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https://www.readbyqxmd.com/read/27933719/depth-profiling-cross-linked-poly-methyl-methacrylate-films-a-tof-sims-approach
#1
Soheila Naderi-Gohar, Kevin M H Huang, Yiliang Wu, Woon Ming Lau, Heng-Yong Nie
RATIONALE: In order to determine the degree of cross-linking on the surface and its variations in a nanometer-scale depth of organic materials, we developed an approach based on time-of-flight secondary ion mass spectrometry (TOF-SIMS), which provides rich chemical information in the form of fragment ions. TOF-SIMS is extremely surface sensitive and capable of depth profiling with the use of a sputter ion beam to remove controllable amounts of substance. METHODS: Poly(methyl methacrylate) (PMMA) films spin-coated on a Si substrate were cross-linked using a recently developed, surface sensitive, hyperthermal hydrogen projectile bombardment technique...
December 9, 2016: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/27933692/preferential-changes-of-skeletal-muscle-echogenicity-in-myotonic-dystrophy-type-1
#2
N Takamatsu, K Sogawa, H Nodera, S Hashiguchi, Y Osaki, M Saito, A Mori, Y Izumi, R Kaji
BACKGROUND AND PURPOSE: In myotonic dystrophy type 1 (DM1), weakness of distal limb muscles affects quality of life. Non-invasive evaluation of muscular involvement by muscle sonography could be useful for characterizing muscle-specific involvement. METHODS: Sonography of the lower leg and forearm was performed in 19 patients with DM1 and 10 control subjects. The mean echo intensities (EIs) of seven limb muscles were obtained by computer-assisted histogram analysis and compared within DM1 according to the overall clinical severity...
December 9, 2016: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27933682/high-efficient-intramolecular-electrochemiluminescence-energy-transfer-for-ultrasensitive-bioanalysis-of-aflatoxin-m1
#3
Jiali Liu, Min Zhao, Ying Zhuo, Yaqin Chai, Ruo Yuan
The intermolecular electrochemiluminescence resonance energy transfer (ECL-RET) between luminol and Ru(bpy)32+ was studied extensively to achieve the sensitive bio-analysis owing to the perfect spectral overlap of the donor and acceptor, but it still suffers from the challenging issue of low energy transfer efficiency. Here, the intramolecular ECL-RET towards the novel ECL compound containing the donor of luminol and the acceptor of Ru(bpy)2(mcbpy)2+ was designed and investigated for the first time (The compound was abbreviated as Lum-Ru)...
December 8, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27933680/primary-breast-angiosarcoma-a-retrospective-study-of-36-cases-from-a-single-chinese-medical-institute-with-clinicopathologic-and-radiologic-correlations
#4
Lei Wang, I Weng Lao, Lin Yu, Wentao Yang, Jian Wang
The aim of this study was to present our experience with primary breast angiosarcoma (PBA) by describing a large series of cases with an emphasis on clinicopathologic and radiologic correlations. Thirty-six cases of PBA diagnosed at our institution between 2006 and 2014 were retrospectively evaluated. All but one case occurred in women with a median age of 35.5 years. The majority of patients presented with a deeply located painless mass, whereas a minority manifested as diffuse enlargement or swelling of the breast...
December 9, 2016: Breast Journal
https://www.readbyqxmd.com/read/27933654/in-vitro-detection-of-diesel-exhaust-particles-induced-human-lung-carcinoma-epithelial-cells-damage-and-the-effect-of-resveratrol
#5
Qifei Li, Mingjie Tang, Anhong Zhou
People are taking up antioxidants in their daily diet and being exposed to a potential diesel exhaust particles (DEP)-containing environment. Thus it is important to study in vitro cellular responses when cells are exposed to DEP with or without antioxidant treatment. The investigation of DEP and resveratrol (RES) on cellular biophysical and biochemical changes is needed to better understand the mechanisms of DEP and RES in mammalian cells. A combination of two non-invasive techniques (atomic force microscopy, AFM, and Raman spectroscopy, RM) and multimodal tools were applied to evaluate the biophysical, biochemical alterations and cytokine, membrane potential and cell cycle of cells with or without RES pretreatment to different times of DEP exposure...
