the Fibromyalgia Rapid Screening Tool by correlating it with 2013 American College of Rheumatology alternative diagnostic criteria and the Hospital Anxiety and Depression Scale. [Subjects and Methods] Subjects were 269 Physical Medicine and Rehabilitation clinic outpatients. Patients completed a questionnaire including the Fibromyalgia Rapid Screening Tool (twice), 2013 American College of Rheumatology alternative diagnostic criteria, and the Hospital Anxiety and Depression Scale...
February 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28239223/exercise-reduces-depressive-symptoms-in-adults-with-arthritis-evidential-value
#3
George A Kelley, Kristi S Kelley
PURPOSE: Determine whether evidential value exists that exercise reduces depressive symptoms in adults with arthritis and other rheumatic diseases. METHODS: Using data from a previous meta-analysis of 29 published studies that included 2449 participants (1470 exercise, 979 control) with fibromyalgia, osteoarthritis, rheumatoid arthritis or systemic lupus erythematosus, a novel, recently developed method, p-curve, was used to assess for evidential value and rule out selective reporting of statistically significant findings regarding exercise and depressive symptoms in adults with arthritis and other rheumatic diseases...
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28229811/patient-phenotypes-in-fibromyalgia-comorbid-with-systemic-sclerosis-or-rheumatoid-arthritis-influence-of-diagnostic-and-screening-tests-screening-with-the-first-questionnaire-diagnosis-with-the-acr1990-and-revised-acr-2010-criteria
#4
Serge Perrot, Mariana Peixoto, Philippe Dieudé, Eric Hachulla, Jerome Avouac, Sebastien Ottaviani, Yannick Allanore
OBJECTIVES: Fibromyalgia (FM) may occur with rheumatoid arthritis (RA) and systemic sclerosis (SSc), and debate remains about its diagnosis. We aimed to use three FM tools (a screening tool (FiRST), diagnostic criteria (ACR 1990 and revised 2010), to compare FM prevalence between RA and SSc patients, to describe the phenotypes of patients with comorbid FM, and to analyze links between FM and secondary Sjögren's syndrome (SS). METHODS: Consecutive adult patients with confirmed RA or SSc from four university hospitals were tested with the three FM tools...
February 8, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28123865/automated-quantitation-of-cold-inducible-human-brown-adipose-tissue-with-fdg-pet-ct-with-application-to-fibromyalgia
#5
José V Pardo, Joel T Lee, Robert C Larson, Paul Thuras, Alice A Larson
Increasing recognition of the importance of brown adipose tissue (BAT) motivates the development of reproducible and quantitative methods for measuring it. Positron emission tomography (PET)/computerized tomography (CT) with (18)F-fluorodeoxyglucose (FDG) has become the principal method to non-invasively detect brown adipose tissue (BAT) in humans. Improvements in quantitation and standardization will drive further clinical application. One disorder hypothesized to involve dysregulation in thermoregulation and the processing of pain involving BAT is fibromyalgia syndrome (FMS)...
2017: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28075425/management-of-fibromyalgia-practical-guides-from-recent-evidence-based-guidelines
#6
Winfried Häuser, Jacob Ablin, Serge Perrot, Mary-Ann Fitzcharles
Fibromyalgia (FM) is a prevalent and costly condition worldwide, affecting approximately 2% of the general population. Recent evidence- and consensus‑based guidelines from Canada, Germany, Israel, and the European League Against Rheumatism aim to support physicians in achieving a comprehensive diagnostic workup of patients with chronic widespread (generalized) pain (CWP) and to assist patients and physicians in shared decision making on treatment options. Every patient with CWP requires, at the first medical evaluation, a complete history, medical examination, and some laboratory tests (complete blood count, measurement of C‑reactive protein, serum calcium, creatine phosphokinase, thyroid‑stimulating hormone, and 25‑hydroxyvitamin D levels) to screen for metabolic or inflammatory causes of CWP...
