keyword
https://read.qxmd.com/read/38249173/primary-central-nervous-system-lymphoma-mimicking-the-presentation-of-pituitary-apoplexy-a-case-report
#21
Joao Meira Goncalves, Patricia Polónia, Josué Pereira, Pedro Alberto Silva
Pituitary lymphoma is one of the rare variants of primary central nervous system lymphoma (PCNSL), mostly arising due to the metastatic spread of systemic lymphoma. We report the case of a 69-year-old woman who initially presented to her family physician with a headache but without any other symptoms. The MRI scan revealed a sellar mass consistent with a pituitary macroadenoma. When the patient was referred to our hospital, two weeks later, the symptoms had progressed, comprising complete right-sided ophthalmoplegia and ptosis, with left-sided amaurosis...
December 2023: Curēus
https://read.qxmd.com/read/38229808/covid-19-vaccine-induced-expansion-of-pituitary-adenoma-a-case-report
#22
Worapot Srimanan, Somboon Panyakorn
A pituitary adenoma is an insidious and slow-growing neoplasm of the pituitary gland. No definitive aggravating factors have currently been reported for pituitary adenoma enlargement. Our case demonstrates that the coronavirus disease 2019 (COVID-19) vaccine may be one of the risk factors aggravating tumor expansion. A 60-year-old woman experienced visual loss in her left eye for three days. Eight days before presentation or five days before visual loss, she received the fourth dose of the COVID-19 vaccine...
December 2023: Curēus
https://read.qxmd.com/read/38228894/is-the-oct-a-predictive-tool-to-assess-visual-impairment-in-optic-chiasm-compressing-syndrome%C3%A2-in-pituitary-macroadenoma-a-prospective-longitudinal-study
#23
JOURNAL ARTICLE
Maria Teresa Bozzi, Charles-Henry Mallereau, Julien Todeschi, Seyyid Baloglu, François-Daniel Ardellier, Julia Romann, Léa Trouve, Zsolt Bocsksei, Joffrey Alcazar, Guillaume Dannhoff, Thibault Bahougne, Bernard Goichot, Salvatore Chibbaro, Helene Cebula
Visual dysfunction is a prevalent symptom in patients with non-functioning pituitary macroadenoma (NFPM); the role of OCT in such patients has not been yet determined. This is a prospective longitudinal observational study over a period of 6 years, on 20 patients presenting a radiological compression of the optic chiasma without visual acuity (VA) and visual field (VF) disturbances. The primary endpoint was to evaluate the impact of NFPA on neuro-axonal loss by measuring RNFL thickness using OCT at inclusion (T0), 12 months (T1), 24 months (T2), and 36 months (T3), respectively...
January 17, 2024: Neurosurgical Review
https://read.qxmd.com/read/38222861/dopamine-agonists-as-a-novel-cure-for-autoimmune-diabetes
#24
Shaan Sahota, Lorcan Cooper, Anelia Sirkova, Nemanja Stojanovic
We present a patient who, when treated for macroprolactinoma with a dopamine agonist (DA), was able to stop insulin treatment of his autoimmune diabetes for 2 years. The patient was diagnosed with autoimmune diabetes after presenting to emergency services in diabetic ketoacidosis aged 50 years. On presentation, he had high titers of autoantibodies associated with pancreatic islet cell destruction and a high level of glycated hemoglobin. On review in the endocrinology clinic, he displayed signs and symptoms of hypogonadism...
February 2024: JCEM Case Rep
https://read.qxmd.com/read/38222860/pituitary-macroadenoma-with-macronodular-adrenal-hyperplasia-and-novel-armadillo-repeat-containing-protein-5-armc5-mutation
#25
Shikha Khosla, Farah Alsarraf, Eric S Nylen
We present an unusual case of primary bilateral macronodular adrenal hyperplasia (PBMAH) in a 72-year-old African American man. The patient was found to harbor massively enlarged bilateral adrenal glands on imaging along with mild autonomous cortisol secretion. His workup for PBMAH included leukocyte analysis for the armadillo repeat-containing protein 5 ( ARMC5 ) gene. The test revealed a novel heterozygous somatic ARMC5 mutation. The patient was initially managed conservatively. He subsequently presented with unprovoked bilateral pulmonary emboli...
February 2024: JCEM Case Rep
https://read.qxmd.com/read/38222459/pituitary-apoplexy-as-a-mimicker-of-infectious-meningitis-in-an-adolescent-female-patient
#26
JOURNAL ARTICLE
Justine P Enns, Timour Al-Khindi, Catherine Wu, Mamuka Machaidze, Joowhan Sung
Pituitary apoplexy can cause a chemical meningitis and its mimicry in presentation with infectious meningitis poses a diagnostic challenge. Here we report an 18-year-old woman who presented with acute headache, altered mental status, and cerebral spinal fluid (CSF) pleocytosis, and clinically improved with antibiotics and steroids. Despite an unremarkable head computed tomography scan, brain magnetic resonance imaging showed a pituitary macroadenoma with apoplexy. This is one of the first reports of an adolescent with pituitary apoplexy masquerading as infectious meningitis and underscores the importance of keeping this rare condition, often missed on CT scans, on the differential for CSF pleocytosis...
