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Psychiatric Epidemiology

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https://www.readbyqxmd.com/read/28099215/prevalence-and-severity-of-depression-and-anxiety-in-patients-with-systemic-sclerosis-an-epidemiologic-survey-and-investigation-of-clinical-correlates
#1
Seyedeh Tahereh Faezi, Pedram Paragomi, Ashraf Shahali, Maryam Akhlaghkhah, Mahmood Akbarian, Maassoomeh Akhlaghi, Masoumeh Kheirandish, Farhad Gharibdoost
BACKGROUND: Systemic sclerosis (SSc) is a chronic multisystem connective tissue disorder with detrimental impact on quality of life. Patients with SSc face emotional distress and frequently meet criteria for a psychiatric disorder. However, the pattern of psychiatric manifestations may vary according to socioethnic background. OBJECTIVES: We investigated the prevalence of depressive and anxiety symptoms and examined their association with sociodemographic and clinical factors in Iranian SSc patients...
January 18, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28098394/use-of-asian-samples-in-genetic-research-of-alcohol-use-disorders-genetic-variation-of-alcohol-metabolizing-enzymes-and-the-effects-of-acetaldehyde
#2
Sachio Matsushita, Susumu Higuchi
BACKGROUND AND OBJECTIVES: Epidemiological studies consistently find that Asian populations report lower rates of alcohol use disorders (AUD) compared with other racial groups. These differences result from a variety of biological, genetic, and environmental influences, some of which are related to the metabolism of alcohol. We will review several studies of these metabolic factors, including several alcohol clamping studies conducted in our laboratory, that provide further insight into the role of the alcohol metabolizing genes and drinking behavior among Japanese drinkers...
January 18, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28069623/epidemiological-survey-of-the-feasibility-of-broadband-ultrasound-attenuation-measured-using-calcaneal-quantitative-ultrasound-to-predict-the-incidence-of-falls-in-the-middle-aged-and-elderly
#3
Ling-Chun Ou, Yin-Fan Chang, Chin-Sung Chang, Ching-Ju Chiu, Ting-Hsing Chao, Zih-Jie Sun, Ruey-Mo Lin, Chih-Hsing Wu
OBJECTIVES: We investigated whether calcaneal quantitative ultrasound (QUS-C) is a feasible tool for predicting the incidence of falls. DESIGN: Prospective epidemiological cohort study. SETTING: Community-dwelling people sampled in central western Taiwan. PARTICIPANTS: A cohort of community-dwelling people who were ≥40 years old (men: 524; women: 676) in 2009-2010. Follow-up questionnaires were completed by 186 men and 257 women in 2012...
January 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28067758/pain-interference-psychopathology-and-general-medical-conditions-among-black-and-white-adults-in-the-us-general-population
#4
Declan T Barry, Corey Pilver Glenn, Rani A Hoff, Marc N Potenza
OBJECTIVES: To assess how race might moderate relationships between pain interference and psychopathology, and general medical conditions among a nationally representative sample of black and white adults. METHODS: Chi-square tests and multivariable logistic regression analyses were performed on data from the National Epidemiologic Survey on Alcohol and Related Conditions on 32,474 adult respondents (25% black, 75% white), who were categorized according to 1 of 3 levels of pain interference (ie, no/low, moderate, or severe)...
January 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28062923/cardiovascular-disease-and-psychiatric-disorders-among-latinos-in-the-united-states
#5
Leopoldo J Cabassa, Roberto Lewis-Fernández, Shuai Wang, Carlos Blanco
PURPOSE: Cardiovascular disease (CVD) is the leading cause of death among Latinos and disproportionately impacts people with psychiatric disorders. The aim of this study was to examine the relationships between CVD and psychiatric disorders among different Latino subgroups using a nationally representative sample. METHODS: Latinos participants (N = 6359) were drawn from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions. A structured diagnostic interview was used to determine psychiatric diagnoses for any past-year mood, anxiety, and substance use disorders...
