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https://www.readbyqxmd.com/read/28531770/treatment-consumption-and-treatment-re-enrollment-in-ghb-dependent-patients-in-the-netherlands
#1
Martijn S van Noorden, Ton Mol, Jeroen Wisselink, Wil Kuijpers, Boukje A G Dijkstra
BACKGROUND: The objective of this study was to assess treatment consumption and re-enrollment in treatment in patients with gamma-hydroxybutyrate (GHB)-dependence in Dutch Addiction Treatment Centers (ATCs) in comparison with other addictions. METHODS: A cohort-study using nationwide administrative data from regular Dutch ATCs associated with the Dutch National Alcohol and Drugs Information System (LADIS), covering an estimated 95% of ATCs. We selected in- and out-patients with alcohol, drug and/or behavioral addictions with a first treatment episode in 2008-2011 and consecutive treatments until 2013 (n=71,679)...
May 16, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28528373/the-association-between-primary-source-of-healthcare-coverage-and-colorectal-cancer-screening-among-us-veterans
#2
Folasade P May, Elizabeth M Yano, Dawn Provenzale, W Neil Steers, Donna L Washington
BACKGROUND: Colorectal cancer (CRC) is a deadly but largely preventable disease. Screening improves outcomes, but screening rates vary across healthcare coverage models. In the Veterans Health Administration (VA), screening rates are high; however, it is unknown how CRC screening rates compare for Veterans with other types of healthcare coverage. AIMS: To determine whether Veterans with Veteran-status-related coverage (VA, military, TRICARE) have higher rates of CRC screening than Veterans with alternate sources of healthcare coverage...
May 20, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28528243/overvalued-ideation-in-adolescents-with-obsessive-compulsive-disorder
#3
Tania Borda, Fugen Neziroglu, William Taboas, Dean McKay, Leah Frenkiel
In Obsessive Compulsive Disorder (OCD), overvalued ideas (OVI) are considered poor prognostic indicators in adults. To date, OVI has not been studied in an adolescent population with OCD, nor has it been examined in relation to obsessive-compulsive beliefs. To investigate the relationship between OVI and specific cognitions, fifty-five adolescents with OCD (35 male; 20 female; age range 13-17 years; M=14.05 years, SD=1.75 years) participated. It was predicted that OVI would be associated with symptom severity and would moderate obsessive-compulsive beliefs and functional disability...
May 3, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28527693/two-hit-model-of-schizophrenia-induced-by-neonatal-immune-activation-and-peripubertal-stress-in-rats-study-of-sex-differences-and-brain-oxidative-alterations
#4
Aline Santos Monte, Bruna Stefânia Ferreira Mello, Vládia Célia Moreira Borella, Tatiane da Silva Araujo, Francisco Eliclécio Rodrigues da Silva, Francisca Cléa F de Sousa, Antônio Carlos Pinheiro de Oliveira, Clarissa Severino Gama, Mary V Seeman, Silvânia Maria Mendes Vasconcelos, David Freitas De Lucena, Danielle Macêdo
Schizophrenia is considered to be a developmental disorder with distinctive sex differences. Aiming to simulate the vulnerability of the third trimester of human pregnancy to the developmental course of schizophrenia, an animal model was developed, using neonatal poly(I:C) as a first-hit, and peripubertal stress as a second-hit, i.e. a two-hit model. Since, to date, there have been no references to sex differences in the two-hit model, our study sought to determine sex influences on the development of behavior and brain oxidative change in adult rats submitted to neonatal exposure to poly(I:C) on postnatal days 5-7 as well as peripubertal unpredictable stress (PUS)...
May 17, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28527003/the-effects-of-kanizsa-contours-on-temporal-integration-and-attention-in-rapid-serial-visual-presentation
#5
Aytaç Karabay, Elkan G Akyürek
Performance in rapid serial visual presentation tasks has been shown to depend on the temporal integration of target stimuli when they are presented in direct succession. Temporal target integration produces a single, combined representation of visually compatible stimuli, which is comparatively easy to identify. It is currently unknown to what extent target compatibility affects this perceptual behavior, because it has not been studied systematically to date. In the present study, the effects of compatibility on temporal integration and attention were investigated by manipulating the Gestalt properties of target features...
