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https://www.readbyqxmd.com/read/29774712/-diagnostic-imaging-procedures-and-prescribing-appropriateness-are-administrative-data-a-proper-instrument-an-experience-from-piedmont-region-northern-italy
#1
Eva Pagano, Laura Crosetto, Andrea Evangelista, Chiara Monagheddu, Ottavio Davini, Giulio Fornero, Ida Raciti, Guido Giustetto, Giovannino Ciccone
OBJECTIVES: to assess at population level if healthcare administrative data can be suitable to identify variability and determinants of the prescribing rates for some diagnostic imaging procedures at high-risk of inappropriateness. DESIGN: population-based observational study. SETTING AND PARTICIPANTS: Piedmont Region (Northern Italy) adult population (>20 years) in year 2013. The subjects included were 3,566,147, referring to 3,016 general practitioners (GPs), in 12 Local Health Authorities (LHAs)...
March 2018: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/29768347/a-retrospective-study-of-alendronate-for-the-treatment-of-ankylosing-spondylitis
#2
Gang Li, Chang-An Lv, Li Tian, Lian-Jin Jin, Wei Zhao
This retrospective study assessed the effect of alendronate for treating patients with ankylosing spondylitis (AS).Eighty-six patients with AS were included in this retrospective study, and were divided into 2 groups. Forty-six patients in the intervention group received alendronate plus vitamin D (400 mg/day) and calcium (500 mg/day), while 40 patients in the control group received vitamin D and calcium only, the same dose as the intervention group. The primary outcome included bone densitometry. The secondary outcomes consisted of quality of life, measured by Ankylosing Spondylitis Quality of Life (ASQoL) questionnaire, disease activity, measured by Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), and functional status, measured by Bath Ankylosing Spondylitis Functional Index (BASFI), as well as the adverse events (AEs)...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29754949/interpretation-of-dual-energy-x-ray-absorptiometry-derived-body-composition-change-in-athletes-a-review-and-recommendations-for-best-practice
#3
REVIEW
Karen Hind, Gary Slater, Brian Oldroyd, Matthew Lees, Shane Thurlow, Matthew Barlow, John Shepherd
Dual-energy X-ray absorptiometry (DXA) is a medical imaging device which has become the method of choice for the measurement of body composition in athletes. The objectives of this review were to evaluate published longitudinal DXA body composition studies in athletic populations for interpretation of "meaningful" change, and to propose a best practice measurement protocol. An online search of PubMed and CINAHL via EBSCO Host and Web of Science enabled the identification of studies published until November 2016...
March 23, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29753150/identification-of-asymptomatic-frailty-vertebral-fractures-in-post-menopausal-women
#4
S Pizzato, C Trevisan, P Lucato, G Girotti, M Mazzochin, B M Zanforlini, G Bano, F Piovesan, A Bertocco, F Zoccarato, M Dianin, E Manzato, G Sergi
PURPOSE: Vertebral fractures are associated with persistent pain, disability and mortality. However, around two thirds of women with vertebral fractures are unaware of them. We aimed to analyze which factors could mostly be associated to the presence of vertebral fractures in post-menopausal women, and evaluate the effectiveness of current screening criteria for the detection of vertebral fractures in an outpatient setting. METHODS: We evaluated 1132 post-menopausal women referred to the osteoporosis outpatient clinic of the Geriatrics Department of Padova...
May 9, 2018: Bone
https://www.readbyqxmd.com/read/29748870/fructan-enriched-diet-increases-bone-quality-in-female-growing-rats-at-calcium-deficiency
#5
Kinga Topolska, Radosław Piotr Radzki, Agnieszka Filipiak-Florkiewicz, Adam Florkiewicz, Teresa Leszczyńska, Ewa Cieślik
This study was designed to determine the effect of feeding female rats with low-calcium diet containing one of three fructan sources (Jerusalem artichoke, yacon, Beneo Orafti Synergy1), on selected bone parameters. Growing Wistar rats were fed modified AIN-93 G diet enriched in fructan sources (8%), added alone or as a strawberry sorbet ingredient. Two of eight groups were a validation model, where the positive control group was fed with recommended calcium dose in the diet (RCD), and negative one - with low calcium diet (LCD)...
