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https://read.qxmd.com/read/37625434/seasonal-vaccination-with-rts-s-as01-e-vaccine-with-or-without-seasonal-malaria-chemoprevention-in-children-up-to-the-age-of-5-years-in-burkina-faso-and-mali-a-double-blind-randomised-controlled-phase-3-trial
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JOURNAL ARTICLE
Alassane Dicko, Jean-Bosco Ouedraogo, Issaka Zongo, Issaka Sagara, Matthew Cairns, Rakiswendé Serge Yerbanga, Djibrilla Issiaka, Charles Zoungrana, Youssoufa Sidibe, Amadou Tapily, Frédéric Nikièma, Frédéric Sompougdou, Koualy Sanogo, Mahamadou Kaya, Hama Yalcouye, Oumar Mohamed Dicko, Modibo Diarra, Kalifa Diarra, Ismaila Thera, Alassane Haro, Abdoul Aziz Sienou, Seydou Traore, Almahamoudou Mahamar, Amagana Dolo, Irene Kuepfer, Paul Snell, Jane Grant, Jayne Webster, Paul Milligan, Cynthia Lee, Christian Ockenhouse, Opokua Ofori-Anyinam, Halidou Tinto, Abdoulaye Djimde, Daniel Chandramohan, Brian Greenwood
BACKGROUND: Seasonal vaccination with the RTS,S/AS01E vaccine combined with seasonal malaria chemoprevention (SMC) prevented malaria in young children more effectively than either intervention given alone over a 3 year period. The objective of this study was to establish whether the added protection provided by the combination could be sustained for a further 2 years. METHODS: This was a double-blind, individually randomised, controlled, non-inferiority and superiority, phase 3 trial done at two sites: the Bougouni district and neighbouring areas in Mali and Houndé district, Burkina Faso...
August 22, 2023: Lancet Infectious Diseases
https://read.qxmd.com/read/34414835/development-of-a-chronic-canine-ovariohysterectomy-model-to-evaluate-vaginal-cuff-healing-using-two-closure-systems
#2
JOURNAL ARTICLE
David Wiseman, Josa A Hanzlik, James A Richardson, John M Shelton, Bret M Evers, Michael P Diamond, Ryan Brown, Dan C Mazzucco
Background and Purpose. This study established a suitable animal model of ovariohysterectomy; characterized the course and pattern of vaginal healing after ovariohysterectomy; and compared healing obtained after closure of the vaginal cuff with a novel cuff-closure device (Zip-stitch® clips) and VICRYL® sutures. Research Design and Study Sample. This prospective, randomized, controlled, blinded animal study was conducted in 27 mongrel hounds according to an IACUC-approved protocol. Each animal underwent ovariohysterectomy followed by vaginal cuff closure with Zip-stitch or VICRYL...
August 20, 2021: Surgical Innovation
https://read.qxmd.com/read/6738511/canine-urolithiasis-diagnosis-and-treatment
#3
JOURNAL ARTICLE
L D Lewis, M L Morris
Over 97% of all uroliths in males less than a year of age and in females are phosphate, excluding males with portosystemic shunts and male Dalmatians . Uroliths in male Dalmatians usually are composed of urate. Uroliths associated with Staphylococcus aureus urinary tract infection are phosphate. About 60% of uroliths in adult male Basset Hounds , Bulldogs , Chihuahuas , Irish Terriers and Yorkshire Terriers are cystine. In males of other breeds, as high as 60% of uroliths are phosphate. Feeding a calculolytic diet (s/d: Hill's) results in phosphate urolith dissolution in 2-20 weeks...
May 1984: Modern Veterinary Practice
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