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https://www.readbyqxmd.com/read/29906486/pathophysiological-consequences-of-isoform-specific-ip-3-receptor-mutations
#1
REVIEW
Martijn Kerkhofs, Bruno Seitaj, Hristina Ivanova, Giovanni Monaco, Geert Bultynck, Jan B Parys
Ca2+ signaling governs a diverse range of cellular processes and, as such, is subject to tight regulation. A main component of the complex intracellular Ca2+ -signaling network is the inositol 1,4,5-trisphosphate (IP3 ) receptor (IP3 R), a tetrameric channel that mediates Ca2+ release from the endoplasmic reticulum (ER) in response to IP3 . IP3 R function is controlled by a myriad of factors, such as Ca2+ , ATP, kinases and phosphatases and a plethora of accessory and regulatory proteins. Further complexity in IP3 R-mediated Ca2+ signaling is the result of the existence of three main isoforms (IP3 R1, IP3 R2 and IP3 R3) that display distinct functional characteristics and properties...
June 12, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29906166/search-for-heavy-neutral-leptons-in-events-with-three-charged-leptons-in-proton-proton-collisions-at-sqrt-s-13-tev
#2
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Micheli, P Musella, F Nessi-Tedaldi, F Pandolfi, J Pata, F Pauss, G Perrin, L Perrozzi, M Quittnat, M Reichmann, D A Sanz Becerra, M Schönenberger, L Shchutska, V R Tavolaro, K Theofilatos, M L Vesterbacka Olsson, R Wallny, D H Zhu, T K Aarrestad, C Amsler, D Brzhechko, M F Canelli, A De Cosa, R Del Burgo, S Donato, C Galloni, T Hreus, B Kilminster, I Neutelings, D Pinna, G Rauco, P Robmann, D Salerno, K Schweiger, C Seitz, Y Takahashi, A Zucchetta, V Candelise, Y H Chang, K Y Cheng, T H Doan, Sh Jain, R Khurana, C M Kuo, W Lin, A Pozdnyakov, S S Yu, Arun Kumar, P Chang, Y Chao, K F Chen, P H Chen, F Fiori, W-S Hou, Y Hsiung, Y F Liu, R-S Lu, E Paganis, A Psallidas, A Steen, J F Tsai, B Asavapibhop, K Kovitanggoon, G Singh, N Srimanobhas, M N Bakirci, A Bat, F Boran, S Damarseckin, Z S Demiroglu, C Dozen, E Eskut, S Girgis, G Gokbulut, Y Guler, I Hos, E E Kangal, O Kara, U Kiminsu, M Oglakci, G Onengut, K Ozdemir, S Ozturk, A Polatoz, D Sunar Cerci, U G Tok, S Turkcapar, I S Zorbakir, C Zorbilmez, G Karapinar, K Ocalan, M Yalvac, M Zeyrek, E Gülmez, M Kaya, O Kaya, S Tekten, E A Yetkin, M N Agaras, S Atay, A Cakir, K Cankocak, Y Komurcu, B Grynyov, L Levchuk, F Ball, L Beck, J J Brooke, D Burns, E Clement, D Cussans, O Davignon, H Flacher, J Goldstein, G P Heath, H F Heath, L Kreczko, D M Newbold, S Paramesvaran, T Sakuma, S Seif El Nasr-Storey, D Smith, V J Smith, K W Bell, A Belyaev, C Brew, R M Brown, L Calligaris, D Cieri, D J A Cockerill, J A Coughlan, K Harder, S Harper, J Linacre, E Olaiya, D Petyt, C H Shepherd-Themistocleous, A Thea, I R Tomalin, T Williams, W J Womersley, G Auzinger, R Bainbridge, P Bloch, J Borg, S Breeze, O Buchmuller, A Bundock, S Casasso, D Colling, L Corpe, P Dauncey, G Davies, M Della Negra, R Di Maria, Y Haddad, G Hall, G Iles, T James, M Komm, R Lane, C Laner, L Lyons, A-M Magnan, S Malik, L Mastrolorenzo, T Matsushita, J Nash, A Nikitenko, V Palladino, M Pesaresi, A Richards, A Rose, E Scott, C Seez, A Shtipliyski, T Strebler, S Summers, A Tapper, K Uchida, M Vazquez Acosta, T Virdee, N Wardle, D Winterbottom, J Wright, S C Zenz, J E Cole, P R Hobson, A Khan, P Kyberd, A Morton, I D Reid, L Teodorescu, S Zahid, A Borzou, K Call, J Dittmann, K Hatakeyama, H Liu, N Pastika, C Smith, R Bartek, A Dominguez, A Buccilli, S I Cooper, C Henderson, P Rumerio, C West, D Arcaro, A Avetisyan, T Bose, D Gastler, D Rankin, C Richardson, J Rohlf, L Sulak, D Zou, G Benelli, D Cutts, M Hadley, J Hakala, U Heintz, J M Hogan, K H M Kwok, E Laird, G Landsberg, J Lee, Z Mao, M Narain, J Pazzini, S Piperov, S Sagir, R Syarif, D Yu, R Band, C Brainerd, R Breedon, D Burns, M Calderon De La Barca Sanchez, M Chertok, J Conway, R Conway, P T Cox, R Erbacher, C Flores, G Funk, W Ko, R Lander, C Mclean, M Mulhearn, D Pellett, J Pilot, S Shalhout, M Shi, J Smith, D Stolp, D Taylor, K Tos, M Tripathi, Z Wang, F Zhang, M Bachtis, C Bravo, R Cousins, A Dasgupta, A Florent, J Hauser, M Ignatenko, N Mccoll, S Regnard, D Saltzberg, C Schnaible, V Valuev, E Bouvier, K Burt, R Clare, J Ellison, J W Gary, S M A Ghiasi Shirazi, G Hanson, G Karapostoli, E Kennedy, F Lacroix, O R Long, M Olmedo Negrete, M I Paneva, W Si, L Wang, H Wei, S Wimpenny, B R Yates, J G Branson, S Cittolin, M Derdzinski, R Gerosa, D Gilbert, B Hashemi, A Holzner, D Klein, G Kole, V Krutelyov, J Letts, M