keyword
MENU ▼
Read by QxMD icon Read
search

image analysis

keyword
https://www.readbyqxmd.com/read/28231626/default-mode-network-deactivation-to-smoking-cue-relative-to-food-cue-predicts-treatment-outcome-in-nicotine-use-disorder
#1
Claire E Wilcox, Eric D Claus, Vince D Calhoun, Srinivas Rachakonda, Rae A Littlewood, Jessica Mickey, Pamela B Arenella, Natalie Goodreau, Kent E Hutchison
Identifying predictors of treatment outcome for nicotine use disorders (NUDs) may help improve efficacy of established treatments, like varenicline. Brain reactivity to drug stimuli predicts relapse risk in nicotine and other substance use disorders in some studies. Activity in the default mode network (DMN) is affected by drug cues and other palatable cues, but its clinical significance is unclear. In this study, 143 individuals with NUD (male n = 91, ages 18-55 years) received a functional magnetic resonance imaging scan during a visual cue task during which they were presented with a series of smoking-related or food-related video clips prior to randomization to treatment with varenicline (n = 80) or placebo...
February 23, 2017: Addiction Biology
https://www.readbyqxmd.com/read/28231577/response-evaluation-in-head-and-neck-oncology-definition-and-prediction
#2
T K Hoffmann, P J Schuler, S Laban, R Grässlin, M Beer, A J Beer, U Friebe-Hoffmann, L Bullinger, P Möller, T Wiegel
Curative treatment of head and neck squamous cell carcinoma includes surgery and/or (chemo)radiation, whereas in the palliative setting, chemotherapy and/or immunotherapy represent(s) the standard approach. With regard to quality control, methods for determining treatment response are sorely needed. For surgical therapy, histopathology is the standard quality control. Established criteria for high-risk patients include resection margins of the primary tumor and extracapsular extension of lymph node metastases...
February 24, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28231575/individual-biomarkers-using-molecular-personalized-medicine-approaches
#3
Hans P Zenner
Molecular personalized medicine tries to generate individual predictive biomarkers to assist doctors in their decision making. These are thought to improve the efficacy and lower the toxicity of a treatment. The molecular basis of the desired high-precision prediction is modern "omex" technologies providing high-throughput bioanalytical methods. These include genomics and epigenomics, transcriptomics, proteomics, metabolomics, microbiomics, imaging, and functional analyses. In most cases, producing big data also requires a complex biomathematical analysis...
February 24, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28231402/ex-vivo-visualization-of-human-ciliated-epithelium-and-quantitative-analysis-of-induced-flow-dynamics-by-using-optical-coherence-tomography
#4
Yuye Ling, Xinwen Yao, Ute A Gamm, Emilio Arteaga-Solis, Charles W Emala, Michael A Choma, Christine P Hendon
BACKGROUND AND OBJECTIVE: Cilia-driven mucociliary clearance is an important self-defense mechanism of great clinical importance in pulmonary research. Conventional light microscopy possesses the capability to visualize individual cilia and its beating pattern but lacks the throughput to assess the global ciliary activities and flow dynamics. Optical coherence tomography (OCT), which provides depth-resolved cross-sectional images, was recently introduced to this area. MATERIALS AND METHODS: Fourteen de-identified human tracheobronchial tissues are directly imaged by two OCT systems: one system centered at 1,300 nm with 6...
February 23, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28231395/functional-connectivity-in-amygdalar-sensory-pre-motor-networks-at-rest-new-evidence-from-the-human-connectome-project
#5
Nicola Toschi, Andrea Duggento, Luca Passamonti
The word "e-motion" derives from the Latin word "ex-moveo" which literally means "moving away from something / somebody". Emotions are thus fundamental to prime action and goal-directed behavior with obvious implications for individual's survival. However, the brain mechanisms underlying the interactions between emotional and motor cortical systems remain poorly understood. A recent diffusion tensor imaging study in humans has reported the existence of direct anatomical connections between the amygdala and sensory/(pre)motor cortices, corroborating an initial observation in animal research...