May 19, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/28526994/adolescent-s-health-behaviors-and-risk-for-insulin-resistance-a-review-of-the-literature
#6
REVIEW
Jill L Kaar, Stacey L Simon, Sarah J Schmiege, Kristen J Nadeau, Megan M Kelsey
PURPOSE OF REVIEW: One-third of US adolescents are obese, and related comorbidities exist in this population. Preventing early indicators of these diseases, such as insulin resistance (IR), may impact future morbidity and mortality. Interventions to date have only focused on diet or exercise. Additional targets to prevent disease are needed. This paper reviews the evidence in adolescents examining multiple health behaviors that have been associated with IR. RECENT FINDINGS: Health behaviors (i...
July 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28526289/the-howieson-s-poort-fauna-from-sibudu-cave-documenting-continuity-and-change-within-middle-stone-age-industries
#7
Jamie L Clark
The Howieson's Poort (HP; ∼65-59 ka) continues to be a source of interest to scholars studying human behavioral evolution during the Late Pleistocene. This is in large part because the HP preserves evidence for a suite of innovative technologies and behaviors (including geometric backed tools and engraved ostrich eggshell), but also because the disappearance of the innovative behaviors associated with this phase is not well understood. Here, I present taphonomic and taxonomic data on the full sample of macromammal remains excavated from the HP deposits at Sibudu Cave under the direction of Lyn Wadley...
June 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28526035/microblogging-violent-attacks-on-medical-staff%C3%A2-in-china-a-case-study-of-the-longmen-county-people-s-hospital-incident
#8
Jia Tian, Li Du
BACKGROUND: A violent attack on medical staff in Guangdong Province, in which a female doctor at Longmen County People's Hospital (LCPH) was severely injured by a knife-wielding patient, has drawn significant public attention to the phenomenon of hospital violence and initiated discussions on how to resolve violence in hospitals. Social networking sites, such as Sina Weibo, a Chinese version of Twitter, have played a role in this public debate. The incident at LCPH provides an opportunity to examine how Weibo has been used in the debate about violence against medical staff in China...
May 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28524006/circulating-tumor-cells-a-reliable-biomarker-for-prostate-cancer-treatment-assessment
#9
Chiara Ciccarese, Rodolfo Montironi, Michelangelo Fiorentino, Guido Martignoni, Matteo Brunelli, Roberto Iacovelli, Antonio Lopez-Beltran, Liang Cheng, Marina Scarpelli, Holger Moch, Giampaolo Tortora, Francesco Massari
Prostate cancer is a common malignancy with highly molecular heterogeneity responsible for a wide spectrum of clinical behavior. To date, several treatment options are available, whose selection is currently based mainly on clinical criteria. Given the weakness of conventional imaging and PSA assay, the identification of a prognostic and predictive biomarker for choosing the appropriate treatment and monitoring its efficacy is a very topical issue in prostate cancer management. Circulating tumor cells (CTCs) have substantial promise for early tumor diagnosis, disease recurrence and metastatic spread monitoring as well as for biological tumor characterization, thus representing a reliable translational real-time biomarkers of prostate cancer...
May 18, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/28520796/a-hierarchical-model-for-estimating-the-spatial-distribution-and-abundance-of-animals-detected-by-continuous-time-recorders
#10
Robert M Dorazio, K Ullas Karanth
MOTIVATION: Several spatial capture-recapture (SCR) models have been developed to estimate animal abundance by analyzing the detections of individuals in a spatial array of traps. Most of these models do not use the actual dates and times of detection, even though this information is readily available when using continuous-time recorders, such as microphones or motion-activated cameras. Instead most SCR models either partition the period of trap operation into a set of subjectively chosen discrete intervals and ignore multiple detections of the same individual within each interval, or they simply use the frequency of detections during the period of trap operation and ignore the observed times of detection...
