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Psychiatric Epidemiology

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https://www.readbyqxmd.com/read/28746715/identification-of-genetic-loci-jointly-influencing-schizophrenia-risk-and-the-cognitive-traits-of-verbal-numerical-reasoning-reaction-time-and-general-cognitive-function
#1
Olav B Smeland, Oleksandr Frei, Karolina Kauppi, W David Hill, Wen Li, Yunpeng Wang, Florian Krull, Francesco Bettella, Jon A Eriksen, Aree Witoelar, Gail Davies, Chun C Fan, Wesley K Thompson, Max Lam, Todd Lencz, Chi-Hua Chen, Torill Ueland, Erik G Jönsson, Srdjan Djurovic, Ian J Deary, Anders M Dale, Ole A Andreassen
Importance: Schizophrenia is associated with widespread cognitive impairments. Although cognitive deficits are one of the factors most strongly associated with functional outcome in schizophrenia, current treatment strategies largely fail to ameliorate these impairments. To develop more efficient treatment strategies in patients with schizophrenia, a better understanding of the pathogenesis of these cognitive deficits is needed. Accumulating evidence indicates that genetic risk of schizophrenia may contribute to cognitive dysfunction...
July 26, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28743610/epidemiology-and-comorbidities-of-patients-with-chronic-urticaria-in-taiwan%C3%A2-a-nationwide-population-based-study
#2
Chia-Yu Chu, Yung-Tsu Cho, Jhih-Hua Jiang, Eve I-Chun Lin, Chao-Hsiun Tang
BACKGROUND: Comprehensive data regarding the epidemiology of chronic urticaria (CU) in general populations are scant. OBJECTIVES: To investigate the prevalence, incidence, and comorbidities of CU in general population. METHODS: The data were sourced from the National Health Insurance Research Database (NHIRD) for 2009-2012. Patients who had a primary/secondary ICD-9-CM diagnosis code of 708.1, 708.8, or 708.9 during the year with at least two outpatient visits and an antihistamine prescription, were identified as the cases of CU for each year...
July 15, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28742411/is-major-depression-linked-to-alcohol-impaired-driving
#3
Ye Z Pogue, Jahn K Hakes, Frank A Sloan
BACKGROUND: Alcohol-impaired driving causes a substantial proportion of motor vehicle accidents. Depression is a prevalent psychiatric disorder among drinker-drivers. Few previous studies have investigated the relationship between major depression and alcohol-impaired driving. OBJECTIVES: We investigated whether depression has a positive relationship with the probability of alcohol-impaired driving after controlling for the co-occurrence of binge drinking and alcohol dependence...
July 25, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28734019/association-between-androgen-deprivation-therapy-and-anxiety-among-78-000-patients-with-localized-prostate-cancer
#4
Kathryn T Dinh, David D Yang, Kevin T Nead, Gally Reznor, Quoc-Dien Trinh, Paul L Nguyen
OBJECTIVES: To examine whether any androgen deprivation therapy use or longer duration is associated with an increased risk of anxiety in patients with prostate cancer. METHODS: We identified 78 552 men aged ≥66 years with stage I-III prostate cancer using the Surveillance, Epidemiology, and End Results-Medicare linked database from 1992 to 2006, excluding patients with psychiatric diagnoses within the year prior or 6 months after prostate cancer diagnosis. Multivariable Cox regression was used to examine the association between pharmacological androgen deprivation therapy and diagnosis of anxiety...
July 22, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28729345/recent-advances-in-understanding-and-managing-body-dysmorphic-disorder
#5
REVIEW
Georgina Krebs, Lorena Fernández de la Cruz, David Mataix-Cols
Body dysmorphic disorder (BDD) is a relatively common and disabling psychiatric disorder characterised by excessive and persistent preoccupation with perceived defects or flaws in one's appearance, which are unnoticeable to others, and associated repetitive behaviours (eg, mirror checking). The disorder generally starts in adolescence, but often goes unnoticed and is severely underdiagnosed. Left untreated, BDD typically persists and causes marked functional impairment in multiple domains. This clinical review considers recent advances in the epidemiology and classification of BDD, including its reclassification in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders under the new 'Obsessive-Compulsive and Related Disorders' chapter...
