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selenium nanoparticle

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https://www.readbyqxmd.com/read/28923779/selenium-nanoparticles-enhanced-thermal-tolerance-and-maintain-cellular-stress-protection-of-pangasius-hypophthalmus-reared-under-lead-and-high-temperature
#1
Neeraj Kumar, K K Krishnani, Sanjay Kumar Gupta, Narendra Pratap Singh
There is strong relation between nutrition and thermal tolerance of fish in terms of improved critical temperature minima (CTmin), lethal temperature minima (LTmin), critical temperature maxima (CTmax), and lethal temperature maxima (LTmax). Fishes act as quantifying indicators to the climate change due to their critical thermal limits in nature and ability to adjust thermal sensitivity to maintain their homeostasis. In the present study, biologically synthesised selenium nanoparticles (Se-NPs) from fisheries waste (fish gill) was used to evaluate its efficacy for enhancement of thermal tolerance of Pangasius hypophthalmus reared under lead (Pb) and high temperature (34°C) for 72 days...
September 15, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28892773/assessment-of-toxicity-of-selenium-and-cadmium-selenium-quantum-dots-a-review
#2
REVIEW
Virender K Sharma, Thomas J McDonald, Mary Sohn, George A K Anquandah, Maurizio Pettine, Radek Zboril
This paper reviews the current understanding of the toxicity of selenium (Se) to terrestrial mammalian and aquatic organisms. Adverse biological effects occur in the case of Se deficiencies, associated with this element having essential biological functions and a narrow window between essentiality and toxicity. Several inorganic species of Se (-2, 0, +4, and +6) and organic species (monomethylated and dimethylated) have been reported in aquatic systems. The toxicity of Se in any given sample depends not only on its speciation and concentration, but also on the concomitant presence of other compounds that may have synergistic or antagonistic effects, affecting the target organism as well, usually spanning 2 or 3 orders of magnitude for inorganic Se species...
August 26, 2017: Chemosphere
https://www.readbyqxmd.com/read/28892302/cancer-targeted-selenium-nanoparticles-sensitize-cancer-cells-to-continuous-%C3%AE-radiation-to-achieve-synergetic-chemo-radiotherapy
#3
Leung Chan, Lizhen He, Binwei Zhou, Shouhai Guan, Mingjun Bo, Yahui Yang, Ying Liu, Xiao Liu, Yanyang Zhang, Qiang Xie, Tianfeng Chen
Cancer radiotherapy with 125I seeds demonstrates long-term higher efficacy and lower side effects than traditional X-ray radiotherapy due to its low-dose and continuous radiation but is still limited by radioresistance in clinical applications. Therefore, the design and synthesis for sensitizers that could enhance the sensitivity of cancer cells to 125I seeds is of great importance for future radiotherapy. Selenium nanoparticles (SeNPs) have been found to exhibit high potential in cancer chemotherapy and as drug carriers...
September 11, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28890369/selenium-incorporated-guar-gum-nanoparticles-safeguards-mitochondrial-bioenergetics-during-ischemia-reperfusion-injury-in-h9c2-cardiac-cells
#4
R S Soumya, Prathapan Ayyappan, P Salin Raj, V P Vineetha, K G Raghu
The application of nanotechnology has created high impact in diagnosis and prognosis of various disorders including cardiovascular diseases. In the present study, we investigated the beneficial effect of selenium incorporated guar gum nanoparticles (SGG) compared to nascent selenium (Se) and guar gum nanoparticle (GGN) against ischemia-reperfusion induced alterations in oxidative phosphorylation and energy metabolism in H9c2 cardiac cells. Ischemia and reperfusion were induced for 1h. The alterations in activities of various complexes (complex 1, II, III and IV) of mitochondrial electron transport chain (ETC), aconitase activity, oxygen consumption rate, and the ATP content were seen...
September 7, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28880681/synthesis-and-antioxidant-properties-of-lycium-barbarum-polysaccharides-capped-selenium-nanoparticles-using-tea-extract
#5
Wenjing Zhang, Juan Zhang, Dejun Ding, Liping Zhang, Luis Alexandre Muehlmann, Shu-E Deng, Xuedong Wang, Wentong Li, Weifen Zhang
Selenium nanoparticles (SeNPs) have attracted increasing interest over the last decades because of their activities on redox balance in human body. However, the SeNPs tend to aggregate into large clusters, resulting in lower bioactivity, bioavailability and biocompatibility. Surface-capping agents on SeNPs play crucial roles in its stabilization and biological activity. Here, a green synthesis method for the preparation of Lycium barbarum polysaccharides capped SeNPs using green tea extracts as reductants under mild conditions, at room temperature, is reported...