May 10, 2018: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/29748651/advances-in-assessing-body-composition-during-pregnancy
#6
REVIEW
Jasper Most, Kara Lynn Marlatt, Abby Duhé Altazan, Leanne Maree Redman
The prevalence of excess gestational weight gain is increasing worldwide and is associated with pregnancy complications, including gestational diabetes mellitus, pre-eclampsia, preterm birth, macrosomia, and development of obesity in offspring. Whereas gestational weight gain positively correlates with the gain in fat mass (FM), fat-free mass (FFM) gain is relatively consistent across pregnancies. Commonly used methods to assess body composition include anthropometry, densitometry (air displacement plethysmography, underwater weighing), and hydrometry (isotope dilution, bioimpedance analysis)...
May 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29737798/malnutrition-and-chronic-inflammation-as-risk-factors-for-sarcopenia-in-elderly-patients-with-hip-fracture
#7
Jun-Il Yoo, Yong-Chan Ha, Hana Choi, Kyu-Hwang Kim, Young-Kyun Lee, Kyung-Hoi Koo, Ki-Soo Park
BACKGROUND AND OBJECTIVES: To evaluate malnutrition and chronic inflammation as risk factors for sarcopenia in elderly patients with hip fractures, as defined by the criteria of the Asian Working Group on Sarcopenia (AWGS). METHODS AND STUDY DESIGN: A total of 327 elderly patients with hip fractures were enrolled in this retrospective observational study. The main outcome measure was the nutritional status and nutritional risk factors for sarcopenia in elderly patients...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29730856/comparison-of-densitometric-profile-after-deep-lamellar-keratoplasty-with-two-different-techniques-for-treatment-of-keratoconus
#8
Mohammad Ghoreishi, Abolfazl Kashfi, Mohammadreza Peyman, Shahriar Hanjani, Mohaddese Mohammadinia, Mike Straiko
PURPOSE: To compare densitometric outcome of two techniques of deep lamellar keratoplasty using Pentacam HR corneal densitometry software. METHODS: Postoperative outcomes of 31 patients with big bubble (BB) and 28 patients with Melles (M) surgery for the treatment of keratoconus were evaluated. Data were gathered at least 3 months after the removal of all sutures including demographic data, uncorrected distance visual acuity (UCDVA), best spectacle-corrected visual acuity (BSCVA), refraction and endothelial cell count...
May 5, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29719653/scheimpflug-based-optical-densitometry-for-assessment-of-corneal-opacity-an-objective-method-to-monitor-interstitial-keratitis
#9
Alireza Peyman, Mohsen Pourazizi
No abstract text is available yet for this article.
April 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29703451/osteoporosis-bone-mineral-density-and-ckd-mbd-complex-i-diagnostic-considerations
#10
Jordi Bover, Pablo Ureña-Torres, Josep-Vicent Torregrosa, Minerva Rodríguez-García, Cristina Castro-Alonso, José Luis Górriz, Ana María Laiz Alonso, Secundino Cigarrán, Silvia Benito, Víctor López-Báez, María Jesús Lloret Cora, Iara daSilva, Jorge Cannata-Andía
Osteoporosis (OP) and chronic kidney disease (CKD) independently influence bone and cardiovascular health. A considerable number of patients with CKD, especially those with stages 3a to 5D, have a significantly reduced bone mineral density leading to a high risk of fracture and a significant increase in associated morbidity and mortality. Independently of classic OP related to age and/or gender, the mechanical properties of bone are also affected by inherent risk factors for CKD ("uraemic OP"). In the first part of this review, we will analyse the general concepts regarding bone mineral density, OP and fractures, which have been largely undervalued until now by nephrologists due to the lack of evidence and diagnostic difficulties in the context of CKD...
