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https://www.readbyqxmd.com/read/28231699/optimization-of-ultrasonic-assisted-enzymatic-hydrolysis-conditions-for-the-production-of-antioxidant-hydrolysates-from-porcine-liver-by-using-response-surface-methodology
#1
Hui-Chuan Yu, Fa-Jui Tan
Objective: The objective of this study was to optimize ultrasonic-assisted enzymatic hydrolysis conditions, including enzyme-to-substrate (E/S) ratio, pH, and temperature, for producing porcine liver hydrolysates (PLHs) with the highest 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity by using response surface methodology (RSM). Methods: The study used RSM to determine the combination of hydrolysis parameters that maximized the antioxidant activity of our PLHs...
February 23, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28231695/blood-amino-acids-profile-responding-to-heat-stress-in-dairy-cows
#2
Jiang Guo, Shengtao Gao, Suyu Quan, Yangdong Zhang, Dengpan Bu, Jiaqi Wang
The objective of this experiment was to investigate the effects of heat stress on milk protein and blood amino acid profile in dairy cows. Twelve dairy cows with the similar parity, days in milk and milk yield were randomly divided into two groups with six cows raised in summer and others in autumn, respectively. Constant managerial conditions and diets were maintained during the experiment. Measurements and samples for heat stress and no heat stress were obtained according to the physical alterations of the temperature-humidity index...
February 23, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28231693/native-plants-p-amurense-and-h-japonicus-extracts-act-as-antioxidants-to-support-developmental-competence-of-bovine-blastocysts
#3
Geon-Yeop Do, Jin-Woo Kim, Hyo-Jin Park, Seung-Bin Yoon, Jae-Young Park, Seul-Gi Yang, Bae Dong Jung, Yong-Soo Kwon, Man-Jong Kang, Bong-Seok Song, Sun-Uk Kim, Kyu-Tae Chang, Deog-Bon Koo
Objective: Phellodendron amurense (P. amurense) and Humulus japonicus (H. japonicus) are closely involved in anti-oxidative response and increasing antioxidant enzymes activities. However, the effects of their extracts on development of preimplantation bovine embryos have not yet been investigated. Therefore, we investigated the effects of P. amurense and H. japonicus extract on developmental competence and quality of preimplantation bovine embryos. Methods: After in vitro fertilization, bovine embryos were cultured for 7 days in CR1aa medium supplemented with P...
February 23, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28231689/are-children-with-asthma-in-south-korea-also-associated-with-vitamin-d-deficiency
#4
Yu-Ri Kim, Sung-Chul Seo, Young Yoo, Ji Tae Choung
Recently, epidemiologic studies have shown that the lack of vitamin D levels may be associated with high asthma prevalence, but its effect is still controversial, depending on season, area, and food consumption. We aimed to examine the association of serum vitamin D levels with the prevalence of pediatric asthma in Korea. A total of 80 children (50 asthmatic children and 30 healthy controls) aged 6-14 years were participated in this study. Serum 25-hydroxy vitamin D (vitamin D) levels were measured and compared between the two groups...
February 14, 2017: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/28231683/the-adverse-effects-of-exercise-and-supraphysiological-dose-of-testosterone-enanthate-te-on-exploratory-activity-in-elevated-plus-maze-epm-test-indications-for-using-total-exploratory-activity-tea-as-a-new-parameter-for-exploratory-activity-estimation-in-epm
#5
(no author information available yet)
OBJECTIVES: The aim of this study was the estimation of effects induced by chronic administration of supraphysiological dose of TE and prolonged exercise in male rats on anxiety levels (alterations in exploratory activity patterns in EPM). MATERIAL AND METHODS: Two sedentary (control - C and testosterone-enanthate - T) and two exercise (exercise - E and testosterone-enanthate plus exercise - T+E) groups (n=32) underwent adequate protocols - the swimming protocol (1 h/day) and TE (20 mg/kg/w, s...