July 20, 2017: Evidence-based Mental Health
https://www.readbyqxmd.com/read/28724431/biological-embedding-of-childhood-adversity-from-physiological-mechanisms-to-clinical-implications
#6
REVIEW
Anne E Berens, Sarah K G Jensen, Charles A Nelson
BACKGROUND: Adverse psychosocial exposures in early life, namely experiences such as child maltreatment, caregiver stress or depression, and domestic or community violence, have been associated in epidemiological studies with increased lifetime risk of adverse outcomes, including diabetes, heart disease, cancers, and psychiatric illnesses. Additional work has shed light on the potential molecular mechanisms by which early adversity becomes "biologically embedded" in altered physiology across body systems...
July 20, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28714421/the-prevalence-age-of-onset-and-the-correlates-of-dsm-iv-psychiatric-disorders-in-the-tianjin-mental-health-survey-tjmhs
#7
H Yin, G Xu, H Tian, G Yang, K J Wardenaar, R A Schoevers
BACKGROUND: To effectively shape mental healthcare policy in modern-day China, up-to-date epidemiological data on mental disorders is needed. The objective was to estimate the prevalence, age-of-onset (AOO) and sociodemographic correlates of mental disorders in a representative household sample of the general population (age ⩾ 18) in the Tianjin Municipality in China. METHODS: Data came from the Tianjin Mental health Survey (TJMHS), which was conducted between July 2011 and March 2012 using a two-phase design...
July 17, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28711797/symptom-severity-and-disability-in-psychiatric-disorders-the-u-s-collaborative-psychiatric-epidemiology-survey
#8
R García-Velázquez, M Jokela, T H Rosenström
BACKGROUND: While most psychiatric diagnoses are based on simple counts of symptoms, some symptoms may be sign of a more severe mental syndrome than others. This calls for validated estimates of the relative severity specific symptoms imply within a disorder. We focused on four diagnostic disorders: Manic Episode (ME), Major Depressive Episode (MDE), Post-traumatic Stress Disorder (PTSD) and Generalized Anxiety Disorder (GAD). Symptom-specific severity parameters were estimated, and validated by examining their association with levels of self-reported disability in daily activities over and above the number of symptoms...
November 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28709821/the-mandarin-version-of-the-kiddie-schedule-for-affective-disorders-and-schizophrenia-epidemiological-version-for-dsm-5-a-psychometric-study
#9
Yi-Lung Chen, Lih-Jong Shen, Susan Shur-Fen Gau
BACKGROUND/PURPOSE: Changes of diagnostic coverage and criteria for psychiatric disorders in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) published in 2013 cause a need for updating the Kiddie-Schedule for Affective Disorders and Schizophrenia-Epidemiological version (K-SADS-E). This study examined the preliminary psychometric properties, including inter-rater reliability, and convergent and divergent validity of the modified K-SADS-E for DSM-5...
July 11, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28697570/adherence-to-clinical-practice-guidelines-during-dementia-work-up-in-a-real-world-setting-a-study-from-the-registry-of-dementias-of-girona
#10
Oriol Turró-Garriga, Laia Calvó-Perxas, Joan Vilalta-Franch, Marta Hernández-Ferrándiz, Margarita Flaqué, Marta Linares, Marta Cullell, Jordi Gich, Isabel Casas, Héctor Perkal, Josep Garre-Olmo
BACKGROUND: There are several position statements and clinical practice guidelines (CPG) for diagnosing dementia. OBJECTIVE: Our aims were to evaluate the adherence to CPG among specialists in the 7 memory clinics included in the Registry of Dementias of Girona (ReDeGi), and to compare the results between 2007-2011 and 2012-2015. We also determined the time and number of visits required to achieve a diagnosis, the supplementary tests ordered, and the drugs prescribed according to dementia subtypes...