April 24, 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29694389/site-specific-glycosaminoglycan-content-is-better-maintained-in-the-pericellular-matrix-than-the-extracellular-matrix-in-early-post-traumatic-osteoarthritis
#11
Simo P Ojanen, Mikko A J Finnilä, Aino E Reunamo, Ari P Ronkainen, Santtu Mikkonen, Walter Herzog, Simo Saarakkala, Rami K Korhonen
INTRODUCTION: One of the characteristics of early osteoarthritis (OA) is the loss of fixed charged density (FCD) of glycosaminoglycans in the superficial zone of articular cartilage. However, possible local changes in the FCD content of the pericellular matrix (PCM) are not fully understood. Hence, our aim was to investigate the effect of unilateral anterior cruciate ligament transection (ACLT) in rabbit knees on estimated FCD in the PCM compared to that in the ECM, and relate these results with cell morphology...
2018: PloS One
https://www.readbyqxmd.com/read/29693762/growth-body-composition-and-bone-density-following-pediatric-liver-transplantation
#12
Amin Sheikh, Tim Cundy, Helen Maria Evans
Patients transplanted for cholestatic liver disease are often significantly fat-soluble vitamin deficient and malnourished pretransplant, with significant corticosteroid exposure post-transplant, with increasing evidence of obesity and metabolic syndrome post-LT. Our study aimed to assess growth, body composition, and BMD in patients post-pediatric LT. Body composition and bone densitometry scans were performed on 21 patients. Pre- and post-transplant anthropometric data were analyzed. Bone health was assessed using serum ALP, calcium, phosphate, and procollagen-1-N-peptide levels...
April 24, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29685130/cataract-surgery-in-patients-with-corneal-opacities
#13
Yi-Ju Ho, Chi-Chin Sun, Hung-Chi Chen
BACKGROUND: Investigating the efficacy and safety of phacoemulsification with intraocular lens (IOL) implantation in corneal opacities. METHODS: This retrospective study was conducted in a tertiary medical center. Twenty-three eyes of 19 patients with cataracts and corneal opacities obscuring the pupillary center having received phacoemulsification with IOL insertion without any ancillary techniques were enrolled. The primary study outcome measures were uncorrected and best corrected visual acuity (BCVA), and complications...
April 23, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29683852/reversing-interferon-alpha-neurotoxicity-in-a-hiv-associated-neurocognitive-disorders-mouse-model
#14
Rajeth Koneru, Heather Bimonte-Nelson, Vincent Ciavatta, Woldeab Haile, Kate Elmore, Jennifer Ward, Leonard Maroun, William R Tyor
OBJECTIVE: Increased brain interferon-alpha (IFNα) is associated with neurodegenerative disorders, including HIV-associated neurocognitive disorders (HAND). HAND occurs in approximately 50% of individuals with HIV despite combined antiretroviral therapy (cART). Therefore, adjunctive therapies must be developed that prevent progression of mild forms of HAND to HIV-associated dementia. Increased IFNα in the CNS has been associated with HAND in patients and in a HAND mouse model. DESIGN AND METHODS: B18R binds IFNα and ameliorates HAND mouse brain histopathology (HIV encephalitis)...
April 19, 2018: AIDS
https://www.readbyqxmd.com/read/29681835/diagnostic-and-management-tool-for-monitoring-patients-implanted-with-a-shape-changing-corneal-inlay
#15
Ralph Chu, Briana R Lee
We report two cases that underwent corneal inlay implantation under a femtosecond flap. The first case had no complications during the postoperative period. Pentacam maps remained stable over time: corneal densitometry (CD) values had less than 2 units of change across visits up to 3 years. Axial/sagittal topography maps showed a stable Kmax (∼47 D), i.e., less than 1 D change between visits. The second case developed haze at 8 months postoperatively. CD increased by more than 4 units from 3 to 8 M and Kmax increased by 2...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29681439/bone-mineral-density-distribution-curves-in-spanish-adults-with-down-syndrome
#16
Ramón Costa, Alejandra Gullón, Rosa De Miguel, Diego Real de Asúa, Azucena Bautista, Clara García, Carmen Suarez, Santos Castañeda, Fernando Moldenhauer
According to reports from small-sized case series, adults with Down syndrome (DS) appear to have lower bone mineral density (BMD) than the general population. The objective of our study was to further characterize the bone mass acquisition curve in an adult DS population. This is a retrospective study of 297 adults with DS from the Adult Down Syndrome Outpatient Clinic of a tertiary care hospital in Madrid, Spain, who underwent a bone densitometry (Hologic QDR-4500W), for clinical purposes between January 2010 and June 2015...
