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https://www.readbyqxmd.com/read/29782663/prospective-study-confirms-that-bronchiolitis-in-early-infancy-increases-the-risk-of-reduced-lung-function-at-10-13-years-of-age
#1
Riikka Riikonen, Eero Lauhkonen, Sari Törmänen, Katri Backman, Petri Koponen, Merja Helminen, Kirsi Nuolivirta, Matti Korppi
AIM: This study evaluated children hospitalised for bronchiolitis at less than six months of age to see if they had reduced lung function in early adolescence. METHODS: We have prospectively followed 166 children hospitalised for infant bronchiolitis in 2001-2004 at Tampere University Hospital, Finland. At 10-13 years of age, flow-volume spirometry was measured in 89 cases and 108 controls without infant bronchiolitis from the local population register. Parameters of flow-volume spirometry before and after bronchodilation were analysed...
May 21, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29782063/intrapleural-streptokinase-was-effective-and-safe-for-children-with-multi-loculated-empyema-regardless-of-the-time-from-disease-onset
#2
Joseph L Mathew, Vimlesh Soni, Meenu Singh, Piyush Mittal, Sunit Singhi, Vikas Gautam, Kushaljit S Sodhi, Jayashree Muralidharan, Pankaj Vaidya
AIM: This study compared the efficacy of administering intrapleural streptokinase to children with multi-loculated empyema within 14 days or at any time after disease onset. METHODS: We studied children under 12 years who were admitted to a teaching hospital in Chandigarh, India, from July 2013 to June 2017 with multi-loculated empyema and received antibiotics, pleural drainage and intrapleural streptokinase. The first group only received three doses within 14 days of disease onset, the second received three doses any time after onset and the third group received 4-6 doses any time after onset...
May 21, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29781681/the-management-of-diabetic-ketoacidosis-at-a-rural-regional-hospital-in-kwazulu-natal
#3
Nontobeko F M Ndebele, Mergan Naidoo
BACKGROUND:  Diabetic ketoacidosis (DKA) is a biochemical triad of hyperglycaemia, ketoacidosis and ketonaemia and one of the potentially life-threatening acute metabolic complications of diabetes mellitus. This study aimed at describing the clinical profile of patients presenting with DKA to a busy rural regional hospital in KwaZulu-Natal. METHODS:  A retrospective review of clinical notes of patients presenting with DKA to the Emergency Department was performed over a 10-month period...
March 22, 2018: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/29780034/improving-predictive-asthma-algorithms-with-modelled-environment-data-for-scotland-an-observational-cohort-study-protocol
#4
Ireneous N Soyiri, Aziz Sheikh, Stefan Reis, Kimberly Kavanagh, Massimo Vieno, Tom Clemens, Edward J Carnell, Jiafeng Pan, Abby King, Rachel C Beck, Hester J T Ward, Chris Dibben, Chris Robertson, Colin R Simpson
INTRODUCTION: Asthma has a considerable, but potentially, avoidable burden on many populations globally. Scotland has some of the poorest health outcomes from asthma. Although ambient pollution, weather changes and sociodemographic factors have been associated with asthma attacks, it remains unclear whether modelled environment data and geospatial information can improve population-based asthma predictive algorithms. We aim to create the afferent loop of a national learning health system for asthma in Scotland...
May 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29780032/severe-outcomes-associated-with-respiratory-viruses-in-newborns-and-infants-a-prospective-viral-surveillance-study-in-jordan
#5
Najwa Khuri-Bulos, Lindsey Lawrence, Bhinnata Piya, Li Wang, Christopher Fonnesbeck, Samir Faouri, Asem Shehabi, Sten H Vermund, John V Williams, Natasha B Halasa
OBJECTIVE: To assess virus-specific hospitalisation rates, risk factors for illness severity and seasonal trends in children hospitalised with acute respiratory infections (ARI). DESIGN: Prospective cohort study. SETTING: A government hospital serving low-income and middle-income population in Amman, Jordan. PARTICIPANTS: Children under 2 years of age hospitalised with fever and/or respiratory symptoms (n=3168) from 16 March 2010 to 31 March 2013...