February 23, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28231370/significance-of-imaging-in-the-diagnosis-of-olfactory-disorder
#6
Teemu Harju, Markus Rautiainen, Ilkka Kivekäs
The aim of this retrospective analysis was to examine olfactory disorders among the patients in the Ear, Nose, and Throat Clinic of Tampere University Hospital, Finland, from 2001 to 2011, and to evaluate the necessity of imaging in the examination of patients with olfactory disorders. Charts of 143 consecutive patients with a primary olfactory disorder were examined, and 69 patients who had undergone the necessary testing were included in the study. The most common causes of olfactory disorder were upper respiratory infection (23%), chronic rhinosinusitis (19%), head trauma (17%), and allergic or nonallergic rhinitis (6%)...
February 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28231342/nonlinear-image-registration-with-bidirectional-metric-and-reciprocal-regularization
#7
Shihui Ying, Dan Li, Bin Xiao, Yaxin Peng, Shaoyi Du, Meifeng Xu
Nonlinear registration is an important technique to align two different images and widely applied in medical image analysis. In this paper, we develop a novel nonlinear registration framework based on the diffeomorphic demons, where a reciprocal regularizer is introduced to assume that the deformation between two images is an exact diffeomorphism. In detail, first, we adopt a bidirectional metric to improve the symmetry of the energy functional, whose variables are two reciprocal deformations. Secondly, we slack these two deformations into two independent variables and introduce a reciprocal regularizer to assure the deformations being the exact diffeomorphism...
2017: PloS One
https://www.readbyqxmd.com/read/28231293/photoacoustic-imaging-features-of-intraocular-tumors-retinoblastoma-and-uveal-melanoma
#8
Guan Xu, Yafang Xue, Zeynep Gürsel Özkurt, Naziha Slimani, Zizhong Hu, Xueding Wang, Kewen Xia, Teng Ma, Qifa Zhou, Hakan Demirci
The purpose of this study is to examine the capability of photoacoustic (PA) imaging (PAI) in assessing the unique molecular and architectural features in ocular tumors. A real-time PA and ultrasonography (US) parallel imaging system based on a research US platform was developed to examine retinoblastoma in mice in vivo and human retinoblastoma and uveal melanoma ex vivo. PA signals were generated by optical illumination at 720, 750, 800, 850, 900 and 950 nm delivered through a fiber optical bundle. The optical absorption spectra of the tumors were derived from the PA images...
2017: PloS One
https://www.readbyqxmd.com/read/28231282/mindboggling-morphometry-of-human-brains
#9
Arno Klein, Satrajit S Ghosh, Forrest S Bao, Joachim Giard, Yrjö Häme, Eliezer Stavsky, Noah Lee, Brian Rossa, Martin Reuter, Elias Chaibub Neto, Anisha Keshavan
Mindboggle (http://mindboggle.info) is an open source brain morphometry platform that takes in preprocessed T1-weighted MRI data and outputs volume, surface, and tabular data containing label, feature, and shape information for further analysis. In this article, we document the software and demonstrate its use in studies of shape variation in healthy and diseased humans. The number of different shape measures and the size of the populations make this the largest and most detailed shape analysis of human brains ever conducted...
February 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28231035/biologically-relevant-heterogeneity-metrics-and-practical-insights
#10
Albert Gough, Andrew M Stern, John Maier, Timothy Lezon, Tong-Ying Shun, Chakra Chennubhotla, Mark E Schurdak, Steven A Haney, D Lansing Taylor
Heterogeneity is a fundamental property of biological systems at all scales that must be addressed in a wide range of biomedical applications, including basic biomedical research, drug discovery, diagnostics, and the implementation of precision medicine. There are a number of published approaches to characterizing heterogeneity in cells in vitro and in tissue sections. However, there are no generally accepted approaches for the detection and quantitation of heterogeneity that can be applied in a relatively high-throughput workflow...
