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Psychiatric Risk Assessments

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https://www.readbyqxmd.com/read/29676839/analgesic-consumption-trajectories-in-8-975-patients-1-year-after-fast-track-total-hip-or-knee-arthroplasty
#1
C C Jørgensen, M Petersen, H Kehlet, E K Aasvang
BACKGROUND: Persistent or increased long-term opioid consumption has previously been described following total hip- (THA) and knee arthroplasty (TKA). However, detailed information on postoperative analgesic consumption trajectories and risk factors associated with continued need of analgesics in fast-track THA and TKA is sparse. METHODS: Descriptive multicenter study in primary unilateral fast-track THA or TKA with prospective data on patient characteristics and information on reimbursement entitled dispensed prescriptions of paracetamol, non-steroidal anti-inflammatory drugs, opioids, anticonvulsants, and antidepressants one month preoperatively and one year postoperatively...
April 20, 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29675767/high-risk-for-severe-emotional-dysregulation-in-psychiatrically-referred-youth-with-autism-spectrum-disorder-a-controlled-study
#2
Gagan Joshi, Janet Wozniak, Maura Fitzgerald, Stephen Faraone, Ronna Fried, Maribel Galdo, Stephannie L Furtak, Kristina Conroy, J Ryan Kilcullen, Abigail Belser, Joseph Biederman
To assess prevalence and severity of emotional dysregulation (ED) in psychiatrically referred youth with autism spectrum disorder (ASD). ASD youth (N = 123) were compared to youth with attention-deficit/hyperactivity disorder (ADHD) and controls. The majority of psychiatrically referred youth with ASD had positive Child Behavior Checklist-ED (CBCL-ED) profile that was significantly higher than in youth with ADHD (82 vs. 53%; p < 0.001). The severe emotional dysregulation (SED) profile was significantly greater in ASD youth than ADHD (44 vs...
April 19, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29674979/emotional-responses-to-suicidal-patients-factor-structure-construct-and-predictive-validity-of-the-therapist-response-questionnaire-suicide-form
#3
Shira Barzilay, Zimri S Yaseen, Mariah Hawes, Bernard Gorman, Rachel Altman, Adriana Foster, Alan Apter, Paul Rosenfield, Igor Galynker
Background: Mental health professionals have a pivotal role in suicide prevention. However, they also often have intense emotional responses, or countertransference, during encounters with suicidal patients. Previous studies of the Therapist Response Questionnaire-Suicide Form (TRQ-SF), a brief novel measure aimed at probing a distinct set of suicide-related emotional responses to patients found it to be predictive of near-term suicidal behavior among high suicide-risk inpatients. The purpose of this study was to validate the TRQ-SF in a general outpatient clinic setting...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29674364/health-and-prevention-enhancement-h-peace-a-retrospective-population-based-cohort-study-conducted-at-the-seoul-national-university-hospital-gangnam-center-korea
#4
Changhyun Lee, Eun Kyung Choe, Ji Min Choi, Yunji Hwang, Young Lee, Boram Park, Su Jin Chung, Min-Sun Kwak, Jong-Eun Lee, Joo Sung Kim, Sue Kyung Park, Sang-Heon Cho
PURPOSE: The Health and Prevention Enhancement (H-PEACE) study was designed to investigate the association of diagnostic imaging results, biomarkers and the predisease stage of non-communicable diseases (NCDs), such as malignancies and metabolic diseases, in an average-risk population in Korea. PARTICIPANTS: This study enrolled a large-scale retrospective cohort at the Healthcare System Gangnam Center, Seoul National University Hospital, from October 2003 to December 2014...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29673069/short-term-memory-impairment-in-vestibular-patients-can-arise-independently-of-psychiatric-impairment-fatigue-and-sleeplessness
#5
Laura Smith, David Wilkinson, Mayur Bodani, Rowena Bicknell, S S Surenthiran
Vestibular dysfunction is associated with visual short-term memory impairment; however, it remains unclear if this impairment arises as a direct result of the vestibular dysfunction or is a consequence of comorbid changes in mood, affect, fatigue, and/or sleep. To this end, we assessed the concurrence and interdependence of these comorbidities in 101 individuals recruited from a tertiary balance clinic with a neuro-otological diagnosis. Over fifty per cent of the sample showed reduced visuospatial short-term memory, 60% and 37% exceeded cut-off on the Beck Anxiety and Depression Inventories, respectively, 70% exceeded cut-off on the Fatigue Severity Scale, 44% reported daytime sleepiness on the Epworth Sleepiness Scale, and 78% scored above cut-off on the Pittsburgh Sleep Quality Index...