Masciovecchio, D Olivito, S Padhi, M Pieri, M Sani, V Sharma, S Simon, M Tadel, A Vartak, S Wasserbaech, J Wood, F Würthwein, A Yagil, G Zevi Della Porta, N Amin, R Bhandari, J Bradmiller-Feld, C Campagnari, M Citron, A Dishaw, V Dutta, M Franco Sevilla, L Gouskos, R Heller, J Incandela, A Ovcharova, H Qu, J Richman, D Stuart, I Suarez, J Yoo, D Anderson, A Bornheim, J Bunn, J M Lawhorn, H B Newman, T Q Nguyen, C Pena, M Spiropulu, J R Vlimant, R Wilkinson, S Xie, Z Zhang, R Y Zhu, M B Andrews, T Ferguson, T Mudholkar, M Paulini, J Russ, M Sun, H Vogel, I Vorobiev, M Weinberg, J P Cumalat, W T Ford, F Jensen, A Johnson, M Krohn, S Leontsinis, E Macdonald, T Mulholland, K Stenson, K A Ulmer, S R Wagner, J Alexander, J Chaves, Y Cheng, J Chu, A Datta, S Dittmer, K Mcdermott, N Mirman, J R Patterson, D Quach, A Rinkevicius, A Ryd, L Skinnari, L Soffi, S M Tan, Z Tao, J Thom, J Tucker, P Wittich, M Zientek, S Abdullin, M Albrow, M Alyari, G Apollinari, A Apresyan, A Apyan, S Banerjee, L A T Bauerdick, A Beretvas, J Berryhill, P C Bhat, G Bolla, K Burkett, J N Butler, A Canepa, G B Cerati, H W K Cheung, F Chlebana, M Cremonesi, J Duarte, V D Elvira, J Freeman, Z Gecse, E Gottschalk, L Gray, D Green, S Grünendahl, O Gutsche, J Hanlon, R M Harris, S Hasegawa, J Hirschauer, Z Hu, B Jayatilaka, S Jindariani, M Johnson, U Joshi, B Klima, B Kreis, S Lammel, D Lincoln, R Lipton, M Liu, T Liu, R Lopes De Sá, J Lykken, K Maeshima, N Magini, J M Marraffino, D Mason, P McBride, P Merkel, S Mrenna, S Nahn, V O'Dell, K Pedro, O Prokofyev, G Rakness, L Ristori, A Savoy-Navarro, B Schneider, E Sexton-Kennedy, A Soha, W J Spalding, L Spiegel, S Stoynev, J Strait, N Strobbe, L Taylor, S Tkaczyk, N V Tran, L Uplegger, E W Vaandering, C Vernieri, M Verzocchi, R Vidal, M Wang, H A Weber, A Whitbeck, W Wu, D Acosta, P Avery, P Bortignon, D Bourilkov, A Brinkerhoff, A Carnes, M Carver, D Curry, R D Field, I K Furic, S V Gleyzer, B M Joshi, J Konigsberg, A Korytov, K Kotov, P Ma, K Matchev, H Mei, G Mitselmakher, K Shi, D Sperka, N Terentyev, L Thomas, J Wang, S Wang, J Yelton, Y R Joshi, S Linn, P Markowitz, J L Rodriguez, A Ackert, T Adams, A Askew, S Hagopian, V Hagopian, K F Johnson, T Kolberg, G Martinez, T Perry, H Prosper, A Saha, A Santra, V Sharma, R Yohay, M M Baarmand, V Bhopatkar, S Colafranceschi, M Hohlmann, D Noonan, T Roy, F Yumiceva, M R Adams, L Apanasevich, D Berry, R R Betts, R Cavanaugh, X Chen, O Evdokimov, C E Gerber, D A Hangal, D J Hofman, K Jung, J Kamin, I D Sandoval Gonzalez, M B Tonjes, N Varelas, H Wang, Z Wu, J Zhang, B Bilki, W Clarida, K Dilsiz, S Durgut, R P Gandrajula, M Haytmyradov, V Khristenko, J-P Merlo, H Mermerkaya, A Mestvirishvili, A Moeller, J Nachtman, H Ogul, Y Onel, F Ozok, A Penzo, C Snyder, E Tiras, J Wetzel, K Yi, B Blumenfeld, A Cocoros, N Eminizer, D Fehling, L Feng, A V Gritsan, P Maksimovic, J Roskes, U Sarica, M Swartz, M Xiao, C You, A Al-Bataineh, P Baringer, A Bean, S Boren, J Bowen, J Castle, S Khalil, A Kropivnitskaya, D Majumder, W Mcbrayer, M Murray, C Rogan, C Royon, S Sanders, E Schmitz, J D Tapia Takaki, Q Wang, A Ivanov, K Kaadze, Y Maravin, A Mohammadi, L K Saini, N Skhirtladze, F Rebassoo, D Wright, A Baden, O Baron, A Belloni, S C Eno, Y Feng, C Ferraioli, N J Hadley, S Jabeen, G Y Jeng, R G Kellogg, J Kunkle, A C Mignerey, F Ricci-Tam, Y H Shin, A Skuja, S C Tonwar, D Abercrombie, B Allen, V Azzolini, R Barbieri, A Baty, G Bauer, R Bi, S Brandt, W Busza, I A Cali, M D'Alfonso, Z Demiragli, G Gomez Ceballos, M Goncharov, P Harris, D Hsu, M Hu, Y Iiyama, G M Innocenti, M Klute, D Kovalskyi, Y-J Lee, A Levin, P D Luckey, B Maier, A C Marini, C Mcginn, C Mironov, S Narayanan, X Niu, C Paus, C Roland, G Roland, J Salfeld-Nebgen, G S F Stephans, K Sumorok, K Tatar, D Velicanu, J Wang, T W Wang, B Wyslouch, S Zhaozhong, A C Benvenuti, R M Chatterjee, A Evans, P Hansen, S Kalafut, Y Kubota, Z Lesko, J Mans, S Nourbakhsh, N Ruckstuhl, R Rusack, J Turkewitz, M A Wadud, J G Acosta, S Oliveros, E Avdeeva, K Bloom, D R Claes, C Fangmeier, F Golf, R Gonzalez Suarez, R Kamalieddin, I Kravchenko, J Monroy, J E Siado, G R Snow, B Stieger, J Dolen, A Godshalk, C Harrington, I Iashvili, D Nguyen, A Parker, S Rappoccio, B Roozbahani, G Alverson, E Barberis, C Freer, A Hortiangtham, A Massironi, D M Morse, T Orimoto, R Teixeira De Lima, T Wamorkar, B Wang, A Wisecarver, D Wood, S Bhattacharya, O Charaf, K A Hahn, N Mucia, N Odell, M H Schmitt, K Sung, M Trovato, M Velasco, R Bucci, N Dev, M Hildreth, K Hurtado Anampa, C Jessop, D J Karmgard, N