March 21, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29675381/anterior-and-posterior-capsule-densitometry-levels-after-femtosecond-laser-assisted-cataract-surgery
#17
Txomin Alberdi, Javier Mendicute, Lucía Bascarán, Olatz Barandika, Javier Ruiz-Ederra
AIM: To analyze and compare five different variables over one year follow-up (1wk, 1, 3, 6 and 12mo): anterior capsule (AC), and posterior capsule (PC) area densitometry values, AC and PC linear densitometry values, and AC opening area reduction ratio after femtosecond laser-assisted cataract surgery. METHODS: This was a prospective comparative study. Seventy-one patients underwent femtosecond laser-assisted cataract surgery on single eye between June 2014 and December 2015...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29675043/cardiovascular-risk-factors-after-childhood-cancer-treatment-are-independent-of-the-fto-gene-polymorphism
#18
Małgorzata Sawicka-Żukowska, Maryna Krawczuk-Rybak, Paweł Bernatowicz, Katarzyna Muszyńska-Rosłan, Jerzy Konstantynowicz, Włodzimierz Łuczyński
The study objective was to assess the prevalence of cardiovascular disease risk factors in patients treated for childhood cancer ( N = 101) and to determine the involvement of clinical (cancer type and therapy) and/or genetic ( FTO gene rs9939609 polymorphism) factors. Anthropometric features, laboratory findings, and standardized osteodensitometric indices (fat and lean mass) were considered. Overweight/obesity was found in 17.82% of the patients; however, central adiposity was found in as many as 42.5%. At least one abnormality in lipid metabolism was observed in 35...
2018: International Journal of Endocrinology
https://www.readbyqxmd.com/read/29672430/recovery-of-corneal-clarity-after-dmek-followed-by-rebubbling-versus-uneventful-dmek
#19
Apostolos Lazaridis, Ourania Fydanaki, Eleftherios Giallouros, Ilias Georgalas, George Kymionis, Walter Sekundo, Konstantinos Droutsas
PURPOSE: To evaluate the effect of a single rebubbling procedure after Descemet membrane endothelial keratoplasty (DMEK) on corneal backscatter and endothelial cell loss (ECL). METHODS: Medical records of 130 consecutive DMEK cases (118 patients) were reviewed and 3 groups were formed: group 1 (n = 32), consisting of DMEK cases followed by 1 rebubbling; group 2a (n = 55), including uneventful DMEK cases with complete graft attachment; and group 2b (n = 25), including uneventful DMEK cases with minor peripheral detachment, not requiring rebubbling...
April 19, 2018: Cornea
https://www.readbyqxmd.com/read/29664757/primary-hyperparathyroidism-recent-advances
#20
Marcella D Walker, John P Bilezikian
PURPOSE OF REVIEW: The purpose of this review is to describe recent advances and changes in the evaluation and management of primary hyperparathyroidism (PHPT). RECENT FINDINGS: Although it has long been recognized that asymptomatic PHPT is associated with bone loss, particularly at cortical skeletal sites when evaluated with dual-energy X-ray absorptiometry, new imaging techniques suggest that trabecular skeletal deterioration as well as clinically silent vertebral fractures and nephrolithiasis are common...
April 13, 2018: Current Opinion in Rheumatology
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