September 7, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28859809/selenium-nanoparticle-enriched-biomass-of-yarrowia-lipolytica-enhances-growth-and-survival-of-artemia-salina
#6
Faseela Hamza, Amogh Vaidya, Mugdha Apte, Ameeta Ravi Kumar, Smita Zinjarde
Controlling disease outbreaks is a major challenge in aquaculture farms and conventional methods are often ineffective. Nutritional supplementation and probiotic preparations help in reducing severity of such infections. The generally regarded as safe yeast (Yarrowia lipolytica) was used in the current study. A marine strain of Y. lipolytica exhibited tolerance towards sodium selenite and formed cell associated selenium nanoparticles (SeNPs). The synthesized nanoparticles were characterized by UV-vis spectroscopy, X-ray diffraction (XRD) and Field Emission Scanning Electron Microscope (FE-SEM) observations...
November 2017: Enzyme and Microbial Technology
https://www.readbyqxmd.com/read/28825808/directed-biofabrication-of-nanoparticles-through-regulating-extracellular-electron-transfer
#7
Li-Jiao Tian, Wen-Wei Li, Ting-Ting Zhu, Jie-Jie Chen, Wei-Kang Wang, Peng-Fei An, Long Zhang, Jun-Cai Dong, Yong Guan, Dong-Feng Liu, Nan-Qing Zhou, Gang Liu, Yang-Chao Tian, Han-Qing Yu
Biofabrication of nanomaterials is currently constrained by a low production efficiency and poor controllability on product quality compared to chemical synthetic routes. In this work, we show an attractive new biosynthesis system to break these limitations. A directed production of selenium-containing nanoparticles in Shewanella oneidensis MR-1 cells, with fine-tuned composition and subcellular synthetic location, was achieved by modifying the extracellular electron transfer chain. By taking advantage of its untapped intracellular detoxification and synthetic power, we obtained high-purity, uniform-sized cadmium selenide nanoparticles in the cytoplasm, with the production rates and fluorescent intensities far exceeding the state-of-the-art biosystems...
August 24, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28819934/erratum-to-selenium-nanoparticles-with-low-level-ionizing-radiation-exposure-ameliorate-nicotine-induced-inflammatory-impairment-in-rat-kidney
#8
Walid E Zahran, Sawsan M Elsonbaty, Fatma S M Moawed
No abstract text is available yet for this article.
August 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28783048/exploring-the-behavior-and-metabolic-transformations-of-senps-in-exposed-lactic-acid-bacteria-effect-of-nanoparticles-coating-agent
#9
Maria Palomo-Siguero, Yolanda Madrid
The behavior and transformation of selenium nanoparticles (SeNPs) in living systems such as microorganisms is largely unknown. To address this knowledge gap, we examined the effect of three types of SeNP suspensions toward Lactobacillus delbrueckii subsp. bulgaricus LB-12 using a variety of techniques. SeNPs were synthesized using three types of coating agents (chitosan (CS-SeNPs), hydroxyethyl cellulose (HEC-SeNPs) and a non-ionic surfactant, surfynol (ethoxylated-SeNPs)). Morphologies of SeNPs were all spherical...
August 5, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28773975/synthesis-of-cdse-quantum-dots-using-fusarium-oxysporum
#10
Takaaki Yamaguchi, Yoshijiro Tsuruda, Tomohiro Furukawa, Lumi Negishi, Yuki Imura, Shohei Sakuda, Etsuro Yoshimura, Michio Suzuki
CdSe quantum dots are often used in industry as fluorescent materials. In this study, CdSe quantum dots were synthesized using Fusarium oxysporum. The cadmium and selenium concentration, pH, and temperature for the culture of F. oxysporum (Fusarium oxysporum) were optimized for the synthesis, and the CdSe quantum dots obtained from the mycelial cells of F. oxysporum were observed by transmission electron microscopy. Ultra-thin sections of F. oxysporum showed that the CdSe quantum dots were precipitated in the intracellular space, indicating that cadmium and selenium ions were incorporated into the cell and that the quantum dots were synthesized with intracellular metabolites...