December 9, 2016: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/27933480/alternatives-to-the-baseline-kub-for-ctkub-detected-calculi-evaluation-of-ct-scout-and-average-and-maximum-intensity-projection-images
#6
Hin-Boon Matthew Lew, James Han-Su Seow, Chandra Padmini Hewavitharana, Sally Burrows
PURPOSE: A CT of the kidneys, ureters, and bladder (CTKUB) is the investigation of choice in suspected renal colic. Plain kidney, ureter, and bladder radiographs (KUB) can be used to monitor the progress of a stone if radiographically visible on a baseline KUB. This study aims to determine if a low-dose CT Scout, thick-slab average intensity projection (AIP), or maximum intensity projection (MIP) images are suitable as substitutes for a baseline KUB. METHOD: A retrospective review of patients from a tertiary adult institute that had a positive CTKUB and a KUB within 4 h of the CT was performed...
December 8, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27933447/indian-summer-heat-wave-of-2015-a-biometeorological-analysis-using-half-hourly-automatic-weather-station-data-with-special-reference-to-andhra-pradesh
#7
M A Sarath Chandran, A V M Subba Rao, V M Sandeep, V P Pramod, P Pani, V U M Rao, V Visha Kumari, Ch Srinivasa Rao
Heat wave is a hazardous weather-related extreme event that affects living beings. The 2015 summer heat wave affected many regions in India and caused the death of 2248 people across the country. An attempt has been made to quantify the intensity and duration of heat wave that resulted in high mortality across the country. Half hourly Physiologically Equivalent Temperature (PET), based on a complete heat budget of human body, was estimated using automatic weather station (AWS) data of four locations in Andhra Pradesh state, where the maximum number of deaths was reported...
December 8, 2016: International Journal of Biometeorology
https://www.readbyqxmd.com/read/27933382/the-impact-of-hereditary-multiple-exostoses-on-quality-of-life-satisfaction-global-health-status-and-pain
#8
Riccardo D'Ambrosi, Vincenza Ragone, Camilla Caldarini, Nicola Serra, Federico Giuseppe Usuelli, Renato Mario Facchini
PURPOSE: The aim of the study was to evaluate quality of life (QOL), global health status, pain, and level of satisfaction in patients with hereditary multiple exostoses (HME), and to correlate the association between the severity of diseases and age, sex, number of surgical procedures, and number of exostoses. METHODS: The data of 50 patients with HME were retrospectively evaluated and recorded. QOL was evaluated with the Short-Form Health Survey (SF-12) questionnaire, the 12-Item General Health Questionnaire (GHQ-12), and Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q-SF); intensity of pain was measured using the visual analogue scale (VAS)...
December 8, 2016: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/27933363/spatially-resolved-metabolic-distribution-for-unraveling-the-physiological-change-and-responses-in-tomato-fruit-using-matrix-assisted-laser-desorption-ionization-mass-spectrometry-imaging-maldi-msi
#9
Junya Nakamura, Tomomi Morikawa-Ichinose, Yoshinori Fujimura, Eisuke Hayakawa, Katsutoshi Takahashi, Takanori Ishii, Daisuke Miura, Hiroyuki Wariishi
Information on spatiotemporal metabolic behavior is indispensable for a precise understanding of physiological changes and responses, including those of ripening processes and wounding stress, in fruit, but such information is still limited. Here, we visualized the spatial distribution of metabolites within tissue sections of tomato (Solanum lycopersicum L.) fruit using a matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) technique combined with a matrix sublimation/recrystallization method...
December 8, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27933346/intensive-care-medicine-in-2050-toward-an-intensive-care-unit-without-waste
#10
EDITORIAL
George L Anesi, Jason Wagner, Scott D Halpern
No abstract text is available yet for this article.