October 24, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28231680/-a-review-on-the-advancement-of-internet-based-public-health-surveillance-program
#6
Y Q Zhao, W J Ma
Internet data is introduced into public health arena under the features of fast updating and tremendous volume. Mining and analyzing internet data, researchers can model the internet-based surveillance system to assess the distribution of health-related events. There are two main types of internet-based surveillance systems, i.e. active and passive, which are distinguished by the sources of information. Through passive surveillance system, information is collected from search engine and social media while the active system gathers information through provision of the volunteers...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231661/-a-retrospective-cohort-study-on-survival-status-of-aids-patients-among-15-or-above-year-olds-in-henan-province-from-2008-to-2015
#7
W J Yang, N Li, Y Liang, J Li, P Y Fan, D Y Sun, Q Zhu, Z Wang
Objective: To explore the survival status and affecting factors among patients diagnosed as AIDS, in Henan province. Methods: Database of AIDS patients were downloaded from the China information system for disease prevention and control-AIDS with a retrospective study conducted. Inclusion criteria on patients would involve those diagnosed between 2008 and 2015, aged 15 years or above. Results: A total number of 25 525 HIV/AIDS patients were enrolled in this study. During the follow-up period, the overall mortality among all the patients was 24...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231654/-relation-between-waist-circumference-and-risk-of-male-lung-cancer-incidence-a-prospective-cohort-study
#8
S H Xie, G Wang, L W Guo, S H Chen, K Su, F Li, S Chang, X S Feng, Z Y Lyu, Y H Chen, J S Ren, H Cui, N Li, S L Wu, M Dai, J He
Objective: To investigate the association between waist circumference and risk of male lung cancer incidence. Methods: Since May 1, 2006, all the male employees including the retirees in Kailuan Group had been recruited into a Chinese Kailuan Male Cohort study. Information on anthropometries including body weight, height and waist circumference were collected at the baseline investigation, as well as information on newly-diagnosed lung cancer cases during the follow-up period. Waist circumference was grouped by quintiles of the population waist circumference distribution and categorized into the following five groups: <80, 80-, 85-, 90- and ≥95 cm, with the relevant normal group, the second quintile group (80-cm), serving as the referent category...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231653/implantless-fixation-of-a-large-osteocartilaginous-fracture-of-the-lateral-femoral-condyle-in-a-child
#9
Jitendra Maheshwari, Vikram Mhaskar, Parul Maheshwari Mhaskar
We describe for the first time a case of lateral femoral condyle fracture following a fall in a 13-year-old child that was reduced arthroscopically using a probe. It was definitively fixed with 0 vicryl sutures in a cruciate pattern after being initially stabilised with 1.5-mm Kirschner wires. Four beath pins carrying sutures were drilled at four opposing quadrants through the reduced fragment into the femur. The sutures were then tied on the lateral cortex of the femur. After fixation, the child was kept non-weight bearing for 6 weeks, partial weight bearing from 6 weeks to 12 weeks and then full weight bearing thereafter...
March 1, 2017: Knee Surgery & related Research
https://www.readbyqxmd.com/read/28231640/mind-the-gap-mechanisms-regulating-the-endothelial-barrier
#10
REVIEW
Mariya Y Radeva, Jens Waschke
The endothelial barrier consists of intercellular contacts localized in the cleft between endothelial cells, which is covered by the glycocalyx in a sieve-like manner. Both types of barrier-forming junctions, i.e. the adherens junction (AJ) serving mechanical anchorage and mechanotransduction and the tight junction (TJ) sealing the intercellular space to limit paracelullar permeability, are tethered to the actin cytoskeleton. Under resting conditions, the endothelium thereby builds a selective layer controlling the exchange of fluid and solutes with the surrounding tissue...
February 23, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28231629/the-evaluation-of-physical-activity-for-community-dwelling-patients-with-hypertension
#11
Chunhua Ma
AIMS AND OBJECTIVES: The study aimed to evaluate the proportion of Chinese patients with hypertension who meet the Chinese Hypertension Management Guideline recommendations for weekly physical activity and to determine possible associated factors that impact meeting the weekly physical activity recommendation. BACKGROUND: Accurate evaluation of physical activity levels for hypertensive patients is important to determine patients' health outcomes and intervention measures...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231626/default-mode-network-deactivation-to-smoking-cue-relative-to-food-cue-predicts-treatment-outcome-in-nicotine-use-disorder
#12
Claire E Wilcox, Eric D Claus, Vince D Calhoun, Srinivas Rachakonda, Rae A Littlewood, Jessica Mickey, Pamela B Arenella, Natalie Goodreau, Kent E Hutchison
Identifying predictors of treatment outcome for nicotine use disorders (NUDs) may help improve efficacy of established treatments, like varenicline. Brain reactivity to drug stimuli predicts relapse risk in nicotine and other substance use disorders in some studies. Activity in the default mode network (DMN) is affected by drug cues and other palatable cues, but its clinical significance is unclear. In this study, 143 individuals with NUD (male n = 91, ages 18-55 years) received a functional magnetic resonance imaging scan during a visual cue task during which they were presented with a series of smoking-related or food-related video clips prior to randomization to treatment with varenicline (n = 80) or placebo...
February 23, 2017: Addiction Biology
https://www.readbyqxmd.com/read/28231625/experimental-study-on-1-25-oh-2-d3-amelioration-of-oral-lichen-planus-through-regulating-nf-%C3%AE%C2%BAb-signaling-pathway
#13
Jie Du, Ran Li, Feiyan Yu, Fang Yang, Jinhua Wang, Qingyong Chen, Xiangyu Wang, Bin Zhao, Fang Zhang
OBJECTIVE: To explore the protective function of vitamin D (VD)/vitamin D receptor (VDR) on the development of oral lichen planus (OLP) and elaborate the underling mechanism of it. METHODS: H&E staining, myeloid Peroxidase (MPO) assays, quantitative PCR (qPCR), western blotting and Elisa were used to test the human biopsies and serum. QPCR, western blotting, Elisa and siRNA transfection were also performed in LPS-induced keratinocytes to observe the functions of vitamin D and VDR...