September 2023: Ann Intern Med Clin Cases
https://read.qxmd.com/read/38217731/rathke-s-cyst-with-xanthogranulomatous-change-or-chronic-cystic-craniopharingioma-a-rare-case
#27
JOURNAL ARTICLE
Gabriele Gaggero, Francesca Vitulli, Antonia Ramaglia, Alice Antico, F Rikki Canevari, Gianluca Piatelli, Diego Criminelli Rossi
A 9-year-old girl presented to our neurosurgery clinic complaining of visual disturbances for a week. Magnetic resonance imaging showed an extensive sellar lesion with suprasellar involvement and compression of the optic chiasm. Based on these findings, a cystic craniopharyngioma, a pituitary macroadenoma and - less likely - a Rathke's cleft cyst were considered as differential diagnoses. In view of the progressive loss of vision, the parents agreed to resection of the lesion through an endoscopic endonasal transtubercular approach, with the aim of a gross total resection...
January 13, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://read.qxmd.com/read/38204241/imaging-features-and-misdiagnosis-of-giant-cerebral-cavernous-malformations
#28
JOURNAL ARTICLE
Mengqiang Xiao, Meng Zhang, Min Lei, Fenghuan Lin, Jun Chen, Jingfeng Liu, Niyuan Luo, Yanxia Chen
BACKGROUND: While cerebral cavernous malformations (CCMs) have been extensively described, few reports have described the imaging appearance of giant CCMs (GCCMs). OBJECTIVE: To describe the imaging characteristics of GCCMs and study the reasons for preoperative misdiagnosis. METHODS: We retrospectively analyzed the data of 12 patients (5 men, 7 women; mean age, 35.23 ± 12.64 years) with histopathologically confirmed GCCMs. Two radiologists analyzed the CT (n = 12) and MRI (n = 10) features: location, number, size, shape, boundary, signal intensity, and enhancement...
January 10, 2024: Current medical imaging
https://read.qxmd.com/read/38194617/prolactinoma-in-postmenopausal-women-a-systematic-review
#29
JOURNAL ARTICLE
Marcela Souza Carneiro, Ticiana Aparecida Alves de Mira, Daniela Angerame Yela, Cristina Laguna Benetti-Pinto
IMPORTANCE: Prolactinomas occurring during the reproductive period exhibit a characteristic behavior. There are, however, gaps in the literature regarding the behavior of these tumors after menopause. OBJECTIVE: This study aimed to review and characterize the influence of menopause on prolactinoma behavior. EVIDENCE REVIEW: A systematic review of observational prospective or retrospective studies and clinical trials on prolactinomas was conducted in two situations: tumors diagnosed in the reproductive period (before menopause), with follow-up in the postmenopausal period, or prolactinomas diagnosed in the postmenopausal period, without language or date restrictions...
February 1, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38190975/secondary-xanthogranulomatous-hypophysitis-mimicking-a-pituitary-macroadenoma-a-case-report
#30
JOURNAL ARTICLE
Salma Salhi, Ibtissem Oueslati, Yasmine Mouelhi, Alia Zehani, Nidhameddine Kchir, Elyes Kamoun, Meriem Yazidi, Melika Chihaoui
Hypophysitis is an extremely rare inflammatory disease that can mimic the clinical and radiological features of a pituitary adenoma. In this case report, we describe a 45-year-old woman with secondary xanthogranulomatous hypophysitis (XGH) who presented with signs of a pituitary macroadenoma. The patient complained of headaches, visual impairment, and amenorrhea-galactorrhea syndrome. Her physical examination was normal. Laboratory investigation revealed corticotropin, thyrotropin, and gonadotropin deficiencies...
January 2024: Journal of International Medical Research
https://read.qxmd.com/read/38164002/clinical-characteristics-and-outcomes-of-prolactinomas-in-children-and-adolescents-a-large-retrospective-cohort-study
#31
JOURNAL ARTICLE
Yiying Yang, Xiaoan Ke, Lian Duan, Hongbo Yang, Fengying Gong, Hui Pan, Linjie Wang, Huijuan Zhu
PURPOSE: To summarize the clinical features, both medication and surgical outcomes of prolactinomas in children and adolescents in a large retrospective cohort from China. METHODS: A cohort of patients with prolactinomas aged ≤20 years at diagnosis between 2012 and 2021 in Peking Union Medical College Hospital were retrospectively analyzed. RESULTS: The cohort comprised 170 patients (115 females and 55 males, median age 16.6 years), with 20...
