Valentina Cattaneo, Alessio Caccioppola, Sebastiano Maria Colombo, Vittorio Scaravilli, Daniela Tubiolo, Stefania Crotti, Marco Bosone, Paola Rafaniello Raviele, Edoardo Olmeda, Francesca Menni, Francesca Furlan, Valeria Rossetti, Francesco Damarco, Mauro Panigada, Giacomo Grasselli
Hyperammonemia after lung transplantation is a rare but potentially fatal condition. A 59-year-old male patient affected by pulmonary fibrosis underwent an uncomplicated bilateral lung transplant. Fourteen days after the procedure, the patient developed severe encephalopathy caused by elevated serum ammonia levels. Ureaplasma parvum and Mycoplasma hominis were found on bronchial aspirate and urinary samples as well as on pharyngeal and rectal swabs. Despite the initiation of multimodal therapy, brain damage due to hyperosmolarity was so extensive to evolve into brain death...
August 2, 2023: Transplantation Proceedings