July 4, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28692653/social-exclusion-and-psychopathology-in-an-online-cohort-of-moroccan-dutch-migrants-results-of-the-medina-study
#11
Madelien H van de Beek, Lian van der Krieke, Robert A Schoevers, Wim Veling
INTRODUCTION: Migration is seen as a risk factor for developing psychiatric symptoms and experiencing social exclusion. In the Netherlands, the Moroccan-Dutch population is the second largest migrant group. 70% of all young Moroccan-Dutch people meet each other in the online community www.marokko.nl. Within this community, we investigated the association between experiences of social exclusion and self-reported depressive symptoms and psychotic experiences. MATERIALS AND METHODS: Participants were recruited via the website www...
2017: PloS One
https://www.readbyqxmd.com/read/28686988/prevalence-correlates-comorbidity-and-treatment-of-electronic-nicotine-delivery-system-use-in-the-united-states
#12
S Patricia Chou, Tulshi D Saha, Haitao Zhang, W June Ruan, Boji Huang, Bridget F Grant, Carlos Blanco, Wilson Compton
INTRODUCTION: This study presents nationally representative data on the prevalence, correlates, psychiatric comorbidity and treatment (including pharmacological and nonpharmacological) among electronic nicotine delivery system (ENDS) users. METHODS: Face-to-face interviews in the National Epidemiologic Survey on Alcohol and Related Conditions-III. RESULTS: Prevalences of 12-month and lifetime ENDS use were 3.8% (SE=0.14) and 5.4% (SE=0.17)...
June 24, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28686572/adolescent-suicide-as-a-global-public-health-issue
#13
Zebib K Abraham, Leo Sher
Youth suicide is a major global mental health problem. This review looks at the epidemiology, risk and protective factors associated with youth suicide, and global strategies to address this important issue. To better understand factors contributing to youth suicide, global gender differences in suicide were examined. Global rates of suicide amongst young men are higher than young women. However, there are anomalously higher rates of female youth suicide in India and China, and possible causes of this are examined further...
July 7, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28686353/national-scale-precision-medicine-for-psychiatric-disorders-in-sweden
#14
REVIEW
Sarah E Bergen, Patrick F Sullivan
Since psychiatric disorders have genetic architectures dominated by common variants of small effects, successful elucidation in psychiatric genetics necessitates large sample sizes. Collaboration and unconventional ascertainment methods are required to fulfill this need. Electronic health records have been increasingly seen as holding great potential for research, although they often pose substantial technical, legal and ethical challenges. Universal health care and national-scale registers with comprehensive medical, developmental, demographic, and geographic information make the Nordic countries ideal for psychiatric genetic epidemiology...
July 7, 2017: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/28682231/g%C3%A3-n%C3%A3-tique-et-%C3%A3-pig%C3%A3-n%C3%A3-tique-des-troubles-des-conduites-alimentaires
#15
Nicolas Ramoz, Julia Clarke, Philip Gorwood
Eating disorders (EDs) are complex and multifactorial psychiatric illnesses that induce significant and sustained pathological disruption of food intake. The Diagnostic and Statistical Manual of Mental Illnesses (DSM-5) describes the clinical criteria of major disorders including anorexia nervosa (AN), bulimia nervosa (BN) and binge eating disorder (BED). The neurobiological basis of food intake is well characterized. Epidemiological studies reported a heritability about 70% in AN and 60% in BN, suggesting that genetic factors are involved in the vulnerability to EDs...