January 4, 2017: Pol Arch Intern Med
https://www.readbyqxmd.com/read/27644428/piriformis-syndrome-a-case-series-of-31-bangladeshi-people-with-literature-review
#7
Md Abu Bakar Siddiq, Md Shawkat Hossain, Mohammad Moin Uddin, Israt Jahan, Moshiur Rahman Khasru, Neaz Mahmud Haider, Johannes J Rasker
AIMS: To describe a series of piriformis syndrome patient among Bangladesh people with literature review. METHODS: Consecutive 31 piriformis syndrome patients were enrolled. Besides history and clinical examination, piriformis muscle thickness was also measured with diagnostic ultrasound (3.5 MHZ). MRI of lumbar spine, X-rays of lumbo-sacral spine, and pelvis were performed in all patients. Statistical Package for the Social Sciences (SPSS), Windows 8.0, was used for statistical calculation, and univariate analysis of primary data was done...
February 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/27583141/magnitude-and-variability-of-effect-sizes-for-the-associations-between-chronic-pain-and-cognitive-test-performances-a-meta-analysis
#8
Michél Rathbone, William Parkinson, Yasir Rehman, Shucui Jiang, Mohit Bhandari, Dinesh Kumbhare
OBJECTIVES AND METHODS: A systematic review and meta-analysis were performed to estimate the size and variability of the association between chronic pain (CP) and poorer cognitive test performances as a function of individual tests, pain sub-types, and study sources on 22 studies having (1) a control group, (2) reported means and standard deviations (SDs) and (3) tests studied at least 3 times. RESULTS: CP patients performed significantly poorer with small to moderate effects (d = -...
August 2016: British Journal of Pain
https://www.readbyqxmd.com/read/27553896/painful-temporomandibular-disorders-and-central-sensitization-implications-for-management-a-pilot-study
#9
L B Campi, P C Jordani, H L Tenan, C M Camparis, D A G Gonçalves
The objective was to investigate the presence of cutaneous allodynia and hyperalgesia in the trigeminal and extra-trigeminal areas, as a surrogate for central sensitization (CS), in women with a painful temporomandibular disorder (TMD) and without other painful conditions. Painful TMDs, depression, and non-specific physical symptoms (NSPS) were classified according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). The amount of pain in the trigeminal and extra-trigeminal areas was determined using a visual analogue scale (0-100mm) after the application of a vibrotactile stimulus and assessment of the pressure pain threshold (PPT)...
January 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27489782/exercise-reduces-depressive-symptoms-in-adults-with-arthritis-evidential-value
#10
George A Kelley, Kristi S Kelley
AIM: To determine whether evidential value exists that exercise reduces depression in adults with arthritis and other rheumatic conditions. METHODS: Utilizing data derived from a prior meta-analysis of 29 randomized controlled trials comprising 2449 participants (1470 exercise, 979 control) with fibromyalgia, osteoarthritis, rheumatoid arthritis or systemic lupus erythematosus, a new method, P-curve, was utilized to assess for evidentiary worth as well as dismiss the possibility of discriminating reporting of statistically significant results regarding exercise and depression in adults with arthritis and other rheumatic conditions...
July 12, 2016: World Journal of Rheumatology
https://www.readbyqxmd.com/read/27473633/morning-versus-evening-bright-light-treatment-at-home-to-improve-function-and-pain-sensitivity-for-women-with-fibromyalgia-a-pilot-study
#11
Helen J Burgess, Margaret Park, Jason C Ong, Najia Shakoor, David A Williams, John Burns
OBJECTIVE: To test the feasibility, acceptability, and effects of a home-based morning versus evening bright light treatment on function and pain sensitivity in women with fibromyalgia. DESIGN: A single blind randomized study with two treatment arms: 6 days of a 1 hour morning light treatment or 6 days of a 1 hour evening light treatment. Function, pain sensitivity, and circadian timing were assessed before and after treatment. SETTING: Participants slept at home, except for two nights in Sleep Center...