April 19, 2018: Journal of Neuropsychology
https://www.readbyqxmd.com/read/29671935/a-data-driven-investigation-of-relationships-between-bipolar-psychotic-symptoms-and-schizophrenia-genome-wide-significant-genetic-loci
#6
Ganna Leonenko, Arianna Di Florio, Judith Allardyce, Liz Forty, Sarah Knott, Lisa Jones, Katherine Gordon-Smith, Michael J Owen, Ian Jones, James Walters, Nick Craddock, Michael C O'Donovan, Valentina Escott-Price
The etiologies of bipolar disorder (BD) and schizophrenia include a large number of common risk alleles, many of which are shared across the disorders. BD is clinically heterogeneous and it has been postulated that the pattern of symptoms is in part determined by the particular risk alleles carried, and in particular, that risk alleles also confer liability to schizophrenia influence psychotic symptoms in those with BD. To investigate links between psychotic symptoms in BD and schizophrenia risk alleles we employed a data-driven approach in a genotyped and deeply phenotyped sample of subjects with BD...
April 19, 2018: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/29669907/mild-tbi-and-risk-of-parkinson-disease-a-chronic-effects-of-neurotrauma-consortium-study
#7
Raquel C Gardner, Amy L Byers, Deborah E Barnes, Yixia Li, John Boscardin, Kristine Yaffe
OBJECTIVE: Our aim was to assess risk of Parkinson disease (PD) following traumatic brain injury (TBI), including specifically mild TBI (mTBI), among care recipients in the Veterans Health Administration. METHODS: In this retrospective cohort study, we identified all patients with a TBI diagnosis in Veterans Health Administration databases from October 2002 to September 2014 and age-matched 1:1 to a random sample of patients without TBI. All patients were aged 18 years and older without PD or dementia at baseline...
April 18, 2018: Neurology
https://www.readbyqxmd.com/read/29669557/discovery-biology-of-neuropsychiatric-syndromes-dbns-a-center-for-integrating-clinical-medicine-and-basic-science
#8
Biju Viswanath, Naren P Rao, Janardhanan C Narayanaswamy, Palanimuthu T Sivakumar, Arun Kandasamy, Muralidharan Kesavan, Urvakhsh Meherwan Mehta, Ganesan Venkatasubramanian, John P John, Odity Mukherjee, Meera Purushottam, Ramakrishnan Kannan, Bhupesh Mehta, Thennarasu Kandavel, B Binukumar, Jitender Saini, Deepak Jayarajan, A Shyamsundar, Sydney Moirangthem, K G Vijay Kumar, Jagadisha Thirthalli, Prabha S Chandra, Bangalore N Gangadhar, Pratima Murthy, Mitradas M Panicker, Upinder S Bhalla, Sumantra Chattarji, Vivek Benegal, Mathew Varghese, Janardhan Y C Reddy, Padinjat Raghu, Mahendra Rao, Sanjeev Jain
BACKGROUND: There is emerging evidence that there are shared genetic, environmental and developmental risk factors in psychiatry, that cut across traditional diagnostic boundaries. With this background, the Discovery biology of neuropsychiatric syndromes (DBNS) proposes to recruit patients from five different syndromes (schizophrenia, bipolar disorder, obsessive compulsive disorder, Alzheimer's dementia and substance use disorders), identify those with multiple affected relatives, and invite these families to participate in this study...
April 18, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29665736/fear-avoidance-and-clinical-outcomes-from-mild-traumatic-brain-injury
#9
Noah D Silverberg, William Panenka, Grant L Iverson
Characterizing psychological factors that contribute to persistent symptoms after mild traumatic brain injury (MTBI) can inform early intervention. To determine whether fear avoidance, a known risk factor for chronic disability after musculoskeletal injury, is associated with worse clinical outcomes from MTBI, adults were recruited from four outpatient MTBI clinics and assessed at their first clinic visit (M=2.7, SD=1.5 weeks post-injury) and again 4-5 months later. Of 273 patients screened, 102 completed the initial assessment and 87 returned for the outcome assessment...