February 23, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28231624/targets-and-mechanisms-in-prevention-of-parkinson-s-disease-through-immunomodulatory-treatments
#14
REVIEW
Marianne von Euler Chelpin, Thomas Vorup-Jensen
Parkinson's Disease (PD) is the second most common neurodegenerative disease in the world, however, there is no cure for it. Current treatments only relieve some of the symptoms, without ceasing the disease, and lose efficacy with prolonged treatment. Considerable evidence shows that persistent inflammatory responses, involving T cell infiltration and glial cell activation, are common characteristics of human patients and play a crucial role in the degeneration of dopaminergic neurons. Therefore, it is important to develop therapeutic strategies that can impede or halt the disease through the modulation of the peripheral immune system by aiming at controlling the existing neuroinflammation...
February 23, 2017: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/28231620/sustaining-guideline-implementation-a-multi-site-perspective-on-activities-challenges-and-supports
#15
Kathryn Smith Higuchi, Barbara Davies, Jenny Ploeg
AIMS AND OBJECTIVES: To examine activities conducted, challenges encountered, and supports used when sustaining nursing practice guideline implementation in multiple health care organizations over three years. BACKGROUND: Numerous models and frameworks exist to guide the implementation of guidelines, yet very few focus on sustaining improved practice changes. It is not known if one intervention or multiple interventions are required, nor the long-term activities, challenges, and supports for sustaining improved practices...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231617/characterization-of-staphylococcus-epidermidis-strains-isolated-from-industrial-cleanrooms-under-regular-routine-disinfection
#16
U Ribič, A Klančnik, B Jeršek
AIMS: The purpose of this study was the genotypic and phenotypic characterization of 57 strains of Staphylococcus epidermidis isolated from cleanroom environments, based on their biofilm formation and antimicrobial resistance profiles. METHODS AND RESULTS: Biofilm formation was investigated using real-time PCR (icaA, aap, bhp genes), the Congo red agar method, and the crystal violet assay. The majority of the strains (59.7%; 34/57) did not form biofilms according to the crystal violet assay, although the biofilm-associated genes were present in 94...
February 23, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28231615/what-do-older-people-experiencing-loneliness-think-about-primary-care-or-community-based-interventions-to-reduce-loneliness-a-qualitative-study-in-england
#17
Kalpa Kharicha, Steve Iliffe, Jill Manthorpe, Carolyn A Chew-Graham, Mima Cattan, Claire Goodman, Maggie Kirby-Barr, Janet H Whitehouse, Kate Walters
Loneliness in later life is a common problem with poor health outcomes. However, interventions to prevent or ameliorate loneliness have a weak evidence base. The views of older people experiencing or at risk of loneliness in the community are important in identifying features of potential support, but have been little studied. Twenty-eight community dwelling people, aged 65 and over who reported being 'lonely much of the time' or identified as lonely from the de Jong Gierveld six-item loneliness scale in a larger study, participated in in-depth interviews, between June 2013 and May 2014...
February 23, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28231612/the-pro-inflammatory-cytokine-tnf-%C3%AE-inhibits-lymphatic-pumping-via-activation-of-the-nf-%C3%AE%C2%BAb-inos-signaling-pathway
#18
Yingxuan Chen, Sonia Rehal, Simon Roizes, Hai-Lei Zhu, William C Cole, Pierre-Yves von der Weid
OBJECTIVE: Mesenteric lymphatic vessels pumping, important to propel lymph and immune cells from the intestinal interstitium to the mesenteric lymph nodes, is compromised during intestinal inflammation. The objective of this study was to test the hypothesis that the pro-inflammatory cytokine tumor necrosis factor alpha (TNF-α), is a significant contributor to the inflammation-induced lymphatic contractile dysfunction, and to determine its mode of action. METHODS: Contractile parameters were obtained form isolated rat mesenteric lymphatic vessels mounted on a pressure myograph after 24-h incubation with or without TNF-α...
February 23, 2017: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/28231606/user-participation-is-a-family-matter-a-multiple-case-study-of-the-experiences-of-older-hospitalized-people-and-their-relatives
#19
Ingrid Nyborg, Lars Johan Danbolt, Marit Kirkevold
AIMS AND OBJECTIVES: The purpose of this multiple case study was to compare and contrast older people's and their relatives' experiences of participation in decision-making processes regarding the planning of everyday life after discharge from hospital. BACKGROUND: Internationally, patient involvement in health services is established to benefit patient health and to improve quality of the services. The literature shows that at hospital discharge older people would benefit from better communication and more active participation of relatives in the discharge planning...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231569/biomarkers-in-autoimmune-salivary-gland-disorders-a-review
#20
Benedikt Hofauer, Klaus Thuermel, Constanze Gahleitner, Andreas Knopf
Salivary glands are frequent sites of manifestations of autoimmune disorders in the head and neck. Sjögren syndrome, sarcoidosis, granulomatosis with polyangiitis, and IgG4-related sialadenitis represent the most important autoimmune salivary gland disorders. Due to the lack of specific symptoms, diagnosis of these conditions remains a challenge. Diagnosis is usually based on classification criteria involving clinical tests, histopathological evaluation, and serological examinations. Depending on the disease, biomarkers are of different value and have to be interpreted carefully...
February 24, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
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