May 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29779810/association-between-nutritional-blood-based-biomarkers-and-clinical-outcome-in-sarcopenia-patients
#6
Salah Gariballa, Awad Alessa
BACKGROUND: Although several micronutrients deficiency were reported to be associated with poor muscle function, however information on sarcopenia patients is still lacking. The aim of this report was to measure some micronutrients blood-based status in sarcopenia patients during both acute illness and recovery. DESIGN: We assessed nutritional status of randomly selected hospitalised patients using anthropometric, haematological and biochemical data at baseline, 6 weeks and at 6 months...
June 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29777924/views-and-experiences-with-regard-to-antibiotic-use-of-hospitalised-patients-in-five-european-countries-a-qualitative-descriptive-study
#7
V Zanichelli, A A Monnier, G Tebano, M Stanić Benić, I C Gyssens, C Pulcini, V Vlahović-Palčevski, M Schindler, S Harbarth, M Hulscher, B D Huttner
OBJECTIVES: To explore inpatients experiences and views with regard to antibiotics in 5 European hospitals. METHODS: Qualitative study where a patient-centred framework was used to explore inpatients' experiences concerning antibiotic treatment. A purposeful sample of inpatients treated with antibiotics in 5 hospitals (Belgium-BE, Croatia-HR, France-FR, Netherlands-NL, Switzerland-CH) participated in interviews (all centres) and focus groups (CH). RESULTS: 31 interviews (BE=5, HR=10, F=9, NL=5, CH=2) and three focus groups (CH= 11 participants) were performed...
May 16, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29777882/factors-predicting-hypocalcemia-after-total-thyroidectomy-a-retrospective-cohort-analysis
#8
Claudius Falch, Jan Hornig, Moritz Senne, Manuel Braun, Alfred Konigsrainer, Andreas Kirschniak, Sven Muller
BACKGROUND: Hypocalcemia after total thyroidectomy is the most frequent complication resulting in prolongation of hospitalisation. Therefore we aimed to analyse clinical risk factors predictive for hypocalcemia and its long term persistence after total thyroidectomy. METHODS: Retrospective analysis of patients undergoing total thyroidectomy from 2005 until 2013. Outcome measures were initial postoperative hypocalcemia defined as serum calcium below 2.0 mmol/l after total thyroidectomy within 48 h and persistent hypocalcemia defined as serum calcium below 2...
May 16, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29777264/empagliflozin-reduces-cardiovascular-events-mortality-and-renal-events-in-participants-with-type-2-diabetes-after-coronary-artery-bypass-graft-surgery-subanalysis-of-the-empa-reg-outcome%C3%A2-randomised-trial
#9
Subodh Verma, C David Mazer, David Fitchett, Silvio E Inzucchi, Egon Pfarr, Jyothis T George, Bernard Zinman
AIMS/HYPOTHESIS: After coronary artery bypass graft (CABG) surgery in individuals with type 2 diabetes, there remains a considerable residual cardiovascular risk. In the EMPA-REG OUTCOME® trial in participants with type 2 diabetes and established cardiovascular disease, empagliflozin reduced the risk of cardiovascular death by 38%, all-cause mortality by 32%, hospitalisation for heart failure by 35% and incident or worsening nephropathy by 39% vs placebo when given in addition to standard of care...
May 19, 2018: Diabetologia
https://www.readbyqxmd.com/read/29777042/rates-of-infection-after-colonoscopy-and-osophagogastroduodenoscopy-in-ambulatory-surgery-centres-in-the-usa
#10
Peiqi Wang, Tim Xu, Saowanee Ngamruengphong, Martin A Makary, Anthony Kalloo, Susan Hutfless
OBJECTIVE: Over 15 million colonoscopies and 7 million osophagogastroduodenoscopies (OGDs) are performed annually in the USA. We aimed to estimate the rates of infections after colonoscopy and OGD performed in ambulatory surgery centres (ASCs). DESIGN: We identified colonoscopy and OGD procedures performed at ASCs in 2014 all-payer claims data from six states in the USA. Screening mammography, prostate cancer screening, bronchoscopy and cystoscopy procedures were comparators...