April 18, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29665518/early-intervention-for-adolescents-at-risk-for-bipolar-disorder-a-pilot-randomized-trial-of-interpersonal-and-social-rhythm-therapy-ipsrt
#10
Tina R Goldstein, John Merranko, Megan Krantz, Matthew Garcia, Peter Franzen, Jessica Levenson, David Axelson, Boris Birmaher, Ellen Frank
OBJECTIVE: To conduct a pilot randomized trial of Interpersonal and Social Rhythm Therapy plus Data-Informed Referral (IPSRT + DIR) versus DIR-alone for adolescents at-risk for bipolar disorder (BP). METHOD: Eligible participants included youth (12-18) with a BP parent; youth with BP were excluded. Participants (n = 42) were randomized to receive IPSRT + DIR to treat any psychiatric disorders present at baseline, or DIR-alone. A blind evaluator assessed outcomes at baseline, 3- and 6-months...
April 7, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29665120/determinants-and-predictive-value-of-clinician-assessment-of-short-term-suicide-risk
#11
Shira Barzilay, Zimri S Yaseen, Mariah Hawes, Irina Kopeykina, Firouz Ardalan, Paul Rosenfield, James Murrough, Igor Galynker
We examine the interrelations among clinicians' judgment of patients' suicide risk, clinicians' emotional responses, and standard risk factors in the short-term prediction of suicidal thoughts and behaviors. Psychiatric outpatients (n = 153) with a lifetime history of suicide ideation/attempt and their treating clinicians (n = 67) were evaluated at intake. Clinicians completed a standard suicide risk instrument (modified SAD PERSONS scale), a 10-point Likert scale assessment of judgment of patient suicide risk (Clinician Prediction Scale), and a measure of their emotional responses to the patient (Therapist Response Questionnaire-Suicide Form)...
April 17, 2018: Suicide & Life-threatening Behavior
https://www.readbyqxmd.com/read/29665048/a-neural-biomarker-the-error-related-negativity-predicts-the-first-onset-of-generalized-anxiety-disorder-in-a-large-sample-of-adolescent-females
#12
Alexandria Meyer, Brady Nelson, Greg Perlman, Daniel N Klein, Roman Kotov
OBJECTIVE: An increased neural response to making mistakes has emerged as a potential biomarker of anxiety across development. The error-related negativity (ERN) is an event-related potential elicited when people make mistakes on simple laboratory-based reaction time tasks that has been associated with risk for anxiety. This study examined whether the ERN prospectively predicted the first onset of generalized anxiety disorder (GAD) over 1.5 years in adolescent girls. METHODS: The sample included 457 girls between the ages of 13...
April 17, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29664050/association-between-perceived-stressfulness-of-stressful-life-events-and-the-suicidal-risk-in-chinese-patients-with-major-depressive-disorder
#13
Jing-Yu Lin, Yu Huang, Yun-Ai Su, Xin Yu, Xiao-Zhen Lyu, Qi Liu, Tian-Mei Si
Background: Patients with major depressive disorder (MDD) usually have high risk of suicidality. Few studies have investigated the effects of stressful life events (SLEs) on the risk of suicide in Chinese patients who have developed MDD. This study aimed to investigate the impact of SLEs on suicidal risk in Chinese patients with MDD. Methods: In total, 1029 patients with MDD were included from nine psychiatric hospitals to evaluate the impact of SLEs on suicidal risk...
April 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29658982/behavioural-changes-in-patients-with-intellectual-disability-treated-with-brivaracetam
#14
E Andres, F Kerling, H Hamer, M Winterholler
OBJECTIVE: The purpose of this study was to evaluate the tolerability and efficacy of brivaracetam (BRV) in residential patients at our epilepsy centre. PATIENTS AND METHODS: We assessed retrospectively 33 patients (14 females; mean age 38.2 years, with range 17-63 years) with intellectual disability (ID) and drug-resistant epilepsy using an industry-independent, non-interventional study design based on standardized daily seizure records. Mean seizure frequency was compared between the 3-month baseline period and subsequent 3-month treatment period...
April 16, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29656729/-false-positive-self-reported-psychotic-experiences-in-the-general-population-an-investigation-of-outcome-predictive-factors-and-clinical-relevance
#15
Y van der Steen, I Myin-Germeys, M van Nierop, M Ten Have, R de Graaf, S van Dorsselaer, J van Os, R van Winkel
AIMS: Self-reported psychotic experiences (SRPE) by individuals from the general population are often unconfirmed by clinical interview and referred to as 'false-positive' (FP) SRPE. FP SRPE have been suggested to represent the mildest form of risk along the extended psychosis continuum. However, little is known about their (clinical) outcome and evolution over time. Aims of this study were to prospectively examine, in individuals with FP SRPE, (1) the prevalence of remission, persistence and transition to validated PE at 3-year follow-up; (2) potential baseline psychopathological and psychosocial predictors of persistence of FP SRPE and transition to validated PE; and (3) whether those with persistent FP SRPE and validated PE already differed on psychopathology and psychosocial factors at baseline...