2017: Biologie Aujourd'hui
https://www.readbyqxmd.com/read/28681667/psychiatric-comorbidities-in-epilepsy
#16
Colin B Josephson, Nathalie Jetté
Psychiatric comorbidities, including mood, anxiety, and psychotic disorders, are common in epilepsy, often occurring at rates 2-3-fold or higher than in the general population without epilepsy. This article discusses the epidemiology of psychiatric disorders in epilepsy, hypotheses regarding the pathogenesis of these comorbidities, and treatment implications. More specifically, it addresses: (1) How common are major depressive disorder, anxiety disorders, and psychotic disorders in epilepsy? (2) How does one screen for these psychiatric disorders in persons with epilepsy? (3) Why do psychiatric conditions occur in epilepsy? (4) Is the treatment of psychiatric comorbidity in epilepsy associated with seizures? The important topic of suicide and suicidal ideation in epilepsy, risk factors for their occurrence, and how to screen for these co-existent conditions is also discussed...
July 6, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28681625/coeliac-disease-and-psychiatric-comorbidity-epidemiology-pathophysiological-mechanisms-quality-of-life-and-gluten-free-diet-effects
#17
Giulia Cossu, Mauro Giovanni Carta, Federico Contu, Quirico Mela, Luigi Demelia, Luca Elli, Bernardo Dell'Osso
Coeliac Disease (CD) is an autoimmune disease in which an environmental factor, gluten, triggers a pathological reaction. It results in intra- and entra-intestinal manifestations of disease, including, most frequently, diarrhoea, weight loss, and anaemia. CD occurs in ∼1% of the western population, being one of the most common autoimmune lifelong disorders, and may present with a variety of psychiatric comorbidities. Psychiatric comorbidity in CD often complicates the diagnosis, reduces the quality-of-life, and worsens the prognosis of affected patients...
July 6, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28677172/neurological-and-psychiatric-associations-in-bullous-pemphigoid-more-than-skin-deep
#18
REVIEW
Anna-Kaisa Försti, Laura Huilaja, Enno Schmidt, Kaisa Tasanen
In elderly patients, bullous pemphigoid (BP) is associated with several comorbidities; the strongest association occurs between BP and neurological diseases. Different types of dementia, Parkinson's disease, cerebrovascular disorders and epilepsy all have a significant association with BP but patients with multiple sclerosis have the highest risk of BP. An existing neurological disorder appears to increase the risk for subsequent BP, but an increased risk for developing some neurological diseases has also been reported following BP diagnosis...
July 4, 2017: Experimental Dermatology
https://www.readbyqxmd.com/read/28670127/suicide-and-lyme-and-associated-diseases
#19
Robert C Bransfield
PURPOSE: The aim of this paper is to investigate the association between suicide and Lyme and associated diseases (LAD). No journal article has previously performed a comprehensive assessment of this subject. INTRODUCTION: Multiple case reports and other references demonstrate a causal association between suicidal risk and LAD. Suicide risk is greater in outdoor workers and veterans, both with greater LAD exposure. Multiple studies demonstrate many infections and the associated proinflammatory cytokines, inflammatory-mediated metabolic changes, and quinolinic acid and glutamate changes alter neural circuits which increase suicidality...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28666429/common-adult-psychiatric-disorders-in-swedish-primary-care-where-most-mental-health-patients-are-treated
#20
Jan Sundquist, Henrik Ohlsson, Kristina Sundquist, Kenneth S Kendler
BACKGROUND: The overall aim of this study is to present descriptive data regarding the treated prevalence of nine common psychiatric and substance use disorders in the first Primary Care Registry (PCR) in Sweden: Major Depression (MD), Anxiety Disorders (AD), Obsessive-Compulsive Disorder (OCD), Adjustment Disorder (AdjD), Eating Disorders (ED), Personality Disorder (PD), Attention Deficit Hyperactivity Disorder (ADHD), Alcohol Use Disorder (AUD) and Drug Abuse (DA). METHOD: We selected 5,397,675 individuals aged ≥18...
June 30, 2017: BMC Psychiatry
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