January 6, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28044063/molecular-mechanisms-underlying-noncoding-risk-variations-in-psychiatric-genetic-studies
#6
REVIEW
X Xiao, H Chang, M Li
Recent large-scale genetic approaches such as genome-wide association studies have allowed the identification of common genetic variations that contribute to risk architectures of psychiatric disorders. However, most of these susceptibility variants are located in noncoding genomic regions that usually span multiple genes. As a result, pinpointing the precise variant(s) and biological mechanisms accounting for the risk remains challenging. By reviewing recent progresses in genetics, functional genomics and neurobiology of psychiatric disorders, as well as gene expression analyses of brain tissues, here we propose a roadmap to characterize the roles of noncoding risk loci in the pathogenesis of psychiatric illnesses (that is, identifying the underlying molecular mechanisms explaining the genetic risk conferred by those genomic loci, and recognizing putative functional causative variants)...
January 3, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28032331/intergenerational-transmission-of-post-traumatic-stress-disorder-in-australian-vietnam-veterans-families
#7
B I O'Toole, M J Burton, A Rothwell, S Outram, M Dadds, S V Catts
OBJECTIVE: To assess the association between parental post-traumatic stress disorder (PTSD) and offspring PTSD and its specificity for other disorders in a non-clinical epidemiological cohort of Australian Vietnam veterans, their partners and their sons and daughters. METHOD: Veterans were interviewed twice, in 1992-1994 and 2005-2006; partners were interviewed in 2006-2007, and their offspring in 2012-2014. A total of 125 sons and 168 daughters were interviewed from 197 families, 137 of which also included partners who were the mothers of the children...
December 28, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28029516/marriage-and-outcomes-of-people-with-schizophrenia-in-rural-china-14-year-follow-up-study
#8
Mao-Sheng Ran, Yin-Ling Irene Wong, Shu-Yan Yang, Petula S Y Ho, Wen-Jun Mao, Jie Li, Cecilia Lai-Wan Chan
The influence of marriage on the long-term outcomes of schizophrenia is largely unknown. This study was to examine the impact of marriage on the 14-year outcomes and identify the correlates of marriage among persons with schizophrenia in rural community. All study participants with schizophrenia (n=510) were identified in 1994 in an epidemiological investigation of 123,572 people aged 15years and older and followed up in 2004 and 2008 in Xinjin County, Chengdu, China. The Patients Follow-up Schedule (PFS) was used in 2004 and 2008...
October 28, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/28028523/anxiety-depression-and-distress-among-irritable-bowel-syndrome-and-their-subtypes-an-epidemiological-population-based-study
#9
Hamidreza Roohafza, Ehsan Zare Bidaki, Ammar Hasanzadeh-Keshteli, Hamed Daghaghzade, Hamid Afshar, Peyman Adibi
BACKGROUND: Psychiatric disorders are common in irritable bowel syndrome (IBS). We conducted this study to investigate the relationship of IBS and their subtypes with some of psychological factors. MATERIALS AND METHODS: A cross-sectional study was performed among 4763 staff of Isfahan University of Medical Sciences in 2011. Modified ROME III questionnaire and Talley Bowel Disease Questionnaire were used to evaluate IBS symptoms. Hospital Anxiety and Depression Scale and 12-item General Health Questionnaire were utilized to assess anxiety, depression and psychological distress...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28002544/the-genetic-architecture-of-major-depressive-disorder-in-han-chinese-women
#10
Roseann E Peterson, Na Cai, Tim B Bigdeli, Yihan Li, Mark Reimers, Anna Nikulova, Bradley T Webb, Silviu-Alin Bacanu, Brien P Riley, Jonathan Flint, Kenneth S Kendler
Importance: Despite the moderate, well-demonstrated heritability of major depressive disorder (MDD), there has been limited success in identifying replicable genetic risk loci, suggesting a complex genetic architecture. Research is needed to quantify the relative contribution of classes of genetic variation across the genome to inform future genetic studies of MDD. Objectives: To apply aggregate genetic risk methods to clarify the genetic architecture of MDD by estimating and partitioning heritability by chromosome, minor allele frequency, and functional annotations and to test for enrichment of rare deleterious variants...