2017: PloS One
https://www.readbyqxmd.com/read/28520768/mobile-phone-reminders-and-peer-counseling-improve-adherence-and-treatment-outcomes-of-patients-on-art-in-malaysia-a-randomized-clinical-trial
#11
Surajudeen Abiola Abdulrahman, Lekhraj Rampal, Faisal Ibrahim, Anuradha P Radhakrishnan, Hayati Kadir Shahar, Norlijah Othman
BACKGROUND: Adherence to treatment remains the cornerstone of long term viral suppression and successful treatment outcomes among patients receiving Antiretroviral Therapy (ART). OBJECTIVE(S): Evaluate the effectiveness of mobile phone reminders and peer counseling in improving adherence and treatment outcomes among HIV positive patients on ART in Malaysia. METHODS: A single-blind, parallel group RCT conducted in Hospital Sungai Buloh, Malaysia in which 242 adult Malaysian patients were randomized to intervention or control groups...
2017: PloS One
https://www.readbyqxmd.com/read/28520745/high-handaxe-symmetry-at-the-beginning-of-the-european-acheulian-the-data-from-la-noira-france-in-context
#12
Radu Iovita, Inbal Tuvi-Arad, Marie-Hélène Moncel, Jackie Despriée, Pierre Voinchet, Jean-Jacques Bahain
In the last few decades, new discoveries have pushed the beginning of the biface-rich European Acheulian from 500 thousand years (ka) ago back to at least 700 ka, and possibly to 1 million years (Ma) ago. It remains, however, unclear to date if handaxes arrived in Europe as a fully developed technology or if they evolved locally from core-and-flake industries. This issue is also linked with another long-standing debate on the existence and behavioral, cognitive, and social meaning of a possibly chronological trend for increased handaxe symmetry throughout the Lower Paleolithic...
2017: PloS One
https://www.readbyqxmd.com/read/28518189/structure-and-dynamics-of-water-confined-in-a-graphene-nanochannel-under-gigapascal-high-pressure-dependence-of-friction-on-pressure-and-confinement
#13
Lei Yang, Yanjie Guo, Dongfeng Diao
Recently, water flow confined in nanochannels has become an interesting topic due to its unique properties and potential applications in nanofluidic devices. The trapped water is predicted to experience high pressure in the gigapascal regime. Theoretical and experimental studies have reported various novel structures of the confined water under high pressure. However, the role of this high pressure on the dynamic properties of water has not been elucidated to date. In the present study, the structure evolution and interfacial friction behavior of water constrained in a graphene nanochannel were investigated via molecular dynamics simulations...
May 18, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28516856/dating-violence-perpetration-associations-with-early-maladaptive-schemas
#14
Ryan C Shorey, Catherine Strauss, Heather Zapor, Gregory L Stuart
Violence between dating couples is a serious and prevalent problem among college students (Shorey, Cornelius, & Bell, 2008). Social-cognitive theories of aggression (e.g., Berkowitz, 1990) propose that perpetrators may have more maladaptive cognitive schemas that increase risk for aggression than non-perpetrators. Thus, this study examined differences between perpetrators and non-perpetrators of dating violence on early maladaptive schemas, which are rigidly held cognitive and behavioral patterns that guide how individuals encode and respond to stimuli in their environments (Young, Klosko, & Weishaar, 2003)...
May 17, 2017: Violence and Victims
https://www.readbyqxmd.com/read/28516324/bacterial-intelligence-imitation-games-time-sharing-and-long-range-quantum-coherence
#15
REVIEW
Sarangam Majumdar, Sukla Pal
Bacteria are far more intelligent than we can think of. They adopt different survival strategies to make their life comfortable. Researches on bacterial communication to date suggest that bacteria can communicate with each other using chemical signaling molecules as well as using ion channel mediated electrical signaling. Though in past few decades the scopes of chemical signaling have been investigated extensively, those of electrical signaling have received less attention. In this article, we present a novel perspective on time-sharing behavior, which maintains the biofilm growth under reduced nutrient supply between two distant biofilms through electrical signaling based on the experimental evidence reported by Liu et al...