Kellams, K Lannon, W Li, N Loukas, N Marinelli, F Meng, C Mueller, Y Musienko, M Planer, A Reinsvold, R Ruchti, P Siddireddy, G Smith, S Taroni, M Wayne, A Wightman, M Wolf, A Woodard, J Alimena, L Antonelli, B Bylsma, L S Durkin, S Flowers, B Francis, A Hart, C Hill, W Ji, T Y Ling, W Luo, B L Winer, H W Wulsin, S Cooperstein, O Driga, P Elmer, J Hardenbrook, P Hebda, S Higginbotham, A Kalogeropoulos, D Lange, J Luo, D Marlow, K Mei, I Ojalvo, J Olsen, C Palmer, P Piroué, D Stickland, C Tully, S Malik, S Norberg, A Barker, V E Barnes, S Das, L Gutay, M Jones, A W Jung, A Khatiwada, D H Miller, N Neumeister, C C Peng, H Qiu, J F Schulte, J Sun, F Wang, R Xiao, W Xie, T Cheng, N Parashar, Z Chen, K M Ecklund, S Freed, F J M Geurts, M Guilbaud, M Kilpatrick, W Li, B Michlin, B P Padley, J Roberts, J Rorie, W Shi, Z Tu, J Zabel, A Zhang, A Bodek, P de Barbaro, R Demina, Y T Duh, T Ferbel, M Galanti, A Garcia-Bellido, J Han, O Hindrichs, A Khukhunaishvili, K H Lo, P Tan, M Verzetti, R Ciesielski, K Goulianos, C Mesropian, A Agapitos, J P Chou, Y Gershtein, T A Gómez Espinosa, E Halkiadakis, M Heindl, E Hughes, S Kaplan, R Kunnawalkam Elayavalli, S Kyriacou, A Lath, R Montalvo, K Nash, M Osherson, H Saka, S Salur, S Schnetzer, D Sheffield, S Somalwar, R Stone, S Thomas, P Thomassen, M Walker, A G Delannoy, J Heideman, G Riley, K Rose, S Spanier, K Thapa, O Bouhali, A Castaneda Hernandez, A Celik, M Dalchenko, M De Mattia, A Delgado, S Dildick, R Eusebi, J Gilmore, T Huang, T Kamon, R Mueller, Y Pakhotin, R Patel, A Perloff, L Perniè, D Rathjens, A Safonov, A Tatarinov, N Akchurin, J Damgov, F De Guio, P R Dudero, J Faulkner, E Gurpinar, S Kunori, K Lamichhane, S W Lee, T Mengke, S Muthumuni, T Peltola, S Undleeb, I Volobouev, Z Wang, S Greene, A Gurrola, R Janjam, W Johns, C Maguire, A Melo, H Ni, K Padeken, P Sheldon, S Tuo, J Velkovska, Q Xu, M W Arenton, P Barria, B Cox, R Hirosky, M Joyce, A Ledovskoy, H Li, C Neu, T Sinthuprasith, Y Wang, E Wolfe, F Xia, R Harr, P E Karchin, N Poudyal, J Sturdy, P Thapa, S Zaleski, M Brodski, J Buchanan, C Caillol, D Carlsmith, S Dasu, L Dodd, S Duric, B Gomber, M Grothe, M Herndon, A Hervé, U Hussain, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, V Rekovic, T Ruggles, A Savin, N Smith, W H Smith, N Woods
A search for a heavy neutral lepton N of Majorana nature decaying into a W boson and a charged lepton is performed using the CMS detector at the LHC. The targeted signature consists of three prompt charged leptons in any flavor combination of electrons and muons. The data were collected in proton-proton collisions at a center-of-mass energy of 13 TeV, with an integrated luminosity of 35.9  fb^{-1}. The search is performed in the N mass range between 1 GeV and 1.2 TeV. The data are found to be consistent with the expected standard model background...
June 1, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29904045/classes-of-vitamin-d-status-and-functional-outcome-after-hip-fracture-a-prospective-short-term-study-of-1350-inpatients
#3
Marco Di Monaco, Carlotta Castiglioni, Silvia Di Carlo, Elena La Marmora, Irena Filipovic, Edoardo Milano, Marco A Minetto, Giuseppe Massazza
BACKGROUND: Vitamin D depletion is associated with unfavourable outcomes after hip fracture. However, the classes of vitamin D status currently in use, which are defined according to serum calcifediol levels, have not been validated for their predictive capability of the functional recovery. AIM: To investigate the association between serum calcifediol categorized into 4 classes and the functional recovery after hip fracture. DESIGN: Prospective, short-term observational study...
June 14, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29900796/the-acute-phase-and-hemostatic-response-in-dromedary-camels-camelus-dromedarius
#4
Eva Maria Greunz, Anne K H Krogh, Wouter Pieters, Olga Amann Ruiz, Julia Bohner, Anja Reckendorf, Davide Monaco, Mads Frost Bertelsen
  Acute-phase reactants indicate inflammation and are increasingly used in veterinary medicine to indicate and to monitor progression of disease. Hemostasis and inflammation have interconnected pathophysiologic pathways and influence each other on different levels. This study established observed normal ranges for acute-phase reactants and for coagulation and thromboelastographic (TEG) parameters in 49 dromedary camels ( Camelus dromedarius) and assessed the response to chronic and acute inflammation. Chronically infected animals suffering from lymph abscessation due to Corynebacterium spp...