December 21, 2016: JAMA Psychiatry
https://www.readbyqxmd.com/read/27998373/sleep-quality-in-an-adult-american-indian-community-sample
#11
Cindy L Ehlers, Derek N Wills, Philip Lau, David A Gilder
STUDY OBJECTIVES: Epidemiological studies have found that insufficient sleep (< 7 h/night) is more common among American Indians/Alaska Natives (AI/AN). In this study we sought to identify specific demographic, clinical, and cultural factors that may be associated with reduced sleep quality in an American Indian community sample. METHODS: Information on demography along with personal medical, psychiatric, and drinking history was obtained using the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA)...
December 16, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27993226/maternal-depressive-symptoms-during-and-after-pregnancy-and-psychiatric-problems-in-children
#12
Marius Lahti, Katri Savolainen, Soile Tuovinen, Anu-Katriina Pesonen, Jari Lahti, Kati Heinonen, Esa Hämäläinen, Hannele Laivuori, Pia M Villa, Rebecca M Reynolds, Eero Kajantie, Katri Räikkönen
OBJECTIVE: Maternal depressive symptoms during pregnancy are associated with increased risk of psychiatric problems in children. A more precise understanding of the timing of the symptoms during pregnancy and their independence of other prenatal and postnatal factors in predicting child psychopathology risk is needed. We examined whether maternal depressive symptoms during pregnancy predict child psychiatric problems, whether these associations are trimester- or gestational-week-specific and/or independent of pregnancy disorders, and whether maternal depressive symptoms after pregnancy mediate or add to the prenatal effects...
January 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/27984559/psychiatric-symptoms-in-patients-receiving-dolutegravir
#13
Anna Fettiplace, Chris Stainsby, Alan Winston, Naomi Givens, Sarah Puccini, Vani Vannappagari, Ricky Hsu, Jennifer Fusco, Romina Quercia, Michael Aboud, Lloyd Curtis
INTRODUCTION: Psychiatric symptoms are reported to occur frequently in people living with HIV and may be associated with specific antiretrovirals. We analysed psychiatric symptoms observed with dolutegravir and other frequently prescribed anchor drugs. METHODS: Selected psychiatric symptoms (insomnia, anxiety, depression, and suicidality) occurring in HIV-positive patients during dolutegravir treatment across 5 randomized clinical trials (3 double-blind), in the Observational Pharmaco-Epidemiology Research & Analysis (OPERA®) cohort, and among cases spontaneously reported to ViiV Healthcare were analysed...
December 7, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27977232/interpersonal-callousness-and-co-occurring-anxiety-developmental-validity-of-an-adolescent-taxonomy
#14
Alan J Meehan, Barbara Maughan, Charlotte A M Cecil, Edward D Barker
Growing evidence suggests heterogeneity within interpersonal-callous (IC) youth based on co-occurring anxiety. The developmental validity of this proposed taxonomy remains unclear however, as most previous research is cross-sectional and/or limited to adolescence. We aimed to identify low-anxiety (IC/ANX-) and high-anxiety (IC/ANX+) IC variants, and compare these groups on (a) early risk exposures, (b) psychiatric symptoms from midchildhood to early adolescence, and (c) school-based functioning. Using the Avon Longitudinal Study of Parents and Children (ALSPAC), a prospective epidemiological birth cohort, model-based cluster analysis was performed on children with complete age-13 IC and anxiety scores (n = 6,791)...
December 15, 2016: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/27940258/evolution-of-structural-abnormalities-in-the-rat-brain-following-in-utero-exposure-to-maternal-immune-activation-a-longitudinal-in-vivo-mri-study
#15
William R Crum, Stephen J Sawiak, Winfred Chege, Jonathan D Cooper, Steven C R Williams, Anthony C Vernon
Genetic and environmental risk factors for psychiatric disorders are suggested to disrupt the trajectory of brain maturation during adolescence, leading to the development of psychopathology in adulthood. Rodent models are powerful tools to dissect the specific effects of such risk factors on brain maturational profiles, particularly when combined with Magnetic Resonance Imaging (MRI; clinically comparable technology). We therefore investigated the effect of maternal immune activation (MIA), an epidemiological risk factor for adult-onset psychiatric disorders, on rat brain maturation using atlas and tensor-based morphometry analysis of longitudinal in vivo MR images...