October 20, 2016: Materials
https://www.readbyqxmd.com/read/28738620/proteins-in-microbial-synthesis-of-selenium-nanoparticles
#11
Anna V Tugarova, Alexander A Kamnev
Biogenic formation of nano-sized particles composed of various materials (in particular, selenium) by live microorganisms is widespread in nature. This phenomenon has been increasingly attracting the attention of researchers over the last decade not only owing to a range of diverse applications of such nanoparticles (NPs) in nanobiotechnology, but also because of the specificity of methodologies and mechanisms of NPs formation related to "green synthesis". In this mini-review, recent data are discussed on the multifaceted role of proteins in the processes of microbial reduction of selenium oxyanions and the formation of Se NPs...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28718286/functionalized-selenium-nanosystem-as-radiation-sensitizer-of-125-i-seeds-for-precise-cancer-therapy
#12
Yahui Yang, Qiang Xie, Zhennan Zhao, Lizhen He, Leung Chan, Yingxiang Liu, Yongle Chen, Mingjun Bai, Tao Pan, Yanni Qu, Long Ling, Tianfeng Chen
Although radiotherapy has been extensively applied in cancer treatment, external beam radiation therapy is still unable to avoid damage to adjacent normal tissues in the process of delivering a sufficient radiation dose to the tumor sites of patients. To overcome this limitation, chemoradiotherapy, as a combination of chemotherapy and radiotherapy of a radioactive seed, has been proposed to decrease the damage to tumor-surrounding tissues and enhance the radiosensitivity of solid tumors. In this study, we designed and synthesized folic acid-conjugated selenium nanoparticles (FA@SeNPs) as a cancer-targeting agent that could be synergistically enhanced by radioactive (125)I seeds to realize anticancer efficacy and inhibited colony formation ability...
August 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28714110/poly-vinylpyrollidone-and-selenocysteine-modified-bi2-se3-nanoparticles-enhance-radiotherapy-efficacy-in-tumors-and-promote-radioprotection-in-normal-tissues
#13
Jiangfeng Du, Zhanjun Gu, Liang Yan, Yuan Yong, Xuan Yi, Xiao Zhang, Jing Liu, Renfei Wu, Cuicui Ge, Chunying Chen, Yuliang Zhao
The development of a new generation of nanoscaled radiosensitizers that can not only enhance radiosensitization of tumor tissues, but also increase radioresistance of healthy tissue is highly desirable, but remains a great challenge. Here, this paper reports a new versatile theranostics based on poly(vinylpyrollidone)- and selenocysteine-modified Bi2 Se3 nanoparicles (PVP-Bi2 Se3 @Sec NPs) for simultaneously enhancing radiotherapeutic effects and reducing the side-effects of radiation. The as-prepared nanoparticles exhibit significantly enhanced free-radical generation upon X-ray radiation, and remarkable photothermal effects under 808 nm NIR laser irradiation because of their strong X-ray attenuation ability and high NIR absorption capability...
September 2017: Advanced Materials
https://www.readbyqxmd.com/read/28709020/ruthenium-complexes-polypeptide-self-assembled-nanoparticles-for-identification-of-bacterial-infection-and-targeted-antibacterial-research
#14
Na Huang, Xu Chen, Xufeng Zhu, Mengmeng Xu, Jie Liu
Bacterial infection has been a threat to human health, and so early diagnosis and treatment of bacterial infection is an urgent problem that needs to be solved. In this work, a multifunctional theranostic selenium nanoplatform (Se@PEP-Ru NPs) with early imaging diagnosis and efficient treatment of bacterial infections was designed and constructed. First, the antibacterial peptide UBI29-41 (PEP) was linked to functionalized Selenium nanoparticles (NPs), which enhanced the stability of the antimicrobial peptide and also caused the nanocomposites to specifically target bacterial infection...
July 5, 2017: Biomaterials
https://www.readbyqxmd.com/read/28703339/the-synthesis-and-photophysical-analysis-of-a-series-of-4-nitrobenzochalcogenadiazoles-for-super-resolution-microscopy
#15
Daniel Ray Jenkinson, Ashkey James Cadby, Simon Jones
A series of 4-nitrobenzodiazoles with atomic substitution through the chalcogen group were synthesised and their photophysical properties analysed with a view for use in single-molecule localisation microscopy. Sub-diffraction resolution imaging was achieved for silica nanoparticles coated with each dye. Those containing larger atoms were favoured for super-resolution microscopy due to a reduced blink rate (required for stochastic events to be localised). The sulfur-containing molecule was deemed most amenable for widespread use due to the ease of synthetic manipulation compared to the selenium-containing derivative...