June 2018: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29900277/high-resolution-crystal-structure-data-of-human-plasma-retinol-binding-protein-rbp4-bound-to-retinol-and-fatty-acids
#5
Massimiliano Perduca, Stefania Nicolis, Barbara Mannucci, Monica Galliano, Hugo L Monaco
Retinol is transported in vertebrate plasma bound to a protein called retinol-binding protein (RBP4) so far believed to be specific for the vitamin. When the protein is saturated with retinol it binds tightly to another plasma protein, transthyretin while when not saturated with retinol it does not bind to TTR (Goodman, 1984). The X-ray structures of human RBP4, holo and devoid of retinol in its binding site are known to resolutions of 2.0 and 2.5 Å (Cowan et al., 1990; Zanotti et al., 1993) [2], [3]. We have shown that RBP4 is not specific for retinol but it is also found in plasma, urine and amniotic fluid bound to fatty acids...
June 2018: Data in Brief
https://www.readbyqxmd.com/read/29895691/caspase-1-inhibition-prevents-glial-inflammasome-activation-and-pyroptosis-in-models-of-multiple-sclerosis
#6
Brienne A McKenzie, Manmeet K Mamik, Leina B Saito, Roobina Boghozian, Maria Chiara Monaco, Eugene O Major, Jian-Qiang Lu, William G Branton, Christopher Power
Multiple sclerosis (MS) is a progressive inflammatory demyelinating disease of the CNS of unknown cause that remains incurable. Inflammasome-associated caspases mediate the maturation and release of the proinflammatory cytokines IL-1β and IL-18 and activate the pore-forming protein gasdermin D (GSDMD). Inflammatory programmed cell death, pyroptosis, was recently shown to be mediated by GSDMD. Here, we report molecular evidence for GSDMD-mediated inflammasome activation and pyroptosis in both myeloid cells (macrophages/microglia) and, unexpectedly, in myelin-forming oligodendrocytes (ODCs) in the CNS of patients with MS and in the MS animal model, experimental autoimmune encephalomyelitis (EAE)...
June 12, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29889096/evaluation-of-dose-calculations-with-inhomogeneity-correction-in-intensity-modulated-radiation-therapy-for-esophagus-cancer
#7
Xiaobo Li, Benhua Xu, Yu Lei, Jianping Zhang, Zhixing Lin, Sicong Li
BACKGROUND: Differences often exist in the dose calculation accuracy caused by using different dose calculation algorithms in non-uniform tissues. OBJECTIVE: To evaluate the accuracy of dose calculation with inhomogeneity correction in intensity-modulated radiation therapy (IMRT) by comparing dose calculated in Monaco with measurements in lung-chest phantom for esophagus cancer treatments. METHODS: Finite size pencil beam (FSPB) and X-ray voxel Monte Carlo (XVMC) were used respectively for IMRT dose recalculations...
June 5, 2018: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/29887417/inflammation-and-atrial-electrical-remodeling-in-patients-with-embolic-strokes-of-undetermined-source
#8
Maurizio Acampa, Pietro Enea Lazzerini, Francesca Guideri, Rossana Tassi, Andrea Lo Monaco, Giuseppe Martini
BACKGROUND: About one third of ischaemic strokes are classified as embolic strokes of undetermined source (ESUS). A silent atrial fibrillation (AF) may play a pathogenic role in these strokes and P wave dispersion (PWD), representing an electrocardiographic (ECG) predictor for paroxysmal AF, thereby a potential marker of covert cardioembolism, was found to be increased in cryptogenic stroke. Furthermore, current evidence links AF to inflammation: inflammatory markers, such as high-sensitive C-reactive protein (hsCRP), have been related to the development and persistence of AF, possibly by promoting atrial remodelling...
May 8, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29886982/multiple-stressors-and-benthic-harmful-algal-blooms-bhabs-potential-effects-of-temperature-rise-and-nutrient-enrichment
#9
A Fricke, A Pey, F Gianni, R Lemée, L Mangialajo
Blooms of Ostreopsis cf. ovata, causing health incidence and mass human intoxications in the Mediterranean, gained special attention over the past decades. To study the potential effects of temperature and nutrient enrichment on this benthic dinoflagellate and other associated microalgae in situ, a multifactorial experiment was set up along a temperature gradient of a heat pump system in Monaco. Microalgae were quantified in experimental units, in the natural biofilm and in the water column. No significant interaction was observed between temperature and nutrients...
June 2018: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/29883369/genomics-of-fibromuscular-dysplasia
#10
REVIEW
Silvia Di Monaco, Adrien Georges, Jean-Philippe Lengelé, Miikka Vikkula, Alexandre Persu
Fibromuscular Dysplasia (FMD) is &ldquo;an idiopathic, segmental, non-atherosclerotic and non-inflammatory disease of the musculature of arterial walls, leading to stenosis of small and medium-sized arteries&rdquo; (Persu, et al; 2014). FMD can lead to hypertension, arterial dissections, subarachnoid haemorrhage, stroke or mesenteric ischemia. The pathophysiology of the disease remains elusive. While familial cases are rare (<5%) in contemporary FMD registries, there is evidence in favour of the existence of multiple genetic factors involved in this vascular disease...
May 21, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29882749/geometric-and-dosimetric-evaluations-of-atlas-based-segmentation-methods-of-mr-images-in-the-head-and-neck-region
#11
Jennifer Petra Kieselmann, Cornelis Philippus Kamerling, Ninon Burgos, Martin J Menten, Clifton David Fuller, Simeon Nill, M Jorge Cardoso, Uwe Oelfke
Owing to its excellent soft-tissue contrast, magnetic resonance (MR) imaging has found an increased application in radiation therapy (RT). Harnessing these properties for treatment planning, automated segmentation methods can alleviate the manual workload burden to the clinical workflow. &#13; &#13; We investigated atlas-based segmentation methods of organs at risk (OARs) in the head and neck (H&N) region: one approach selecting the most similar atlas from a library of segmented images and two multi-atlas approaches...