May 18, 2018: Gut
https://www.readbyqxmd.com/read/29776972/improving-serum-calcium-test-ordering-according-to-a-decision-algorithm
#11
Daniel K Faria, Leandro U Taniguchi, Luiz A M Fonseca, Mario Ferreira-Junior, Francisco J B Aguiar, Arnaldo Lichtenstein, Nairo M Sumita, Alberto J S Duarte, Maria M Sales
AIM: To detect differences in the pattern of serum calcium tests ordering before and after the implementation of a decision algorithm. METHODS: We studied patients admitted to an internal medicine ward of a university hospital on April 2013 and April 2016. Patients were classified as critical or non-critical on the day when each test was performed. Adequacy of ordering was defined according to adherence to a decision algorithm implemented in 2014. RESULTS: Total and ionised calcium tests per patient-day of hospitalisation significantly decreased after the algorithm implementation; and duplication of tests (total and ionised calcium measured in the same blood sample) was reduced by 49%...
May 18, 2018: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29776575/optimal-long-term-antithrombotic-treatment-of-patients-with-stable-coronary-artery-disease-and-atrial-fibrillation-oltat-registry
#12
Q Fischer, J L Georges, C Le Feuvre, A Sharma, N Hammoudi, E Berman, S Cohen, I Jolivet, J Silvain, G Helft
BACKGROUND: The optimal long-term antithrombotic treatment of patients with stable coronary artery disease (CAD) and atrial fibrillation (AF) is a challenge in daily practice. We sought to determine the prevalence of hemorrhagic complications and ischaemic events depending on antithrombotic strategy in patients with stable CAD and AF. METHODS: The primary outcome was major adverse cardiac and cerebrovascular events (MACCE) defined as a composite of cardiovascular mortality, myocardial infarction and ischaemic stroke...
August 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29776431/validation-of-verbal-autopsy-methods-using-hospital-medical-records-a-case-study-in-vietnam
#13
Hong Thi Tran, Hoa Phuong Nguyen, Sue M Walker, Peter S Hill, Chalapati Rao
BACKGROUND: Information on causes of death (COD) is crucial for measuring the health outcomes of populations and progress towards the Sustainable Development Goals. In many countries such as Vietnam where the civil registration and vital statistics (CRVS) system is dysfunctional, information on vital events will continue to rely on verbal autopsy (VA) methods. This study assesses the validity of VA methods used in Vietnam, and provides recommendations on methods for implementing VA validation studies in Vietnam...
May 18, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29776002/the-chaos-of-hospitalisation-for-patients-with-critical-limb-ischaemia-approaching-major-amputation
#14
Susan Monaro, Sandra West, Jana Pinkova, Janice Gullick
AIMS AND OBJECTIVES: To illuminate the hospital experience for patients and families when major amputation has been advised for critical limb ischaemia (CLI). BACKGROUND: CLI creates significant burden to the health system and the family, particularly as the person with CLI approaches amputation. Major amputation is often offered as a late intervention for CLI in response to the marked deterioration of an ischaemic limb, and functional decline from reduced mobility, intractable pain, infection and/or toxaemia...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29775978/-initiating-a-robotic-program-for-abdominal-surgery-experiences-from-a-centre-in-germany
#15
Maximilian Brunner, Klaus Matzel, Archil Aladashvili, Christian Krautz, Robert Grützmann, Roland Croner
PURPOSE: Robotic systems are becoming increasingly important in abdominal surgery. We describe the implementation of a robotic program at a German centre for abdominal surgery, with focus on feasibility, safety, patient selection, learning curves, financial aspects and the lessons learned. METHODS: This retrospective analysis covered data on patient demographics, intra- and postoperative parameters, oncological results and costs of all robotic-assisted abdominal operations performed at our institution between August 2012 to December 2016...