May 17, 2017: Journal of Cell Communication and Signaling
https://www.readbyqxmd.com/read/28515834/better-health-related-fitness-in-youth-implications-for-public-health-guidelines
#16
Mitch Barton, Allen W Jackson, Scott B Martin, James R Morrow, Trent A Petrie, Christy A Greenleaf
Public health guidelines for physical activity (PA) behaviors are being updated with 2018 as a proposed release date. Currently, ≥60 minutes of daily PA are recommended for youth. Thus, the purpose of this study was to investigate the association between reported days of aerobic PA and health-related fitness (HRF). Participants included 4448 students in grades 6-8. Self-reported days of ≥60 minutes of aerobic PA was obtained. HRF was assessed with FitnessGram. Discriminant analysis indicated that weekly days of aerobic PA related to HRF...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28514943/sex-differences-underlying-orofacial-varicella-zoster-associated-pain-in-rats
#17
Crystal Stinson, Mohong Deng, Michael B Yee, Larry L Bellinger, Paul R Kinchington, Phillip R Kramer
BACKGROUND: Most people are initially infected with varicella zoster virus (VZV) at a young age and this infection results in chickenpox. VZV then becomes latent and reactivates later in life resulting in herpes zoster (HZ) or "shingles". Often VZV infects neurons of the trigeminal ganglia to cause ocular problems, orofacial disease and occasionally a chronic pain condition termed post-herpetic neuralgia (PHN). To date, no model has been developed to study orofacial pain related to varicella zoster...
May 17, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28513849/surgical-considerations-for-papillary-thyroid-microcarcinomas
#18
REVIEW
Laura Boucai, Victor Bernet, Ashok Shaha, Maisie L Shindo, Brendan C Stack, Robert M Tuttle
We reevaluate current treatment recommendations of papillary thyroid microcarcinomas taking into account the indolent behavior of these tumors, and the potential morbidity that may result from an unnecessary surgery. The goals of this communication are to: 1) provide surgeons and endocrinologists with the most up-to-date evidence on management of microcarcinomas, 2) outline appropriate instances for active surveillance, and 3) describe the role of surgical interventions for microcarcinomas including lobectomy, total thyroidectomy, and central neck dissection...
May 17, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28510054/design-and-development-of-genetically-encoded-fluorescent-sensors-to-monitor-intracellular-chemical-and-physical-parameters
#19
REVIEW
Arno Germond, Hideaki Fujita, Taro Ichimura, Tomonobu M Watanabe
Over the past decades many researchers have made major contributions towards the development of genetically encoded (GE) fluorescent sensors derived from fluorescent proteins. GE sensors are now used to study biological phenomena by facilitating the measurement of biochemical behaviors at various scales, ranging from single molecules to single cells or even whole animals. Here, we review the historical development of GE fluorescent sensors and report on their current status. We specifically focus on the development strategies of the GE sensors used for measuring pH, ion concentrations (e...
June 2016: Biophysical Reviews
https://www.readbyqxmd.com/read/28508300/the-symbolic-nature-of-trust-in-heterosexual-adolescent-romantic-relationships
#20
Jerika C Norona, Deborah P Welsh, Spencer B Olmstead, Chloe F Bliton
Trust contributes to young people's capacity for sustaining current and future successful relationships. To date, research has yet to examine the meaning of trust in early dating relationships and reasons for its deterioration. The present study focused on video-recorded conversations about trust between 34 heterosexual adolescent couples in dating relationships living in the U.S. Transcripts from these conversations were qualitatively analyzed using thematic analysis to identify adolescents' meanings of trust and reasons they provided for a lack of trust in their romantic partners...
May 15, 2017: Archives of Sexual Behavior
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