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Jonathan H Chen, Parastou Shilian, Justin Cheongsiatmoy, Andres A Gonzalez
PURPOSE: Intraoperative neurophysiologic monitoring involves the use of various modalities, including somatosensory evoked potentials (SEP), to assess the integrity of the at-risk nervous system during surgeries. Reliable baseline tracings are important because they are data against which future tracings are compared to detect potential injury. In some cases, adequate baselines may be difficult to achieve. Therefore, we analyzed several patient-specific factors to determine which variables are associated with inadequate intraoperative SEP baseline signals...
June 21, 2018: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
Chanu Rhee, Sarah R Brown, Travis M Jones, Cara O'Brien, Anupam Pande, Yasir Hamad, Amy L Bulger, Kathleen A Tobin, Anthony F Massaro, Deverick J Anderson, David K Warren, Michael Klompas
We compared sepsis "time zero" and Centers for Medicare and Medicaid Services (CMS) SEP-1 pass rates among 3 abstractors in 3 hospitals. Abstractors agreed on time zero in 29 of 80 (36%) cases. Perceived pass rates ranged from 9 of 80 cases (11%) to 19 of 80 cases (23%). Variability in time zero and perceived pass rates limits the utility of SEP-1 for measuring quality.
June 22, 2018: Infection Control and Hospital Epidemiology
Tsvetelina Yungareva, Zoltan Urshev
In lactobacilli the aggregation phenotype is linked to their ability to colonize the intestinal and urogenital tracts and to counteract pathogenic bacteria. In all available complete genome sequences of Lactobacillus delbrueckii ssp. bulgaricus there are at least two genes putatively related to aggregation, one of which is annotated as aggregation-promoting factor (apf). Here we report the results from the in silico analysis of this gene and its product. The apf gene was present in the genome of all 70 tested L...
June 19, 2018: World Journal of Microbiology & Biotechnology
Asima Rani, Syed Kashif Nawaz, Muhammad Arshad, Shazia Irfan
Background: Toll-like receptors (TLRs) of the human immune mechanism play important role in the detection of invading pathogens. TLRs specifically recognize the pathogen-associated molecular patterns (PAMPs) from pathogens and start the effective response. Single nucleotide polymorphisms (SNPs) in the TLRs can mediate their functions. Present study evaluated the importance of rs4986790 polymorphism of TLR4 gene in susceptibility towards malaria, clinical outcomes of the disease and responsible species of malaria...
May 2018: Iranian Journal of Public Health
Lukas Heydrich, Jane Elizabeth Aspell, Guillaume Marillier, Tom Lavanchy, Bruno Herbelin, Olaf Blanke
Prominent theories highlight the importance of bodily perception for self-consciousness, but it is currently not known whether this is based on interoceptive or exteroceptive signals or on integrated signals from these anatomically distinct systems, nor where in the brain such integration might occur. To investigate this, we measured brain activity during the recently described 'cardio-visual full body illusion' which combines interoceptive and exteroceptive signals, by providing participants with visual exteroceptive information about their heartbeat in the form of a periodically illuminated silhouette outlining a video image of the participant's body and flashing in synchrony with their heartbeat...
June 18, 2018: Scientific Reports
Dong-Mei Wei, Shiu Lun Au Yeung, Jian-Rong He, Wan-Qing Xiao, Jin-Hua Lu, Si Tu, Nian-Nian Chen, Kin Bong Hubert Lam, Kar-Keung Cheng, Gabriel M Leung, Hui-Min Xia, C Mary Schooling, Xiu Qiu
BACKGROUND: Few studies have examined the association between a composite measure of family socio-economic position (SEP)2 and depressive symptoms among Chinese pregnant women, nor any potential underlying mechanisms which may be amenable to preventative interventions. METHODS: We investigated the association between a composite SEP measure and depressive symptoms during early pregnancy, and tested for mediation by social support and moderation by parity in the Born in Guangzhou Cohort Study (n = 12,382) using adjusted logistic regression and causal mediation analysis...
June 5, 2018: Journal of Affective Disorders
C Genna, C Oddo, C Fanciullacci, C Chisari, S Micera, F Artoni
Roughness is the most important feature for texture discrimination. Here we investigate how the bilateral cortical representation of touch is modulated by tactile roughness by analyzing the neural responses elicited by stimuli with various coarseness levels ranging from fine to medium. A prolonged stimulation was delivered to 10 healthy subjects by passively sliding a tactile stimuli under the fingertip while recording the EEG to study the modulation of Somatosensory Evoked Potentials (SEPs) as well as activity in the theta and alpha bands...