May 18, 2018: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29771899/excess-cost-and-inpatient-stay-of-treating-deep-spinal-surgical-site-infections
#16
James Barnacle, Dianne Wilson, Christopher Little, Christopher Hoffman, Nigel Raymond
AIM: To determine the excess cost and hospitalisation associated with surgical site infections (SSI) following spinal operations in a New Zealand setting. METHODS: We identified inpatients treated for deep SSI following primary or revision spinal surgery at a regional tertiary spinal centre between 2009 and 2016. Excess cost and excess length of stay (LOS) were calculated via a clinical costing system using procedure-matched controls. RESULTS: Twenty-eight patients were identified...
May 18, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29771897/is-general-practice-identification-of-prior-cardiovascular-disease-at-the-time-of-cvd-risk-assessment-accurate-and-does-it-matter
#17
Sue Wells, Katrina Poppe, Vanessa Selak, Andrew Kerr, Romana Pylypchuk, Billy Wu, Wing Cheuk Chan, Corina Grey, Suneela Mehta, Dudley Gr Gentles, Rod Jackson
AIMS: To determine the accuracy of general practice recording of prior cardiovascular disease (CVD) at the time of CVD risk assessment and whether recording impacts on CVD management. METHODS: Prior CVD status entered at the time of a first CVD risk assessment from 2002-2015 was compared to prior ischaemic CVD hospitalisations from national datasets using anonymous linkage with an encrypted National Health Index identifier. Clinical factors associated with inaccurate recording of prior events were identified using multivariable logistic regression...
May 18, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29770560/how-nurses-restore-and-maintain-mobility-in-hospitalised-older-people-an-integrative-literature-review
#18
Stephanie Constantin, Sherry Dahlke
AIM: The aim of this integrative review of the literature was to evaluate and summarise current research about how nurses maintain and improve hospitalised older peoples' mobility levels. BACKGROUND: Older persons make up the majority of healthcare recipients, and they are at risk to experience significant decline in their mobility once hospitalised. This can result in longer hospitalisations or nursing home admissions. Currently, it is not well understood how nurses maintain and restore mobility of hospitalised older persons...
May 17, 2018: International Journal of Older People Nursing
https://www.readbyqxmd.com/read/29769253/effectiveness-of-23-valent-pneumococcal-polysaccharide-vaccine-on-elderly-long-term-cancer-survivors-a-population-based-propensity-score-matched-cohort-study
#19
Wen-Yen Chiou, Moon-Sing Lee, Shih-Kai Hung, Hon-Yi Lin, Yuan-Chen Lo, Feng-Chun Hsu, Shiang-Jiun Tsai, Chung-Yi Li
OBJECTIVE: The Advisory Committee on Immunization Practices in 2012 recommended the 23-valent pneumococcal polysaccharide vaccine (PPSV23) for adults with high risk of pneumonia. However, its effectiveness in cancer survivors has not been investigated. Our aim was to investigate the effectiveness of PPSV23 in these patients. DESIGN: Population-based matched cohort study. SETTING: Claim data were obtained from 1 million people registered with the National Health Insurance Research Database in 1996, and followed to 2010...
May 16, 2018: BMJ Open
https://www.readbyqxmd.com/read/29769091/use-of-health-services-among-international-migrant-children-a-systematic-review
#20
REVIEW
Niina Markkula, Baltica Cabieses, Venla Lehti, Eleonora Uphoff, Sofia Astorga, Francisca Stutzin
BACKGROUND: Migrant children have specific health needs, and may face difficulties in accessing health care, but not enough is known about their health service use. This study aims to describe patterns of use of health services of international migrant children and differences to respective native populations. METHODS: Electronic databases PubMed and Web of Science, references of identified publications, and websites of relevant international agencies were searched...
May 16, 2018: Globalization and Health
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