June 8, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29877718/management-of-a-case-of-unacknowledged-foreign-body-in-the-upper-airway
#12
Federica Gilda D'Agostino, Francesco Monaco, Baldassare Mondello, Dario Familiari, Mario Barone
Tracheobronchial foreign body aspiration occurs rarely in adults and may go unrecognized for a long time, but early detection and immediate retrieval of the foreign body are essential to prevent major morbidity. We describe the case of an adult who unusually aspirated part of his dental prosthesis during an attempted strangulation, which was unacknowledged until 6 months later when he was hospitalized with acute respiratory failure and required an emergency surgical tracheotomy. The foreign body was successfully removed via flexible bronchoscopy...
January 1, 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29864370/search-for-narrow-resonances-in-the-b-tagged-dijet-mass-spectrum-in-proton-proton-collisions-at-sqrt-s-8-tev
#13
A M Sirunyan, A Tumasyan, W Adam, F Ambrogi, E Asilar, T Bergauer, J Brandstetter, E Brondolin, M Dragicevic, J Erö, A Escalante Del Valle, M Flechl, M Friedl, R Frühwirth, V M Ghete, J Grossmann, J Hrubec, M Jeitler, A König, N Krammer, I Krätschmer, D Liko, T Madlener, I Mikulec, E Pree, N Rad, H Rohringer, J Schieck, R Schöfbeck, M Spanring, D Spitzbart, A Taurok, W Waltenberger, J Wittmann, C-E Wulz, M Zarucki, V Chekhovsky, V Mossolov, J Suarez Gonzalez, E A De Wolf, D Di Croce, X Janssen, J Lauwers, M Pieters, M Van De Klundert, H Van Haevermaet, P Van Mechelen, N Van Remortel, S Abu Zeid, F Blekman, J D'Hondt, I De Bruyn, J De Clercq, K Deroover, G Flouris, D Lontkovskyi, S Lowette, I Marchesini, S Moortgat, L Moreels, Q Python, K Skovpen, S Tavernier, W Van Doninck, P Van Mulders, I Van Parijs, D Beghin, B Bilin, H Brun, B Clerbaux, G De Lentdecker, H Delannoy, B Dorney, G Fasanella, L Favart, R Goldouzian, A Grebenyuk, A K Kalsi, T Lenzi, J Luetic, T Seva, E Starling, C Vander Velde, P Vanlaer, D Vannerom, R Yonamine, T Cornelis, D Dobur, A Fagot, M Gul, I Khvastunov, D Poyraz, C Roskas, D Trocino, M Tytgat, W Verbeke, B Vermassen, M Vit, N Zaganidis, H Bakhshiansohi, O Bondu, S Brochet, G Bruno, C Caputo, A Caudron, P David, S De Visscher, C Delaere, M Delcourt, B Francois, A Giammanco, G Krintiras, V Lemaitre, A Magitteri, A Mertens, M Musich, K Piotrzkowski, L Quertenmont, A Saggio, M Vidal Marono, S Wertz, J Zobec, W L Aldá Júnior, F L Alves, G A Alves, L Brito, G Correia Silva, C Hensel, A Moraes, M E Pol, P Rebello Teles, E Belchior Batista Das Chagas, W Carvalho, J Chinellato, E Coelho, E M Da Costa, G G Da Silveira, D De Jesus Damiao, S Fonseca De Souza, H Malbouisson, M Medina Jaime, M Melo De Almeida, C Mora Herrera, L Mundim, H Nogima, L J Sanchez Rosas, A Santoro, A Sznajder, M Thiel, E J Tonelli Manganote, F Torres Da Silva De Araujo, A Vilela Pereira, S Ahuja, C A Bernardes, L Calligaris, T R Fernandez Perez Tomei, E M Gregores, P G Mercadante, S F Novaes, Sandra S Padula, D Romero Abad, J C Ruiz Vargas, A Aleksandrov, R Hadjiiska, P Iaydjiev, A Marinov, M Misheva, M Rodozov, M Shopova, G Sultanov, A Dimitrov, L Litov, B Pavlov, P Petkov, W Fang, X Gao, L Yuan, M Ahmad, J G Bian, G M Chen, H S Chen, M Chen, Y Chen, C H Jiang, D Leggat, H Liao, Z Liu, F Romeo, S M Shaheen, A Spiezia, J Tao, C Wang, Z Wang, E Yazgan, H Zhang, J Zhao, Y Ban, G Chen, J Li, Q Li, S Liu, Y Mao, S J Qian, D Wang, Z Xu, Y Wang, C Avila, A Cabrera, C A Carrillo Montoya, L F Chaparro Sierra, C Florez, C F González Hernández, M A Segura Delgado, B Courbon, N Godinovic, D Lelas, I Puljak, P M Ribeiro Cipriano, T Sculac, Z Antunovic, M Kovac, V Brigljevic, D Ferencek, K Kadija, B Mesic, A Starodumov, T Susa, M W Ather, A Attikis, G Mavromanolakis, J Mousa, C Nicolaou, F Ptochos, P A Razis, H Rykaczewski, M Finger, M Finger, E Carrera Jarrin, Y Assran, S Elgammal, M A Mahmoud, S Bhowmik, R K Dewanjee, M Kadastik, L Perrini, M Raidal, C Veelken, P Eerola, H 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Wang, E Wolfe, F Xia, R Harr, P E Karchin, N Poudyal, J Sturdy, P Thapa, S Zaleski, M Brodski, J Buchanan, C Caillol, D Carlsmith, S Dasu, L Dodd, S Duric, B Gomber, M Grothe, M Herndon, A Hervé, U Hussain, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, V Rekovic, T Ruggles, A Savin, N Smith, W H Smith, N Woods
A search for narrow resonances decaying to bottom quark-antiquark pairs is presented, using a data sample of proton-proton collisions at sqrt[s]=8  TeV corresponding to an integrated luminosity of 19.7  fb^{-1}. The search is extended to masses lower than those reached in typical searches for resonances decaying into jet pairs at the LHC, by taking advantage of triggers that identify jets originating from bottom quarks. No significant excess of events is observed above the background predictions. Limits are set on the product of cross section and branching fraction to bottom quarks for spin 0, 1, and 2 resonances in the mass range of 325-1200 GeV...