June 13, 2018: Brain Research
Maenia Scarpino, Giovanni Lanzo, Francesco Lolli, Riccardo Carrai, Marco Moretti, Maddalena Spalletti, Morena Cozzolino, Adriano Peris, Aldo Amantini, Antonello Grippo
The data presented in this article are related to our research article entitled 'Neurophysiological and neuroradiological multimodal approach for early poor outcome prediction after cardiac arrest' (Scarpino et al., 2018) [1]. We reported two additional analyses, including results gathered from somatosensory evoked potentials(SEPs), brain computed tomography(CT) and electroencephalography(EEG) performed on 183 subjects within the first 24 h after cardiac arrest(CA). In the first analysis, we considered the Cerebral Performance Categories(CPC) 3, 4 and 5a,b (severe disability, unresponsive wakefulness state, neurological death and non-neurological death, respectively) as poor outcomes...
August 2018: Data in Brief
Jinbao Liu, Jichang Han, Yang Zhang, Huanyuan Wang, Hui Kong, Lei Shi
The storage of soil organic carbon (SOC) should improve soil fertility. Conventional determination of SOC is expensive and tedious. Visible-near infrared reflectance spectroscopy is a practical and cost-effective approach that has been successfully used SOC concentration. Soil spectral inversion model could quickly and efficiently determine SOC content. This paper presents a study dealing with SOC estimation through the combination of soil spectroscopy and stepwise multiple linear regression (SMLR), partial least squares regression (PLSR), principal component regression (PCR)...
June 5, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Mohammad Zounemat-Kermani, Abdollah Ramezani-Charmahineh, Jan Adamowski, Ozgur Kisi
Chlorination, the basic treatment utilized for drinking water sources, is widely used for water disinfection and pathogen elimination in water distribution networks. Thereafter, the proper prediction of chlorine consumption is of great importance in water distribution network performance. In this respect, data mining techniques-which have the ability to discover the relationship between dependent variable(s) and independent variables-can be considered as alternative approaches in comparison to conventional methods (e...
June 13, 2018: Environmental Monitoring and Assessment
Young Saing Kim, Dong Kyun Park, In Cheol Hwang, Hong Yup Ahn
Background: The effect of weather conditions on human health has been documented. However, the role of daily weather on anticipated death remains unclear. This study aimed to evaluate the relationship between daily weather conditions and death in terminally ill cancer patients. Methods: We retrospectively searched a medical database of 935 consecutive terminally ill cancer patients who passed away in the palliative care unit from Oct 2009 to Sep 2013. We used Poisson regression to assess the relative risk (RR) of anticipated death based on various weather variables, using mean values calculated from the 10 d around the time of death...
April 2018: Iranian Journal of Public Health
Shumpei Fujii, Hiromitsu Tanaka, Tomoo Hirano
The decrease in number of AMPA-type glutamate receptor (AMPAR) at excitatory synapses causes LTD, a cellular basis of learning and memory. The number of postsynaptic AMPARs is regulated by the balance of exocytosis and endocytosis, and enhanced endocytosis of AMPAR has been suggested to underlie the LTD expression. However, it remains unclear how endocytosis and exocytosis of AMPAR change during LTD. In this study, we addressed this question by analyzing exocytosis and endocytosis of AMPAR by imaging super-ecliptic pHlorin (SEP)-tagged AMPAR around postsynaptic structure formed directly on the glass surface in the hippocampal culture prepared from rat embryos of both sexes...
June 13, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Vusal Aliyev, Shintaro Yagi, Ahmed Hammad, Amr Badawy, Yudai Sasaki, Yuki Masano, Gen Yamamoto, Naoko Kamo, Kojiro Taura, Hideaki Okajima, Toshimi Kaido, Shinji Uemoto
Sclerosing encapsulating peritonitis (SEP), or abdominal cocoon is a rare cause of intestinal obstruction, and still etiology remains unknown. We report a series of 4 patients with abdominal cocoon, and all the 4 patients had previously undergone living-donor liver transplantation (LDLT). There was no evidence of SEP before and during LDLT. At the time of diagnosis of SEP, 3 out of 4 patients had ascites. First and fourth patients had multiple episodes or attacks of cholangitis, which were managed by percutaneous transhepatic biliary drainage and hepaticojejunostomy, respectively...
May 2018: Annals of Hepato-Biliary-Pancreatic Surgery
Renata Kuras, Edyta Reszka, Edyta Wieczorek, Ewa Jablonska, Jolanta Gromadzinska, Beata Malachowska, Lucyna Kozlowska, Magdalena Stanislawska, Beata Janasik, Wojciech Wasowicz
The present observation based research was designed to evaluate the influence of occupational human exposure to metallic mercury (Hg°) vapor on the biomarkers of selenium status involved in the antioxidant defense system. For this purpose we determined Hg and selenium (Se) concentrations in body fluids, the markers of antioxidant effect measured as an activity of Se-dependent enzymes (red blood cell and plasma glutathione peroxidase: GPx1-RBC and GPx3-P), concentration of selenoprotein P in the plasma (SeP-P) and total antioxidant activity in the plasma (TAA-P) in 131 male workers from a chloralkali plant exposed to Hg° and 67 non-exposed males (control group)...