December 9, 2016: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/27940200/polyunsaturated-fatty-acids-and-suicide-risk-in-mood-disorders-a-systematic-review
#16
REVIEW
Maurizio Pompili, Lucia Longo, Giovanni Dominici, Gianluca Serafini, Dorian A Lamis, Jerome Sarris, Mario Amore, Paolo Girardi
Deficiency of omega-3 polyunsaturated fatty acids (PUFAs) and an alteration between the ratio of omega-3 and omega-6 PUFAs may contribute to the pathogenesis of bipolar disorder and unipolar depression. Recent epidemiological studies have also demonstrated an association between the depletion of PUFAs and suicide. Our aim was to investigate the relationship between PUFAs and suicide; assess whether the depletion of PUFAs may be considered a risk factor for suicidal behavior; in addition to detailing the potential use of PUFAs in clinical practice...
March 6, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/27933010/differential-recall-bias-intermediate-confounding-and-mediation-analysis-in-life-course-epidemiology-an-analytic-framework-with-empirical-example
#17
Mashhood A Sheikh, Birgit Abelsen, Jan Abel Olsen
The mechanisms by which childhood socioeconomic status (CSES) affects adult mental health, general health, and well-being are not clear. Moreover, the analytical assumptions employed when assessing mediation in social and psychiatric epidemiology are rarely explained. The aim of this paper was to explain the intermediate confounding assumption, and to quantify differential recall bias in the association between CSES, childhood abuse, and mental health (SCL-10), general health (EQ-5D), and subjective well-being (SWLS)...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27931895/self-stigma-in-depressive-patients-association-of-cognitive-schemata-depression-and-self-esteem
#18
Sakie Shimotsu, Naoshi Horikawa
Many empirical studies have indicated that various psychosocial and psychiatric variables are correlated with levels of self-stigma. Treatment methods for reducing self-stigma have been investigated in recent years, especially those examining the relationship between negative cognitive schemata and self-stigma. This study examined the relationship of self-stigma with cognitive schemata, depression, and self-esteem in depressive patients. Furthermore, structural equation modeling (SEM) was conducted to evaluate three hypothetical models...
December 2016: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/27922603/digital-footprints-facilitating-large-scale-environmental-psychiatric-research-in-naturalistic-settings-through-data-from-everyday-technologies
#19
N Bidargaddi, P Musiat, V-P Makinen, M Ermes, G Schrader, J Licinio
Digital footprints, the automatically accumulated by-products of our technology-saturated lives, offer an exciting opportunity for psychiatric research. The commercial sector has already embraced the electronic trails of customers as an enabling tool for guiding consumer behaviour, and analogous efforts are ongoing to monitor and improve the mental health of psychiatric patients. The untargeted collection of digital footprints that may or may not be health orientated comprises a large untapped information resource for epidemiological scale research into psychiatric disorders...
December 6, 2016: Molecular Psychiatry
https://www.readbyqxmd.com/read/27917803/relationship-between-internet-addiction-and-alexithymia-among-university-students
#20
Seher Baysan-Arslan, Sevsen Cebeci, Mehmet Kaya, Metin Canbal
PURPOSE: Epidemiological studies concerning internet addiction found that 50% of internet addicts also have other kinds of psychiatric disorders. This study aims to examine the relationship between alexithymia and internet addiction levels among Turgut Özal University students in Ankara, Turkey. METHOD: University students (1,107 students; 452 students from 12 associate degree programs and 655 students from 10 undergraduate programs) participated in the study. The researchers used the personal information form, the Toronto Alexithymia Scale and the Internet Addiction Scale...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
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