December 8, 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/27933323/assessing-collagen-and-micro-permeability-at-the-proanthocyanidin-treated-resin-dentin-interface
#11
Berdan Aydin, Lina Saleh Hassan, Grace Viana, Ana K Bedran-Russo
PURPOSE: To establish a fluorescence-based method to simultaneously assess micro-permeability and collagen cross-linking induced by chemical agents at the resin-dentin interface. MATERIALS AND METHODS: Three chemical agents were investigated (proanthocyanidin-rich grape seed extract: GSE; carbodiimide hydrochloride/N-hydroxysuccinimide: EDC/NHS; glutaraldehyde: GD) along with a control (distilled water) as primers applied on flat occlusal dentin surfaces of 48 teeth and restored with two commercially available etch-and-rinse adhesives...
December 8, 2016: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/27933285/developmental-profile-and-diagnoses-in-children-presenting-with-motor-stereotypies
#12
Francesco Cardona, Francesca Valente, Daniela Miraglia, Caterina D'Ardia, Valentina Baglioni, Flavia Chiarotti
INTRODUCTION: Motor stereotypies represent a typical example of the difficulty in distinguishing non-clinical behaviors (physiological and transient) from symptoms or among different disorders ["primary stereotypies," associated with autistic spectrum disorder (ASD), intellectual disabilities, genetic syndromes, and sensory impairment]. The aim of this study was to obtain an accurate assessment on the relationship between stereotypies and neurodevelopmental disorders. METHODS: We studied 23 children (3 girls), aged 36-95 months, who requested a consultation due to the persistence or increased severity of motor stereotypies...
2016: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/27933180/serum-levels-of-immunoglobulins-and-severity-of-community-acquired-pneumonia
#13
Mari C de la Torre, Pere Torán, Mateu Serra-Prat, Elisabet Palomera, Estel Güell, Ester Vendrell, Joan Carles Yébenes, Antoni Torres, Jordi Almirall
INSTRUCTION: There is evidence of a relationship between severity of infection and inflammatory response of the immune system. The objective is to assess serum levels of immunoglobulins and to establish its relationship with severity of community-acquired pneumonia (CAP) and clinical outcome. METHODS: This was an observational and cross-sectional study in which 3 groups of patients diagnosed with CAP were compared: patients treated in the outpatient setting (n=54), patients requiring in-patient care (hospital ward) (n=173), and patients requiring admission to the intensive care unit (ICU) (n=191)...
2016: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/27933158/development-and-implementation-of-a-standardized-pathway-in-the-pediatric-intensive-care-unit-for-children-with-severe-traumatic-brain-injuries
#14
Lauren Rakes, Mary King, Brian Johnston, Randall Chesnut, Rosemary Grant, Monica Vavilala
Severe traumatic brain injury (TBI) is a leading cause of morbidity and mortality in children. In 2003 and 2012, the Brain Trauma Foundation established and refined evidence-based guidelines for management of severe TBI in children. A recent multicenter study demonstrated an association between TBI guideline adherence and improved discharge survival. However, this study also showed large variation in adherence to pediatric TBI management at our level 1 pediatric trauma center, where overall adherence to fourteen pediatric intensive care unit (PICU) TBI clinical indicators was 64%...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27933142/salidroside-reduces-tau-hyperphosphorylation-via-up-regulating-gsk-3%C3%AE-phosphorylation-in-a-tau-transgenic-drosophila-model-of-alzheimer-s-disease
#15
Bei Zhang, Qiongqiong Li, Xingkun Chu, Suya Sun, Shengdi Chen
BACKGROUND: Alzheimer's disease (AD) is an age-related and progressive neurodegenerative disease that causes substantial public health care burdens. Intensive efforts have been made to find effective and safe treatment against AD. Salidroside (Sal) is the main effective component of Rhodiola rosea L., which has several pharmacological activities. The objective of this study was to investigate the efficacy of Sal in the treatment of AD transgenic Drosophila and the associated mechanisms...