March 2017: SLAS Discov
https://www.readbyqxmd.com/read/28230716/experimental-texture-analysis-in-glioblastoma-a-methodological-study
#11
Nicolin Hainc, Christoph Stippich, Bram Stieltjes, Severina Leu, Andrea Bink
OBJECTIVES: Analysis of a single slice of a tumor to extract biomarkers for texture analysis may result in loss of information. We investigated correlation of fractional volumes to entire tumor volumes and introduced expanded regions of interest (ROIs) outside the visual tumor borders in glioblastoma. MATERIALS AND METHODS: Retrospective slice-by-slice volumetric texture analysis on 46 brain magnetic resonance imaging subjects with histologically confirmed glioblastoma was performed...
February 22, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28230650/acr-appropriateness-criteria%C3%A2-resectable-pancreatic-cancer
#12
William E Jones, W Waren Suh, May Abdel-Wahab, Ross A Abrams, Nilofer Azad, Prajnan Das, Jadranka Dragovic, Karyn A Goodman, Salma K Jabbour, Andre A Konski, Albert C Koong, Rachit Kumar, Percy Lee, Timothy M Pawlik, William Small, Joseph M Herman
Management of resectable pancreatic adenocarcinoma continues to present a challenge due to a paucity of high-quality randomized studies. Administration of adjuvant chemotherapy is widely accepted due to the high risk of systemic spread associated with pancreatic adenocarcinoma, but the role of radiation therapy is less clear. This paper reviews literature associated with resectable pancreatic cancer to include prognostic factors to aid in the selection of patients appropriate for adjuvant therapies. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel...
February 22, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28230596/the-efficacy-of-immediate-implant-placement-in-extraction-sockets-for-alveolar-bone-preservation-a-clinical-evaluation-using-three-dimensional-cone-beam-computerized-tomography-and-resonance-frequency-analysis-value
#13
Ali Al Qabbani, Noor Hayati A Razak, Sausan Al Kawas, Suzina Sheikh Abdul Hamid, Saad Wahbi, A R Samsudin
The aim of this study was to determine the efficacy of immediate implant placement with alveolar bone augmentation on socket preservation following atraumatic tooth extraction and comparing it with a tooth alveolar socket that was allowed to heal in a conventional way.Twenty medically fit patients (8 males and 12 females aged between 18 and 40 years) who needed noncomplicated tooth extraction of mandibular premolar teeth were divided randomly and equally into 2 groups. In Group I, the empty extraction socket was left untreated and allowed to heal in a conventional way...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28230594/alveolar-molding-effect-in-infants-with-unilateral-cleft-lip-and-palate-comparison-of-two-and-three-dimensional-measurements
#14
Won Hee Lim, Eun Woo Park, Hwa Sung Chae, Soon Man Kwon, Hoi-In Jung, Seung-Hak Baek
The purpose of this study was to compare the results of two- (2D) and three-dimensional (3D) measurements for the alveolar molding effect in patients with unilateral cleft lip and palate. The sample consisted of 23 unilateral cleft lip and palate infants treated with nasoalveolar molding (NAM) appliance. Dental models were fabricated at initial visit (T0; mean age, 23.5 days after birth) and after alveolar molding therapy (T1; mean duration, 83 days). For 3D measurement, virtual models were constructed using a laser scanner and 3D software...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28230253/risk-of-vigabatrin-associated-brain-abnormalities-on-mri-in-the-treatment-of-infantile-spasms-is-dose-dependent
#15
Shaun A Hussain, Jackie Tsao, Menglu Li, Madeline D Schwarz, Raymond Zhou, Joyce Y Wu, Noriko Salamon, Raman Sankar
OBJECTIVE: Although the link between vigabatrin (VGB) and retinotoxicity is well known, little attention has been focused on the risk of VGB-associated brain abnormalities on magnetic resonance imaging (MRI) (VABAM), namely reversible-and largely asymptomatic-signal changes in the thalami, basal ganglia, brainstem tegmentum, and cerebellar nuclei. Using a large infantile spasms cohort, we set out to identify predictors of these phenomena. METHODS: Children with infantile spasms were retrospectively identified...