May 18, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29864330/measurement-of-prompt-d-0-meson-azimuthal-anisotropy-in-pb-pb-collisions-at-sqrt-s_-nn-5-02-tev
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K A Ulmer, N Akchurin, J Damgov, F De Guio, P R Dudero, J Faulkner, E Gurpinar, S Kunori, K Lamichhane, S W Lee, T Libeiro, T Peltola, S Undleeb, I Volobouev, Z Wang, S Greene, A Gurrola, R Janjam, W Johns, C Maguire, A Melo, H Ni, P Sheldon, S Tuo, J Velkovska, Q Xu, M W Arenton, P Barria, B Cox, R Hirosky, A Ledovskoy, H Li, C Neu, T Sinthuprasith, X Sun, Y Wang, E Wolfe, F Xia, R Harr, P E Karchin, J Sturdy, S Zaleski, M Brodski, J Buchanan, C Caillol, S Dasu, L Dodd, S Duric, B Gomber, M Grothe, M Herndon, A Hervé, U Hussain, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, G A Pierro, G Polese, T Ruggles, A Savin, N Smith, W H Smith, D Taylor, N Woods
The prompt D^{0} meson azimuthal anisotropy coefficients, v_{2} and v_{3}, are measured at midrapidity (|y|<1.0) in Pb-Pb collisions at a center-of-mass energy sqrt[s_{NN}]=5.02  TeV per nucleon pair with data collected by the CMS experiment. The measurement is performed in the transverse momentum (p_{T}) range of 1 to 40  GeV/c, for central and midcentral collisions. The v_{2} coefficient is found to be positive throughout the p_{T} range studied. The first measurement of the prompt D^{0} meson v_{3} coefficient is performed, and values up to 0...
May 18, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29864318/search-for-the-x-5568-state-decaying-into-b_-s-0-%C3%AF-%C3%A2-in-proton-proton-collisions-at-sqrt-s-8-tev
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Dittmann, K Hatakeyama, H Liu, N Pastika, C Smith, R Bartek, A Dominguez, A Buccilli, S I Cooper, C Henderson, P Rumerio, C West, D Arcaro, A Avetisyan, T Bose, D Gastler, D Rankin, C Richardson, J Rohlf, L Sulak, D Zou, G Benelli, D Cutts, A Garabedian, M Hadley, J Hakala, U Heintz, J M Hogan, K H M Kwok, E Laird, G Landsberg, J Lee, Z Mao, M Narain, J Pazzini, S Piperov, S Sagir, R Syarif, D Yu, R Band, C Brainerd, R Breedon, D Burns, M Calderon De La Barca Sanchez, M Chertok, J Conway, R Conway, P T Cox, R Erbacher, C Flores, G Funk, W Ko, R Lander, C Mclean, M Mulhearn, D Pellett, J Pilot, S Shalhout, M Shi, J Smith, D Stolp, K Tos, M Tripathi, Z Wang, M Bachtis, C Bravo, R Cousins, A Dasgupta, A Florent, J Hauser, M Ignatenko, N Mccoll, S Regnard, D Saltzberg, C Schnaible, V Valuev, E Bouvier, K Burt, R Clare, J Ellison, J W Gary, S M A Ghiasi Shirazi, G Hanson, J Heilman, G Karapostoli, E Kennedy, F Lacroix, O R Long, M Olmedo Negrete, M I Paneva, W Si, L Wang, H Wei, S Wimpenny, B R Yates, J G Branson, S Cittolin, M Derdzinski, R Gerosa, D Gilbert, B Hashemi, A Holzner, D Klein, G Kole, V Krutelyov, J Letts, M Masciovecchio, D Olivito, S Padhi, M Pieri, M Sani, V Sharma, M Tadel, A Vartak, S Wasserbaech, J Wood, F Würthwein, A Yagil, G Zevi Della Porta, N Amin, R Bhandari, J Bradmiller-Feld, C Campagnari, A Dishaw, V Dutta, M Franco Sevilla, L Gouskos, R Heller, J Incandela, A Ovcharova, H Qu, J Richman, D Stuart, I Suarez, J Yoo, D Anderson, A Bornheim, J M Lawhorn, H B Newman, T Nguyen, C Pena, M Spiropulu, J R Vlimant, S Xie, Z Zhang, R Y Zhu, M B Andrews, T Ferguson, T Mudholkar, M Paulini, J Russ, M Sun, H Vogel, I Vorobiev, M Weinberg, J P Cumalat, W T Ford, F Jensen, A Johnson, M Krohn, S Leontsinis, T Mulholland, K Stenson, S R Wagner, J Alexander, J Chaves, J Chu, S Dittmer, K Mcdermott, N Mirman, J R Patterson, D Quach, A Rinkevicius, A Ryd, L Skinnari, L Soffi, S M Tan, Z Tao, J Thom, J Tucker, P Wittich, M Zientek, S Abdullin, M Albrow, M Alyari, G Apollinari, A Apresyan, A Apyan, S Banerjee, L A T Bauerdick, A Beretvas, J Berryhill, P C Bhat, G Bolla, K Burkett, J N Butler, A Canepa, G B Cerati, H W K Cheung, F Chlebana, M Cremonesi, J Duarte, V D Elvira, J Freeman, Z Gecse, E Gottschalk, L Gray, D Green, S Grünendahl, O Gutsche, R M Harris, S Hasegawa, J Hirschauer, Z Hu, B Jayatilaka, S Jindariani, M Johnson, U Joshi, B Klima, B Kreis, S Lammel, D Lincoln, R Lipton, M Liu, T Liu, R Lopes De Sá, J Lykken, K Maeshima, N Magini, J M Marraffino, D Mason, P McBride, P Merkel, S Mrenna, S Nahn, V O'Dell, K Pedro, O Prokofyev, G Rakness, L Ristori, B Schneider, E Sexton-Kennedy, A Soha, W J Spalding, L Spiegel, S Stoynev, J Strait, N Strobbe, L Taylor, S Tkaczyk, N V Tran, L Uplegger, E W Vaandering, C Vernieri, M Verzocchi, R Vidal, M Wang, H A Weber, A Whitbeck, D Acosta, P Avery, P Bortignon, D Bourilkov, A Brinkerhoff, A Carnes, M Carver, D Curry, R D Field, I K Furic, S V Gleyzer, B M Joshi, J Konigsberg, A Korytov, K Kotov, P Ma, K Matchev, H Mei, G Mitselmakher, K