July 13, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28693096/chiral-penicillamine-modified-selenium-nanoparticles-enantioselectively-inhibit-metal-induced-amyloid-%C3%AE-aggregation-for-treating-alzheimer-s-disease
#16
Dongdong Sun, Weiwei Zhang, Qianqian Yu, Xu Chen, Meng Xu, Yanhui Zhou, Jie Liu
Nanometer-scale chirality has gained significant interest from different research fields due to its fundamental importance in nature and living matter. In this study, we design and synthesize chiral penicillamine-capped selenium nanoparticles (l-/d-Pen@Se NPs) that can act as a novel class of chiral amyloid-β (Aβ) inhibitors. In this work, d-Pen@Se NPs demonstrate higher inhibition efficiency, as well as ameliorate cognition and memory impairments. We used rat pheochromocytoma (PC12) cells to perform real-time cell analysis assay (RTCA) to probe the potential cytotoxicity of l-/d-Pen@Se NPs...
November 1, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28691127/selenium-nanoparticles-with-low-level-ionizing-radiation-exposure-ameliorate-nicotine-induced-inflammatory-impairment-in-rat-kidney
#17
Walid E Zahran, Sawsan M Elsonbaty, Fatma S M Moawed
Occupational exposure to low-level ionizing radiation (<1 Gy) was shown to enhance cell protection via attenuating an established inflammatory process. Nicotine, a major toxic component of cigarette smoke, is responsible for smoking-mediated renal dysfunction. The present study was therefore aimed to investigate the protective impact of ginger Zingiber officinale selenium nanoparticles (SeNPs) with whole-body low-dose gamma radiation (γ-R) against nicotine-induced nephrotoxicity in male albino rats. Nicotine intoxication was induced with 0...
July 9, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28685585/the-effects-of-combined-selenium-nanoparticles-and-radiation-therapy-on-breast-cancer-cells-in-vitro
#18
Feng Chen, Xiao Hong Zhang, Xiao Dan Hu, Pei Dang Liu, Hai Qian Zhang
Radiosensitizers that increase cancer cell radio-sensitivity can enhance the effectiveness of irradiation and minimize collateral damage. Nanomaterial has been employed in conjunction with radiotherapy as radiosensitizers, due to its unique physicochemical properties. In this article, we evaluated selenium nanoparticles (Nano-Se) as a new radiosensitizer. Nano-Se was used in conjunction with irradiation on MCF-7 breast cancer cells, and efficacy and mechanisms of this combined treatment approach were evaluated...
July 7, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28684913/preparation-and-antioxidant-properties-of-selenium-nanoparticles-loaded-chitosan-microspheres
#19
Kaikai Bai, Bihong Hong, Jianlin He, Zhuan Hong, Ran Tan
Selenium nanoparticles (SeNPs), as a special form of selenium (Se) supplement, have attracted worldwide attention due to their favorable properties and unique bioactivities. Herein, an eco-friendly and economic way to prepare stable SeNPs is introduced. SeNPs were synthesized in aqueous chitosan (CTS) and then embedded into CTS microspheres by spray-drying, forming selenium nanoparticles-loaded chitosan microspheres (SeNPs-M). The physicochemical properties including morphology, elemental state, size distribution and surface potential were investigated...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28660360/neuro-and-nephrotoxicity-of-subchronic-cadmium-chloride-exposure-and-the-potential-chemoprotective-effects-of-selenium-nanoparticles
#20
Kadry M Sadek, Mohamed A Lebda, Tarek K Abouzed, Sherif M Nasr, Moustafa Shoukry
Cadmium (Cd) exposure leads to production of reactive oxygen species (ROS), which are associated with Cd-induced neurotoxicity and nephrotoxicity. Selenium nanoparticles (Se-NPs) have high bioavailability and antioxidant activities so it attracted wide spread attention. The present study examined the possible ameliorative effect of Se-NPs with diameters of 3-5 nm and 10-20 nm against cadmium chloride (CdCl2)-induced neuro- and nephrotoxicity in rats. Rats were treated with Se-NPs (0 or 0.5 mg/kg BW, s.c...
June 28, 2017: Metabolic Brain Disease
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