September 2018: Journal of Trace Elements in Medicine and Biology
Madeline C Frost, Emily C Williams, Susan Kingston, Caleb J Banta-Green
OBJECTIVES: Opioid use is a growing problem in the United States. Despite existence of effective treatments (eg, opioid agonist medication), most people with opioid use disorder do not receive treatment. Increasing treatment receipt is an essential component of the response to the opioid crisis. We examined factors associated with interest in getting help to reduce or stop substance use among syringe exchange program (SEP) clients who reported using opioids. METHODS: Surveys were administered at 17 SEPs across Washington State during 2015; 436 respondents who reported recent opioid use and not receiving current treatment were eligible for this analysis...
June 7, 2018: Journal of Addiction Medicine
Mengnan Wang, Fang Wu, Yujiao Yang, Huijuan Miao, Zhaoyang Fan, Xunming Ji, Debiao Li, Xiuhai Guo, Qi Yang
BACKGROUND: It has been shown that intracranial atherosclerotic stenosis (ICAS) has heterogeneous features in terms of plaque instability and vascular remodeling. Therefore, quantitative information on the changes of intracranial atherosclerosis and lenticulostriate arteries (LSAs) may potentially improve understanding of the pathophysiological mechanisms underlying stroke and may guide the treatment and work-up strategies. Our present study aimed to use a novel whole-brain high-resolution cardiovascular magnetic resonance imaging (WB-HRCMR) to assess both ICAS plaques and LSAs in recent stroke patients...
June 7, 2018: Journal of Cardiovascular Magnetic Resonance
Junichiro Funahashi, Hiromitsu Tanaka, Tomoo Hirano
Fast repetitive synaptic transmission depends on efficient exocytosis and retrieval of synaptic vesicles around a presynaptic active zone. However, the functional organization of an active zone and regulatory mechanisms of exocytosis, endocytosis and reconstruction of release-competent synaptic vesicles have not been fully elucidated. By developing a novel visualization method, we attempted to identify the location of exocytosis of a single synaptic vesicle within an active zone and examined movement of synaptic vesicle protein synaptophysin (Syp) after exocytosis...
2018: Frontiers in Cellular Neuroscience
Dipesh Das, Indu V Sabaraya, Tara Sabo-Attwood, Navid B Saleh
Carbon nanotubes are hybridized with metal crystals to impart multifunctionality into the nanohybrids (NHs). Simple but effective synthesis techniques are desired to form both zero-valent and oxides of different metal species on carbon nanotube surfaces. Sol-gel technique brings in significant advantages and is a viable technique for such synthesis. This study probes the efficacy of sol-gel process and aims to identify underlying mechanisms of crystal formation. Standard electron potential (SEP) is used as a guiding parameter to choose the metal species; i...
June 5, 2018: Nanomaterials
X L Zhang, M J Zhang, D L Liu, Q F Zhang
Objective: To analyze the etiological characteristics of patients in department of ENT with chief complaint of vertigo or dizziness in order to reduce the rate of misdiagnosis and wrong treatment. Method: A total of 3 137 patients in department of ENT with chief complaint of vertigo or dizziness from Sep 2015 to Sep 2017 were included and the etiologies were clarified retrospectively. And in which with any of the 8 kinds of disease including benign paroxysmal positional vertigo(BPPV), vestibular neuritis, vestibular migraine (VM), Meiniére disease, recurrent vestibular disease, sudden deafness with vertigo, psychogenic vertigo, posterior circulation ischemia (PCI) together 2 138 patients were further stratified analyzed by gender and age...
May 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Rocco Adiutori, Johan Aarum, Irene Zubiri, Michael Bremang, Stephan Jung, Denise Sheer, Ian Pike, Andrea Malaspina
Protein aggregation in biofluids is a poorly understood phenomenon. Under normal physiological conditions, fluid-borne aggregates may contain plasma or cell proteins prone to aggregation. Recent observations suggest that neurofilaments (Nf), the building blocks of neurons and a biomarker of neurodegeneration, are included in high molecular weight complexes in circulation. The composition of these Nf-containing hetero-aggregates (NCH) may change in systemic or organ-specific pathologies, providing the basis to develop novel disease biomarkers...
July 2018: Biochemistry and Biophysics Reports
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