Philip M Carlucci, Katherine Preisinger, Kristina K Deonaraine, Devyn Zaminski, Maria Dall'Era, Heather T Gold, Kenneth Kalunian, Andrea Fava, H Michael Belmont, Ming Wu, Chaim Putterman, Jennifer Anolik, Jennifer L Barnas, Richard Furie, Betty Diamond, Anne Davidson, David Wofsy, Diane Kamen, Judith A James, Joel M Guthridge, William Apruzzese, Deepak Rao, Michael H Weisman, Peter M Izmirly, Jill Buyon, Michelle Petri
OBJECTIVE: Lupus nephritis (LN) can occur as an isolated component of disease activity or be accompanied by diverse extrarenal manifestations. Whether isolated renal disease is sufficient to decrease health related quality of life (HRQOL) remains unknown. This study compared Patient-Reported Outcomes Measurement Information System 29-Item (PROMIS-29) scores in LN patients with isolated renal disease to those with extrarenal symptoms to evaluate the burden of LN on HRQOL and inform future LN clinical trials incorporating HRQOL outcomes...
March 26, 2024: Rheumatology