February 23, 2017: Epilepsia
https://www.readbyqxmd.com/read/28230188/3d-time-lapse-imaging-and-quantification-of-mitochondrial-dynamics
#16
Miguel Sison, Sabyasachi Chakrabortty, Jérôme Extermann, Amir Nahas, Paul James Marchand, Antonio Lopez, Tanja Weil, Theo Lasser
We present a 3D time-lapse imaging method for monitoring mitochondrial dynamics in living HeLa cells based on photothermal optical coherence microscopy and using novel surface functionalization of gold nanoparticles. The biocompatible protein-based biopolymer coating contains multiple functional groups which impart better cellular uptake and mitochondria targeting efficiency. The high stability of the gold nanoparticles allows continuous imaging over an extended time up to 3000 seconds without significant cell damage...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28230179/crowdsourcing-scoring-of-immunohistochemistry-images-evaluating-performance-of-the-crowd-and-an-automated-computational-method
#17
Humayun Irshad, Eun-Yeong Oh, Daniel Schmolze, Liza M Quintana, Laura Collins, Rulla M Tamimi, Andrew H Beck
The assessment of protein expression in immunohistochemistry (IHC) images provides important diagnostic, prognostic and predictive information for guiding cancer diagnosis and therapy. Manual scoring of IHC images represents a logistical challenge, as the process is labor intensive and time consuming. Since the last decade, computational methods have been developed to enable the application of quantitative methods for the analysis and interpretation of protein expression in IHC images. These methods have not yet replaced manual scoring for the assessment of IHC in the majority of diagnostic laboratories and in many large-scale research studies...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28230026/the-diagnostic-value-of-contrast-enhanced-computed-tomography-imaging-for-detection-of-colorectal-tumors-a-meta-analysis
#18
Qing Yu, Jie Liu
OBJECTIVE: To evaluate the application usage of contrast-enhanced computer tomography imaging for colorectal tumors diagnosis. METHODS: By searching the Medline and CNKI databases, we collected all diagnostic tests about contrast-enhanced CT imaging for colorectal tumors. Sensitivity and specificity were calculated to evaluate the usage of individual diagnostic tests. The data were analyzed using statistic software Meta-DiSc 1.4. RESULTS: Nine trials that included a total of 4797 patients were analyzed in this study...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28230009/effect-of-heat-sink-on-the-recurrence-of-small-malignant-hepatic-tumors-after-radiofrequency-ablation
#19
Zheng-Yu Lin, Guo-Lin Li, Jin Chen, Zhong-Wu Chen, Yi-Ping Chen, Sun-Zhi Lin
AIMS: The aim of this study was to investigate the effect of heat sink on the recurrence of hepatic malignant tumors <3 cm after percutaneous radiofrequency ablation (RFA). SUBJECTS AND METHODS: This study included 564 hepatic malignant tumors <3 cm in 381 patients. Preoperative images were used to determine whether these tumors were adjacent to vessels, and the diameter of adjacent vessels was measured. RFA was performed computed tomography (CT), magnetic resonance imaging (MRI) and ultrasound (US) guidance, and postoperative imaging follow-up was then conducted...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28229621/caveolin-1-expression-favors-tumor-growth-and-is-associated-with-poor-survival-in-primary-lung-adenocarcinomas
#20
Eleonora Duregon, Rebecca Senetta, Luca Bertero, Benedetta Bussolati, Laura Annaratone, Alessandra Pittaro, Mauro Papotti, Caterina Marchiò, Paola Cassoni
Despite the consolidated clinico-pathological correlates of Caveolin 1 expression in non-small cell lung cancer, the available data on the role of Caveolin 1 in relation to proliferation, migration, and metastasis in lung adenocarcinoma cells is still scant. Here, we aimed to confirm whether Caveolin 1 may act as a promoter of cell growth in human lung adenocarcinoma using in vitro and in vivo models, supported by a survival analysis of Caveolin 1 expression in a series of 116 primary lung adenocarcinomas. The silencing of endogenous Caveolin 1 expression in H522 lung adenocarcinoma cells through stable shRNA transfection significantly inhibited cellular proliferation in vitro and in vivo, in a lung adenocarcinoma xenograft mouse model...
February 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
keyword
keyword
60820
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"