Shi, D Sperka, N Terentyev, L Thomas, J Wang, S Wang, J Yelton, Y R Joshi, S Linn, P Markowitz, J L Rodriguez, A Ackert, T Adams, A Askew, S Hagopian, V Hagopian, K F Johnson, T Kolberg, G Martinez, T Perry, H Prosper, A Saha, A Santra, V Sharma, R Yohay, M M Baarmand, V Bhopatkar, S Colafranceschi, M Hohlmann, D Noonan, T Roy, F Yumiceva, M R Adams, L Apanasevich, D Berry, R R Betts, R Cavanaugh, X Chen, O Evdokimov, C E Gerber, D A Hangal, D J Hofman, K Jung, J Kamin, I D Sandoval Gonzalez, M B Tonjes, H Trauger, N Varelas, H Wang, Z Wu, J Zhang, B Bilki, W Clarida, K Dilsiz, S Durgut, R P Gandrajula, M Haytmyradov, V Khristenko, J-P Merlo, H Mermerkaya, A Mestvirishvili, A Moeller, J Nachtman, H Ogul, Y Onel, F Ozok, A Penzo, C Snyder, E Tiras, J Wetzel, K Yi, B Blumenfeld, A Cocoros, N Eminizer, D Fehling, L Feng, A V Gritsan, P Maksimovic, J Roskes, U Sarica, M Swartz, M Xiao, C You, A Al-Bataineh, P Baringer, A Bean, S Boren, J Bowen, J Castle, S Khalil, A Kropivnitskaya, D Majumder, W Mcbrayer, M Murray, C Royon, S Sanders, E Schmitz, J D Tapia Takaki, Q Wang, A Ivanov, K Kaadze, Y Maravin, A Mohammadi, L K Saini, N Skhirtladze, F Rebassoo, D Wright, C Anelli, A Baden, O Baron, A Belloni, S C Eno, Y Feng, C Ferraioli, N J Hadley, S Jabeen, G Y Jeng, R G Kellogg, J Kunkle, A C Mignerey, F Ricci-Tam, Y H Shin, A Skuja, S C Tonwar, D Abercrombie, B Allen, V Azzolini, R Barbieri, A Baty, R Bi, S Brandt, W Busza, I A Cali, M D'Alfonso, Z Demiragli, G Gomez Ceballos, M Goncharov, D Hsu, M Hu, Y Iiyama, G M Innocenti, M Klute, D Kovalskyi, Y-J Lee, A Levin, P D Luckey, B Maier, A C Marini, C Mcginn, C Mironov, S Narayanan, X Niu, C Paus, C Roland, G Roland, J Salfeld-Nebgen, G S F Stephans, K Tatar, D Velicanu, J Wang, T W Wang, B Wyslouch, A C Benvenuti, R M Chatterjee, A Evans, P Hansen, J Hiltbrand, S Kalafut, Y Kubota, Z Lesko, J Mans, S Nourbakhsh, N Ruckstuhl, R Rusack, J Turkewitz, M A Wadud, J G Acosta, S Oliveros, E Avdeeva, K Bloom, D R Claes, C Fangmeier, F Golf, R Gonzalez Suarez, R Kamalieddin, I Kravchenko, J Monroy, J E Siado, G R Snow, B Stieger, J Dolen, A Godshalk, C Harrington, I Iashvili, D Nguyen, A Parker, S Rappoccio, B Roozbahani, G Alverson, E Barberis, C Freer, A Hortiangtham, A Massironi, D M Morse, T Orimoto, R Teixeira De Lima, D Trocino, T Wamorkar, B Wang, A Wisecarver, D Wood, S Bhattacharya, O Charaf, K A Hahn, N Mucia, N Odell, M H Schmitt, K Sung, M Trovato, M Velasco, R Bucci, N Dev, M Hildreth, K Hurtado Anampa, C Jessop, D J Karmgard, N Kellams, K Lannon, W Li, N Loukas, N Marinelli, F Meng, C Mueller, Y Musienko, M Planer, A Reinsvold, R Ruchti, P Siddireddy, G Smith, S Taroni, M Wayne, A Wightman, M Wolf, A Woodard, J Alimena, L Antonelli, B Bylsma, L S Durkin, S Flowers, B Francis, A Hart, C Hill, W Ji, B Liu, W Luo, B L Winer, H W Wulsin, S Cooperstein, O Driga, P Elmer, J Hardenbrook, P Hebda, S Higginbotham, A Kalogeropoulos, D Lange, J Luo, D Marlow, K Mei, I Ojalvo, J Olsen, C Palmer, P Piroué, D Stickland, C Tully, S Malik, S Norberg, A Barker, V E Barnes, S Das, S Folgueras, L Gutay, M K Jha, M Jones, A W Jung, A Khatiwada, D H Miller, N Neumeister, C C Peng, H Qiu, J F Schulte, J Sun, F Wang, R Xiao, W Xie, T Cheng, N Parashar, J Stupak, Z Chen, K M Ecklund, S Freed, F J M Geurts, M Guilbaud, M Kilpatrick, W Li, B Michlin, B P Padley, J Roberts, J Rorie, W Shi, Z Tu, J Zabel, A Zhang, A Bodek, P de Barbaro, R Demina, Y T Duh, T Ferbel, M Galanti, A Garcia-Bellido, J Han, O Hindrichs, A Khukhunaishvili, K H Lo, P Tan, M Verzetti, R Ciesielski, K Goulianos, C Mesropian, A Agapitos, J P Chou, Y Gershtein, T A Gómez Espinosa, E Halkiadakis, M Heindl, E Hughes, S Kaplan, R Kunnawalkam Elayavalli, S Kyriacou, A Lath, R Montalvo, K Nash, M Osherson, H Saka, S Salur, S Schnetzer, D Sheffield, S Somalwar, R Stone, S Thomas, P Thomassen, M Walker, A G Delannoy, J Heideman, G Riley, K Rose, S Spanier, K Thapa, O Bouhali, A Castaneda Hernandez, A Celik, M Dalchenko, M De Mattia, A Delgado, S Dildick, R Eusebi, J Gilmore, T Huang, T Kamon, R Mueller, Y Pakhotin, R Patel, A Perloff, L Perniè, D Rathjens, A Safonov, A Tatarinov, K A Ulmer, N Akchurin, J Damgov, F De Guio, P R Dudero, J Faulkner, E Gurpinar, S Kunori, K Lamichhane, S W Lee, T Libeiro, T Mengke, S Muthumuni, T Peltola, S Undleeb, I Volobouev, Z Wang, S Greene, A Gurrola, R Janjam, W Johns, C Maguire, A Melo, H Ni, K Padeken, P Sheldon, S Tuo, J Velkovska, Q Xu, M W Arenton, P Barria, B Cox, R Hirosky, M Joyce, A Ledovskoy, H Li, C Neu, T Sinthuprasith, Y Wang, E Wolfe, F Xia, R Harr, P E Karchin, N Poudyal, J Sturdy, P Thapa, S Zaleski, M Brodski, J Buchanan, C Caillol, S Dasu, L Dodd, S Duric, B Gomber, M Grothe, M Herndon, A Hervé, U Hussain, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, T Ruggles, A Savin, N Smith, W H Smith, D Taylor, N Woods