July 29, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/27157394/genome-wide-expression-profiling-in-the-peripheral-blood-of-patients-with-fibromyalgia
#12
Kim D Jones, Terri Gelbart, Thomas C Whisenant, Jill Waalen, Tony S Mondala, David N Iklé, Daniel R Salomon, Robert M Bennett, Sunil M Kurian
OBJECTIVES: Fibromyalgia (FM) is a common pain disorder characterized by nociceptive dysregulation. The basic biology of FM is poorly understood. Herein we have used agnostic gene expression as a potential probe for informing its underlying biology and the development of a proof-of-concept diagnostic gene expression signature. METHODS: We analyzed RNA expression in 70 FM patients and 70 healthy controls. The isolated RNA was amplified and hybridized to Affymetrix® Human Gene 1...
March 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27132119/no-relevant-excess-prevalence-of-myotonic-dystrophy-type-2-in-patients-with-suspected-fibromyalgia-syndrome
#13
J van Vliet, A Verrips, A A Tieleman, H Scheffer, H A Cats, A A den Broeder, B G M van Engelen
Myotonic dystrophy type 2 (DM2) is a rare, autosomal dominant, multisystem disorder with proximal weakness, myotonia, pain and cataract as important symptoms. Given the assumed underreporting of DM2 in the Netherlands combined with the predominant role of pain in DM2 as well as in fibromyalgia syndrome (FMS), we hypothesized there will be an excess prevalence of DM2 in patients with (suspected) FMS. Our objective was to determine the prevalence of DM2 in patients with suspected FMS. A prevalence of 2% was considered a relevant excess frequency...
June 2016: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/26870391/systemic-lupus-erythematosus-and-primary-fibromyalgia-can-be-distinguished-by-testing-for-cell-bound-complement-activation-products
#14
Daniel J Wallace, Stuart L Silverman, John Conklin, Derren Barken, Thierry Dervieux
OBJECTIVE: We sought to establish the performance of cell-bound complement activation products (CB-CAPs) as a diagnostic tool to distinguish primary fibromyalgia (FM) from systemic lupus erythematosus (SLE). METHODS: A total of 75 SLE and 75 primary FM adult subjects who fulfilled appropriate classification criteria were enrolled prospectively. CB-CAPs (erythrocyte-C4d (EC4d) and B-lymphocyte-C4d (BC4d)) were determined by flow cytometry. Antinuclear antibodies (ANAs) were determined using indirect immunofluorescence while other autoantibodies were determined by solid-phase assays...
2016: Lupus Science & Medicine
https://www.readbyqxmd.com/read/26817567/fibromyalgia-management-strategies-for-primary-care-providers
#15
REVIEW
L M Arnold, K B Gebke, E H S Choy
AIMS: Fibromyalgia (FM), a chronic disorder defined by widespread pain, often accompanied by fatigue and sleep disturbance, affects up to one in 20 patients in primary care. Although most patients with FM are managed in primary care, diagnosis and treatment continue to present a challenge, and patients are often referred to specialists. Furthermore, the lack of a clear patient pathway often results in patients being passed from specialist to specialist, exhaustive investigations, prescription of multiple drugs to treat different symptoms, delays in diagnosis, increased disability and increased healthcare resource utilisation...
February 2016: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/26645318/a-study-on-the-effects-of-sympathetic-skin-response-parameters-in-diagnosis-of-fibromyalgia-using-artificial-neural-networks
#16
Ozhan Ozkan, Murat Yildiz, Evren Arslan, Sedat Yildiz, Suleyman Bilgin, Selami Akkus, Hasan R Koyuncuoglu, Etem Koklukaya
Fibromyalgia syndrome (FMS), usually observed commonly in females over age 30, is a rheumatic disease accompanied by extensive chronic pain. In the diagnosis of the disease non-objective psychological tests and physiological tests and laboratory test results are evaluated and clinical experiences stand out. However, these tests are insufficient in differentiating FMS with similar diseases that demonstrate symptoms of extensive pain. Thus, objective tests that would help the diagnosis are needed. This study analyzes the effect of sympathetic skin response (SSR) parameters on the auxiliary tests used in FMS diagnosis, the laboratory tests and physiological tests...