2016: Translational Neurodegeneration
https://www.readbyqxmd.com/read/27933083/the-sclerophyllous-eucalyptus-camaldulensis-and-herbaceous-nicotiana-tabacum-have-different-mechanisms-to-maintain-high-rates-of-photosynthesis
#16
Wei Huang, You-Gui Tong, Guo-Yun Yu, Wei-Xian Yang
It is believed that high levels of mesophyll conductance (gm) largely contribute to the high rates of photosynthesis in herbaceous C3 plants. However, some sclerophyllous C3 plants that display low levels of gm have high rates of photosynthesis, and the underlying mechanisms responsible for high photosynthetic rates in sclerophyllous C3 plants are unclear. In the present study, we examined photosynthetic characteristics in two high-photosynthesis plants (the sclerophyllous Eucalyptus camaldulensis and the herbaceous Nicotiana tabacum) using measurements of gas exchange and chlorophyll fluorescence...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27933069/accumulation-and-secretion-of-coumarinolignans-and-other-coumarins-in-arabidopsis-thaliana-roots-in-response-to-iron-deficiency-at-high-ph
#17
Patricia Sisó-Terraza, Adrián Luis-Villarroya, Pierre Fourcroy, Jean-François Briat, Anunciación Abadía, Frédéric Gaymard, Javier Abadía, Ana Álvarez-Fernández
Root secretion of coumarin-phenolic type compounds has been recently shown to be related to Arabidopsis thaliana tolerance to Fe deficiency at high pH. Previous studies revealed the identity of a few simple coumarins occurring in roots and exudates of Fe-deficient A. thaliana plants, and left open the possible existence of other unknown phenolics. We used HPLC-UV/VIS/ESI-MS(TOF), HPLC/ESI-MS(ion trap) and HPLC/ESI-MS(Q-TOF) to characterize (identify and quantify) phenolic-type compounds accumulated in roots or secreted into the nutrient solution of A...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27933050/an-essential-factor-for-high-mg-2-tolerance-of-staphylococcus-aureus
#18
Joshua Armitano, Peter Redder, Vanessa A Guimarães, Patrick Linder
Internal bacterial concentration of Mg(2+), the most abundant divalent cation in living cells, is estimated to be in the single millimolar range. However, many bacteria will thrive in media with only micromolars of Mg(2+), by using a range of intensely studied and highly efficient import mechanisms, as well as in media with very high magnesium concentration, presumably mediated by currently unknown export mechanisms. Staphylococcus aureus has a particularly high Mg(2+) tolerance for a pathogen, growing unimpaired in up to 770 mM Mg(2+), and we here identify SA0657, a key factor in this tolerance...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27933005/social-brain-hypothesis-vocal-and-gesture-networks-of-wild-chimpanzees
#19
Sam G B Roberts, Anna I Roberts
A key driver of brain evolution in primates and humans is the cognitive demands arising from managing social relationships. In primates, grooming plays a key role in maintaining these relationships, but the time that can be devoted to grooming is inherently limited. Communication may act as an additional, more time-efficient bonding mechanism to grooming, but how patterns of communication are related to patterns of sociality is still poorly understood. We used social network analysis to examine the associations between close proximity (duration of time spent within 10 m per hour spent in the same party), grooming, vocal communication, and gestural communication (duration of time and frequency of behavior per hour spent within 10 m) in wild chimpanzees...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27932885/health-behaviors-of-patients-diagnosed-with-type-2-diabetes-mellitus-and-their-influence-on-the-patients-satisfaction-with-life
#20
Anna Rosiek, Tomasz Kornatowski, Natalia Frąckowiak-Maciejewska, Aleksandra Rosiek-Kryszewska, Przemysław Wyżgowski, Krzysztof Leksowski
BACKGROUND: The diagnosis of type 2 diabetes mellitus (T2DM) carries with it a number of changes to the patient's lifestyle. A healthy lifestyle, health and preventive behaviors, as well as healthy nutrition habits play a key role in treating T2DM as well as limiting its complications. MATERIALS AND METHODS: The aim of this study was the analysis of the correlation of T2DM patients' health behaviors and their influence on the patients' quality of life. The study was performed on a group of 50 patients from the Kuyavian-Pomeranian Voivodeship...
2016: Therapeutics and Clinical Risk Management
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