January 2, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38163969/presurgical-medical-treatment-in-prolactinomas-surgical-implications-and-pathological-characteristics-from-290-cases
#32
JOURNAL ARTICLE
Zhengyuan Chen, Xuefei Shou, Lijin Ji, Haixia Cheng, Ming Shen, Zengyi Ma, Wenqiang He, Zhao Ye, Yichao Zhang, Nidan Qiao, Qilin Zhang, Yongfei Wang
OBJECTIVE: To review experience regarding the treatment of prolactinomas by endoscopic endonasal surgery (EES) focusing on the association between presurgical dopamine agonist (DA) treatment and perioperative outcomes, surgical morbidities, endocrine outcomes and pathological characteristics. METHODS: A single-center series of 290 cases were analyzed retrospectively and clinical data were collected. Intratumoural collagen content was assessed by Masson's trichrome staining...
January 2, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38154481/utility-of-simple-and-non-invasive-strategies-alternative-to-inferior-petrosal-sinus-sampling-and-peripheral-crh-stimulation-in-differential-diagnosis-of-acth-dependent-cushing-syndrome
#33
JOURNAL ARTICLE
Bhawna Attri, Alpesh Goyal, Mani Kalaivani, Devasenathipathy Kandasamy, Yashdeep Gupta, Shipra Agarwal, Shamim A Shamim, Nishikant Damle, Mehar Chand Sharma, Viveka P Jyotsna, Ashish Suri, Nikhil Tandon
We aimed to evaluate the utility of simple, cost-effective, and non-invasive strategies alternative to BIPSS and peripheral CRH stimulation in differential diagnosis of ACTH-dependent CS. We performed ROC analysis to evaluate the performance of various tests for differential diagnosis of ACTH-dependent CS in our cohort (CD, n=76 and EAS, n=23) and derived their optimal cut-offs. Subsequently, combining various demographic (gender), clinical (hypokalemia), biochemical (plasma ACTH, HDDST, peripheral CRH stimulation) and imaging (MRI pituitary) parameters, we derived non-invasive models with 100% PPV for CD...
December 28, 2023: Hormone and Metabolic Research
https://read.qxmd.com/read/38117724/-pituitary-cryptococcoma-a-strange-case-of-secondary-granulomatous-hypophysitis
#34
Julio C Rotondaro, Celeste Bettaza, Dolores Clifton Goldney, Gabriela Martinez, Leonardo Paz, Carla Gazzi, Santiago González Abbati, Mariano Tarnogol, Silvia Miguel, Ariel Iungman
Hypophysitis is a pathology with low incidence and prevalence. Likewise, deep fungal infections in immunocompetent patients also represent a rare phenomenon. Even rarer is the case described below, where these two mentioned elements are combined, namely: pituitary cryptococcoma or granulomatous hypophysitis caused by said pathogen in a host without altered immune response. After research in PubMed, there are limited cases in the medical literature of granulomatous hypophysitis caused by Cryptococcus spp., which simulated a pituitary macroadenoma by clinical and imaging manifestations...
2023: Medicina
https://read.qxmd.com/read/38098557/pituitary-macroadenoma-with-panhypopituitarism-masquerading-as-schizophrenia-a-diagnostic-dilemma-managed-conservatively
#35
Sagun Ghimire, Suman Simkhada, Saroj Sah, Amit Subedi
INTRODUCTION AND IMPORTANCE: Secretory pituitary macroadenoma also known as prolactinoma are benign neoplasm comprising very minimal cases of intracranial masses. Among the various presentation suggestive of panhypopituitarism, psychosis, and features of schizophrenia is very rarely seen. In the majority of cases, neurosurgical intervention for the excision of tumor is considered a standard treatment modality but conservative management with dopamine agonist and steroids have also been shown to provide an optimal level of care also improving the quality of level of patient...
December 2023: Annals of Medicine and Surgery
https://read.qxmd.com/read/38098129/an-audit-of-the-use-of-ct-pituitary-scans-to-exclude-a-pituitary-macroadenoma
#36
JOURNAL ARTICLE
Lisa Douglas, James Caldwell, Mark Bolland
BACKGROUND: Pituitary imaging is often required to exclude an adenoma suspected clinically or biochemically. Although magnetic resonance (MR) is the gold standard, computerised tomography (CT) is faster, cheaper and induces less claustrophobia. Our audit at Auckland City Hospital, New Zealand, investigated whether the use of CT of the pituitary as the first line imaging to assess for a pituitary macroadenoma reduces the need for MR. METHODS: We investigated the usefulness of CT pituitary imaging in the exclusion of pituitary macroadenoma between 2012 and 2020...
