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Prostate multiparametric imaging

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https://www.readbyqxmd.com/read/28087898/editorial-comment-to-assessing-clinically-significant-prostate-cancer-diagnostic-properties-of-multiparametric-magnetic-resonance-imaging-compared-to-three-dimensional-transperineal-template-mapping-histopathology
#1
Claudia Kesch, Boris A Hadaschik, Jan P Radtke
No abstract text is available yet for this article.
January 13, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28075651/imaging-characteristics-of-prostate-cancer-patients-who-discontinued-active-surveillance-on-3-t-multiparametric-prostate-mri
#2
David J Habibian, Corinne C Liu, Alex Dao, Kaitlin E Kosinski, Aaron E Katz
OBJECTIVE: Early-stage prostate cancer may be followed with active surveillance to avoid overtreatment. Our institution's active surveillance regimen uses annual MRI in place of serial biopsies, and biopsies are performed only when clinically necessary. The objective of our study was to report the multiparametric MRI characteristics of prostate cancer patients who discontinued active surveillance at our institution after repeat imaging revealed possible evidence of tumor upgrading. MATERIALS AND METHODS: The Department of Urology at Winthrop University Hospital prospectively maintains a database of prostate cancer patients who are monitored with active surveillance...
January 11, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28047097/we-fg-206-09-association-of-prostate-volumes-with-restricted-diffusion-and-prostate-cancer-aggressiveness
#3
Y Tschudi
PURPOSE: To create an automatic workflow for evaluation of thresholds of restricted diffusion, based on Apparent Diffusion Coefficient (ADC) values in multiparametric (mp)MRI of the prostate. To investigate the association of these volumes with biopsy Gleason Score (GS). METHODS: Patients with prostate cancer, imaged on 3T Discovery MR750 (GE, Waukesha, WI) magnet were selected from departmental database based on the presence of mpMRI exam. All subsequent analyses were performed using Java plugins in MIM (MIM, Cleveland, Ohio)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046902/su-d-207a-03-potential-role-of-bold-mri-in-discrimination-of-aggressive-tumor-habitat-in-prostate-cancer
#4
J Ford, C Lopez, Y Tschudi, A Breto, K Padgett, A Pollack, R Stoyanova
PURPOSE: To determine whether blood oxygenation level dependent (BOLD) MRI signal measured in prostate cancer patients, in addition to quantitative diffusion and perfusion parameters from multiparametric (mp)MRI exams, can help discriminate aggressive and/or radioresistant lesions. METHODS: Several ongoing clinical trials in our institution require mpMRI exam to determine eligibility (presence of identifiable tumor lesion on mpMRI) and prostate volumes for dose escalation...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28012730/magnetic-resonance-imaging-of-the-prostate-interpretation-using-the-pi-rads-v2
#5
A Torregrosa Andrés, M Otero García, M Sineiro Galiñanes
OBJECTIVE: Version 2 of the Prostate Imaging and Reporting and Data System (PI-RADS) was developed to help in the detection, location, and characterization of prostate cancer with magnetic resonance imaging (MRI). Its recommendations for standardizing image acquisition parameters aims to reduce variability in the interpretation of MRI studies of the prostate; this approach, together with structured reporting, has the added value of improving communication among radiologists and between radiologists and urologists...
December 21, 2016: Radiología
https://www.readbyqxmd.com/read/28012728/magnetic-resonance-imaging-in-the-new-paradigm-for-the-diagnosis-of-prostate-cancer
#6
J C Vilanova, V Catalá
For various reasons, prostate cancer is a major public health problem. It is a very common cancer, but has a very low mortality rate because it comprises two types of disease: one insignificant, indolent, and much more common, and the other aggressive, significant, and much less common. The routine diagnostic approach to prostate cancer has been systematic blind biopsies, which has low detection rates and might detect low risk, insignificant prostate cancer, leading to overdiagnosis and overtreatment of indolent cancers...