A search for resonancelike structures in the B_{s}^{0}π^{±} invariant mass spectrum is performed using proton-proton collision data collected by the CMS experiment at the LHC at sqrt[s]=8  TeV, corresponding to an integrated luminosity of 19.7  fb^{-1}. The B_{s}^{0} mesons are reconstructed in the decay chain B_{s}^{0}→J/ψϕ, with J/ψ→μ^{+}μ^{-} and ϕ→K^{+}K^{-}. The B_{s}^{0}π^{±} invariant mass distribution shows no statistically significant peaks for different selection requirements on the reconstructed B_{s}^{0} and π^{±} candidates...
May 18, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29861642/matching-adjusted-indirect-treatment-comparison-of-ribociclib-and-palbociclib-in-hr-her2-advanced-breast-cancer
#16
Gabriel Tremblay, David Chandiwana, Mike Dolph, Jaclyn Hearnden, Anna Forsythe, Mauricio Monaco
Background: Ribociclib (RIBO) and palbociclib (PALBO), combined with letrozole (LET), have been evaluated as treatments for hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer in separate Phase III randomized controlled trials (RCTs), but not head-to-head. Population differences can lead to biased results by classical indirect treatment comparison (ITC). Matching-adjusted indirect comparison (MAIC) aims to correct these differences. We compared RIBO and PALBO in hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer using MAIC...
2018: Cancer Management and Research
https://www.readbyqxmd.com/read/29850854/in-reply-quality-of-life-after-motor-cortex-stimulation-clinical-results-and-systematic-review-of-the-literature
#17
Daniella Parravano, Daniel Ciampi A de Andrade, Erich T Fonoff, Bernardo A Monaco, Jessie Navarro, Lin T Yeng, Manoel J Teixeira, Clement Hamani
No abstract text is available yet for this article.
May 30, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29807313/complex-networks-reveal-early-mri-markers-of-parkinson-s-disease
#18
Nicola Amoroso, Marianna La Rocca, Alfonso Monaco, Roberto Bellotti, Sabina Tangaro
Parkinson's disease (PD) is the most common neurological disorder, after Alzheimer's disease, and is characterized by a long prodromal stage lasting up to 20 years. As age is a prominent factor risk for the disease, next years will see a continuous increment of PD patients, making urgent the development of efficient strategies for early diagnosis and treatments. We propose here a novel approach based on complex networks for accurate early diagnoses using magnetic resonance imaging (MRI) data; our approach also allows us to investigate which are the brain regions mostly affected by the disease...
May 17, 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29806668/5-year-outcomes-after-coverage-of-soft-tissue-dehiscence-around-single-implants-a-prospective-cohort-study
#19
Giovanni Zucchelli, Pietro Felice, Claudio Mazzotti, Matteo Marzadori, Ilham Mounssif, Carlo Monaco, Stefanini Martina
PURPOSE: To report the 5-year clinical and aesthetic outcomes of a novel surgical-prosthetic approach for the treatment of buccal soft tissue dehiscence around single dental implants. MATERIALS AND METHODS: Twenty patients with buccal soft tissues dehiscence around single implants in the aesthetic area were treated by removing the implant-supported crown, reducing the implant abutment, coronally advanced flap in combination with connective tissue graft and final restoration...
2018: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/29800674/colonization-and-infection-due-to-carbapenemase-producing-enterobacteriaceae-in-liver-and-lung-transplant-recipients-and-donor-derived-transmission-a-prospective-cohort-study-conducted-in-italy
#20
Giulia Errico, Carlo Gagliotti, Monica Monaco, Lucia Masiero, Paolo Gaibani, Simone Ambretti, Maria Paola Landini, Silvia D'Arezzo, Antonino Di Caro, Saverio Giuseppe Parisi, Giorgio Palù, Francesca Vespasiano, Filomena Morsillo, Maria Luisa Moro, Francesco Procaccio, Andrea Ricci, Paolo Antonio Grossi, Annalisa Pantosti, Alessandro Nanni Costa
OBJECTIVE: A prospective cohort study was conducted in Italy in order to describe the microbiological aspects of colonization/infection by carbapenemase producing Enterobacteriaceae (CPE) in donors and recipients of lung and liver transplants and the possible CPE transmission from donors to recipients. METHODS: Between 15 January 2014-14 January 2015 all recipients of solid organ transplants (SOT) at 10 lung and 8 liver transplantation centres (TCs) and the corresponding donors were enrolled...
May 22, 2018: Clinical Microbiology and Infection
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