April 16, 2018: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/29656664/epigenetic-aging-in-major-depressive-disorder
#16
Laura K M Han, Moji Aghajani, Shaunna L Clark, Robin F Chan, Mohammad W Hattab, Andrey A Shabalin, Min Zhao, Gaurav Kumar, Lin Ying Xie, Rick Jansen, Yuri Milaneschi, Brian Dean, Karolina A Aberg, Edwin J C G van den Oord, Brenda W J H Penninx
OBJECTIVE: Major depressive disorder is associated with an increased risk of mortality and aging-related diseases. The authors examined whether major depression is associated with higher epigenetic aging in blood as measured by DNA methylation (DNAm) patterns, whether clinical characteristics of major depression have a further impact on these patterns, and whether the findings replicate in brain tissue. METHOD: DNAm age was estimated using all methylation sites in blood of 811 depressed patients and 319 control subjects with no lifetime psychiatric disorders and low depressive symptoms from the Netherlands Study of Depression and Anxiety...
April 16, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29655971/predictive-validity-and-gender-differences-in-a-biopsychosocial-model-of-violence-risk-assessment-in-acute-psychiatry
#17
Bjørn Magne S Eriksen, Ann Færden, Øyvind Lockertsen, Stål Bjørkly, John Olav Roaldset
Current violence risk assessment methods seem to have reached an upper limit of accuracy. More comprehensive biopsychosocial models may improve on existing methods. Research on gender differences concerning risk factors of violence is scarce and inconclusive. In this prospective study from an acute psychiatric ward, all patients admitted from March 2012 to March 2013 were included. Predictive validity and potential gender differences in a biopsychosocial model of violence risk assessment consisting of a psychosocial checklist (Violence risk screening-10, V-RISK-10), a patient's self-report risk scale (SRS), total cholesterol (TC) and high-density lipoprotein cholesterol (HDL) were examined in an inpatient (N = 348) and a 3-months follow-up (N = 101) sample...
April 9, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29655970/suicide-after-hospital-contact-for-psychiatric-assessment-in-hong-kong-a-long-term-cohort-study
#18
Chi-Ming Leung, Sing Lee, Dominic T S Lee, Connie T Y Yan, John So, Gabor S Ungvari, Chee H Ng, Yu-Tao Xiang
There are few long-term studies on suicide in psychiatric settings in China. The objective of this study was to evaluate the long term suicide risk and its associated factors after the initial psychiatric assessment. Demographic and clinical data of adult subjects receiving psychiatric assessment between 1996 and 2000 in a district hospital in Hong Kong were retrieved from the hospital computer system. Data were matched with completed suicides before June 30 2015 as recorded by the Coroner's Office. From a total of 4078 subjects identified, there were 152 (3...
April 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29651622/utilization-of-psychiatric-care-and-antidepressants-among-people-with-different-severity-of-depression-a-population-based-cohort-study-in-stockholm-sweden
#19
Yuying Sun, Jette Möller, Andreas Lundin, Samuel Y S Wong, Benjamin H K Yip, Yvonne Forsell
PURPOSE: To identify how severity of depression predicts future utilization of psychiatric care and antidepressants. METHODS: Data derived from a longitudinal population-based study in Stockholm, Sweden, include 10443 participants aged 20-64 years. Depression was assessed by Major Depression Inventory and divided into subsyndromal, mild, moderate and severe depression. Outcomes were the first time of hospitalization, specialized outpatient care and prescribed drugs obtained from national register records...
April 12, 2018: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/29650741/help-for-behaviours-that-challenge-in-adults-with-intellectual-and-developmental-disabilities
#20
REVIEW
Laurie Green, Karen McNeil, Marika Korossy, Kerry Boyd, Elizabeth Grier, MacKenzie Ketchell, Alvin Loh, Yona Lunsky, Shirley McMillan, Amanda Sawyer, Anupam Thakur, Elspeth Bradley
OBJECTIVE: To provide primary care physicians with an understanding of the causes of behaviours that challenge (BTC) in adults with intellectual and developmental disabilities (IDD), as presented in the 2018 Canadian consensus guidelines for primary care of adults with IDD; to offer a systematic approach to the assessment and treatment of such behaviours; and to link to tools to support these assessments. SOURCES OF INFORMATION: This review elaborates upon guidelines 26 to 29 in the mental health section of the 2018 Canadian consensus guidelines...
April 2018: Canadian Family Physician Médecin de Famille Canadien
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