December 21, 2016: Radiología
https://www.readbyqxmd.com/read/28004162/multiparametric-dynamic-contrast-enhanced-ultrasound-imaging-of-prostate-cancer
#7
Rogier R Wildeboer, Arnoud W Postema, Libertario Demi, Maarten P J Kuenen, Hessel Wijkstra, Massimo Mischi
OBJECTIVES: The aim of this study is to improve the accuracy of dynamic contrast-enhanced ultrasound (DCE-US) for prostate cancer (PCa) localization by means of a multiparametric approach. MATERIALS AND METHODS: Thirteen different parameters related to either perfusion or dispersion were extracted pixel-by-pixel from 45 DCE-US recordings in 19 patients referred for radical prostatectomy. Multiparametric maps were retrospectively produced using a Gaussian mixture model algorithm...
December 21, 2016: European Radiology
https://www.readbyqxmd.com/read/28002239/feasibility-of-multiparametric-magnetic-resonance-imaging-of-the-prostate-at-7-t
#8
Miriam W Lagemaat, Bart W J Philips, Eline K Vos, Mark J van Uden, Jurgen J Fütterer, Sjoerd F Jenniskens, Tom W J Scheenen, Marnix C Maas
OBJECTIVES: The aim of this study was to evaluate the technical feasibility of prostate multiparametric magnetic resonance imaging (mpMRI) at a magnetic field strength of 7 T. MATERIALS AND METHODS: In this prospective institutional review board-approved study, 14 patients with biopsy-proven prostate cancer (mean age, 65.2 years; median prostate-specific antigen [PSA], 6.2 ng/mL), all providing signed informed consent, underwent 7 T mpMRI with an external 8-channel body-array transmit coil and an endorectal receive coil between September 2013 and October 2014...
December 20, 2016: Investigative Radiology
https://www.readbyqxmd.com/read/27995303/integration-of-mri-to-clinical-nomogram-for-predicting-pathological-stage-before-radical-prostatectomy
#9
Cedric Lebacle, Françoise Roudot-Thoraval, Anissa Moktefi, Mohamed Bouanane, Alexandre De La Taille, Laurent Salomon
BACKGROUND: Debate persists regarding whether MRI should be used routinely for preoperative evaluation of prostate cancer. OBJECTIVE: The aim is to assess the role of prostatic magnetic resonance imaging (MRI) and other preoperative data in extra-prostatic extension (EPE) evaluation. PATIENTS AND METHODS: From 2000 to 2013, 1743 patients operated for radical prostatectomy had a preoperative MRI. Age, clinical stage with digital rectal exam (DRE), PSA, prostate weight, biopsy, MRI and pathological findings of the surgical specimen were noticed...
December 19, 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27987276/in-gantry-mri-guided-prostate-biopsy-diagnosis-of-prostatitis-and-its-relationship-with-pirads-v-2-based-score
#10
Rajeev Jyoti, Noel Hamesh Jina, Hodo Z Haxhimolla
INTRODUCTION: The recent literature has focussed predominantly on prostate cancer detection which has been revolutionized by multiparametric magnetic resonance imaging (mpMRI). Due to an overlap of features, prostatitis may mimic prostate cancer on MRI, especially in patients with chronic prostatitis. We retrospectively analysed our in-gantry MRI-guided biopsy (MRGB) results to determine incidental detection rate of prostatitis in Prostate Imaging Reporting and Data System (PIRADS) 3, 4 and 5 foci reported on diagnostic MRI of the prostate...
December 16, 2016: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/27986208/advances-in-prostate-cancer-magnetic-resonance-imaging-and-positron-emission-tomography-computed-tomography-for-staging-and-radiotherapy-treatment-planning
#11
REVIEW
Drew Moghanaki, Baris Turkbey, Neha Vapiwala, Behfar Ehdaie, Steven J Frank, Patrick W McLaughlin, Mukesh Harisinghani
Conventional prostate cancer staging strategies have limited accuracy to define the location, grade, and burden of disease. Evaluations have historically relied upon prostate-specific antigen levels, digital rectal examinations, random systematic biopsies, computed tomography, pelvic lymphadenectomy, or (99m)technetium methylene diphosphonate bone scans. Today, risk-stratification tools incorporate these data in a weighted format to guide management. However, the limitations and potential consequences of their uncertainties are well known...