March 2016: Journal of Medical Systems
https://www.readbyqxmd.com/read/26520483/investigation-of-the-relationship-between-anxiety-and-heart-rate-variability-in-fibromyalgia-a-new-quantitative-approach-to-evaluate-anxiety-level-in-fibromyalgia-syndrome
#17
Suleyman Bilgin, Evren Arslan, Onur Elmas, Sedat Yildiz, Omer H Colak, Gurkan Bilgin, Hasan Rifat Koyuncuoglu, Selami Akkus, Selcuk Comlekci, Etem Koklukaya
BACKGROUND: Fibromyalgia syndrome (FMS) is identified by widespread musculoskeletal pain, sleep disturbance, nonrestorative sleep, fatigue, morning stiffness and anxiety. Anxiety is very common in Fibromyalgia and generally leads to a misdiagnosis. Self-rated Beck Anxiety Inventory (BAI) and doctor-rated Hamilton Anxiety Inventory (HAM-A) are frequently used by specialists to determine anxiety that accompanies fibromyalgia. However, these semi-quantitative anxiety tests are still subjective as the tests are scored using doctor-rated or self-rated scales...
December 1, 2015: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/26492963/influenza-vaccination-is-safe-and-effective-in-patients-suffering-from-fibromyalgia-syndrome
#18
J N Ablin, V Aloush, A Brill, M Berman, M Barzilai, D Caspi, M Mandelboim, D Levartovsky, A Polachek, Y Wolman, D Paran, M Barkagan, O Elkayam
The fibromyalgia syndrome (FMS) is considered to result from the exposure of a genetically susceptible individual to various triggers, such as physical trauma, stress, viral infections etc. A possible role of vaccination in FMS etiology has been suspected. Our objective was to evaluate the efficacy and safety of influenza vaccination in FMS patients. Nineteen FMS patients underwent physical and dolorimetric examinations and answered the fibromyalgia impact questionnaire (FIQ), the widespread pain index (WPI) checklist and the symptoms severity scale (SSS), which are part of the 2010 diagnostic criteria...
September 16, 2015: Reumatismo
https://www.readbyqxmd.com/read/26406206/the-reliability-and-validity-of-the-turkish-version-of-fibromyalgia-survey-diagnostic-criteria-and-symptom-severity-scale
#19
Muyesser Nergiz Yanmaz, Sevgi Atar, Mualla Biçer
BACKGROUND: The fibromyalgia survey diagnostic criteria and severity scale (FSDC) is a self-reported version of 2010 preliminary diagnostic criteria for fibromyalgia syndrome (FMS). FSDC not only facilitates to diagnose FMS, it measures pain (the Widespread Pain Index (WPI)/FSDC Section 3), the Symptom Severity (SS)/FSDC Sections 1 and 2, and provides a score, polysymptomatic distress (PSD)/FSDC Total score in patients with FMS. The purpose of our study is to evaluate the reliability and validity of Turkish version of FSDC in Turkish patients with FMS...
April 27, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/26263122/neuropathic-pain-assessment-update-on-laboratory-diagnostic-tools
#20
REVIEW
Tina Mainka, Christoph Maier, Elena K Enax-Krumova
PURPOSE OF REVIEW: The purpose of this review was to provide an update on the diagnostic tools for neuropathic pain for clinical practice. RECENT FINDINGS: The new definition of neuropathic pain by the International Association for the Study of Pain requires confirmation of a lesion or disease affecting the somatosensory system. In addition to traditional diagnostic procedures, for example, nerve conduction studies, skin biopsies depict morphological alteration and/or rarefication of the small intraepidermal nerve fibers and were recently used to identify small fiber abnormalities, for example, in patients with fibromyalgia or sarcoidosis...
October 2015: Current Opinion in Anaesthesiology
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