December 15, 2023: Clinical Diabetes and Endocrinology
https://read.qxmd.com/read/38091700/the-role-of-surgical-management-for-prolactin-secreting-tumors-in-the-era-of-dopaminergic-agonists-an-international-multicenter-report
#37
JOURNAL ARTICLE
Matthew C Findlay, Mohammadmadhi Sabahi, Mohammed Azab, Richard Drexler, Roman Rotermund, Franz L Ricklefs, Jörg Flitsch, Timothy R Smith, John L Kilgallon, Jürgen Honegger, Isabella Nasi-Kordhishti, Paul A Gardner, Zachary C Gersey, Hussein M Abdallah, John A Jane, Ulrich J Knappe, Nesrin Uksul, Henry W S Schroder, Márton Eördögh, Marco Losa, Pietro Mortini, Rüdiger Gerlach, Apio C M Antunes, William T Couldwell, Karol P Budohoski, Robert C Rennert, Michael Karsy
OBJECTIVE: First-line prolactin-secreting tumor (PST) management typically involves treatment with dopamine agonists and the role of surgery remains to be further explored. We examined the international experience of 12 neurosurgical centers to assess the patient characteristics, safety profile, and effectiveness of surgery for PST management. METHODS: Patients surgically treated for PST from January 2017 through December 2020 were evaluated for surgical characteristics, outcomes, and safety...
December 10, 2023: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/38064148/cabergoline-treatment-for-surgery-na%C3%A3-ve-non-functioning-pituitary-macroadenomas
#38
JOURNAL ARTICLE
Irit Ayalon-Dangur, Adi Turjeman, Dania Hirsch, Eyal Robenshtok, Gloria Tsvetov, Alexander Gorshtein, Hiba Masri, Ilana Shraga-Slutzky, Yossi Manisterski, Amit Akirov, Ilan Shimon
PURPOSE: The treatment strategy of non-functioning pituitary adenomas (NFPAs) includes surgery, radiotherapy, medical therapy, or observation without intervention. Cabergoline, a dopaminergic agonist, was suggested for the treatment of NFPA remnants after trans-sphenoidal surgery. This study investigates the efficacy of cabergoline in surgery-naive patients with NFPA. METHODS: Retrospective cohort study including surgery-naive patients with NFPA ≥ 10 mm, treated with cabergoline at a dose of ≥ 1 mg/week for at least 24 months...
December 8, 2023: Pituitary
https://read.qxmd.com/read/38056042/the-clinical-presentation-of-pit1-positive-pituitary-neuroendocrine-tumor-immunonegative-for-growth-hormone-prolactin-and-thyroid-stimulating-hormone-with-analysis-of-clinical-and-immunostaining-dissociation
#39
JOURNAL ARTICLE
Sukwoo Hong, Yuki Shinya, Jorge A Trejo-Lopez, Lucinda M Gruber, Dana Erickson, Bernard R Bendok, Kaisorn L Chaichana, John L Atkinson, Michael J Marino, Angela M Donaldson, Janalee K Stokken, Sydney A Westphal, Alice Y Chang, Susan L Samson, Garret W Choby, Jamie J Van Gompel
BACKGROUND: PIT1 is a pituitary transcription factor that is associated with either growth hormone (GH), prolactin (PRL), or thyroid-stimulating hormone (TSH) production. However, PIT1-positive pituitary neuroendocrine tumors (PitNETs) are occasionally immunonegative for GH, PRL, and TSH. This paper describes the clinical presentation of PIT1 positive however immunonegative PitNETs. METHODS: We conducted a retrospective analysis, identifying 228 PIT1-positive PitNET patients between 2017 and 2022...
November 30, 2023: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/38054230/predictors-of-postoperative-remission-of-acromegaly-experience-of-the-burdenko-neurosurgical-center
#40
JOURNAL ARTICLE
L I Astafyeva, A N Shkarubo, I V Chernov, S R Ibrahim, I N Badmaeva, Yu V Strunina, I A Ilovayskaya, V S Pronin, Yu G Sidneva, P L Kalinin
BACKGROUND: Treatment of acromegaly is still an unresolved problem. Overall postoperative remission rate ranges from 34 to 85%. These values are better for microadenomas (75-90%) and worse for macroadenomas (45-70%). Identification of predictors of acromegaly remission after surgical treatment is an urgent objective to improve the quality of medical care for these patients. OBJECTIVE: To analyze postoperative freedom from acromegaly and predictors of remission. MATERIAL AND METHODS: A retrospective single-center study included 227 patients with acromegaly who underwent resection of pituitary adenoma between August 2018 and August 2021...
2023: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
keyword
keyword
60740
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.