January 2017: Seminars in Radiation Oncology
https://www.readbyqxmd.com/read/27975146/t2-weighted-mri-derived-textural-features-reflect-prostate-cancer-aggressiveness-preliminary-results
#12
Gabriel Nketiah, Mattijs Elschot, Eugene Kim, Jose R Teruel, Tom W Scheenen, Tone F Bathen, Kirsten M Selnæs
PURPOSE: To evaluate the diagnostic relevance of T2-weighted (T2W) MRI-derived textural features relative to quantitative physiological parameters derived from diffusion-weighted (DW) and dynamic contrast-enhanced (DCE) MRI in Gleason score (GS) 3+4 and 4+3 prostate cancers. MATERIALS AND METHODS: 3T multiparametric-MRI was performed on 23 prostate cancer patients prior to prostatectomy. Textural features [angular second moment (ASM), contrast, correlation, entropy], apparent diffusion coefficient (ADC), and DCE pharmacokinetic parameters (K(trans) and Ve) were calculated from index tumours delineated on the T2W, DW, and DCE images, respectively...
December 14, 2016: European Radiology
https://www.readbyqxmd.com/read/27964906/results-of-multiparametric-transrectal-ultrasound-based-focal-high-dose-rate-dose-escalation-combined-with-supplementary-external-beam-irradiation-in-intermediate-and-high-risk-localized-prostate-cancer-patients
#13
György Kovács, Klaudia Müller, Tamer Soror, Corinna Melchert, Xiyuan Guo, Dieter Jocham, Axel Merseburger
PURPOSE: Clinical results of a biologic information-based focused dose escalation combined with dose de-escalation for the whole organ in external beam radiotherapy + high-dose-rate brachytherapy (HDR-BT) boost application for localized prostate cancer in a consecutively treated patient cohort. METHODS AND MATERIALS: One hundred thirty patients were treated with external beam radiotherapy (50 Gy) complementary to two multiparametric transrectal ultrasound-guided 15 Gy HDR-BT fractions...
December 7, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27964905/acr-appropriateness-criteria-permanent-source-brachytherapy-for-prostate-cancer
#14
REVIEW
Brian J Davis, Al V Taira, Paul L Nguyen, Dean G Assimos, Anthony V D'Amico, Alexander R Gottschalk, Gary S Gustafson, Sameer R Keole, Stanley L Liauw, Shane Lloyd, Patrick W McLaughlin, Benjamin Movsas, Bradley R Prestidge, Timothy N Showalter, Neha Vapiwala
PURPOSE: To provide updated American College of Radiology (ACR) appropriateness criteria for transrectal ultrasound-guided transperineal interstitial permanent source brachytherapy. METHODS AND MATERIALS: The ACR appropriateness criteria are evidence-based guidelines for specific clinical conditions that are reviewed every 3 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel...
December 7, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27955940/magnetic-resonance-imaging-transrectal-ultrasound-fusion-focal-cryotherapy-of-the-prostate-a-prospective-development-study
#15
Massimo Valerio, Taimur Tariq Shah, Paras Shah, Neil Mccartan, Mark Emberton, Manit Arya, Hashim Uddin Ahmed
OBJECTIVES: The use of software-based magnetic resonance-transrectal ultrasound fusion to deliver focal therapy may increase the precision of treatment. This is a prospective development study assessing the feasibility of Magnetic resonance imaging-transrectal ultrasound (MRI-TRUS) fusion focal cryotherapy. METHODS AND MATERIALS: Consecutive patients undergoing focal cryotherapy were included in an academic registry (December 2013-June 2014). MRI-TRUS fusion focal cryotherapy was offered to men with visible clinically significant prostate cancer (Galil SeedNet system)...
December 7, 2016: Urologic Oncology
https://www.readbyqxmd.com/read/27943099/incremental-value-of-high-b-value-diffusion-weighted-magnetic-resonance-imaging-at-3-t-for-prediction-of-extracapsular-extension-in-patients-with-prostate-cancer-preliminary-experience
#16
Ayumu Kido, Tsutomu Tamada, Teruki Sone, Naoki Kanomata, Yoshiyuki Miyaji, Akira Yamamoto, Katsuyoshi Ito
PURPOSE: To investigate whether high b value diffusion-weighted imaging (DWI) contributes to the improvement of diagnostic ability of extracapsular extension (ECE) in prostate cancer (PC). MATERIALS AND METHODS: Forty-three patients with PC underwent multiparametric MRI including DWI (b values: 0, 2000 s/mm(2)) at 3-T. Two radiologists assessed the presence of ECE and the diagnostic certainty degree using conventional diagnostic method by consensus. Tumor apparent diffusion coefficient (ADC, ×10(-3) mm(2)/s) was also measured...
December 9, 2016: La Radiologia Medica
https://www.readbyqxmd.com/read/27939349/an-initial-negative-round-of-targeted-biopsies-in-men-with-highly-suspicious-multiparametric-magnetic-resonance-findings-does-not-exclude-clinically-significant-prostate-cancer-preliminary-experience
#17
Daniel N Costa, Fernando U Kay, Ivan Pedrosa, Lauren Kolski, Yair Lotan, Claus G Roehrborn, Brad Hornberger, Yin Xi, Franto Francis, Neil M Rofsky
BACKGROUND: Targeted prostate biopsies are changing the landscape of prostate cancer (PCa) diagnosis with the degree of suspicion on multiparametric magnetic resonance imaging (mpMRI) being a strong predictor of targeted biopsy outcome. Data regarding the rate and potential causes of false-negative magnetic resonance imaging-transrectal ultrasound (MRI-TRUS) fusion-targeted biopsy in patients with highly suspicious mpMRI findings are lacking. OBJECTIVES: To determine the rate of clinically significant PCa detection in repeat targeted biopsy or surgery in patients with highly suspicious mpMRI findings and in an initial negative MRI-TRUS fusion-targeted biopsy...
December 8, 2016: Urologic Oncology
https://www.readbyqxmd.com/read/27927229/evaluation-of-tumor-recurrences-after-radical-prostatectomy-using-18f-choline-pet-ct-and-3t-multiparametric-mri-without-endorectal-coil-a-single-center-experience
#18
Felipe Couñago, Manuel Recio, Antonio Maldonado, Elia Del Cerro, Ana Aurora Díaz-Gavela, Israel J Thuissard, David Sanz-Rosa, Francisco José Marcos, Karmele Olaciregui, María Mateo, Laura Cerezo
BACKGROUND: To evaluate and compare the utility of 18F-fluorocholine (18F-CH) PET/CT versus 3-Tesla multiparametric MRI (mpMRI) without endorectal coil to detect tumor recurrences in patients with biochemical relapse following radical prostatectomy (RP). Secondarily, to identify possible prognostic variables associated with mpMRI and 18F-CH PET/CT findings. METHODS: Retrospective study of 38 patients who developed biochemical recurrence after RP between the years 2011 and 2015 at our institution...
December 7, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27906722/location-and-grade-of-prostate-cancer-diagnosed-by-transperineal-template-guided-mapping-biopsy-after-negative-transrectal-ultrasound-guided-biopsy
#19
Nathan Bittner, Gregory Merrick, Al Taira, Abbey Bennett, Amy Schattel, Wayne Butler, Robert Galbreath, Edward Adamovich
OBJECTIVES: To determine the location and grade of prostate cancer diagnosed by transperineal template-guided mapping (TTMB) after negative transrectal ultrasound-guided (TRUS) biopsy. MATERIALS AND METHODS: This analysis consisted of 1118 consecutive patients who underwent TTMB from January 2005 to August 2015. Eight hundred thirty-five underwent TTMB after at least 1 negative TRUS biopsy and 283 underwent TTMB as the first biopsy procedure. The study population was divided into cohorts based on the number of prior TRUS biopsy sessions (0, 1, 2, and ≥3)...
November 30, 2016: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27882307/metabolic-imaging-in-prostate-cancer-where-we-are
#20
REVIEW
Claudia Testa, Cristian Pultrone, David Neil Manners, Riccardo Schiavina, Raffaele Lodi
In recent years, the development of diagnostic methods based on metabolic imaging has been aimed at improving diagnosis of prostate cancer (PCa) and perhaps at improving therapy. Molecular imaging methods can detect specific biological processes that are different when detected within cancer cells relative to those taking place in surrounding normal tissues. Many methods are sensitive to tissue metabolism; among them, positron emission tomography (PET) and magnetic resonance spectroscopic imaging (MRSI) are widely used in clinical practice and clinical research...
2016: Frontiers in Oncology
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